ES2763089T3 - Agente para la medición de endotoxinas - Google Patents
Agente para la medición de endotoxinas Download PDFInfo
- Publication number
- ES2763089T3 ES2763089T3 ES17190094T ES17190094T ES2763089T3 ES 2763089 T3 ES2763089 T3 ES 2763089T3 ES 17190094 T ES17190094 T ES 17190094T ES 17190094 T ES17190094 T ES 17190094T ES 2763089 T3 ES2763089 T3 ES 2763089T3
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- Prior art keywords
- factor
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- endotoxin
- dna
- present specification
- Prior art date
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Classifications
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
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- G—PHYSICS
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- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
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- G—PHYSICS
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- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
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- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96402—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals
- G01N2333/96405—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general
- G01N2333/96408—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general with EC number
- G01N2333/96411—Serine endopeptidases (3.4.21)
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N2400/50—Lipopolysaccharides; LPS
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
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| ES12710808.2T Active ES2650170T3 (es) | 2011-02-28 | 2012-02-28 | Agente para la medición de endotoxinas |
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| WO (1) | WO2012118226A1 (OSRAM) |
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| EP2740791A1 (en) * | 2012-12-05 | 2014-06-11 | MicroCoat Biotechnologie GmbH | Method for recombinant production of horseshoe crab Factor C protein in protozoa |
| CN108646019B (zh) | 2012-12-10 | 2021-06-25 | 生化学工业株式会社 | 新重组因子c、其制造方法、及内毒素的测定法 |
| ES2816550T3 (es) | 2012-12-28 | 2021-04-05 | Seikagaku Kogyo Co Ltd | Método de pre-tratamiento para antitrombina III que se va a someter a una prueba de Limulus |
| JP6562765B2 (ja) * | 2015-08-13 | 2019-08-21 | 大日本印刷株式会社 | 電気化学式エンドトキシン濃度検出用容器、電極チップおよびエンドトキシンの検出方法 |
| JP6557090B2 (ja) * | 2015-08-13 | 2019-08-07 | 大日本印刷株式会社 | 電極チップおよび電極チップの製造方法 |
| KR20180107127A (ko) * | 2016-01-28 | 2018-10-01 | 킴벌리-클라크 월드와이드, 인크. | Rna 바이러스에 대한 유착 조성물 및 표면으로부터 rna 바이러스를 제거하는 방법 |
| EP3418730A4 (en) | 2016-02-16 | 2019-10-30 | Seikagaku Corporation | ELECTROCHEMICAL MEASUREMENT USING A PHENYLENEDIAMINE DERIVATIVE |
| CN105866080B (zh) * | 2016-04-05 | 2019-11-12 | 中国科学院苏州生物医学工程技术研究所 | 重组鲎三因子试剂及其检测内毒素的方法 |
| WO2018074498A1 (ja) | 2016-10-18 | 2018-04-26 | 生化学工業株式会社 | リムルス属由来の組換え蛋白質及びこれをコードするｄｎａ |
| AU2018227210B2 (en) | 2017-03-01 | 2023-11-09 | Seikagaku Corporation | Horseshoe crab factor B variant |
| CN108913707B (zh) * | 2018-07-23 | 2021-06-15 | 广东医科大学 | 一种特异性检测内毒素的试剂及其制备方法 |
| CN112639118A (zh) * | 2018-10-03 | 2021-04-09 | 生化学工业株式会社 | 内毒素测定剂的灵敏度的增强方法 |
| EP4137817A4 (en) | 2020-04-16 | 2024-08-07 | Kikkoman Corporation | HYDROLASE-USED METHOD FOR TRACE SUBSTANCE MEASUREMENT |
| FR3125336B1 (fr) * | 2021-07-19 | 2023-07-14 | Biomerieux Sa | Procédé de quantification d'endotoxines d'un échantillon biologique |
| US20250044296A1 (en) | 2021-08-04 | 2025-02-06 | Seikagaku Corporation | Reagent for measuring b-glucan, method for producing same and use thereof |
