ES2757675T3 - Anticuerpos para el tratamiento de la infección y enfermedad asociada a Clostridium difficile - Google Patents
Anticuerpos para el tratamiento de la infección y enfermedad asociada a Clostridium difficile Download PDFInfo
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- ES2757675T3 ES2757675T3 ES11769680T ES11769680T ES2757675T3 ES 2757675 T3 ES2757675 T3 ES 2757675T3 ES 11769680 T ES11769680 T ES 11769680T ES 11769680 T ES11769680 T ES 11769680T ES 2757675 T3 ES2757675 T3 ES 2757675T3
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- mab
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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Landscapes
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| EP3167899B1 (en) | 2010-09-03 | 2021-03-24 | Valneva Austria GmbH | Isolated polypeptide of the toxin a and toxin b proteins of c.difficile and uses thereof |
| CA2845884A1 (en) | 2011-08-22 | 2013-02-28 | Cangene Corporation | Clostridium difficile antibodies |
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| SG11201402375VA (en) * | 2011-12-08 | 2014-10-30 | Novartis Ag | Clostridium difficile toxin-based vaccine |
| CN102590515B (zh) * | 2012-01-13 | 2014-07-30 | 张春华 | 艰难梭菌外毒素a检测试剂盒及组成该试剂盒的单克隆抗体 |
| AU2013212264B2 (en) * | 2012-01-23 | 2017-05-18 | Santalis Pharmaceuticals Inc. | Sandalwood oil and its uses related to clostridium infections |
| RU2628305C2 (ru) | 2012-03-02 | 2017-08-15 | Регенерон Фармасьютиказ, Инк. | Человеческие антитела к токсинам clostridium difficile |
| GB201206070D0 (en) | 2012-04-04 | 2012-05-16 | Health Prot Agency | Clostridium difficile antigens |
| EP2921502A4 (en) | 2012-10-19 | 2016-09-28 | Evec Inc | AGAINST TOXIN FROM CLOSTRIDIUM DIFFICILE OR ANTIGENBINDING FRAGMENT SPECIFIC HUMAN ANTIBODY |
| JP2016501877A (ja) * | 2012-11-28 | 2016-01-21 | シーエヌジェー ホールディングス，インコーポレイテッド | クロストリジウム・ディフィシルに対する抗体 |
| CN107880126B (zh) | 2012-12-21 | 2021-03-30 | 西雅图基因公司 | 抗ntb-a抗体及相关组合物和方法 |
| EP4079760A3 (en) | 2013-03-15 | 2023-01-25 | Sanofi Pasteur Inc. | Antibodies against clostridium difficile toxins and methods of using the same |
| CN105555309A (zh) * | 2013-04-19 | 2016-05-04 | 英穆伦有限公司 | 治疗和/或预防艰难梭菌相关疾病的方法和组合物 |
| CA2910200A1 (en) | 2013-04-22 | 2014-10-30 | Board Of Regents Of The University Of Oklahoma | Clostridium difficile vaccine and methods of use |
| US10513552B2 (en) | 2014-06-20 | 2019-12-24 | Immunimed Inc. | Use of polyclonal antibodies against clostridium difficile for treatment of inflammatory bowel disease |
| EP2957570B1 (en) | 2014-06-20 | 2019-04-17 | Immunimed Inc. | Polyclonal antibodies against clostridium difficile and uses thereof |
| WO2016156474A1 (en) | 2015-03-31 | 2016-10-06 | Vhsquared Limited | Polypeptide comprising an immunoglobulin chain variable domain which binds to clostridium difficile toxin a |
| WO2016156475A1 (en) | 2015-03-31 | 2016-10-06 | Vhsquared Limited | Polypeptide comprising an immunoglobulin chain variable domain which binds to clostridium difficile toxin b |
| JP2018517670A (ja) * | 2015-04-15 | 2018-07-05 | メディミューン，エルエルシー | クロストリジウム・ディフィシル（Ｃｌｏｓｔｒｉｄｉｕｍ ｄｉｆｆｉｃｉｌｅ）感染および関連疾患の治療方法 |
| GB201509326D0 (en) * | 2015-05-29 | 2015-07-15 | Antibio Tx Aps | Novel use |
| EP3344276B1 (en) | 2015-09-03 | 2020-04-22 | The Board of Regents of the University of Oklahoma | Peptide inhibitors of clostridium difficile tcdb toxin |
| SG11201808246SA (en) * | 2016-03-24 | 2018-10-30 | Paratek Pharm Innc | Methods for treating and preventing c. difficile infection |
| US11185555B2 (en) | 2016-04-11 | 2021-11-30 | Noah James Harrison | Method to kill pathogenic microbes in a patient |
| US11326182B2 (en) | 2016-04-29 | 2022-05-10 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| WO2017189964A2 (en) * | 2016-04-29 | 2017-11-02 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| WO2018148537A1 (en) * | 2017-02-10 | 2018-08-16 | Stc. Unm | Recombinant expression systems and products |
| JP7339262B2 (ja) * | 2018-01-12 | 2023-09-05 | アムジェン インコーポレイテッド | Ｐａｃ１抗体及びその使用 |
| GB201807367D0 (en) * | 2018-05-04 | 2018-06-20 | Univ Newcastle | Biomarker |
| RU2694549C1 (ru) * | 2018-08-16 | 2019-07-16 | Федеральное государственное автономное учреждение "Национальный медицинский исследовательский центр здоровья детей" Министерства здравоохранения Российской Федерации (ФГАУ "НМИЦ здоровья детей" Минздрава России) | Способ ведения детей с болезнью Гиршпрунга в периоперационном периоде |
