DK3151832T3 - Fremgangsmåder til øgning af tonisk hæmning og behandling af sekundær søvnløshed - Google Patents

Fremgangsmåder til øgning af tonisk hæmning og behandling af sekundær søvnløshed Download PDF

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Publication number
DK3151832T3
DK3151832T3 DK15803364.7T DK15803364T DK3151832T3 DK 3151832 T3 DK3151832 T3 DK 3151832T3 DK 15803364 T DK15803364 T DK 15803364T DK 3151832 T3 DK3151832 T3 DK 3151832T3
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DK
Denmark
Prior art keywords
sleepness
procedures
treatment
tonic inhibition
increase tonic
Prior art date
Application number
DK15803364.7T
Other languages
Danish (da)
English (en)
Inventor
Matthew During
Original Assignee
Ovid Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ovid Therapeutics Inc filed Critical Ovid Therapeutics Inc
Application granted granted Critical
Publication of DK3151832T3 publication Critical patent/DK3151832T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
DK15803364.7T 2014-06-06 2015-06-03 Fremgangsmåder til øgning af tonisk hæmning og behandling af sekundær søvnløshed DK3151832T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462008939P 2014-06-06 2014-06-06
PCT/US2015/034018 WO2015187851A1 (en) 2014-06-06 2015-06-03 Methods of increasing tonic inhibition and treating secondary insomnia

Publications (1)

Publication Number Publication Date
DK3151832T3 true DK3151832T3 (da) 2021-06-14

Family

ID=54767324

Family Applications (2)

Application Number Title Priority Date Filing Date
DK18169211.2T DK3372229T3 (da) 2014-06-06 2015-06-03 Fremgangsmåder til øgning af tonisk hæmning og behandling af angelmans syndrom
DK15803364.7T DK3151832T3 (da) 2014-06-06 2015-06-03 Fremgangsmåder til øgning af tonisk hæmning og behandling af sekundær søvnløshed

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK18169211.2T DK3372229T3 (da) 2014-06-06 2015-06-03 Fremgangsmåder til øgning af tonisk hæmning og behandling af angelmans syndrom

Country Status (20)

Country Link
US (11) US20150352085A1 (enExample)
EP (3) EP3372229B1 (enExample)
JP (4) JP2017516868A (enExample)
AR (1) AR100772A1 (enExample)
AU (4) AU2015269667B2 (enExample)
CA (1) CA2950845C (enExample)
CY (2) CY1124368T1 (enExample)
DK (2) DK3372229T3 (enExample)
ES (2) ES2875742T3 (enExample)
HR (2) HRP20210901T1 (enExample)
HU (2) HUE055400T2 (enExample)
IL (2) IL249287B (enExample)
LT (2) LT3372229T (enExample)
MX (2) MX391502B (enExample)
PL (2) PL3151832T3 (enExample)
PT (2) PT3372229T (enExample)
RS (2) RS62006B1 (enExample)
SI (2) SI3372229T1 (enExample)
SM (2) SMT202100340T1 (enExample)
WO (1) WO2015187851A1 (enExample)