| CN114317504B (zh) * | 2021-12-28 | 2023-07-25 | 健帆生物科技集团股份有限公司 | 一种鲎因子c截短蛋白及其制备方法和应用 |
| WO2024254215A1 (en) * | 2023-06-05 | 2024-12-12 | Charles River Laboratories, Inc. | Recombinant amebocyte clotting factors and uses thereof |
| CN118581071B (zh) * | 2024-06-05 | 2025-10-10 | 郑州伊美诺生物技术有限公司 | 一种重组鲎试剂及其制备方法、应用 |
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| DK255887D0 (da) * | 1987-05-20 | 1987-05-20 | Claus Koch | Immunoassay |
| JP3322700B2 (ja) * | 1992-09-14 | 2002-09-09 | 生化学工業株式会社 | 固相系反応用エンドトキシン特異的測定剤 |
| JP3242733B2 (ja) * | 1993-02-26 | 2001-12-25 | 生化学工業株式会社 | エンドトキシン特異的測定剤 |
| JP3429036B2 (ja) * | 1993-09-30 | 2003-07-22 | 生化学工業株式会社 | エンドトキシンの特異的測定剤 |
| US5716834A (en) * | 1994-08-19 | 1998-02-10 | National University Of Singapore | Cloned factor C cDNA of the Singapore horseshoe crab, Carcinoscorpius rotundicauda and purification of factor C proenzyme |
| US6645724B1 (en) * | 1997-09-19 | 2003-11-11 | National University Of Singapore | Assays for endotoxin |
| EP1015609B1 (en) * | 1997-09-19 | 2004-09-01 | National University Of Singapore | A novel generation of cloned horseshoe crab recombinant factor c for detection and removal of endotoxin |
| WO2003002976A2 (en) * | 2001-06-28 | 2003-01-09 | Biowhittaker, Inc. | Methods and reagents for detecting endotoxin |
| JPWO2008004674A1 (ja) * | 2006-07-07 | 2009-12-10 | 生化学工業株式会社 | プロクロッティングエンザイム、並びに、これを用いたエンドトキシン又は（１→３）−β−Ｄ−グルカンの検出方法 |
| JP2011244760A (ja) * | 2010-05-28 | 2011-12-08 | Sumitomo Chemical Co Ltd | 生体組織再生を促進させる薬剤を製造するための加工細胞 |
| CN105866080B (zh) * | 2016-04-05 | 2019-11-12 | 中国科学院苏州生物医学工程技术研究所 | 重组鲎三因子试剂及其检测内毒素的方法 |
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2012
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- 2012-02-28 SG SG10201601351WA patent/SG10201601351WA/en unknown
- 2012-02-28 EP EP12710808.2A patent/EP2681564B1/en not_active Not-in-force
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- 2012-02-28 ES ES12710808.2T patent/ES2650170T3/es active Active
- 2012-02-28 CN CN201610799888.9A patent/CN106432457A/zh active Pending
- 2012-02-28 WO PCT/JP2012/055728 patent/WO2012118226A1/en not_active Ceased
- 2012-02-28 US US14/001,138 patent/US20140024062A1/en not_active Abandoned
- 2012-02-28 EP EP19160846.2A patent/EP3517962A1/en active Pending
- 2012-02-28 JP JP2013538748A patent/JP2014510898A/ja active Pending
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2015
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2016
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2018
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| EP2681564B1 (en) | 2017-10-25 |
| US20140024062A1 (en) | 2014-01-23 |
| SG10201601351WA (en) | 2016-03-30 |
| JP2022119887A (ja) | 2022-08-17 |
| WO2012118226A1 (en) | 2012-09-07 |
| JP2014510898A (ja) | 2014-05-01 |
| CN106432457A (zh) | 2017-02-22 |
| EP3273244B1 (en) | 2019-09-25 |
| EP2681564A1 (en) | 2014-01-08 |
| JP7590530B2 (ja) | 2024-11-26 |
| US20220018841A1 (en) | 2022-01-20 |
| SG192578A1 (en) | 2013-09-30 |
| US20180259527A1 (en) | 2018-09-13 |
| JP7372392B2 (ja) | 2023-10-31 |
| JP2020100622A (ja) | 2020-07-02 |
| ES2650170T3 (es) | 2018-01-17 |
| EP3273244A1 (en) | 2018-01-24 |
| US20170138945A1 (en) | 2017-05-18 |
| EP3517962A1 (en) | 2019-07-31 |
| CN103562724A (zh) | 2014-02-05 |
| SG10202110031YA (en) | 2021-10-28 |
| US11162949B2 (en) | 2021-11-02 |
| US20150252405A1 (en) | 2015-09-10 |
| JP6640267B2 (ja) | 2020-02-05 |
| JP2024010024A (ja) | 2024-01-23 |
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