ES2718828T3 - Conjunto de aguja de pluma para administrar soluciones de medicamentos - Google Patents
Conjunto de aguja de pluma para administrar soluciones de medicamentos Download PDFInfo
- Publication number
- ES2718828T3 ES2718828T3 ES10749302T ES10749302T ES2718828T3 ES 2718828 T3 ES2718828 T3 ES 2718828T3 ES 10749302 T ES10749302 T ES 10749302T ES 10749302 T ES10749302 T ES 10749302T ES 2718828 T3 ES2718828 T3 ES 2718828T3
- Authority
- ES
- Spain
- Prior art keywords
- needle
- skin
- diameter
- contact surface
- pen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000003814 drug Substances 0.000 title description 18
- 229940079593 drug Drugs 0.000 title description 11
- 230000014759 maintenance of location Effects 0.000 claims description 8
- 230000000717 retained effect Effects 0.000 claims description 2
- 210000003491 skin Anatomy 0.000 description 37
- 238000002347 injection Methods 0.000 description 26
- 239000007924 injection Substances 0.000 description 26
- 238000010254 subcutaneous injection Methods 0.000 description 17
- 239000007929 subcutaneous injection Substances 0.000 description 17
- 229940090048 pen injector Drugs 0.000 description 15
- 238000003780 insertion Methods 0.000 description 7
- 230000037431 insertion Effects 0.000 description 7
- 238000005054 agglomeration Methods 0.000 description 6
- 230000002776 aggregation Effects 0.000 description 6
- 210000004207 dermis Anatomy 0.000 description 6
- 210000002615 epidermis Anatomy 0.000 description 6
- 238000007920 subcutaneous administration Methods 0.000 description 6
- 239000000725 suspension Substances 0.000 description 6
- 230000000712 assembly Effects 0.000 description 4
- 238000000429 assembly Methods 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 230000004927 fusion Effects 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 238000013019 agitation Methods 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- 230000036512 infertility Effects 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 238000005192 partition Methods 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000036558 skin tension Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 241000282898 Sus scrofa Species 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/34—Trocars; Puncturing needles
- A61B17/3494—Trocars; Puncturing needles with safety means for protection against accidental cutting or pricking, e.g. limiting insertion depth, pressure sensors
- A61B17/3496—Protecting sleeves or inner probes; Retractable tips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3293—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle hub
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
- A61M5/347—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub rotatable, e.g. bayonet or screw
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
- A61M5/425—Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49815—Disassembling
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20905009P | 2009-03-03 | 2009-03-03 | |
| PCT/US2010/026129 WO2010102067A2 (en) | 2009-03-03 | 2010-03-03 | Pen needle assembly for delivering drug solutions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2718828T3 true ES2718828T3 (es) | 2019-07-04 |
Family
ID=42710213