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HUE055400T2 (hu) 2014-06-06 2021-11-29 Ovid Therapeutics Inc Módszerek a tónusos gátlás növelésére és az Angelman-szindróma kezelésére
US10434308B2 (en) 2015-05-29 2019-10-08 Medtronic, Inc. Impedance matching and electrode conditioning in patient interface systems
US10080898B2 (en) 2015-05-29 2018-09-25 Medtronic, Inc. Simultaneous physiological sensing and stimulation with saturation detection
HK1250951A1 (zh) * 2015-07-17 2019-01-18 奥维德医疗公司 用加波沙朵治疗发育障碍的方法
US9682069B2 (en) 2015-07-17 2017-06-20 Ovid Therapeutics Inc Methods of treating Dravet syndrome
WO2018017639A1 (en) * 2016-07-19 2018-01-25 Georgia State University Research Foundation Methods for treating rett syndrome
EP3481387A4 (en) 2016-08-11 2020-04-08 Ovid Therapeutics Inc METHODS AND COMPOSITIONS FOR THE TREATMENT OF EPLEPTIC DISORDERS
CA3043626A1 (en) * 2016-11-22 2018-05-31 Ovid Therapeutics Inc. Methods of treating attention deficit/hyperactivity disorder with gaboxadol
US10071083B2 (en) 2017-02-03 2018-09-11 Ovid Therapeutics Inc Use of gaboxadol in the treatment of tinnitus
US20180338959A1 (en) * 2017-05-24 2018-11-29 Ovid Therapeutics Inc. Treatment of depressive disorders
MX2020001342A (es) 2017-08-04 2020-08-31 Ovid Therapeutics Inc Uso de gaboxadol en el tratamiento contra diabetes y afecciones relacionadas.
US11181384B2 (en) * 2018-07-23 2021-11-23 Waymo Llc Verifying map data using challenge questions
EP3833351A4 (en) 2018-09-20 2021-10-13 Ovid Therapeutics Inc. USE OF GABOXADOL FOR THE TREATMENT OF GILLES DE LA TOURETTE SYNDROME, TICS AND STATTING
WO2020106927A1 (en) 2018-11-21 2020-05-28 Certego Therapeutics Gaboxadol for reducing risk of suicide and rapid relief of depression
AU2019405489A1 (en) 2018-12-17 2021-06-10 Ovid Therapeutics Inc. Use of gaboxadol for the treatment of non-24 hour sleep-wake disorder
US11786694B2 (en) 2019-05-24 2023-10-17 NeuroLight, Inc. Device, method, and app for facilitating sleep
KR20220035195A (ko) * 2019-07-15 2022-03-21 오비드 테라퓨틱스 인크. 치료적 치료를 위한 가복사돌을 포함하는 약학적 제제
IL293924A (en) * 2019-12-18 2022-08-01 Ovid Therapeutics Inc Gaboxadol for therapeutic treatment of 1p36 deletion syndrome
US11597726B2 (en) 2020-05-20 2023-03-07 Certego Therapeutics Inc. Ring deuterated gaboxadol and its use for the treatment of psychiatric disorders
JP7600661B2 (ja) * 2020-12-11 2024-12-17 artience株式会社 貼付剤
US20240285562A1 (en) * 2023-02-17 2024-08-29 Ovid Therapeutics Inc. Use of (s)-3-amino-4-(difluoromethylenyl) cyclopent-1-ene-1-carboxylic acid in the treatment of multiple sclerosis

Family Cites Families (18)

* Cited by examiner, † Cited by third party
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DK270278A (da) 1977-06-20 1978-12-21 Krogsgaard Larsen P Cycliske aminosyrer
US4362731A (en) 1980-09-01 1982-12-07 Sandoz Ltd. Myotonolytic use of 4,5,6,7-tetrahydroisoxazolo [5,4-c] pyridin-3-ol and derivatives thereof
US4353910A (en) 1981-11-27 1982-10-12 Kefalas A/S Derivatives of 4,5,6,7-tetrahydroisoxazolo [5,4-c] pyridine-3-one, pharmaceutical compositions and methods of treatment
DE19525598C2 (de) * 1995-07-13 1997-09-25 Max Planck Gesellschaft Schlafmittel
DE19526864A1 (de) 1995-07-22 1997-01-23 Labtec Gmbh Hormonpflaster
US6461644B1 (en) 1996-03-25 2002-10-08 Richard R. Jackson Anesthetizing plastics, drug delivery plastics, and related medical products, systems and methods
US5948433A (en) 1997-08-21 1999-09-07 Bertek, Inc. Transdermal patch
US6676961B1 (en) 2002-03-06 2004-01-13 Automated Carrier Technologies, Inc. Transdermal patch assembly
US20050137222A1 (en) * 2003-12-18 2005-06-23 H. Lundbeck A/S Treatment of insomnia in human patients
JP2007530604A (ja) 2004-04-02 2007-11-01 ハー・ルンドベック・アクチエゼルスカベット 呼吸機能障害の治療
DE102005020882A1 (de) * 2005-05-04 2006-11-09 Dömling, Alexander, Dr. Verwendung von Gaboxadol und Derivaten zur Behandlung von Kinase-induzierten Krankheiten
US20110046090A1 (en) * 2005-10-31 2011-02-24 Braincells Inc. Modulation of neurogenesis with gaba agents and gaba analogs
US20090143335A1 (en) 2007-10-29 2009-06-04 H. Lundbeck A/S Modified absorption formulation of gaboxadol
US9399012B2 (en) 2007-11-13 2016-07-26 Mallinckrodt Ip Reduced dose intravenous acetaminophen
EP2334299A1 (en) * 2008-09-01 2011-06-22 H. Lundbeck A/S Pharmaceutical composition comprising gaboxadol and an inhibitor of patl or oat
HUE055400T2 (hu) 2014-06-06 2021-11-29 Ovid Therapeutics Inc Módszerek a tónusos gátlás növelésére és az Angelman-szindróma kezelésére
HK1250951A1 (zh) * 2015-07-17 2019-01-18 奥维德医疗公司 用加波沙朵治疗发育障碍的方法
US9399034B1 (en) 2015-08-11 2016-07-26 Ovid Therapeutics Inc Methods of sedation during critical care treatment

