ES2742035T3 - Tratamiento de las enfermedades de la disfunción y la inflamación endotelial - Google Patents
Tratamiento de las enfermedades de la disfunción y la inflamación endotelial Download PDFInfo
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- ES2742035T3 ES2742035T3 ES13862555T ES13862555T ES2742035T3 ES 2742035 T3 ES2742035 T3 ES 2742035T3 ES 13862555 T ES13862555 T ES 13862555T ES 13862555 T ES13862555 T ES 13862555T ES 2742035 T3 ES2742035 T3 ES 2742035T3
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Classifications
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
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- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
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Applications Claiming Priority (2)
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| US201261736361P | 2012-12-12 | 2012-12-12 | |
| PCT/AU2013/001452 WO2014089623A1 (en) | 2012-12-12 | 2013-12-12 | Treatment of diseases of endothelial dysfunction and inflammation |
Publications (1)
| Publication Number | Publication Date |
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| ES2742035T3 true ES2742035T3 (es) | 2020-02-12 |
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| ES13862555T Active ES2742035T3 (es) | 2012-12-12 | 2013-12-12 | Tratamiento de las enfermedades de la disfunción y la inflamación endotelial |
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| ES2742035T3 (es) * | 2012-12-12 | 2020-02-12 | Mesoblast Inc | Tratamiento de las enfermedades de la disfunción y la inflamación endotelial |
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| US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
| AU8200191A (en) | 1990-07-09 | 1992-02-04 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | High efficiency packaging of mutant adeno-associated virus using amber suppressions |
| US5173414A (en) | 1990-10-30 | 1992-12-22 | Applied Immune Sciences, Inc. | Production of recombinant adeno-associated virus vectors |
| ATE237694T1 (de) | 1991-08-20 | 2003-05-15 | Us Gov Health & Human Serv | Adenovirus vermittelter gentransfer in den gastrointestinaltrakt |
| PT1493439E (pt) * | 1997-04-02 | 2012-01-10 | Brigham & Womens Hospital | Meio de avaliação do perfil de risco de um indivíduo para uma doença aterosclerótica |
| AUPQ147799A0 (en) | 1999-07-07 | 1999-07-29 | Medvet Science Pty. Ltd. | Mesenchymal precursor cell |
| AU2003901668A0 (en) | 2003-03-28 | 2003-05-01 | Medvet Science Pty. Ltd. | Non-haemopoietic precursor cells |
| DE19939781C2 (de) | 1999-08-21 | 2003-06-18 | Schott Glas | Skulltiegel für das Erschmelzen oder das Läutern von anorganischen Substanzen, insbesondere von Gläsern und Glaskeramiken |
| US20080095749A1 (en) * | 2004-03-22 | 2008-04-24 | Sudeepta Aggarwal | Mesenchymal stem cells and uses therefor |
| CN102391981B (zh) | 2004-09-24 | 2014-08-20 | 麦索布莱斯特公司 | 多能扩增间充质前体细胞子代(memp)及其应用 |
| WO2006108229A1 (en) | 2005-04-12 | 2006-10-19 | Angioblast Systems, Inc. | Isolation of adult multipotential cells by tissue non-specific alkaline phosphatase |
| WO2006121445A2 (en) * | 2005-05-10 | 2006-11-16 | United States Of America Department Of Veteran's Affairs | Therapy of kidney diseases and multiorgan failure with mesenchymal stem cells and mesenchymal stem cell conditioned media |
| US20080260703A1 (en) * | 2007-04-23 | 2008-10-23 | Medistem Labortories | Treatment of Insulin Resistance and Diabetes |
| CA2743682A1 (en) * | 2007-11-30 | 2009-06-11 | New York Medical College | Methods of reducing transplant rejection and cardiac allograft vasculopathy by implanting autologous stem cells |
| CA2743698A1 (en) * | 2007-11-30 | 2009-06-11 | New York Medical College | Compositions comprising vascular and myocyte progenitor cells and methods of their use |
| CN101939417B (zh) * | 2007-12-04 | 2014-02-05 | 蛋白生物动力私人有限公司 | 祖细胞的保护和它们的分化的调节 |
| CN102076844B (zh) * | 2008-06-30 | 2013-08-07 | 成血管细胞系统公司 | 采用组合疗法的眼病和过度血管新生的治疗 |
| CN104546912B (zh) * | 2008-11-20 | 2019-11-08 | 中胚有限公司 | 用于治疗胰功能异常的方法 |
| WO2010138180A2 (en) * | 2009-05-26 | 2010-12-02 | The University Of Vermont And State Agriculture College | Compositions and methods for cardiac tissue repair |
| WO2011073521A1 (en) * | 2009-12-15 | 2011-06-23 | Petri Salven | Methods for enriching adult-derived endothelial progenitor cells and uses thereof |
| US20120195969A1 (en) * | 2010-09-29 | 2012-08-02 | Aidan Research And Consulting, Llc | Treatment of acne by conditioned media |
| US9405700B2 (en) | 2010-11-04 | 2016-08-02 | Sonics, Inc. | Methods and apparatus for virtualization in an integrated circuit |
| CA2837895C (en) * | 2011-06-03 | 2021-07-27 | Mesoblast, Inc. | Methods of treating or preventing neurological diseases |
| ES3013463T3 (en) * | 2011-07-04 | 2025-04-14 | Mesoblast Inc | Treating or preventing rheumatic disease |
| CA2880808C (en) * | 2012-08-01 | 2023-01-24 | United Therapeutics Corporation | Treatment of pulmonary arterial hypertension with mesenchymal stem cells |
| ES2742035T3 (es) * | 2012-12-12 | 2020-02-12 | Mesoblast Inc | Tratamiento de las enfermedades de la disfunción y la inflamación endotelial |
| ES2963968T3 (es) * | 2013-01-09 | 2024-04-03 | United Therapeutics Corp | Tratamiento de la vasculopatía con prostaciclina y células madre mesenquimatosas |
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2015
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2019
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