ES2841330T3 - Sensor electroquímico y mantenimiento de la función del eléctrico durante la fabricación con una capa protectora - Google Patents
Sensor electroquímico y mantenimiento de la función del eléctrico durante la fabricación con una capa protectora Download PDFInfo
- Publication number
- ES2841330T3 ES2841330T3 ES14773045T ES14773045T ES2841330T3 ES 2841330 T3 ES2841330 T3 ES 2841330T3 ES 14773045 T ES14773045 T ES 14773045T ES 14773045 T ES14773045 T ES 14773045T ES 2841330 T3 ES2841330 T3 ES 2841330T3
- Authority
- ES
- Spain
- Prior art keywords
- electrode
- test sensor
- base
- layer
- priming
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
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- 238000012423 maintenance Methods 0.000 title description 2
- 238000012360 testing method Methods 0.000 claims abstract description 111
- 230000037452 priming Effects 0.000 claims abstract description 97
- 239000010410 layer Substances 0.000 claims abstract description 73
- 239000011241 protective layer Substances 0.000 claims abstract description 58
- 239000012530 fluid Substances 0.000 claims abstract description 28
- 230000002093 peripheral effect Effects 0.000 claims abstract description 17
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 16
- 239000012491 analyte Substances 0.000 claims abstract description 13
- 108090000790 Enzymes Proteins 0.000 claims abstract description 9
- 102000004190 Enzymes Human genes 0.000 claims abstract description 9
- 238000000840 electrochemical analysis Methods 0.000 claims abstract description 8
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- 125000006850 spacer group Chemical group 0.000 claims description 38
- 238000000034 method Methods 0.000 claims description 30
- 229920000642 polymer Polymers 0.000 claims description 16
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- 238000011109 contamination Methods 0.000 claims description 9
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 claims description 8
- 238000003698 laser cutting Methods 0.000 claims description 8
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims description 8
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 6
- 229910052737 gold Inorganic materials 0.000 claims description 6
- 239000010931 gold Substances 0.000 claims description 6
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 5
- 229910052799 carbon Inorganic materials 0.000 claims description 4
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- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 8
- 239000008103 glucose Substances 0.000 description 8
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- 108010015776 Glucose oxidase Proteins 0.000 description 2
- 239000004366 Glucose oxidase Substances 0.000 description 2
- KJTLSVCANCCWHF-UHFFFAOYSA-N Ruthenium Chemical compound [Ru] KJTLSVCANCCWHF-UHFFFAOYSA-N 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
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- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
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- 239000010948 rhodium Substances 0.000 description 2
- MHOVAHRLVXNVSD-UHFFFAOYSA-N rhodium atom Chemical compound [Rh] MHOVAHRLVXNVSD-UHFFFAOYSA-N 0.000 description 2
- 229910052707 ruthenium Inorganic materials 0.000 description 2
- 238000001179 sorption measurement Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000012800 visualization Methods 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- 108010050375 Glucose 1-Dehydrogenase Proteins 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 239000004642 Polyimide Substances 0.000 description 1
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- 238000005299 abrasion Methods 0.000 description 1
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- 230000003466 anti-cipated effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
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- 229910052741 iridium Inorganic materials 0.000 description 1
- GKOZUEZYRPOHIO-UHFFFAOYSA-N iridium atom Chemical compound [Ir] GKOZUEZYRPOHIO-UHFFFAOYSA-N 0.000 description 1