Also Published As

Publication number Publication date
US11278529B2 (en) 2022-03-22
IL249287B (en) 2021-03-25
LT3372229T (lt) 2021-07-12
EP3372229A1 (en) 2018-09-12
HUE055400T2 (hu) 2021-11-29
US20220016091A1 (en) 2022-01-20
IL249287A0 (en) 2017-02-28
HRP20210902T1 (hr) 2021-09-17
MX391502B (es) 2025-03-21
AU2020217342B2 (en) 2021-10-07
PL3372229T3 (pl) 2021-10-04
HRP20210901T1 (hr) 2021-09-17
US9339495B2 (en) 2016-05-17
US20170273956A1 (en) 2017-09-28
US20160038469A1 (en) 2016-02-11
DK3372229T3 (da) 2021-06-14
AU2024202604A1 (en) 2024-05-09
US9446028B2 (en) 2016-09-20
MX380868B (es) 2025-03-12
AU2015269667A1 (en) 2016-12-22
MX2016016136A (es) 2017-07-05
LT3151832T (lt) 2021-07-12
US20170087133A1 (en) 2017-03-30
JP2023123442A (ja) 2023-09-05
EP3151832A4 (en) 2018-01-17
US20160228418A1 (en) 2016-08-11
WO2015187851A1 (en) 2015-12-10
US20180015076A1 (en) 2018-01-18
US9801864B2 (en) 2017-10-31
AR100772A1 (es) 2016-11-02
SI3151832T1 (sl) 2021-08-31
US20250025448A1 (en) 2025-01-23
SMT202100340T1 (it) 2021-07-12
PT3372229T (pt) 2021-06-17
EP3151832B1 (en) 2021-03-24
SI3372229T1 (sl) 2021-09-30
RS62007B1 (sr) 2021-07-30
JP2021178836A (ja) 2021-11-18
AU2020217342A1 (en) 2020-08-27
MX2020012404A (es) 2022-04-11
EP3372229B1 (en) 2021-03-24
JP2020063264A (ja) 2020-04-23
EP3151832A1 (en) 2017-04-12
RS62006B1 (sr) 2021-07-30
ES2875742T3 (es) 2021-11-11
ES2876350T3 (es) 2021-11-12
PL3151832T3 (pl) 2021-10-25
IL268960B (en) 2021-05-31
US20150352085A1 (en) 2015-12-10
IL268960A (en) 2019-10-31
CA2950845A1 (en) 2015-12-10
CY1124368T1 (el) 2022-07-22
AU2015269667B2 (en) 2020-07-30
SMT202100343T1 (it) 2021-07-12
JP2017516868A (ja) 2017-06-22
US9744159B2 (en) 2017-08-29
CY1124366T1 (el) 2022-07-22
US20180303805A1 (en) 2018-10-25
US20170071917A1 (en) 2017-03-16
PT3151832T (pt) 2021-06-15
US20230051859A1 (en) 2023-02-16
AU2022200085A1 (en) 2022-02-03
CA2950845C (en) 2023-04-25
HUE055155T2 (hu) 2021-11-29
EP3795156A1 (en) 2021-03-24

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