CN105122048B - 在制造期间用保护层维持电极功能 - Google Patents

在制造期间用保护层维持电极功能 Download PDF

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Publication number
CN105122048B
CN105122048B CN201480022063.5A CN201480022063A CN105122048B CN 105122048 B CN105122048 B CN 105122048B CN 201480022063 A CN201480022063 A CN 201480022063A CN 105122048 B CN105122048 B CN 105122048B
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CN
China
Prior art keywords
test sensor
electrode
layer
base
protective layer
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CN201480022063.5A
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English (en)
Chinese (zh)
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CN105122048A (zh
Inventor
安德鲁·艾德布洛克
史蒂芬·C·查尔顿
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Bayer Healthcare LLC
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Bayer Healthcare LLC
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C28/00—Coating for obtaining at least two superposed coatings either by methods not provided for in a single one of groups C23C2/00 - C23C26/00 or by combinations of methods provided for in subclasses C23C and C25C or C25D
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49002—Electrical device making
    • Y10T29/49117—Conductor or circuit manufacturing
    • Y10T29/49204—Contact or terminal manufacturing
    • Y10T29/49224—Contact or terminal manufacturing with coating

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Electrochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Mechanical Engineering (AREA)
  • Metallurgy (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201480022063.5A 2013-03-14 2014-03-07 在制造期间用保护层维持电极功能 Active CN105122048B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/829,447 US9097659B2 (en) 2013-03-14 2013-03-14 Maintaining electrode function during manufacture with a protective layer
US13/829,447 2013-03-14
PCT/US2014/021845 WO2014159072A1 (en) 2013-03-14 2014-03-07 Maintaining electrode function during manufacture with a protective layer

Publications (2)

Publication Number Publication Date
CN105122048A CN105122048A (zh) 2015-12-02
CN105122048B true CN105122048B (zh) 2018-01-09

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480022063.5A Active CN105122048B (zh) 2013-03-14 2014-03-07 在制造期间用保护层维持电极功能

Country Status (7)

Country Link
US (1) US9097659B2 (enExample)
EP (1) EP2972266B1 (enExample)
JP (2) JP6898096B2 (enExample)
CN (1) CN105122048B (enExample)
CA (1) CA2905740C (enExample)
ES (1) ES2841330T3 (enExample)
WO (1) WO2014159072A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106226379A (zh) * 2016-07-10 2016-12-14 浙江亿联健医疗器械有限公司 一种消除进样过程影响的生物传感器及测试方法
EP4116705A1 (en) * 2021-07-05 2023-01-11 ARKRAY, Inc. Biosensor

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101410218A (zh) * 2005-12-27 2009-04-15 拜尔保健有限公司 一种形成多层测试传感器的方法
CN101529237A (zh) * 2006-10-19 2009-09-09 松下电器产业株式会社 血样的血细胞比容值的测定方法、血样中的分析物的浓度的测定方法、传感器芯片以及传感器单元
CN102016060A (zh) * 2008-04-14 2011-04-13 艾伯特糖尿病护理公司 生物传感器涂层组合物及其方法
CN102121915A (zh) * 2009-08-31 2011-07-13 生命扫描苏格兰有限公司 具有共用的对/参考电极和直列电极构型的多分析物测试条

