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AH Robins Co Inc
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AH Robins Co Inc
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Priority claimed from US431440Aexternal-prioritypatent/US3347856A/en
Application filed by AH Robins Co IncfiledCriticalAH Robins Co Inc
Publication of ES322716A1publicationCriticalpatent/ES322716A1/en
A method for the production of an anticholinergic compound selected from (a) those having the formula: ** (See formula) ** wherein R is a lower alkyl radical having from 1 to 4 carbon atoms inclusive in which R 'is selected from the group consisting of methyl and hydrogen, with a maximum of two R' other than hydrogen, in which A is a radical selected from the group consisting of hydrogen, lower alkyl having from 1 to 6 carbon atoms, inclusive, and lower cycloalkyl having from 3 to 9 carbon atoms, inclusive and in which A 'is a group of monocarbocyclic aryl containing a maximum of 15 carbon atoms selected from the group consisting of phenyl, trifluoromethylphenyl, phenyl lower alkoxy, di-lower alkyl, aminophenyl, lower alkyl and halophenyl, lower alkyl having from 1 to 6 carbon atoms inclusive and lower cycloalkyl having from 3 to 9 carbon atoms, inclusive, and wherein A and A "together with the nitrogen atom is the radical of a heterocyclic group comprising at least one closed ring and having and 4 to 12 carbon atoms inclusive, and (b) pharmaceutically acceptable acid addition salts thereof, characterized in that a compound selected from those having the formula is mixed and reacted together: ** (See formula) ** and metal salts thereof, with a compound having the formula ** (See formula) ** wherein X is halogen and R, R ', A and A' have the values previously assigned. (Machine-translation by Google Translate, not legally binding)
ES0322716A1965-02-091966-02-07Method for the production of an anticolinergic compound. (Machine-translation by Google Translate, not legally binding)
ExpiredES322716A1
(en)
Procedure for the obtaining of 3 ', 4', 5 ', - trimetoxi-3- amino-acrilo-fenonas. (Machine-translation by Google Translate, not legally binding)
A procedure for the preparation of acil-anylides with basic substitutors and their derivatives (Machine-translation by Google Translate, not legally binding)