ES272880A1 - Procedure for the manufacture of fenilpirazolincarboxic acid stages (Machine-translation by Google Translate, not legally binding) - Google Patents

Abstract

Process for the preparation of phenyl pyrazolinecarboxylic acid esters, characterized in that an alkanol containing tertiary or quaternary basic nitrogen is esterified with a reactable functional derivative of a 1- (4'-carboxyphenyl) -3-phenylpyrazoline, which may contain lower alkyl groups in position 4 and phenyl or lower alkyl groups in position 5, to form compounds of the general formulas I and II ** (See formula) ** in which R1 means an unsubstituted phenyl radical, or substituted by halogen, lower alkyl groups or lower alkoxy groups, R2 means hydrogen or a lower alkyl radical, R3 means hydrogen, a lower alkyl group or an unsubstituted phenyl radical, or is further substituted by non-ionogenic substituents, with the exception of the nitro group, X means a lower alkylene radical, R4 and R5 signify, independently of one another, a group each of lower alkyl, hydroxyalkyl, alkoxyalkyl, hydroxyalkyleneoxyalkyl, cyanalkyl or aralkyl, while R4 and R5 together with the nitrogen atom, optionally including oxygen or more nitrogen, also mean a heterocycle, R6 means an aralkyl or alkyl radical, optionally substituted inertly, and And it means the anion of an acid, and, if the obtained ester corresponds to the general formula I, this is quaternized, if desired, with a reactable compound of the general formula III R6 - Y (III) wherein R6 and Y have the meaning expressed above, to form a compound of the general formula II. (Machine-translation by Google Translate, not legally binding)