ES2875742T3 - Métodos para aumentar la inhibición tónica y tratamiento del síndrome de Angelman - Google Patents

Métodos para aumentar la inhibición tónica y tratamiento del síndrome de Angelman Download PDF

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Publication number
ES2875742T3
ES2875742T3 ES18169211T ES18169211T ES2875742T3 ES 2875742 T3 ES2875742 T3 ES 2875742T3 ES 18169211 T ES18169211 T ES 18169211T ES 18169211 T ES18169211 T ES 18169211T ES 2875742 T3 ES2875742 T3 ES 2875742T3
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Spain
Prior art keywords
composition
drug
thip
use according
pharmaceutically acceptable
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ES18169211T
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English (en)
Spanish (es)
Inventor
Matthew During
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Ovid Therapeutics Inc
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Ovid Therapeutics Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
ES18169211T 2014-06-06 2015-06-03 Métodos para aumentar la inhibición tónica y tratamiento del síndrome de Angelman Active ES2875742T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462008939P 2014-06-06 2014-06-06

Publications (1)

Publication Number Publication Date
ES2875742T3 true ES2875742T3 (es) 2021-11-11

Family

ID=54767324

Family Applications (2)

Application Number Title Priority Date Filing Date
ES18169211T Active ES2875742T3 (es) 2014-06-06 2015-06-03 Métodos para aumentar la inhibición tónica y tratamiento del síndrome de Angelman
ES15803364T Active ES2876350T3 (es) 2014-06-06 2015-06-03 Métodos para aumentar la inhibición tónica y tratamiento del insomnio secundario

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES15803364T Active ES2876350T3 (es) 2014-06-06 2015-06-03 Métodos para aumentar la inhibición tónica y tratamiento del insomnio secundario

Country Status (20)

Country Link
US (11) US20150352085A1 (enExample)
EP (3) EP3795156A1 (enExample)
JP (4) JP2017516868A (enExample)
AR (1) AR100772A1 (enExample)
AU (4) AU2015269667B2 (enExample)
CA (1) CA2950845C (enExample)
CY (2) CY1124368T1 (enExample)
DK (2) DK3372229T3 (enExample)
ES (2) ES2875742T3 (enExample)
HR (2) HRP20210901T1 (enExample)
HU (2) HUE055400T2 (enExample)
IL (2) IL249287B (enExample)
LT (2) LT3151832T (enExample)
MX (2) MX380868B (enExample)
PL (2) PL3151832T3 (enExample)
PT (2) PT3151832T (enExample)
RS (2) RS62006B1 (enExample)
SI (2) SI3372229T1 (enExample)
SM (2) SMT202100343T1 (enExample)
WO (1) WO2015187851A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS62006B1 (sr) 2014-06-06 2021-07-30 Ovid Therapeutics Inc Postupci pojačavanja tonične inhibicije i lečenja sekundarne nesanice
US10080898B2 (en) 2015-05-29 2018-09-25 Medtronic, Inc. Simultaneous physiological sensing and stimulation with saturation detection
US10434308B2 (en) 2015-05-29 2019-10-08 Medtronic, Inc. Impedance matching and electrode conditioning in patient interface systems
US9682069B2 (en) 2015-07-17 2017-06-20 Ovid Therapeutics Inc Methods of treating Dravet syndrome
MX391708B (es) 2015-07-17 2025-03-21 Ovid Therapeutics Inc Metodos para tratar trastornos del desarrollo con gaboxadol.
WO2018017639A1 (en) * 2016-07-19 2018-01-25 Georgia State University Research Foundation Methods for treating rett syndrome
KR102518846B1 (ko) 2016-08-11 2023-04-05 오비드 테라퓨틱스 인크. 간질 장애의 치료를 위한 방법 및 조성물
JP2019535760A (ja) * 2016-11-22 2019-12-12 オービッド・セラピューティクス・インコーポレイテッドOvid Therapeutics Inc. フルピルチンを用いた発達障害および/または発作性障害の処置方法
US10071083B2 (en) * 2017-02-03 2018-09-11 Ovid Therapeutics Inc Use of gaboxadol in the treatment of tinnitus
US20180338959A1 (en) * 2017-05-24 2018-11-29 Ovid Therapeutics Inc. Treatment of depressive disorders
EP3648762A4 (en) 2017-08-04 2021-03-24 Ovid Therapeutics, Inc. USE OF GABOXADOL IN THE TREATMENT OF DIABETES AND RELATED DISEASES
US11181384B2 (en) * 2018-07-23 2021-11-23 Waymo Llc Verifying map data using challenge questions
EP3833351A4 (en) * 2018-09-20 2021-10-13 Ovid Therapeutics Inc. USE OF GABOXADOL FOR THE TREATMENT OF GILLES DE LA TOURETTE SYNDROME, TICS AND STATTING
BR112021009944A2 (pt) * 2018-11-21 2021-08-17 Certego Therapeutics Inc. gaboxadol para reduzir risco de suicídio e alívio rápido de depressão
KR20210105387A (ko) 2018-12-17 2021-08-26 오비드 테라퓨틱스 인크. 비-24 시간 수면-각성 장애의 치료를 위한 가복사돌의 사용
US11786694B2 (en) 2019-05-24 2023-10-17 NeuroLight, Inc. Device, method, and app for facilitating sleep
CA3146737A1 (en) * 2019-07-15 2021-01-21 Ovid Therapeutics Inc. Pharmaceutical formulations containing gaboxadol for therapeutic treatment
AU2020405060A1 (en) * 2019-12-18 2022-06-09 Ovid Therapeutics Inc. Gaboxadol for therapeutic treatment of 1p36 deletion syndrome
JP2023526439A (ja) 2020-05-20 2023-06-21 セルテゴ セラピューティクス インコーポレイテッド 精神障害の処置のための環重水素化ガボキサドールおよびその使用
JP7600661B2 (ja) * 2020-12-11 2024-12-17 artience株式会社 貼付剤
AU2024220869A1 (en) * 2023-02-17 2025-09-04 Ovid Therapeutics Inc. Use of (s)-3-amino-4-(difluoromethylenyl) cyclopent-1-ene-1-carboxylic acid in the treatment of multiple sclerosis

