ES2817888T3 - Inhibidor de galactósido de galectina-3 y su uso para tratar fibrosis pulmonar - Google Patents
Inhibidor de galactósido de galectina-3 y su uso para tratar fibrosis pulmonar Download PDFInfo
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- ES2817888T3 ES2817888T3 ES13785446T ES13785446T ES2817888T3 ES 2817888 T3 ES2817888 T3 ES 2817888T3 ES 13785446 T ES13785446 T ES 13785446T ES 13785446 T ES13785446 T ES 13785446T ES 2817888 T3 ES2817888 T3 ES 2817888T3
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- compound
- galectin
- pulmonary fibrosis
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- lung
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Landscapes
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| US201261720641P | 2012-10-31 | 2012-10-31 | |
| CA2794066A CA2794066C (en) | 2012-10-31 | 2012-10-31 | Galactoside inhibitor of galectins |
| CA2795753A CA2795753A1 (en) | 2012-10-31 | 2012-11-15 | Novel galactoside inhibitor of galectins |
| US13/832,672 US9243021B2 (en) | 2012-10-31 | 2013-03-15 | Galactoside inhibitor of galectins |
| PCT/EP2013/072691 WO2014067986A1 (en) | 2012-10-31 | 2013-10-30 | Galactoside inhibitor of galectin-3 and its use for treating pulmonary fibrosis |
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| EP2620443A1 (en) | 2012-01-25 | 2013-07-31 | Galecto Biotech AB | Novel galactoside inhibitors of galectins |
| EP3415522A1 (en) | 2014-07-09 | 2018-12-19 | Galecto Biotech AB | Novel hybrid galactoside inhibitor of galectins |
| US10464964B2 (en) | 2015-01-16 | 2019-11-05 | Galecto Biotech Ab | Galactoside inhibitor of galectins |
| EP3828191A3 (en) * | 2015-01-30 | 2021-08-18 | Galecto Biotech AB | Novel galactoside inhibitor of galectins |
| ES2834644T3 (es) * | 2015-05-12 | 2021-06-18 | Galecto Biotech Ab | Tratamiento una vez al día de la fibrosis pulmonar |
| JP6915956B2 (ja) * | 2015-05-15 | 2021-08-11 | ガレクト・バイオテック・エイビイ | 肺線維症の１日１回の治療 |
| US10799522B2 (en) * | 2015-07-27 | 2020-10-13 | Wayne State University | Compositions and methods relating to galectin detection |
| CA3000924A1 (en) * | 2015-11-09 | 2017-05-18 | Galecto Biotech Ab | Novel galactoside inhibitors of galectins |
| EP3896075A1 (en) | 2015-12-18 | 2021-10-20 | Galecto Biotech AB | Polymorphic forms and process |
| EP3423461A4 (en) * | 2016-03-04 | 2020-03-25 | Galectin Sciences, LLC | SELENOGALACTOSIDE COMPOUNDS FOR THE PREVENTION AND TREATMENT OF DISEASES ASSOCIATED WITH GALECTIN AND THEIR USE |
| EP3484903A1 (en) | 2016-07-12 | 2019-05-22 | Galecto Biotech AB | Alpha-d-galactoside inhibitors of galectins |
| WO2018011094A1 (en) | 2016-07-12 | 2018-01-18 | Galecto Biotech Ab | Alpha-d-galactoside inhibitors of galectins |
| EP3621973A4 (en) * | 2017-05-12 | 2021-10-27 | Galectin Sciences, LLC | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF DISEASES AND THEIR USE |
| US11267811B2 (en) | 2017-09-27 | 2022-03-08 | Bristol-Myers Squibb Company | Small molecule inhibitors of galectin-3 |
| US11072626B2 (en) | 2017-10-11 | 2021-07-27 | Bristol-Myers Squibb Company | Small molecule inhibitors of Galectin-3 |
| WO2019133878A1 (en) | 2017-12-29 | 2019-07-04 | Glycomimetics, Inc. | Heterobifunctional inhibitors of e-selectin and galectin-3 |