| WO2021219786A1 (en) * | 2020-04-30 | 2021-11-04 | Gottfried Himmler | Anti-toxin secretory iga2 preparation |
| CN111499738B (zh) * | 2020-06-03 | 2022-04-05 | 郑州师范学院 | 一种抗艰难梭菌肠毒素a的抗体 |
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| US5292668A (en) | 1981-12-21 | 1994-03-08 | Boston Biomedical Research Institute, Inc. | Bispecific antibody determinants |
| US4879218A (en) * | 1982-09-13 | 1989-11-07 | Virginia Tech Intellectual Properties, Inc. | Antibody for C.difficile |
| US6071517A (en) | 1986-07-07 | 2000-06-06 | Medarex, Inc. | Bispecific heteroantibodies with dual effector functions |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5175384A (en) | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US5231003A (en) | 1990-05-11 | 1993-07-27 | Cambridge Bioscience Corporation | Monoclonal antibodies specific for toxin b of clostridium difficile |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5932448A (en) | 1991-11-29 | 1999-08-03 | Protein Design Labs., Inc. | Bispecific antibody heterodimers |
| EP0690452A3 (en) | 1994-06-28 | 1999-01-07 | Advanced Micro Devices, Inc. | Electrically erasable memory and method of erasure |
| US20100081792A1 (en) | 2001-06-28 | 2010-04-01 | Smithkline Beecham Corporation | Ligand |
| US7235641B2 (en) | 2003-12-22 | 2007-06-26 | Micromet Ag | Bispecific antibodies |
| DK1766093T3 (da) * | 2004-02-06 | 2011-10-03 | Univ Massachusetts | Antistoffer mod clostridium difficile-toksiner og anvendelse deraf |
| WO2006036834A2 (en) | 2004-09-24 | 2006-04-06 | Amgen Inc. | MODIFIED Fc MOLECULES |
| EP1833510A4 (en) * | 2004-12-27 | 2010-02-10 | Progenics Pharmaceuticals Neva | ORAL ADMINISTRATION ANTITOXIN ANTIBODIES AND METHODS OF MAKING AND USING THE SAME |
| US9963510B2 (en) | 2005-04-15 | 2018-05-08 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
| US7612181B2 (en) | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
| EP1820513A1 (en) | 2006-02-15 | 2007-08-22 | Trion Pharma Gmbh | Destruction of tumor cells expressing low to medium levels of tumor associated target antigens by trifunctional bispecific antibodies |
| EP2033657A1 (de) | 2007-09-04 | 2009-03-11 | Trion Pharma Gmbh | Intraoperative trifunktionale Antikörper-Applikation zur Prophylaxe intraperitonealer Tumorzelldissemination |
| JP5965389B2 (ja) | 2010-04-15 | 2016-08-03 | プロゲニクス ファーマシューティカルズ インコーポレーテッドＰｒｏｇｅｎｉｃｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | クロストリジウム・ディフィシル関連感染症および疾患を治療するための抗体 |
-
2011
- 2011-04-15 JP JP2013505183A patent/JP5965389B2/ja active Active
- 2011-04-15 US US13/641,315 patent/US8986697B2/en active Active
- 2011-04-15 EP EP11769680.7A patent/EP2558493B1/en active Active
- 2011-04-15 KR KR1020127029208A patent/KR101820987B1/ko active Active
- 2011-04-15 AU AU2011239470A patent/AU2011239470B2/en active Active
- 2011-04-15 BR BR112012026021-9A patent/BR112012026021B1/pt active IP Right Grant
- 2011-04-15 CN CN201180024312.0A patent/CN102947334B/zh active Active
- 2011-04-15 WO PCT/US2011/032713 patent/WO2011130650A2/en not_active Ceased
- 2011-04-15 MX MX2012011926A patent/MX339253B/es active IP Right Grant
- 2011-04-15 ES ES11769680T patent/ES2757675T3/es active Active
- 2011-04-15 CA CA2795953A patent/CA2795953C/en active Active
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2015
- 2015-03-09 US US14/642,342 patent/US20150175681A1/en not_active Abandoned
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2016
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Also Published As
| Publication number | Publication date |
|---|---|
| CN102947334A (zh) | 2013-02-27 |
| EP2558493A4 (en) | 2013-11-27 |
| KR101820987B1 (ko) | 2018-01-22 |
| MX2012011926A (es) | 2013-01-29 |
| KR20130062279A (ko) | 2013-06-12 |
| EP2558493A2 (en) | 2013-02-20 |
| CA2795953A1 (en) | 2011-10-20 |
| US20130202618A1 (en) | 2013-08-08 |
| MX339253B (es) | 2016-05-18 |
| US20150175681A1 (en) | 2015-06-25 |
| AU2011239470A1 (en) | 2012-11-01 |
| JP2013523190A (ja) | 2013-06-17 |
| WO2011130650A2 (en) | 2011-10-20 |
| EP2558493B1 (en) | 2019-09-18 |
| CA2795953C (en) | 2021-09-14 |
| BR112012026021B1 (pt) | 2022-05-03 |
| JP2017012166A (ja) | 2017-01-19 |
| AU2011239470B2 (en) | 2015-09-10 |
| CN102947334B (zh) | 2017-12-26 |
| US8986697B2 (en) | 2015-03-24 |
| WO2011130650A3 (en) | 2012-04-12 |
| BR112012026021A2 (pt) | 2020-04-14 |
| JP6159854B2 (ja) | 2017-07-05 |
| JP5965389B2 (ja) | 2016-08-03 |
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