ES2774217T3 - Un péptido biomimético y una plataforma de administración biodegradable para el tratamiento de enfermedades dependientes de angiogénesis y linfangiogénesis - Google Patents
Un péptido biomimético y una plataforma de administración biodegradable para el tratamiento de enfermedades dependientes de angiogénesis y linfangiogénesis Download PDFInfo
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- ES2774217T3 ES2774217T3 ES14807179T ES14807179T ES2774217T3 ES 2774217 T3 ES2774217 T3 ES 2774217T3 ES 14807179 T ES14807179 T ES 14807179T ES 14807179 T ES14807179 T ES 14807179T ES 2774217 T3 ES2774217 T3 ES 2774217T3
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| PCT/US2014/041526 WO2014197892A1 (en) | 2013-06-07 | 2014-06-09 | A biomimetic peptide and biodegradable delivery platform for the treatment of angiogenesis- and lymphangiogenesis-dependent diseases |
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| WO2016022947A1 (en) | 2014-08-07 | 2016-02-11 | The Johns Hopkins University | Nanoparticle modification of human adipose-derived mesenchymal stem cells for treating brain cancer and other neurological diseases |
| KR101748120B1 (ko) * | 2015-07-13 | 2017-06-16 | 서울대학교산학협력단 | 나노입자-유리체 기반 단백질 복합체를 유효성분으로 포함하는 혈관신생억제용 조성물 및 이의 용도 |
| EP3377080B1 (en) | 2015-11-19 | 2024-02-14 | Asclepix Therapeutics, LLC | Peptides with anti-angiogenic, anti-lymphangiogenic, and anti-edemic properties and nanoparticle formulations |
| WO2018067646A1 (en) * | 2016-10-04 | 2018-04-12 | Asclepix Therapeutics, Llc | Compounds and methods for activating tie2 signaling |
| CA3063140A1 (en) * | 2017-05-08 | 2018-11-15 | Asclepix Therapeutics, Inc. | Biodegradable microparticles for sustained delivery of anti-angiogenic peptide |
| US11674959B2 (en) | 2017-08-03 | 2023-06-13 | The Johns Hopkins University | Methods for identifying and preparing pharmaceutical agents for activating Tie1 and/or Tie2 receptors |
| WO2019075056A1 (en) | 2017-10-10 | 2019-04-18 | The Johns Hopkins University | BIODEGRADABLE BIOMIMETIC PARTICLES |
| US11697804B2 (en) | 2018-10-01 | 2023-07-11 | The Johns Hopkins University | Transcriptionally targeted and CpG-free plasmid for theranostic gene therapy |
| WO2020163601A2 (en) * | 2019-02-06 | 2020-08-13 | The University Of North Carolina At Chapel Hill | Compositions and methods for inhibiting post-surgical adhesions |
| CA3134816A1 (en) * | 2019-03-26 | 2020-10-01 | Asclepix Therapeutics, Inc. | Compositions and methods for treating ocular disease |
| US12605463B2 (en) | 2019-04-12 | 2026-04-21 | The Johns Hopkins University | Tolerogenic artificial antigen-presenting cells |
| CN113144213B (zh) * | 2021-03-23 | 2023-04-07 | 西安交通大学医学院第一附属医院 | 一种多级pH响应基因-药物共递送的纳米药物、制备方法及其应用 |
| WO2024044745A2 (en) * | 2022-08-26 | 2024-02-29 | Asclepix Therapeutics, Inc. | Formulations for intraocular delivery of peptides derived from type iv collagen |
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| WO2007120368A2 (en) * | 2006-01-09 | 2007-10-25 | The Regents Of The University Of California | Immunostimulatory combinations for vaccine adjuvants |
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| CA2666709A1 (en) * | 2006-11-10 | 2008-05-29 | Genentech, Inc. | Method for treating age-related macular degeneration |
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| WO2009135854A2 (en) * | 2008-05-06 | 2009-11-12 | Glaxo Group Limited | Encapsulation of biologically active agents |
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| US9717694B2 (en) * | 2009-05-15 | 2017-08-01 | The Johns Hopkins University | Peptide/particle delivery systems |
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| US20120270770A1 (en) * | 2010-08-03 | 2012-10-25 | Jesse Michael Jaynes | Anti-angiogenic peptides and their uses |
| WO2012079088A2 (en) | 2010-12-10 | 2012-06-14 | The Johns Hopkins University | Mimetic peptides derived from collagen type iv and their use for treating angiogenesis- and lymphangiogenesis- dependent diseases |
| JP5747312B2 (ja) | 2011-02-24 | 2015-07-15 | コニカミノルタ株式会社 | 活性光線硬化型インクジェットインク及び画像形成方法 |
| US20150272900A1 (en) | 2012-10-26 | 2015-10-01 | The Johns Hopkins University | Layer-By-Layer Approach to Co-Deliver DNA and siRNA via AuNPs: A Potential Platform for Modifying Release Kinetics |
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| EP3003343B1 (en) | 2019-10-23 |
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| US20240391957A1 (en) | 2024-11-28 |
| HUE047735T2 (hu) | 2020-05-28 |
| US9802984B2 (en) | 2017-10-31 |
| JP6470740B2 (ja) | 2019-02-13 |
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