ES2718203T3 - Métodos y sistemas para la detección de microorganismos - Google Patents

Métodos y sistemas para la detección de microorganismos Download PDF

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Publication number
ES2718203T3
ES2718203T3 ES13751965T ES13751965T ES2718203T3 ES 2718203 T3 ES2718203 T3 ES 2718203T3 ES 13751965 T ES13751965 T ES 13751965T ES 13751965 T ES13751965 T ES 13751965T ES 2718203 T3 ES2718203 T3 ES 2718203T3
Authority
ES
Spain
Prior art keywords
phage
detection
bacteriophage
bacterium
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES13751965T
Other languages
English (en)
Spanish (es)
Inventor
Dwight Lyman Anderson
Andrew J Conrad
Stephen Eric Erickson
Jose S Gil
Ben Barrett Hopkins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labcorp Holdings Inc
Original Assignee
Laboratory Corp of America Holdings
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratory Corp of America Holdings filed Critical Laboratory Corp of America Holdings
Application granted granted Critical
Publication of ES2718203T3 publication Critical patent/ES2718203T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/902Oxidoreductases (1.)
    • G01N2333/90241Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/10Detection of antigens from microorganism in sample from host

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
ES13751965T 2012-02-21 2013-02-21 Métodos y sistemas para la detección de microorganismos Active ES2718203T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261601231P 2012-02-21 2012-02-21
PCT/US2013/027155 WO2013126584A1 (en) 2012-02-21 2013-02-21 Methods and systems for detection of microorganisms

Publications (1)

Publication Number Publication Date
ES2718203T3 true ES2718203T3 (es) 2019-06-28

Family

ID=48982538

Family Applications (1)

Application Number Title Priority Date Filing Date
ES13751965T Active ES2718203T3 (es) 2012-02-21 2013-02-21 Métodos y sistemas para la detección de microorganismos

Country Status (12)

Country Link
US (3) US9482668B2 (https=)
EP (2) EP3536808A1 (https=)
JP (3) JP2015510598A (https=)
CN (2) CN107422115A (https=)
AU (1) AU2013222411B2 (https=)
BR (1) BR112014020512B1 (https=)
CA (1) CA2865308C (https=)
DK (1) DK2817422T3 (https=)
ES (1) ES2718203T3 (https=)
HK (1) HK1245890A1 (https=)
MX (2) MX382157B (https=)
WO (1) WO2013126584A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112014020512B1 (pt) 2012-02-21 2022-07-12 Laboratory Corporation Of America Holdings Métodos e sistemas para a detecção de microorganismos
US10519483B2 (en) 2012-02-21 2019-12-31 Laboratory Corporation Of America Holdings Methods and systems for rapid detection of microorganisms using infectious agents
US10913934B2 (en) 2013-02-21 2021-02-09 Laboratory Corporation Of America Holdings Methods and systems for rapid detection of microorganisms using infectious agents
CN106164259A (zh) * 2014-02-18 2016-11-23 美国控股实验室公司 使用重组噬菌体快速检测微生物的方法和系统
DK3108249T3 (en) * 2014-02-18 2019-03-18 Laboratory Corp America Holdings METHOD AND SYSTEMS FOR QUICK DETECTION OF MICROORGANISMS USING FREE ANTIBODIES
MX2018008778A (es) * 2016-01-18 2018-09-12 Laboratory Corp America Holdings Metodos y sistemas de deteccion rapida de microorganismos utilizando agentes infecciosos.
CN107219361B (zh) * 2016-03-22 2018-12-04 中国石油化工股份有限公司 测量液体样品中细菌含量的装置
US10610104B2 (en) * 2016-12-07 2020-04-07 Progenity, Inc. Gastrointestinal tract detection methods, devices and systems
EP3562953A1 (en) * 2016-12-30 2019-11-06 Quidel Corporation Phage-mediated immunoassay and methods for determining susceptibility of bacteria to antibiotic or probiotic agents
CN106995804A (zh) * 2017-03-20 2017-08-01 海南大学 一种乙酰胆碱酯酶标记的工程化噬菌体快速检测微生物
CN106995805A (zh) * 2017-03-26 2017-08-01 海南大学 一种溶菌酶标记的工程化噬菌体快速检测微生物
WO2019113026A1 (en) 2017-12-04 2019-06-13 John Slater Crosslinked hydrogel compositions for regulating states of encapsulated cancer cells
CA3083263A1 (en) 2018-01-12 2019-07-18 Laboratory Corporation Of America Holdings Methods and systems for the rapid detection of salmonella using infectious agents
US20190324033A1 (en) * 2018-04-20 2019-10-24 Tokitae Llc Phage constructs for detecting bacteria in a fluid, microfluidic devices for use with constructs, and related methods
CA3140294A1 (en) 2019-06-21 2020-12-24 Jose S. GIL Methods for producing mutant bacteriophages for the detection of listeria
JP7781741B2 (ja) 2019-08-26 2025-12-08 ラボラトリー コーポレイション オブ アメリカ ホールディングス 組換え繁殖欠損指標バクテリオファージを使用して微生物を検出するためのデバイスおよび方法
CN115052991B (zh) 2019-09-11 2025-08-12 美国控股实验室公司 使用重组感染因子以表达指示亚基来快速检测微生物的方法和系统
CN111798712B (zh) * 2020-07-15 2021-10-29 周晓庆 噬菌体侵染细菌3d智能模拟方法
US12601740B2 (en) * 2021-03-08 2026-04-14 Cobio Diagnostics Inc. Method and kit for identifying antimicrobial agents and effective concentrations thereof

