ES2738315T3 - Composiciones terapéuticas y procedimientos que implican la transfección de ARNm - Google Patents
Composiciones terapéuticas y procedimientos que implican la transfección de ARNm Download PDFInfo
- Publication number
- ES2738315T3 ES2738315T3 ES14738078T ES14738078T ES2738315T3 ES 2738315 T3 ES2738315 T3 ES 2738315T3 ES 14738078 T ES14738078 T ES 14738078T ES 14738078 T ES14738078 T ES 14738078T ES 2738315 T3 ES2738315 T3 ES 2738315T3
- Authority
- ES
- Spain
- Prior art keywords
- mrna
- cells
- cell
- protein
- expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361751504P | 2013-01-11 | 2013-01-11 | |
| PCT/US2014/011041 WO2014110366A1 (en) | 2013-01-11 | 2014-01-10 | Therapeutic compositions and methods involving mrna transfection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2738315T3 true ES2738315T3 (es) | 2020-01-21 |
Family
ID=51167392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14738078T Active ES2738315T3 (es) | 2013-01-11 | 2014-01-10 | Composiciones terapéuticas y procedimientos que implican la transfección de ARNm |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20150344537A1 (https=) |
| EP (2) | EP2943226B1 (https=) |
| JP (4) | JP2016511230A (https=) |
| KR (2) | KR102119985B1 (https=) |
| CN (1) | CN105473163A (https=) |
| AU (1) | AU2014205298B2 (https=) |
| CA (2) | CA2901409C (https=) |
| ES (1) | ES2738315T3 (https=) |
| IL (2) | IL239898B (https=) |
| NZ (1) | NZ710495A (https=) |
| PL (1) | PL2943226T3 (https=) |
| SG (2) | SG11201505431XA (https=) |
| WO (1) | WO2014110366A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150344537A1 (en) * | 2013-01-11 | 2015-12-03 | Mark C. Herzberg | Non-Transgene Transfection for Therapeutic Purposes |
| US11253570B2 (en) | 2016-11-07 | 2022-02-22 | Medizinische Hochschule Hannover (Mhh) | S100A8/S100A9-induced immunotolerance in newborn subjects |
| CN107841508A (zh) * | 2017-11-29 | 2018-03-27 | 重庆市中医院 | 含抑铁素重组减毒沙门杆菌及构建方法、表达或递送载体 |
| EP3553523A1 (en) * | 2018-04-12 | 2019-10-16 | Koninklijke Philips N.V. | Diagnostics of mild or advanced periodontitis |
| EP3553525A1 (en) * | 2018-04-12 | 2019-10-16 | Koninklijke Philips N.V. | Diagnostics of mild or advanced periodontitis |
| JP6891157B2 (ja) * | 2018-11-15 | 2021-06-18 | 正生 池本 | 機能性ペプチド、それを用いた大腸炎用医薬およびデリバリー剤 |
| CN114561381A (zh) * | 2022-03-14 | 2022-05-31 | 桂林医学院 | 免疫mRNA及其制备方法和应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2797402B1 (fr) * | 1999-07-15 | 2004-03-12 | Biomerieux Stelhys | Utilisation d'un polypeptide pour detecter, prevenir ou traiter un etat pathologique associe a une maladie degenerative, neurologique ou autoimmune |
| WO2001023002A1 (en) * | 1999-09-30 | 2001-04-05 | National Jewish Medical And Research Center | Method for inhibition of pathogenic microorganisms |
| WO2002022686A2 (en) * | 2000-09-15 | 2002-03-21 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, National Institutes Of Health, Office Of Technology Transfer | Defensin-antigen fusion proteins |
| US7338936B2 (en) * | 2000-11-28 | 2008-03-04 | House Ear Institute | Use of antimicrobial proteins and peptides for the treatment of otitis media and paranasal sinusitis |
| DE10121254A1 (de) * | 2001-04-30 | 2002-11-07 | Switch Biotech Ag | MRP8/MRP14 Heterodimers oder seiner Einzelkomponenten alleine oder in Kombination zur Behandlung und/oder Prävention von Hauterkrankungen, Wunden und/oder Wundheilungsstörungen, die durch eine verringerte Menge an MRP8/MRP14 Heterodimeren gekennzeichnet sind |