- 238000001540 jet deposition Methods 0.000 description 1
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- 238000012986 modification Methods 0.000 description 1
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- 229920000515 polycarbonate Polymers 0.000 description 1
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- 229920001721 polyimide Polymers 0.000 description 1
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- 239000000276 potassium ferrocyanide Substances 0.000 description 1
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- XOGGUFAVLNCTRS-UHFFFAOYSA-N tetrapotassium;iron(2+);hexacyanide Chemical compound [K+].[K+].[K+].[K+].[Fe+2].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-] XOGGUFAVLNCTRS-UHFFFAOYSA-N 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C28/00—Coating for obtaining at least two superposed coatings either by methods not provided for in a single one of groups C23C2/00 - C23C26/00 or by combinations of methods provided for in subclasses C23C and C25C or C25D
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49002—Electrical device making
- Y10T29/49117—Conductor or circuit manufacturing
- Y10T29/49204—Contact or terminal manufacturing
- Y10T29/49224—Contact or terminal manufacturing with coating
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Electrochemistry (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Heart & Thoracic Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Surgery (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Materials Engineering (AREA)
- Mechanical Engineering (AREA)
- Metallurgy (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/829,447 US9097659B2 (en) | 2013-03-14 | 2013-03-14 | Maintaining electrode function during manufacture with a protective layer |
| PCT/US2014/021845 WO2014159072A1 (en) | 2013-03-14 | 2014-03-07 | Maintaining electrode function during manufacture with a protective layer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2841330T3 true ES2841330T3 (es) | 2021-07-08 |
Family
ID=51522603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14773045T Active ES2841330T3 (es) | 2013-03-14 | 2014-03-07 | Sensor electroquímico y mantenimiento de la función del eléctrico durante la fabricación con una capa protectora |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9097659B2 (enExample) |
| EP (1) | EP2972266B1 (enExample) |
| JP (2) | JP6898096B2 (enExample) |
| CN (1) | CN105122048B (enExample) |
| CA (1) | CA2905740C (enExample) |
| ES (1) | ES2841330T3 (enExample) |
| WO (1) | WO2014159072A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106226379A (zh) * | 2016-07-10 | 2016-12-14 | 浙江亿联健医疗器械有限公司 | 一种消除进样过程影响的生物传感器及测试方法 |
| EP4116705A1 (en) * | 2021-07-05 | 2023-01-11 | ARKRAY, Inc. | Biosensor |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6656702B1 (en) * | 1998-07-03 | 2003-12-02 | Matsushita Electric Industrial Co., Ltd. | Biosensor containing glucose dehydrogenase |
| US6258229B1 (en) * | 1999-06-02 | 2001-07-10 | Handani Winarta | Disposable sub-microliter volume sensor and method of making |
| CA2305922C (en) | 1999-08-02 | 2005-09-20 | Bayer Corporation | Improved electrochemical sensor design |
| AU6459900A (en) | 1999-08-14 | 2001-03-13 | Iit Limited | Analytical apparatus and method |
| US6616819B1 (en) | 1999-11-04 | 2003-09-09 | Therasense, Inc. | Small volume in vitro analyte sensor and methods |
| EP2151683A3 (en) * | 1999-11-15 | 2010-07-28 | Panasonic Corporation | Biosensor, thin film electrode forming method, quantification apparatus, and quantification method |
| GB0005564D0 (en) * | 2000-03-08 | 2000-05-03 | Inverness Medical Ltd | Measurjement of substances in liquid |
| DE10032042A1 (de) | 2000-07-05 | 2002-01-24 | Inventus Biotec Gesellschaft Fuer Innovative Bioanalytik, Biosensoren Und Diagnostika Mbh & Co. Kg | Elektrochemischer Einwegbiosensor für die quantitative Bestimmung von Analytkonzentrationen in Flüssigkeiten |
| US6666821B2 (en) | 2001-01-08 | 2003-12-23 | Medtronic, Inc. | Sensor system |
| AU784254B2 (en) | 2001-05-21 | 2006-03-02 | Bayer Corporation | Improved electrochemical sensor |
