HK1222542A1 - 用於治療血管生成依賴性和淋巴管生成依賴性疾病的生物模擬肽和生物可降解的遞送平臺 - Google Patents
用於治療血管生成依賴性和淋巴管生成依賴性疾病的生物模擬肽和生物可降解的遞送平臺Info
- Publication number
- HK1222542A1 HK1222542A1 HK16110656.6A HK16110656A HK1222542A1 HK 1222542 A1 HK1222542 A1 HK 1222542A1 HK 16110656 A HK16110656 A HK 16110656A HK 1222542 A1 HK1222542 A1 HK 1222542A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- lymphangiogenesis
- angiogenesis
- treatment
- delivery platform
- dependent diseases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Nanotechnology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Transplantation (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361832290P | 2013-06-07 | 2013-06-07 | |
| PCT/US2014/041526 WO2014197892A1 (en) | 2013-06-07 | 2014-06-09 | A biomimetic peptide and biodegradable delivery platform for the treatment of angiogenesis- and lymphangiogenesis-dependent diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1222542A1 true HK1222542A1 (zh) | 2017-07-07 |
Family
ID=52008639
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16110656.6A HK1222542A1 (zh) | 2013-06-07 | 2016-09-07 | 用於治療血管生成依賴性和淋巴管生成依賴性疾病的生物模擬肽和生物可降解的遞送平臺 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US9802984B2 (zh) |
| EP (2) | EP3003343B1 (zh) |
| JP (2) | JP6470740B2 (zh) |
| CN (2) | CN110981941A (zh) |
| AU (1) | AU2014274703B2 (zh) |
| CA (1) | CA2914764C (zh) |
| DK (1) | DK3003343T3 (zh) |
| ES (1) | ES2774217T3 (zh) |
| HK (1) | HK1222542A1 (zh) |
| HU (1) | HUE047735T2 (zh) |
| IL (1) | IL242760B (zh) |
| WO (1) | WO2014197892A1 (zh) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE047735T2 (hu) * | 2013-06-07 | 2020-05-28 | Univ Johns Hopkins | Egy biometrikus peptid és biológiailag lebomló szállító rendszer az angiogenesis- és lymphangiogenesis függõ betegségek kezelésében |
| WO2016022947A1 (en) | 2014-08-07 | 2016-02-11 | The Johns Hopkins University | Nanoparticle modification of human adipose-derived mesenchymal stem cells for treating brain cancer and other neurological diseases |
| KR101748120B1 (ko) * | 2015-07-13 | 2017-06-16 | 서울대학교산학협력단 | 나노입자-유리체 기반 단백질 복합체를 유효성분으로 포함하는 혈관신생억제용 조성물 및 이의 용도 |
| SG10202004259PA (en) * | 2015-11-19 | 2020-06-29 | Asclepix Therapeutics Llc | Peptides with anti-angiogenic, anti-lymphangiogenic, and anti-edemic properties and nanoparticle formulations |
| BR112019006735A2 (pt) * | 2016-10-04 | 2019-06-25 | Asclepix Therapeutics Llc | compostos e métodos para ativação da sinalização de tie2 |
| KR20200003859A (ko) * | 2017-05-08 | 2020-01-10 | 아스클리픽스 테라퓨틱스, 인크. | 항-혈관신생 펩티드의 지속적인 운반을 위한 생물분해가능한 미립자 |
| WO2019028427A1 (en) * | 2017-08-03 | 2019-02-07 | Asclepix Therapeutics, Llc. | METHODS OF IDENTIFYING AND PREPARING PHARMACEUTICAL AGENTS TO ACTIVATE TIE2 RECEPTOR |
| US11697804B2 (en) | 2018-10-01 | 2023-07-11 | The Johns Hopkins University | Transcriptionally targeted and CpG-free plasmid for theranostic gene therapy |
| JP2022527276A (ja) * | 2019-03-26 | 2022-06-01 | アスクレピクス セラピューティクス インコーポレイテッド | 眼疾患を治療するための組成物及び方法 |
| CN113144213B (zh) * | 2021-03-23 | 2023-04-07 | 西安交通大学医学院第一附属医院 | 一种多级pH响应基因-药物共递送的纳米药物、制备方法及其应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2015781A4 (en) | 2005-09-12 | 2009-12-23 | Univ Johns Hopkins | COMPOSITIONS HAVING ANTIANGIOGENIC ACTIVITY AND USES THEREOF |
| US20090081157A1 (en) * | 2006-01-09 | 2009-03-26 | Richard Syd Kornbluth | Immunostimulatory Combinations for Vaccine Adjuvants |
| ITMI20060625A1 (it) * | 2006-03-31 | 2007-10-01 | Istituto Naz Per La Ricerca | Peptide antiangiogenico e suoi impieghi terapeutici |
| JP2010509369A (ja) * | 2006-11-10 | 2010-03-25 | ジェネンテック インコーポレイテッド | 加齢黄斑変性症を処置するための方法 |
| US8507434B2 (en) * | 2007-01-03 | 2013-08-13 | The Johns Hopkins University | Peptide modulators of angiogenesis and use thereof |