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6656702B1 (en) * 1998-07-03 2003-12-02 Matsushita Electric Industrial Co., Ltd. Biosensor containing glucose dehydrogenase
US6258229B1 (en) * 1999-06-02 2001-07-10 Handani Winarta Disposable sub-microliter volume sensor and method of making
CA2305922C (en) 1999-08-02 2005-09-20 Bayer Corporation Improved electrochemical sensor design
WO2001013103A1 (en) 1999-08-14 2001-02-22 Iit Limited Analytical apparatus and method
US6616819B1 (en) 1999-11-04 2003-09-09 Therasense, Inc. Small volume in vitro analyte sensor and methods
WO2001036953A1 (en) * 1999-11-15 2001-05-25 Matsushita Electric Industrial Co., Ltd. Biosensor, method of forming thin-film electrode, and method and apparatus for quantitative determination
US6733655B1 (en) * 2000-03-08 2004-05-11 Oliver W. H. Davies Measurement of substances in liquids
DE10032042A1 (de) 2000-07-05 2002-01-24 Inventus Biotec Gesellschaft Fuer Innovative Bioanalytik, Biosensoren Und Diagnostika Mbh & Co. Kg Elektrochemischer Einwegbiosensor für die quantitative Bestimmung von Analytkonzentrationen in Flüssigkeiten
US6666821B2 (en) 2001-01-08 2003-12-23 Medtronic, Inc. Sensor system
AU784254B2 (en) * 2001-05-21 2006-03-02 Bayer Corporation Improved electrochemical sensor
US7132041B2 (en) * 2003-02-11 2006-11-07 Bayer Healthcare Llc Methods of determining the concentration of an analyte in a fluid test sample
US7727467B2 (en) * 2003-06-20 2010-06-01 Roche Diagnostics Operations, Inc. Reagent stripe for test strip
EP2579031B1 (en) * 2003-12-04 2017-09-27 Panasonic Healthcare Holdings Co., Ltd. Biosensor for measuring blood component and hematocrit.
EP3115777B1 (en) * 2004-04-19 2020-01-08 PHC Holdings Corporation Method for measuring blood components
WO2006027703A2 (en) 2004-09-09 2006-03-16 Albatros Technologies Gmbh & Co. Kg Analyte detecting member with a hydrogel
TW200643173A (en) * 2005-03-04 2006-12-16 Bayer Healthcare Llc Stabilizing enzyme activity in electrochemical biosensors
US7846311B2 (en) * 2005-09-27 2010-12-07 Abbott Diabetes Care Inc. In vitro analyte sensor and methods of use
US7966859B2 (en) 2006-05-03 2011-06-28 Bayer Healthcare Llc Underfill detection system for a biosensor
CA2650949C (en) * 2006-05-08 2018-06-12 Bayer Healthcare Llc Electrochemical test sensor with reduced sample volume
EP3543348B1 (en) 2006-09-22 2020-11-18 Ascensia Diabetes Care Holdings AG Biosensor system having enhanced stability and hematocrit performance
US7797987B2 (en) * 2006-10-11 2010-09-21 Bayer Healthcare Llc Test sensor with a side vent and method of making the same
US7749766B2 (en) * 2007-01-12 2010-07-06 Nova Biomedical Corporation Bilirubin sensor
KR20080076434A (ko) 2007-02-16 2008-08-20 박정철 생체정보 측정 장치 및 그 제조방법
US20080248581A1 (en) * 2007-04-06 2008-10-09 Bayer Healthcare Llc Method for performing correction of blood glucose assay bias using blood hemoglobin concentration
WO2009046161A1 (en) * 2007-10-05 2009-04-09 Bayer Healthcare Llc Method of defining electrodes using laser-ablation and dielectric material
US8609180B2 (en) * 2007-12-10 2013-12-17 Bayer Healthcare Llc Method of depositing reagent material in a test sensor
JP5262323B2 (ja) 2008-06-11 2013-08-14 ソニー株式会社 多孔性保護膜付き負極、及び多孔性保護膜付き負極の製造方法
JPWO2010013598A1 (ja) * 2008-08-01 2012-01-12 株式会社ライトニックス 流路形成微細針付きセンサ

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101410218A (zh) * 2005-12-27 2009-04-15 拜尔保健有限公司 一种形成多层测试传感器的方法
CN101529237A (zh) * 2006-10-19 2009-09-09 松下电器产业株式会社 血样的血细胞比容值的测定方法、血样中的分析物的浓度的测定方法、传感器芯片以及传感器单元
CN102016060A (zh) * 2008-04-14 2011-04-13 艾伯特糖尿病护理公司 生物传感器涂层组合物及其方法
CN102121915A (zh) * 2009-08-31 2011-07-13 生命扫描苏格兰有限公司 具有共用的对/参考电极和直列电极构型的多分析物测试条

Also Published As

Publication number Publication date
US9097659B2 (en) 2015-08-04
WO2014159072A1 (en) 2014-10-02
HK1218327A1 (zh) 2017-02-10
JP6898096B2 (ja) 2021-07-07
EP2972266A1 (en) 2016-01-20
CA2905740A1 (en) 2014-10-02
JP2020024221A (ja) 2020-02-13
ES2841330T3 (es) 2021-07-08
JP7002514B2 (ja) 2022-01-20
EP2972266B1 (en) 2020-12-09
CN105122048A (zh) 2015-12-02
US20140262772A1 (en) 2014-09-18
JP2016510901A (ja) 2016-04-11
EP2972266A4 (en) 2017-01-04
CA2905740C (en) 2021-01-19

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