ES2744339T3 - Compuestos - Google Patents
Compuestos Download PDFInfo
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- ES2744339T3 ES2744339T3 ES15824385T ES15824385T ES2744339T3 ES 2744339 T3 ES2744339 T3 ES 2744339T3 ES 15824385 T ES15824385 T ES 15824385T ES 15824385 T ES15824385 T ES 15824385T ES 2744339 T3 ES2744339 T3 ES 2744339T3
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| US11273176B2 (en) | 2016-03-02 | 2022-03-15 | The Brigham And Women's Hospital, Inc. | Use of PLA2G5-deficient suppressive macrophages in suppression of inflammation |
| ES2907130T3 (es) * | 2017-09-26 | 2022-04-22 | Inst Nat Sante Rech Med | Darapladib radiomarcado, análogos del mismo y su uso como compuestos para la obtención de imágenes |
| CN109988126B (zh) * | 2017-12-29 | 2023-05-16 | 南京富润凯德生物医药有限公司 | 一种3-氨基-氧杂环丁烷衍生物及其制备方法和应用 |
| CN109134523A (zh) * | 2018-09-30 | 2019-01-04 | 中昊(大连)化工研究设计院有限公司 | 一种3，6-二氢-2h-吡喃-4-硼酸频哪醇酯的合成新工艺 |
| JP2022116370A (ja) * | 2019-06-13 | 2022-08-10 | アグロカネショウ株式会社 | 新規な１－ベンジルアミン誘導体及びこれを有効成分とする農園芸用薬剤 |
| CN112574221B (zh) * | 2019-09-30 | 2022-03-04 | 上海纽思克生物科技有限公司 | 四环嘧啶酮类化合物、其制备方法、其组合物和用途 |
| CN114805389B (zh) * | 2019-11-09 | 2023-08-29 | 上海赛默罗生物科技有限公司 | 三环二氢咪唑并嘧啶酮衍生物、其制备方法、药物组合物和用途 |
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| JP7595964B2 (ja) * | 2020-05-13 | 2024-12-09 | 上海紐思克生物科技有限公司 | 架橋環状ピリミジノン類化合物、その製造方法、その組成物及び使用 |
| CN113861220B (zh) * | 2020-06-30 | 2023-06-16 | 上海纽思克生物科技有限公司 | 三环嘧啶酮类化合物、其制备方法、其组合物和用途 |
| CN113912622B (zh) * | 2020-07-10 | 2023-12-01 | 上海纽思克生物科技有限公司 | 三环嘧啶酮类化合物、其制备方法、其组合物和用途 |
| CN115304620A (zh) | 2021-05-07 | 2022-11-08 | 上海赛默罗生物科技有限公司 | 嘧啶酮衍生物、其制备方法、药物组合物和用途 |
| CN114057740B (zh) * | 2021-12-15 | 2024-04-02 | 上海赛默罗生物科技有限公司 | 螺环嘧啶酮衍生物、其制备方法、药物组合物和用途 |
| JP2025527291A (ja) * | 2022-08-04 | 2025-08-20 | ４ビー テクノロジーズ （ベイジン） カンパニー リミテッド | Ｌｐ－ＰＬＡ２阻害剤としてのジヒドロイミダゾピリミジノン化合物およびその使用 |
| JP2026516205A (ja) * | 2023-04-18 | 2026-05-20 | サイニューロ セラピューティクス インコーポレイテッド | Ｌｐ－ｐｌａ２阻害剤と第２の薬剤の併用治療 |
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| WO2025217646A1 (en) * | 2024-04-12 | 2025-10-16 | Scineuro Therapeutics Inc. | Method of treating neurodegenerative and ocular neovascular diseases |
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| WO2009147476A1 (en) | 2008-06-02 | 2009-12-10 | Matrix Laboratories Ltd. | Novel pde inhibitors, pharmaceutical compositions containing them and processes for their preparation |
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| EP3172211B1 (en) * | 2014-07-22 | 2019-07-03 | GlaxoSmithKline Intellectual Property Development Limited | Tricyclic imidazo-pyrimidinone derivatives for the treatment of diseases mediated by lp-pla2 |
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