| MX2020007391A (es) | 2018-01-10 | 2020-09-03 | Galecto Biotech Ab | Nuevo galactosido inhibidor de galectinas. |
| CA3100381A1 (en) | 2018-05-17 | 2019-11-21 | Actuate Therapeutics, Inc. | Treatment of idiopathic pulmonary fibrosis with glycogen synthase kinase 3 form beta inhibitors |
| EP3807290B1 (en) * | 2018-06-15 | 2022-03-30 | Bristol-Myers Squibb Company | Tetrahydropyran-based thiodisaccharide mimics as galectin-3 inhibitors |
| CA3102155A1 (en) | 2018-06-29 | 2020-01-02 | Glykos Biomedical Oy | Conjugates |
| CA3114055A1 (en) | 2018-10-15 | 2020-04-23 | Galecto Biotech Ab | Prodrug of galactoside inhibitors of galectins |
| EP3867260A1 (en) | 2018-10-15 | 2021-08-25 | Galecto Biotech AB | Galactoside inhibitor of galectins |
| US11447517B2 (en) | 2018-11-21 | 2022-09-20 | Galecto Biotech Ab | Galactoside inhibitor of galectins |
| CN113166122A (zh) | 2018-12-06 | 2021-07-23 | 百时美施贵宝公司 | 半乳糖凝集素-3的小分子抑制剂 |
| US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
| EP3902797A1 (en) | 2018-12-27 | 2021-11-03 | GlycoMimetics, Inc. | Galectin-3 inhibiting c-glycosides |
| US12275719B2 (en) | 2019-03-26 | 2025-04-15 | Bristol-Myers Squibb Company | Small molecule inhibitors of galectin-3 |
| US12269819B2 (en) | 2019-04-10 | 2025-04-08 | Bristol-Myers Squibb Company | Small molecule inhibitors of Galectin-3 |
| US12291547B2 (en) | 2019-06-14 | 2025-05-06 | UNIVERSITé LAVAL | Synthesis of 3-azido-3-deoxy-D-galactopyranose |
| CA3144551A1 (en) | 2019-06-24 | 2020-12-30 | Galecto Biotech Ab | Large scale process of 3,3'-dideoxy-3,3'-bis-[4-(3-fluorophenyl)-1h-1,2,3-triazol-1-yl]-1,1'-sulfanediyl-di-beta-d-galactopyranoside |
| EP3993870A1 (en) | 2019-07-03 | 2022-05-11 | Galecto Biotech AB | Novel galactoside inhibitor of galectins |
| WO2021001538A1 (en) | 2019-07-03 | 2021-01-07 | Galecto Biotech Ab | Novel galactoside inhibitor of galectins |
| CA3143078A1 (en) | 2019-07-05 | 2021-01-14 | Galecto Biotech Ab | Novel galactoside inhibitor of galectins |
| WO2021028336A1 (en) | 2019-08-09 | 2021-02-18 | Idorsia Pharmaceuticals Ltd | (hetero)aryl-methyl-thio-beta-d-galactopyranoside derivatives |
| JP7612663B2 (ja) | 2019-08-09 | 2025-01-14 | イドルシア・ファーマシューティカルズ・リミテッド | （２－アセタミジル）チオ－ベータ－ｄ－ガラクトピラノシド誘導体 |
| CA3147454A1 (en) | 2019-08-15 | 2021-02-18 | Martin Bolli | 2-hydroxycycloalkane-1-carbamoyl derivatives |
| RS65294B1 (sr) | 2019-08-29 | 2024-04-30 | Idorsia Pharmaceuticals Ltd | Derivati alfa-d-galaktopiranozida |
| WO2021123506A1 (en) | 2019-12-18 | 2021-06-24 | Glykos Biomedical Oy | Stabile conjugate |
| US20230107479A1 (en) * | 2020-03-23 | 2023-04-06 | G3 Pharmaceuticals, Inc. | Methods and compositions for preventing and treating fibrosis resulting from a coronavirus infection |
| JP2023519952A (ja) * | 2020-03-31 | 2023-05-15 | ガレクト バイオテック エービー | １，２，４，６－テトラ－ｏ－アセチル－３－アジド－３－デオキシ－ｄ－ガラクトピラノシドを調製するための大規模方法 |
| JP7705884B2 (ja) | 2020-05-05 | 2025-07-10 | ブリストル－マイヤーズ スクイブ カンパニー | ガレクチン－３の低分子阻害剤 |
| US12286424B2 (en) | 2020-05-11 | 2025-04-29 | Bristol-Myers Squibb Company | Small molecule inhibitors of galectin-3 |
| KR20230018431A (ko) | 2020-05-28 | 2023-02-07 | 브리스톨-마이어스 스큅 컴퍼니 | 갈렉틴-3 억제제 |
| WO2022073969A1 (en) | 2020-10-06 | 2022-04-14 | Idorsia Pharmaceuticals Ltd | Spiro derivatives of alpha-d-galactopyranosides |
