ES2818929T3 - Péptidos de unión beta amiloide y sus usos para el tratamiento y el diagnóstico de la demencia de Alzheimer - Google Patents
Péptidos de unión beta amiloide y sus usos para el tratamiento y el diagnóstico de la demencia de Alzheimer Download PDFInfo
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- ES2818929T3 ES2818929T3 ES14799955T ES14799955T ES2818929T3 ES 2818929 T3 ES2818929 T3 ES 2818929T3 ES 14799955 T ES14799955 T ES 14799955T ES 14799955 T ES14799955 T ES 14799955T ES 2818929 T3 ES2818929 T3 ES 2818929T3
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Classifications
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
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Applications Claiming Priority (3)
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| DE102014003262.0A DE102014003262A1 (de) | 2014-03-12 | 2014-03-12 | Amyloid-Beta-bindende Peptide und deren Verwendung für die Therapie und die Diagnose der Alzheimerschen Demenz |
| PCT/DE2014/000477 WO2015043567A1 (de) | 2013-09-26 | 2014-09-23 | Amyloid-beta-bindende peptide und deren verwendung für die therapie und die diagnose der alzheimerschen demenz |
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| DE102016125645A1 (de) | 2016-12-23 | 2018-06-28 | Forschungszentrum Jülich GmbH | D-enantiomere Peptide zur Therapie von chronischem und neuropathischem Schmerz |
| CN106866792B (zh) * | 2017-02-24 | 2020-09-04 | 中山大学 | 一类环十肽分子及其应用 |
| DE102017010842A1 (de) * | 2017-11-23 | 2019-05-23 | Forschungszentrum Jülich GmbH | Verfahren zur Quantifizierung von Proteinaggregaten einer Proteinfehlfaltungserkrankung in einer Probe |
| DE102021121435A1 (de) | 2021-08-18 | 2023-02-23 | Priavoid Gmbh | Aß-BINDENDE SUBSTANZEN |
| AU2024325238A1 (en) * | 2023-08-16 | 2026-03-05 | LVIS-Regain LP | Compositions and methods for prophylaxis and/or treatment of amyloid b peptide proteinopenia in alzheimer's and other diseases |
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| EP0815134B1 (en) | 1995-03-14 | 2002-06-05 | Praecis Pharmaceuticals Incorporated | Modulators of amyloid aggregation |
| US7384910B2 (en) * | 1997-10-08 | 2008-06-10 | Castillo Gerardo M | Small peptides for the treatment of Alzheimer's disease and other beta-amyloid protein fibrillogenesis disorders |
| ES2260956T3 (es) | 1998-12-18 | 2006-11-01 | The Penn State Research Foundation | Ciclacion de peptidos mediada por inteina. |
| WO2001034631A2 (en) | 1999-11-05 | 2001-05-17 | Axonyx, Inc. | PEPTIDE ANALOGS AND MIMETICS SUITABLE FOR IN VIVO USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ABNORMAL PROTEIN FOLDING INTO AMYLOID, AMYLOID-LIKE DEPOSITS OR β-SHEET RICH PATHOLOGICAL PRECURSOR THEREOF |
| AU1608801A (en) | 1999-11-15 | 2001-05-30 | Parker Hughes Institute | Diamino platinum (ii) antitumor complexes |
| DE10117281A1 (de) | 2001-04-06 | 2002-10-24 | Inst Molekulare Biotechnologie | Peptid zur Diagnose und Therapie der Alzheimer-Demenz |
| JP5137400B2 (ja) * | 2003-06-30 | 2013-02-06 | テル アヴィヴ ユニヴァーシティ フューチャー テクノロジー ディヴェロップメント エル．ピー． | アミロイド関連疾患を診断および処置するためのペプチド、それに対する抗体、ならびにその使用方法 |
| GB0503434D0 (en) * | 2005-02-18 | 2005-03-30 | Senexis Ltd | Amyloid-binding peptides, analogues and uses thereof |
| DE102005049537B4 (de) | 2005-10-17 | 2010-04-22 | Forschungszentrum Karlsruhe Gmbh | Verfahren zur Herstellung zyklischer Peptide und Verwendung der derart hergestellten zyklischen Peptide |
| DE102006015140A1 (de) | 2006-03-31 | 2007-10-11 | Philipps-Universität Marburg | Heterozyklische Verbindungen mit Wirkung gegen neurodegenerative Erkrankungen |
| WO2007145589A1 (en) * | 2006-06-15 | 2007-12-21 | Per Arvidsson | Peptides that are capable of binding to amyloid-beta peptide. |
| WO2008116293A1 (en) | 2007-03-23 | 2008-10-02 | The Governors Of The University Of Alberta | Multivalent heterobifunctional polymers and methods of their use |
| DE102008037564A1 (de) * | 2008-11-19 | 2010-05-20 | Forschungszentrum Jülich GmbH | Zusammensetzung zur Herstellung von anti-Amyloid beta-Peptid-Antikörpern mit D-Peptiden |
| DE102010019336A1 (de) | 2010-05-05 | 2011-11-10 | Forschungszentrum Jülich GmbH | Mittel zur Behandlung der Alzheimerschen Demenz |
| DE102010017130B4 (de) | 2010-05-28 | 2018-11-29 | Forschungszentrum Jülich GmbH | Hybrid-Verbindung, deren Verwendung und Verfahren zu deren Herstellung |
| WO2013021353A1 (en) | 2011-08-11 | 2013-02-14 | Bar-Ilan University | Surface modified proteinaceous spherical particles and uses thereof |
| DE102012102999A1 (de) | 2012-04-05 | 2013-10-10 | Forschungszentrum Jülich GmbH | Verfahren zur Behandlung von Blut, Blutprodukten und Organen |
| JP6434903B2 (ja) | 2012-04-05 | 2018-12-05 | フォルシュングスツェントルム ユーリッヒ ゲゼルシャフト ミット ベシュレンクテル ハフツングＦｏｒｓｃｈｕｎｇｓｚｅｎｔｒｕｍ Ｊｕｅｌｉｃｈ ＧｍｂＨ | 多価アミロイドβに結合するＤ−ペプチド含有ポリマー及びその使用 |
| CN108926749A (zh) | 2012-04-05 | 2018-12-04 | 于利希研究中心有限公司 | 处理血液、血液产品和器官的方法 |
| DE102012102998B4 (de) | 2012-04-05 | 2013-12-05 | Forschungszentrum Jülich GmbH | Polymere, enthaltend multivalente Amyloid-Beta-bindende D-Peptide und deren Verwendung |
| US10030056B2 (en) | 2013-04-30 | 2018-07-24 | Forschungszentrum Juelich Gmbh | Agents for preventing and treating HIV and other viral infections |
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| US11274125B2 (en) | 2022-03-15 |
| EP3747454B1 (de) | 2023-06-07 |
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| US20160297852A1 (en) | 2016-10-13 |
| CN105745219B (zh) | 2020-10-09 |
| US20200002379A9 (en) | 2020-01-02 |
| EP3049099A1 (de) | 2016-08-03 |
| CN105745219A (zh) | 2016-07-06 |
| JP2016539911A (ja) | 2016-12-22 |
| US10995118B2 (en) | 2021-05-04 |
| DK3049099T3 (da) | 2020-09-21 |
| EP3747454C0 (de) | 2023-06-07 |
| WO2015043567A1 (de) | 2015-04-02 |
| JP6660877B2 (ja) | 2020-03-11 |
| EP3747454A1 (de) | 2020-12-09 |
| US20200317734A1 (en) | 2020-10-08 |
| EP3049099B1 (de) | 2020-06-17 |
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