| US20070123455A1 (en) * | 2003-04-04 | 2007-05-31 | Joel Palefsky | Immunomodulatory agents for treatment of inflammatory diseases |
| DE10324997A1 (de) * | 2003-06-03 | 2004-12-23 | Switch Biotech Ag | Mrp8/Mrp14 Inhibitoren und ihre Verwendung zur Prävention und/oder Behandlung von hypertrophen Narben und Keloiden |
| WO2005084180A2 (en) | 2003-12-19 | 2005-09-15 | University Of Cincinnati | Polyamides and polyamide complexes for delivery of oligonucleotide decoys |
| WO2006085987A2 (en) * | 2004-07-09 | 2006-08-17 | University Of Iowa Research Foundation | Rna interference in respiratory epitheial cells |
| WO2006078717A2 (en) * | 2005-01-19 | 2006-07-27 | Beth Israel Deaconess Medical Center | Lipocalin 2 for the treatment, prevention, and management of cancer metastasis, angiogenesis, and fibrosis |
| KR100681763B1 (ko) * | 2005-02-28 | 2007-02-15 | 재단법인 목암생명공학연구소 | 인간 리포칼린 2를 유효성분으로 포함하는 암 전이 억제용약학적 조성물, 이를 이용한 암 전이 억제 방법 |
| US8501478B2 (en) | 2006-06-15 | 2013-08-06 | University Of Cincinnati | Trehalose click polymers for delivery of biologically active molecules |
| US8679811B2 (en) * | 2007-06-11 | 2014-03-25 | The University Of Vermont And State Agricultural College | Treatments involving glutaredoxins and similar agents |
| US8916163B1 (en) * | 2007-12-21 | 2014-12-23 | Vanderbilt University | Method for treating microbial infections |
| DE102010040153A1 (de) * | 2010-09-02 | 2012-03-08 | Robert Bosch Gesellschaft Für Medizinische Forschung Mbh | Stoffkombination zur Behandlung von entzündlichen oder infektiösen Erkrankungen |
| EP2691101A2 (en) * | 2011-03-31 | 2014-02-05 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
| US10174081B2 (en) * | 2011-04-21 | 2019-01-08 | George Mason Research Foundation, Inc. | Antimicrobial peptides and uses therefore |
| US20150344537A1 (en) * | 2013-01-11 | 2015-12-03 | Mark C. Herzberg | Non-Transgene Transfection for Therapeutic Purposes |
-
2014
- 2014-01-10 US US14/760,077 patent/US20150344537A1/en not_active Abandoned
- 2014-01-10 KR KR1020187006399A patent/KR102119985B1/ko active Active
- 2014-01-10 CA CA2901409A patent/CA2901409C/en active Active
- 2014-01-10 SG SG11201505431XA patent/SG11201505431XA/en unknown
- 2014-01-10 WO PCT/US2014/011041 patent/WO2014110366A1/en not_active Ceased
- 2014-01-10 CN CN201480011234.4A patent/CN105473163A/zh active Pending
- 2014-01-10 JP JP2015552801A patent/JP2016511230A/ja active Pending
- 2014-01-10 KR KR1020157021685A patent/KR102056511B1/ko active Active
- 2014-01-10 SG SG10201603946PA patent/SG10201603946PA/en unknown
- 2014-01-10 NZ NZ71049514A patent/NZ710495A/en unknown
- 2014-01-10 PL PL14738078T patent/PL2943226T3/pl unknown
- 2014-01-10 EP EP14738078.6A patent/EP2943226B1/en active Active
- 2014-01-10 AU AU2014205298A patent/AU2014205298B2/en active Active
- 2014-01-10 CA CA3152721A patent/CA3152721C/en active Active
- 2014-01-10 EP EP19155020.1A patent/EP3501551B1/en active Active
- 2014-01-10 ES ES14738078T patent/ES2738315T3/es active Active
-
2015
- 2015-07-12 IL IL239898A patent/IL239898B/en active IP Right Grant
-
2016
- 2016-11-08 JP JP2016218023A patent/JP6473729B2/ja active Active
-
2018
- 2018-10-05 JP JP2018190468A patent/JP6956059B2/ja active Active
- 2018-10-10 IL IL262252A patent/IL262252B/en not_active IP Right Cessation
-
2020
- 2020-04-07 US US16/842,489 patent/US11912744B2/en active Active
- 2020-11-09 JP JP2020186487A patent/JP2021019644A/ja not_active Withdrawn
-
2024
- 2024-01-30 US US18/427,711 patent/US12448421B2/en active Active
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