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DK270378A (da) 1977-06-20 1978-12-21 Krogsgaard Larsen P Isoxazolderivater
US4362731A (en) 1980-09-01 1982-12-07 Sandoz Ltd. Myotonolytic use of 4,5,6,7-tetrahydroisoxazolo [5,4-c] pyridin-3-ol and derivatives thereof
US4353910A (en) 1981-11-27 1982-10-12 Kefalas A/S Derivatives of 4,5,6,7-tetrahydroisoxazolo [5,4-c] pyridine-3-one, pharmaceutical compositions and methods of treatment
DE19525598C2 (de) * 1995-07-13 1997-09-25 Max Planck Gesellschaft Schlafmittel
DE19526864A1 (de) 1995-07-22 1997-01-23 Labtec Gmbh Hormonpflaster
US6461644B1 (en) 1996-03-25 2002-10-08 Richard R. Jackson Anesthetizing plastics, drug delivery plastics, and related medical products, systems and methods
US5948433A (en) 1997-08-21 1999-09-07 Bertek, Inc. Transdermal patch
US6676961B1 (en) 2002-03-06 2004-01-13 Automated Carrier Technologies, Inc. Transdermal patch assembly
US20050137222A1 (en) * 2003-12-18 2005-06-23 H. Lundbeck A/S Treatment of insomnia in human patients
AU2005229493A1 (en) 2004-04-02 2005-10-13 H. Lundbeck A/S Treatment of impaired respiratory function with gaboxadol
DE102005020882A1 (de) * 2005-05-04 2006-11-09 Dömling, Alexander, Dr. Verwendung von Gaboxadol und Derivaten zur Behandlung von Kinase-induzierten Krankheiten
US20110046090A1 (en) * 2005-10-31 2011-02-24 Braincells Inc. Modulation of neurogenesis with gaba agents and gaba analogs
US20090143335A1 (en) 2007-10-29 2009-06-04 H. Lundbeck A/S Modified absorption formulation of gaboxadol
WO2009064928A1 (en) 2007-11-13 2009-05-22 Cadence Pharmaceuticals Reduced dose intravenous acetaminophen
EP2334299A1 (en) * 2008-09-01 2011-06-22 H. Lundbeck A/S Pharmaceutical composition comprising gaboxadol and an inhibitor of patl or oat
RS62006B1 (sr) * 2014-06-06 2021-07-30 Ovid Therapeutics Inc Postupci pojačavanja tonične inhibicije i lečenja sekundarne nesanice
MX391708B (es) * 2015-07-17 2025-03-21 Ovid Therapeutics Inc Metodos para tratar trastornos del desarrollo con gaboxadol.
US9399034B1 (en) 2015-08-11 2016-07-26 Ovid Therapeutics Inc Methods of sedation during critical care treatment