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES19150458T Active ES2877190T3 (es) | 2009-03-03 | 2010-03-03 | Combinación de cubo de aguja y carcasa para su uso con un inyector de pluma |
| ES10749302T Active ES2718828T3 (es) | 2009-03-03 | 2010-03-03 | Conjunto de aguja de pluma para administrar soluciones de medicamentos |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES19150458T Active ES2877190T3 (es) | 2009-03-03 | 2010-03-03 | Combinación de cubo de aguja y carcasa para su uso con un inyector de pluma |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US9445838B2 (enExample) |
| EP (3) | EP2403572B1 (enExample) |
| JP (2) | JP6084772B2 (enExample) |
| CN (1) | CN102413858B (enExample) |
| ES (2) | ES2877190T3 (enExample) |
| WO (1) | WO2010102067A2 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8622961B2 (en) * | 2009-12-22 | 2014-01-07 | Becton, Dickinson & Company | Safety needle assembly with displaceable locking tongue |
| CN102858395B (zh) * | 2010-03-26 | 2015-04-22 | 赛诺菲-安万特德国有限公司 | 专用针头组件 |
| US20130035660A1 (en) | 2011-08-01 | 2013-02-07 | Alcyone Lifesciences, Inc. | Multidirectional microfluidic drug delivery devices with conformable balloons |
| US9224945B2 (en) * | 2012-08-30 | 2015-12-29 | Micron Technology, Inc. | Resistive memory devices |
| EP2934627B1 (en) | 2012-12-18 | 2021-04-07 | Alcyone Lifesciences, Inc. | Devices and methods for reducing or preventing backflow in a delivery system |
| ES2712691T3 (es) | 2012-12-26 | 2019-05-14 | Becton Dickinson Co | Envase de aguja de pluma |
| JP6599771B2 (ja) | 2012-12-26 | 2019-10-30 | ベクトン・ディキンソン・アンド・カンパニー | ペン針アセンブリ |
| EP2783721A1 (en) * | 2013-03-26 | 2014-10-01 | Sanofi-Aventis Deutschland GmbH | Needle assembly retainer |
| CN110215595B (zh) | 2013-06-17 | 2022-04-12 | 亚克安娜治疗学有限公司 | 导管末梢保护系统和立体定向固定装置 |
| ES2738298T3 (es) | 2013-07-31 | 2020-01-21 | Alcyone Lifesciences Inc | Sistemas y métodos de suministro de fármacos, tratamiento y monitoreo |
| KR102339184B1 (ko) * | 2013-10-18 | 2021-12-14 | 사노피-아벤티스 도이칠란트 게엠베하 | 주사 장치 |
| USD768850S1 (en) * | 2013-10-29 | 2016-10-11 | Htl-Strefa Spolka Akcyjna | Needle shield |
| USD770043S1 (en) * | 2013-10-29 | 2016-10-25 | Htl-Strefa Spolka Akcyjna | Needle hub |
| WO2016123494A1 (en) * | 2015-01-30 | 2016-08-04 | Becton, Dickinson And Company | Pen needle hub with a patient contact surface |
| US10709846B2 (en) * | 2013-12-04 | 2020-07-14 | Becton, Dickinson And Company | Pen needle attachment mechanisms |
| US11577030B2 (en) | 2013-12-04 | 2023-02-14 | Embecta Corp. | Pen needle attachment mechanisms |
| USD751192S1 (en) * | 2014-05-14 | 2016-03-08 | Health Line International Corp. | Medical device |
| US10806396B2 (en) | 2015-01-26 | 2020-10-20 | Alcyone Lifesciences, Inc. | Drug delivery methods with tracer |
| CN107530507A (zh) * | 2015-04-29 | 2018-01-02 | 诺和诺德股份有限公司 | 用于注射装置的针组件 |
| USD878575S1 (en) * | 2015-11-24 | 2020-03-17 | Visionisti Oy | Hand operated medical instrument |
| WO2017120167A1 (en) | 2016-01-04 | 2017-07-13 | Alcyone Lifesciences, Inc. | Methods and devices for treating stroke |
| WO2017177086A1 (en) | 2016-04-08 | 2017-10-12 | Becton, Dickinson And Company | Syringe with a patient contact surface |
| USD804023S1 (en) * | 2016-04-14 | 2017-11-28 | Becton, Dickinson And Company | Pen needle inner shield |