| US12291520B2 (en) | 2020-11-02 | 2025-05-06 | Idorsia Pharmaceuticals Ltd | Galectin-3 inhibiting 2-hydroxycycloalkane-1-carbamoyl derivatives |
| US12304902B2 (en) | 2021-02-09 | 2025-05-20 | Idorsia Pharmaceuticals Ltd | Hydroxyheterocycloalkane-carbamoyl derivatives |
| HUE072194T2 (hu) | 2021-03-03 | 2025-10-28 | Idorsia Pharmaceuticals Ltd | Triazolil-metil-szubsztituált alfa-D-galaktopiranozid származékok |
| WO2025111704A1 (en) * | 2023-12-01 | 2025-06-05 | UNIVERSITé LAVAL | Selective inhibitors of galectin-3 |
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| US5152456A (en) | 1989-12-12 | 1992-10-06 | Bespak, Plc | Dispensing apparatus having a perforate outlet member and a vibrating device |
| GB9027234D0 (en) | 1990-12-15 | 1991-02-06 | Harris Pharma Ltd | An inhalation device |
| CA2112674C (en) | 1991-07-02 | 2005-10-04 | John S. Patton | Method and device for delivering aerosolized medicaments |
| EA001237B1 (ru) | 1996-01-03 | 2000-12-25 | Глаксо Груп Лимитед | Ингаляционное устройство |
| DE19726110C2 (de) | 1997-06-20 | 1999-07-22 | Draegerwerk Ag | Aerosolgenerator für Beatmungssysteme |
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| EP1386672B1 (en) | 2002-08-02 | 2010-04-07 | PARI Pharma GmbH | Fluid droplet production apparatus |
| DE10250625A1 (de) | 2002-10-30 | 2004-05-19 | Pari GmbH Spezialisten für effektive Inhalation | Inhalationstherapievorrichtung |
| DE10257381B4 (de) | 2002-12-09 | 2006-09-14 | Pari GmbH Spezialisten für effektive Inhalation | Inhalationstherapievorrichtung |
| SE0401301D0 (sv) | 2004-05-21 | 2004-05-21 | Forskarpatent I Syd Ab | Novel 3-triazolyl-galactoside inhibitors of galectins |
| SE0401300D0 (sv) | 2004-05-21 | 2004-05-21 | Forskarpatent I Syd Ab | Novel Galactoside Inhibitors of Galectins |
| WO2006009209A1 (ja) * | 2004-07-22 | 2006-01-26 | Kaken Pharmaceutical Co., Ltd. | 慢性炎症性肺疾患を予防もしくは治療する薬剤 |
| WO2010126435A1 (en) | 2009-04-28 | 2010-11-04 | Forskarpatent I Syd Ab | Novel galactoside inhibitors of galectins |
| DE102009026636B4 (de) | 2009-06-02 | 2011-04-14 | Pari Pharma Gmbh | Verfahren zum Verschweißen einer Membran mit einem Träger bei der Herstellung eines Membranverneblers |
| JP6031510B2 (ja) * | 2011-04-12 | 2016-11-24 | モイライ マトリックス インコーポレイテッド | 異常な線維芽細胞増殖及び細胞外マトリックスの沈着を特徴とする疾患、症状又はプロセスを予防又は治療する組成物及び方法 |
-
2013
- 2013-10-30 ES ES13785446T patent/ES2817888T3/es active Active
- 2013-10-30 EP EP13785446.9A patent/EP2914269B1/en active Active
- 2013-10-30 EP EP17183955.8A patent/EP3278805A1/en not_active Withdrawn
- 2013-10-30 CN CN201380057194.2A patent/CN104755088A/zh active Pending
- 2013-10-30 JP JP2015538502A patent/JP2015535233A/ja active Pending
- 2013-10-30 WO PCT/EP2013/072691 patent/WO2014067986A1/en not_active Ceased
- 2013-10-30 IN IN2573DEN2015 patent/IN2015DN02573A/en unknown
- 2013-10-30 CA CA2884802A patent/CA2884802A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN104755088A (zh) | 2015-07-01 |
| EP2914269B1 (en) | 2020-07-29 |
| IN2015DN02573A (enExample) | 2015-09-11 |
| JP2015535233A (ja) | 2015-12-10 |
| WO2014067986A8 (en) | 2016-04-14 |
| EP3278805A1 (en) | 2018-02-07 |
| CA2884802A1 (en) | 2014-05-08 |
| EP2914269A1 (en) | 2015-09-09 |
| WO2014067986A1 (en) | 2014-05-08 |
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