Also Published As

Publication number Publication date
SMT202100340T1 (it) 2021-07-12
DK3372229T3 (da) 2021-06-14
US20180303805A1 (en) 2018-10-25
MX380868B (es) 2025-03-12
SMT202100343T1 (it) 2021-07-12
HRP20210902T1 (hr) 2021-09-17
EP3151832A4 (en) 2018-01-17
PT3372229T (pt) 2021-06-17
CA2950845A1 (en) 2015-12-10
HUE055155T2 (hu) 2021-11-29
US20170071917A1 (en) 2017-03-16
AU2020217342A1 (en) 2020-08-27
US9801864B2 (en) 2017-10-31
US11278529B2 (en) 2022-03-22
US20220016091A1 (en) 2022-01-20
SI3372229T1 (sl) 2021-09-30
US20170087133A1 (en) 2017-03-30
US9446028B2 (en) 2016-09-20
JP2017516868A (ja) 2017-06-22
US20250025448A1 (en) 2025-01-23
PL3372229T3 (pl) 2021-10-04
US20170273956A1 (en) 2017-09-28
JP2021178836A (ja) 2021-11-18
PL3151832T3 (pl) 2021-10-25
US9339495B2 (en) 2016-05-17
AU2024202604A1 (en) 2024-05-09
US20150352085A1 (en) 2015-12-10
US20180015076A1 (en) 2018-01-18
EP3372229A1 (en) 2018-09-12
EP3795156A1 (en) 2021-03-24
JP2020063264A (ja) 2020-04-23
AR100772A1 (es) 2016-11-02
LT3372229T (lt) 2021-07-12
EP3151832B1 (en) 2021-03-24
US20230051859A1 (en) 2023-02-16
CY1124368T1 (el) 2022-07-22
AU2015269667A1 (en) 2016-12-22
SI3151832T1 (sl) 2021-08-31
MX391502B (es) 2025-03-21
IL268960B (en) 2021-05-31
CY1124366T1 (el) 2022-07-22
RS62007B1 (sr) 2021-07-30
MX2016016136A (es) 2017-07-05
HUE055400T2 (hu) 2021-11-29
PT3151832T (pt) 2021-06-15
AU2022200085A1 (en) 2022-02-03
US9744159B2 (en) 2017-08-29
CA2950845C (en) 2023-04-25
DK3151832T3 (da) 2021-06-14
RS62006B1 (sr) 2021-07-30
LT3151832T (lt) 2021-07-12
US20160228418A1 (en) 2016-08-11
ES2876350T3 (es) 2021-11-12
IL249287B (en) 2021-03-25
AU2020217342B2 (en) 2021-10-07
EP3372229B1 (en) 2021-03-24
JP2023123442A (ja) 2023-09-05
WO2015187851A1 (en) 2015-12-10
EP3151832A1 (en) 2017-04-12
IL249287A0 (en) 2017-02-28
MX2020012404A (es) 2022-04-11
US20160038469A1 (en) 2016-02-11
IL268960A (en) 2019-10-31
AU2015269667B2 (en) 2020-07-30
HRP20210901T1 (hr) 2021-09-17

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