| US11511053B2 (en) * | 2017-02-16 | 2022-11-29 | Embecta Corp. | Pen needle hub injection depth optimization |
| AU201816011S (en) * | 2018-04-27 | 2018-11-06 | Borla Ind | Connector for medical lines |
| USD892319S1 (en) | 2018-08-31 | 2020-08-04 | Carefusion 303, Inc. | Intravenous priming cap |
| JP7619555B2 (ja) * | 2020-10-02 | 2025-01-22 | 富士フイルム株式会社 | 投与キット |
| JP1736238S (ja) * | 2022-09-13 | 2023-02-07 | 医療用注射針 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2567001A (en) * | 1950-02-06 | 1951-09-04 | Thomas E Watson | Hypodermic syringe |
| US3245567A (en) * | 1962-08-27 | 1966-04-12 | Johnson & Johnson | Sterile container |
| US3491575A (en) * | 1965-10-22 | 1970-01-27 | Continental Can Co | Wall ironing machine |
| US3491757A (en) * | 1966-12-30 | 1970-01-27 | Raul Olvera Arce | Hypodermic syringe with non-turning tip connector |
| US3739779A (en) * | 1970-04-28 | 1973-06-19 | Medical Electroscience & Pharm | Hypodermic syringe and needle construction |
| CA938850A (en) | 1970-07-24 | 1973-12-25 | W. Edwards Donald | Device for venipuncture |
| US4009716A (en) | 1976-02-17 | 1977-03-01 | Cohen Milton J | Needle-hub assembly for syringes |
| US4430080A (en) * | 1982-06-09 | 1984-02-07 | Becton, Dickinson And Company | Syringe assembly with snap-fit components |
| US5098389A (en) | 1990-06-28 | 1992-03-24 | Becton, Dickinson And Company | Hypodermic needle assembly |
| US5259840A (en) * | 1991-09-03 | 1993-11-09 | Boris Craig R | Locking syringe |
| AU2976895A (en) * | 1994-07-19 | 1996-02-16 | Novo Nordisk A/S | Needle magazine |
| SE9604162D0 (sv) | 1996-11-13 | 1996-11-13 | Astra Ab | Membrane |
| DE19717033A1 (de) * | 1997-04-23 | 1998-11-12 | Schott Glas | Nadelkappe für eine vorfüllbare Einmalspritze |
| US5994700A (en) | 1997-09-04 | 1999-11-30 | Lockheed Martin Energy Research Corporation | FTIR spectrometer with solid-state drive system |
| US5941857A (en) * | 1997-09-12 | 1999-08-24 | Becton Dickinson And Company | Disposable pen needle |
| US5931817A (en) * | 1997-09-12 | 1999-08-03 | Becton Dickinson And Company | Pen needle assembly |
| US5944700A (en) | 1997-09-26 | 1999-08-31 | Becton, Dickinson And Company | Adjustable injection length pen needle |
| DE19856167C1 (de) * | 1998-12-05 | 2000-05-04 | Vetter & Co Apotheker | Nadelschutzanordnung für Spritzen, Karpulen und dergleichen Injektionsinstrumente |
| DE60112440T2 (de) * | 2000-05-31 | 2006-04-20 | Novo Nordisk A/S | Wegwerfbare zweispitzige injektionsnadel |
| US6986760B2 (en) * | 2000-08-02 | 2006-01-17 | Becton, Dickinson And Company | Pen needle and safety shield system |
| US6595960B2 (en) * | 2001-04-12 | 2003-07-22 | Becton, Dickinson And Company | Flexible needle assembly |
| JP4883877B2 (ja) * | 2001-04-13 | 2012-02-22 | ベクトン・ディキンソン・アンド・カンパニー | 皮内針 |
| AU2002333554C1 (en) | 2001-09-12 | 2008-12-11 | Becton, Dickinson And Company | Microneedle-based pen device for drug delivery and method for using same |
| US20070005017A1 (en) * | 2002-02-04 | 2007-01-04 | Becton, Dickinson And Company | Intradermal delivery device with crenellated skin engaging surface geometry |
| CN1756573B (zh) | 2003-01-30 | 2011-06-08 | 贝克顿·迪金森公司 | 具有曲面皮肤接合表面几何图形的皮内输递装置 |