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US5252496A (en) * 1989-12-18 1993-10-12 Princeton Biomeditech Corporation Carbon black immunochemical label
US6300061B1 (en) * 1992-02-07 2001-10-09 Albert Einstein College Of Medicine Of Yeshiva University Mycobacterial species-specific reporter mycobacteriophages
GB9417593D0 (en) 1994-09-01 1994-10-19 Secr Defence Luciferase labelling method
DE19517940A1 (de) * 1995-05-18 1996-11-21 Merck Patent Gmbh Nachweis von Listerien mittels rekombinanter Bakteriophagen
JP3270722B2 (ja) * 1996-09-27 2002-04-02 オルガノ株式会社 細菌の検出方法及び検出装置
AU2983799A (en) 1998-03-04 1999-09-20 Universal Health-Watch, Inc. Chemiluminescence detection devices
AU2002240877B2 (en) * 2001-01-15 2007-03-29 I.D.M. Immuno-Designed Molecules Ancillary composition for the preparation of committed mature dendritic cells
ES2346424T3 (es) * 2002-04-12 2010-10-15 Colorado School Of Mines Procedimiento de deteccion de bajas concentraciones de una bacteria diana que utiliza fagos para infectar celulas bacterianas diana.
US20050003346A1 (en) * 2002-04-12 2005-01-06 Colorado School Of Mines Apparatus and method for detecting microscopic living organisms using bacteriophage
US20040137430A1 (en) * 2002-10-15 2004-07-15 Regents Of The University Of Minnesota Assays to detect or quantify bacterial or viral pathogens and contaminants
JP4578478B2 (ja) * 2003-04-10 2010-11-10 ケント ボーヒース, バクテリオファージを使用した微生物を検出するための装置および方法
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JP5360997B2 (ja) * 2006-10-20 2013-12-04 アリーア・スカボロー・インコーポレイテツド 病原体を同定するためのアッセイ及び装置
ES2795287T3 (es) 2009-05-01 2020-11-23 Promega Corp Luciferasas de Oplophorus sintéticas con mayor emisión de luz
US20100291541A1 (en) 2009-05-14 2010-11-18 Evoy Stephane Bacteriophage immobilization for biosensors
US9234227B2 (en) 2011-09-26 2016-01-12 Sample6 Technologies, Inc. Recombinant phage and methods
BR112014020512B1 (pt) 2012-02-21 2022-07-12 Laboratory Corporation Of America Holdings Métodos e sistemas para a detecção de microorganismos

Also Published As

Publication number Publication date
JP2015510598A (ja) 2015-04-09
WO2013126584A1 (en) 2013-08-29
JP6636967B2 (ja) 2020-01-29
JP2017074074A (ja) 2017-04-20
AU2013222411A1 (en) 2014-09-18
US20130216997A1 (en) 2013-08-22
EP2817422A1 (en) 2014-12-31
US20170131275A1 (en) 2017-05-11
US20240027445A1 (en) 2024-01-25
BR112014020512B1 (pt) 2022-07-12
JP7048564B2 (ja) 2022-04-05
HK1205762A1 (en) 2015-12-24
US9482668B2 (en) 2016-11-01
CN104245961A (zh) 2014-12-24
MX2014010069A (es) 2015-02-10
CA2865308A1 (en) 2013-08-29
BR112014020512A2 (https=) 2017-06-20
CA2865308C (en) 2022-11-22
EP3536808A1 (en) 2019-09-11
CN107422115A (zh) 2017-12-01
CN104245961B (zh) 2017-05-10
EP2817422A4 (en) 2015-10-28
EP2817422B1 (en) 2019-01-23
JP2020060583A (ja) 2020-04-16
MX354356B (es) 2017-11-21
BR112014020512A8 (pt) 2021-11-23
MX382157B (es) 2025-03-13
AU2013222411B2 (en) 2018-11-15
HK1245890A1 (zh) 2018-08-31
DK2817422T3 (en) 2019-04-15

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