| BRPI0912536A2 (pt) * | 2008-05-06 | 2018-10-16 | Glaxo Group Ltd | método para produzir um carregador particulado, carreador particulado, composição farmacêutica, e, e uso da mesma. |
| EP2315775A2 (en) | 2008-07-21 | 2011-05-04 | Compugen Ltd. | Angiopoietin derived peptides |
| US9717694B2 (en) * | 2009-05-15 | 2017-08-01 | The Johns Hopkins University | Peptide/particle delivery systems |
| WO2011084620A2 (en) | 2009-12-16 | 2011-07-14 | Brigham And Women's Hospital, Inc. | Particles for multiple agent delivery |
| US20120192339A1 (en) | 2010-07-28 | 2012-08-02 | Honeywell International Inc. | Flexible Body Armor Vest with Breast Plate |
| US20120270770A1 (en) * | 2010-08-03 | 2012-10-25 | Jesse Michael Jaynes | Anti-angiogenic peptides and their uses |
| US9056923B2 (en) * | 2010-12-10 | 2015-06-16 | The Johns Hopkins University | Mimetic peptides derived from collagen type IV and their use for treating angiogenesis- and lymphagiogenesis-dependent diseases |
| WO2012114759A1 (ja) | 2011-02-24 | 2012-08-30 | コニカミノルタホールディングス株式会社 | 活性光線硬化型インクジェットインク及び画像形成方法 |
| WO2014066811A1 (en) | 2012-10-25 | 2014-05-01 | The Johns Hopkins University | Bioreducible poly (b-amino ester)s for sirna delivery |
| WO2014066898A1 (en) | 2012-10-26 | 2014-05-01 | The Johns Hopkins University | A layer-by-layer approach to co-deliver dna and sirna via aunps: a potential platform for modifying release kinetics |
| HUE047735T2 (hu) * | 2013-06-07 | 2020-05-28 | Univ Johns Hopkins | Egy biometrikus peptid és biológiailag lebomló szállító rendszer az angiogenesis- és lymphangiogenesis függõ betegségek kezelésében |
-
2014
- 2014-06-09 HU HUE14807179A patent/HUE047735T2/hu unknown
- 2014-06-09 EP EP14807179.8A patent/EP3003343B1/en active Active
- 2014-06-09 EP EP19195992.3A patent/EP3643318A1/en active Pending
- 2014-06-09 JP JP2016518060A patent/JP6470740B2/ja active Active
- 2014-06-09 DK DK14807179.8T patent/DK3003343T3/da active
- 2014-06-09 ES ES14807179T patent/ES2774217T3/es active Active
- 2014-06-09 CA CA2914764A patent/CA2914764C/en active Active
- 2014-06-09 CN CN201911163740.6A patent/CN110981941A/zh active Pending
- 2014-06-09 AU AU2014274703A patent/AU2014274703B2/en active Active
- 2014-06-09 CN CN201480043222.XA patent/CN105431162B/zh active Active
- 2014-06-09 WO PCT/US2014/041526 patent/WO2014197892A1/en active Application Filing
- 2014-06-09 US US14/896,521 patent/US9802984B2/en active Active
-
2015
- 2015-11-24 IL IL242760A patent/IL242760B/en active IP Right Grant
-
2016
- 2016-09-07 HK HK16110656.6A patent/HK1222542A1/zh unknown
-
2017
- 2017-09-22 US US15/712,890 patent/US10774112B2/en active Active
-
2019
- 2019-01-18 JP JP2019006590A patent/JP6931011B2/ja active Active
-
2020
- 2020-08-10 US US16/989,416 patent/US11981754B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20200361993A1 (en) | 2020-11-19 |
| US10774112B2 (en) | 2020-09-15 |
| CN105431162A (zh) | 2016-03-23 |
| JP6931011B2 (ja) | 2021-09-01 |
| CA2914764C (en) | 2021-10-26 |
| CN110981941A (zh) | 2020-04-10 |
| CA2914764A1 (en) | 2014-12-11 |
| EP3643318A1 (en) | 2020-04-29 |
| JP6470740B2 (ja) | 2019-02-13 |
| ES2774217T3 (es) | 2020-07-17 |
| AU2014274703B2 (en) | 2019-07-04 |
| EP3003343B1 (en) | 2019-10-23 |
| JP2016521712A (ja) | 2016-07-25 |
| US11981754B2 (en) | 2024-05-14 |
| EP3003343A1 (en) | 2016-04-13 |
| WO2014197892A1 (en) | 2014-12-11 |
| CN105431162B (zh) | 2019-12-10 |
| US9802984B2 (en) | 2017-10-31 |
| HUE047735T2 (hu) | 2020-05-28 |
| DK3003343T3 (da) | 2020-02-03 |
| AU2014274703A1 (en) | 2015-12-10 |
| JP2019089790A (ja) | 2019-06-13 |
| US20160122390A1 (en) | 2016-05-05 |
| IL242760B (en) | 2021-03-25 |
| US20180134753A1 (en) | 2018-05-17 |
| EP3003343A4 (en) | 2016-11-30 |
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