JP6898096B2 - 保護層を用いた製造中における電極機能の維持 - Google Patents
保護層を用いた製造中における電極機能の維持 Download PDFInfo
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Description
本出願は、2013年3月14日に出願された米国特許出願第13/829,447号の継続であり、それの開示は、参照により本明細書にこれによって組み込まれる。
4 スペーサ
5 導電材料
6 毛細管チャンネル
8 蓋
9 開口
10 作用電極
12 対向電極
14 トリガ電極
16 反応層
18 保護層
20 導電性リード線
22 導電材料の層
100 試験センサ
102 ベース
102A ベースの縁部
104 スペーサ
104A スペーサの縁部
106 毛細管チャンネル
108 蓋
109 開口
110 作用電極
112 対向電極
114 トリガ電極
115 開口の第1の縁部
115A 第1の縁部分
115B 第2の縁部分
116 反応層
117 第1の開口
118 保護層
118A 保護層の縁部
122 導電層
126 スペーサチャンネル
126A 開放端
127 スペーサの上縁部
128 開口
128A 開口の第1の縁部
130 オーバーハング部分
180 試験センサの外形線
200 試験センサ
Claims (25)
- 流体試料の中の分析物の濃度を検出するための電気化学的試験センサであって、
上面、底面、および前記上面と前記底面との間に延びる周縁部を有する非導電性のベースと、
前記非導電性のベースの上に位置するトリガ電極、作用電極、および対向電極であって、前記トリガ電極が前記ベースの前記周縁部に隣接すると共に前記対向電極に電気的に並列に接続されている、トリガ電極、作用電極、および対向電極と、
前記トリガ電極の少なくとも一部分の上に位置する保護層と、
前記作用電極の少なくとも表面上の反応層であって、前記作用電極に移送される電子を生成するように前記分析物と反応するための酵素を含む反応層と、
前記ベースの上に位置する蓋であって、前記蓋は、上面、底面、および前記上面と前記底面との間に延びる外縁部を有し、前記外縁部は、前記ベースの前記周縁部を越えて延びる、蓋とを備え、
前記トリガ電極、前記作用電極、および前記対向電極以外の電極を含まず、
第1の導電性リード線または配線の先端は前記蓋を超えて前記作用電極から延在しており、第2の導電性リード線または配線の先端は前記蓋を超えて前記トリガ電極および前記対向電極から延在している電気化学的試験センサ。 - 前記保護層は、前記流体試料と接触すると溶解できる、請求項1に記載の試験センサ。
- 前記保護層は、ポリマー層から成る、請求項1に記載の試験センサ。
- 前記ポリマー層は、カルボキシメチルセルロースまたはヒドロキシエチルセルロースを含む、請求項3に記載の試験センサ。
- 前記保護層はさらに、ぬれ性または加工性の向上のための界面活性剤またはレオロジー添加剤を備える、請求項2に記載の試験センサ。
- 前記ベースは、導電層を積層され、印刷され、コートされまたはスパッタされ、前記作用電極、前記トリガ電極、および前記対向電極の各々は、前記導電層からパターン化される、請求項1に記載の試験センサ。
- 前記導電層は、金属層から成る、請求項6に記載の試験センサ。
- 前記導電層は、炭素またはグラファイトから成る、請求項6に記載の試験センサ。
- 前記ベースの上に位置するスペーサをさらに備える、請求項1に記載の試験センサ。
- 前記スペーサは、それを通って延びるチャンネルを有し、前記チャンネルは、前記作用電極および前記トリガ電極と位置合わせされる、請求項9に記載の試験センサ。
- 前記スペーサは、前記反応層と前記蓋との間に位置決めされる、請求項9に記載の試験センサ。
- 流体試料中の分析物の濃度を検出するための電気化学的試験センサを製造する方法において、
ベースの上に位置する導電層から複数の電極をパターン化するステップであって、前記複数の電極は、トリガ電極、作用電極、および対向電極からなり、ステップと、
前記トリガ電極の上に位置する保護層を堆積させるステップと、
前記作用電極の上に位置する反応層を堆積させるステップと、
前記ベースと蓋との間にスペーサを位置決めするステップと、
前記スペーサおよび前記ベースを通って延びる第1の開口を形成するステップと、
前記蓋に第2の開口を形成するステップであって、前記第1の開口および前記第2の開口は、2つの別個のステップで形成される、ステップと、
試験センサを切り取るステップと、を含み、
前記トリガ電極、前記作用電極、および前記対向電極以外の電極を含まず、
前記トリガ電極は前記対向電極に電気的に並列に接続されており、
第1の導電性リード線または配線の先端は前記蓋を超えて前記作用電極から延在しており、第2の導電性リード線または配線の先端は前記蓋を超えて前記トリガ電極および前記対向電極から延在している方法。 - 前記第1の開口は、内側周縁部を有し、前記第2の開口は、内側周縁部を有し、前記第2の開口の前記内側周縁部の少なくとも一部分は、オーバーハングを形成するように、前記第1の開口の前記内側周縁部を越えて延びる、請求項12に記載の方法。
- 保護層を設ける前記ステップは、ポリマー溶液を用いてポリマー層を設けるステップを含む、請求項12に記載の方法。
- 前記ポリマー溶液は、0.25%から1.0%の間の範囲の濃度を有する、請求項14に記載の方法。
- 前記ポリマー溶液の前記濃度は、0.25%である、請求項14に記載の方法。
- 前記ポリマー溶液の前記濃度は、1.0%である、請求項14に記載の方法。
- ポリマー層を適用する前記ステップは、カルボキシメチルセルロースまたはヒドロキシエチルセルロースの層を適用するステップを含む、請求項14に記載の方法。
- パターン化する前記ステップは、電極パターンを形成するように、レーザーを用いて前記導電層の少なくとも一部分を通ってアブレーションするステップを含む、請求項12に記載の方法。
- 前記ベースの上に位置する金、白金、またはパラジウム層を堆積させるステップをさらに含む、請求項12に記載の方法。
- 前記導電層をパターン化する前記ステップはさらに、金、白金、またはパラジウム層をパターン化するステップを含む、請求項20に記載の方法。
- 前記蓋を設けるステップが、前記ベースおよびスペーサを通る開口を設ける前記ステップの後に行われる、請求項12に記載の方法。
- 開口を設ける前記ステップはさらに、開口をレーザー切断するステップを含む、請求項12に記載の方法。
- 前記蓋は、前記開口が位置合わせされるが、前記蓋の縁部が前記トリガ電極の縁部を越えて延びるように、構築され、配置される、請求項12に記載の方法。
- 前記導電層は、可撓性絶縁基板上にある、請求項12に記載の方法。
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PCT/US2014/021845 WO2014159072A1 (en) | 2013-03-14 | 2014-03-07 | Maintaining electrode function during manufacture with a protective layer |
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US9097659B2 (en) | 2015-08-04 |
US20140262772A1 (en) | 2014-09-18 |
ES2841330T3 (es) | 2021-07-08 |
EP2972266A1 (en) | 2016-01-20 |
EP2972266A4 (en) | 2017-01-04 |
CN105122048A (zh) | 2015-12-02 |
JP2016510901A (ja) | 2016-04-11 |
CA2905740C (en) | 2021-01-19 |
JP7002514B2 (ja) | 2022-01-20 |
CN105122048B (zh) | 2018-01-09 |
JP2020024221A (ja) | 2020-02-13 |
CA2905740A1 (en) | 2014-10-02 |
WO2014159072A1 (en) | 2014-10-02 |
HK1218327A1 (zh) | 2017-02-10 |
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