| US7132041B2 (en) * | 2003-02-11 | 2006-11-07 | Bayer Healthcare Llc | Methods of determining the concentration of an analyte in a fluid test sample |
| ES2675787T3 (es) * | 2003-06-20 | 2018-07-12 | F. Hoffmann-La Roche Ag | Método y reactivo para producir tiras reactivas estrechas y homogéneas |
| EP2579031B1 (en) * | 2003-12-04 | 2017-09-27 | Panasonic Healthcare Holdings Co., Ltd. | Biosensor for measuring blood component and hematocrit. |
| WO2005103669A1 (ja) * | 2004-04-19 | 2005-11-03 | Matsushita Electric Industrial Co., Ltd. | 血液成分の測定方法、それに用いるバイオセンサおよび測定装置 |
| WO2006027703A2 (en) | 2004-09-09 | 2006-03-16 | Albatros Technologies Gmbh & Co. Kg | Analyte detecting member with a hydrogel |
| BRPI0607841A2 (pt) * | 2005-03-04 | 2009-06-13 | Bayer Healthcare Llc | estabilização da atividade de glicose desidrogenase dependente de pqq em biosensores eletroquìmicos |
| US7846311B2 (en) * | 2005-09-27 | 2010-12-07 | Abbott Diabetes Care Inc. | In vitro analyte sensor and methods of use |
| JP4942763B2 (ja) * | 2005-12-27 | 2012-05-30 | バイエル・ヘルスケア・エルエルシー | 多層試験センサを形成する方法 |
| US7966859B2 (en) | 2006-05-03 | 2011-06-28 | Bayer Healthcare Llc | Underfill detection system for a biosensor |
| WO2007133457A2 (en) * | 2006-05-08 | 2007-11-22 | Bayer Healthcare Llc | Electrochemical test sensor with reduced sample volume |
| ES2748685T3 (es) | 2006-09-22 | 2020-03-17 | Ascensia Diabetes Care Holdings Ag | Sistema de biosensor que tiene estabilidad y rendimiento de hematocrito potenciados |
| US7797987B2 (en) * | 2006-10-11 | 2010-09-21 | Bayer Healthcare Llc | Test sensor with a side vent and method of making the same |
| JP4814953B2 (ja) * | 2006-10-19 | 2011-11-16 | パナソニック株式会社 | 血液試料のヘマトクリット値の測定方法、血液試料中の分析物の濃度の測定方法、センサチップおよびセンサユニット |
| US7749766B2 (en) * | 2007-01-12 | 2010-07-06 | Nova Biomedical Corporation | Bilirubin sensor |
| KR20080076434A (ko) | 2007-02-16 | 2008-08-20 | 박정철 | 생체정보 측정 장치 및 그 제조방법 |
| US20080248581A1 (en) * | 2007-04-06 | 2008-10-09 | Bayer Healthcare Llc | Method for performing correction of blood glucose assay bias using blood hemoglobin concentration |
| WO2009046161A1 (en) * | 2007-10-05 | 2009-04-09 | Bayer Healthcare Llc | Method of defining electrodes using laser-ablation and dielectric material |
| JP5583594B2 (ja) * | 2007-12-10 | 2014-09-03 | バイエル・ヘルスケア・エルエルシー | 試験センサ内に試薬物質を被着させる方法 |
| US8262874B2 (en) * | 2008-04-14 | 2012-09-11 | Abbott Diabetes Care Inc. | Biosensor coating composition and methods thereof |
| JP5262323B2 (ja) | 2008-06-11 | 2013-08-14 | ソニー株式会社 | 多孔性保護膜付き負極、及び多孔性保護膜付き負極の製造方法 |
| US20110137143A1 (en) * | 2008-08-01 | 2011-06-09 | Lightnix, Inc. | Sensor with fine needle having channel formed therein |
| US20110048972A1 (en) * | 2009-08-31 | 2011-03-03 | Lifescan Scotland Limited | Multi-analyte test strip with shared counter/reference electrode and inline electrode configuration |
-
2013
- 2013-03-14 US US13/829,447 patent/US9097659B2/en active Active
-
2014
- 2014-03-07 EP EP14773045.1A patent/EP2972266B1/en active Active
- 2014-03-07 CA CA2905740A patent/CA2905740C/en not_active Expired - Fee Related
- 2014-03-07 WO PCT/US2014/021845 patent/WO2014159072A1/en not_active Ceased
- 2014-03-07 JP JP2016500862A patent/JP6898096B2/ja active Active
- 2014-03-07 CN CN201480022063.5A patent/CN105122048B/zh active Active
- 2014-03-07 ES ES14773045T patent/ES2841330T3/es active Active
-
2019
- 2019-11-01 JP JP2019199934A patent/JP7002514B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016510901A (ja) | 2016-04-11 |
| CN105122048A (zh) | 2015-12-02 |
| CA2905740A1 (en) | 2014-10-02 |
| HK1218327A1 (zh) | 2017-02-10 |
| EP2972266A1 (en) | 2016-01-20 |
| US9097659B2 (en) | 2015-08-04 |
| EP2972266A4 (en) | 2017-01-04 |
| JP7002514B2 (ja) | 2022-01-20 |
| EP2972266B1 (en) | 2020-12-09 |
| JP6898096B2 (ja) | 2021-07-07 |
| CN105122048B (zh) | 2018-01-09 |
| JP2020024221A (ja) | 2020-02-13 |
| WO2014159072A1 (en) | 2014-10-02 |
| US20140262772A1 (en) | 2014-09-18 |
| CA2905740C (en) | 2021-01-19 |
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