| US8932264B2 (en) * | 2003-08-11 | 2015-01-13 | Becton, Dickinson And Company | Medication delivery pen assembly with needle locking safety shield |
| EP3354308B1 (en) | 2003-08-28 | 2020-11-11 | Becton, Dickinson and Company | Intradermal injection device |
| JP2005152541A (ja) * | 2003-11-21 | 2005-06-16 | Tasuku:Kk | 注射針 |
| US7665605B2 (en) * | 2004-08-14 | 2010-02-23 | Ultimed, Inc. | Sharps container for (I) safe disposal and storage of a single used medical pen needle and/or (II) safe storage and dispensing of a single unused medical pen needle |
| CA2625041C (en) * | 2005-10-13 | 2014-11-25 | Becton, Dickinson And Company | Disposable needle and hub assembly |
| US7842008B2 (en) * | 2005-11-21 | 2010-11-30 | Becton, Dickinson And Company | Intradermal delivery device |
| US8002756B2 (en) | 2006-12-08 | 2011-08-23 | Becton, Dickinson And Company | Method and apparatus for delivering a therapeutic substance through an injection port |
| US7384414B1 (en) * | 2007-01-23 | 2008-06-10 | Becton, Dickinson And Company | Safety pen needle with non-injection end passive safety features |
| CA2639320C (en) * | 2007-09-07 | 2016-10-25 | Becton, Dickinson And Company | Pen-needle assembly for preventing under-torquing and over-torquing of pen-needle |
| CN101945681B (zh) * | 2008-01-15 | 2013-08-07 | 贝克顿·迪金森公司 | 具有笔式针组件的医用注射器 |
| US20090234322A1 (en) * | 2008-03-12 | 2009-09-17 | Ultradent Products, Inc. | Method of dental tissue injection using an array of micro-needles |
| JP5653943B2 (ja) * | 2009-03-03 | 2015-01-14 | ノボ・ノルデイスク・エー/エス | キャップのロック装置 |
| EP2440270B1 (en) * | 2009-06-12 | 2013-04-24 | Novo Nordisk A/S | Drug delivery device with cap functions for needle assembly |
-
2010
- 2010-03-03 CN CN201080018485.7A patent/CN102413858B/zh active Active
- 2010-03-03 EP EP10749302.5A patent/EP2403572B1/en active Active
- 2010-03-03 ES ES19150458T patent/ES2877190T3/es active Active
- 2010-03-03 JP JP2011553096A patent/JP6084772B2/ja active Active
- 2010-03-03 ES ES10749302T patent/ES2718828T3/es active Active
- 2010-03-03 EP EP19150458.8A patent/EP3488885B1/en active Active
- 2010-03-03 WO PCT/US2010/026129 patent/WO2010102067A2/en not_active Ceased
- 2010-03-03 US US13/138,549 patent/US9445838B2/en active Active
- 2010-03-03 EP EP21152686.8A patent/EP3827858A1/en active Pending
-
2014
- 2014-02-04 US US14/172,288 patent/US10441730B2/en active Active
-
2015
- 2015-09-14 JP JP2015181188A patent/JP6272281B2/ja active Active
-
2018
- 2018-12-19 US US16/225,948 patent/US20190117261A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US9445838B2 (en) | 2016-09-20 |
| EP2403572A4 (en) | 2014-07-02 |
| US20190117261A1 (en) | 2019-04-25 |
| JP2016005725A (ja) | 2016-01-14 |
| EP3488885A3 (en) | 2019-08-21 |
| EP2403572A2 (en) | 2012-01-11 |
| EP3488885B1 (en) | 2021-04-28 |
| WO2010102067A2 (en) | 2010-09-10 |
| ES2877190T3 (es) | 2021-11-16 |
| US20120109052A1 (en) | 2012-05-03 |
| CN102413858B (zh) | 2017-03-01 |
| JP2012519546A (ja) | 2012-08-30 |
| WO2010102067A3 (en) | 2011-01-13 |
| US20140188046A1 (en) | 2014-07-03 |
| JP6084772B2 (ja) | 2017-02-22 |
| US10441730B2 (en) | 2019-10-15 |
| EP2403572B1 (en) | 2019-01-16 |
| JP6272281B2 (ja) | 2018-01-31 |
| EP3827858A1 (en) | 2021-06-02 |
| EP3488885A2 (en) | 2019-05-29 |
| CN102413858A (zh) | 2012-04-11 |
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