BR112014020512B1 - Métodos e sistemas para a detecção de microorganismos - Google Patents

Métodos e sistemas para a detecção de microorganismos Download PDF

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Publication number
BR112014020512B1
BR112014020512B1 BR112014020512-4A BR112014020512A BR112014020512B1 BR 112014020512 B1 BR112014020512 B1 BR 112014020512B1 BR 112014020512 A BR112014020512 A BR 112014020512A BR 112014020512 B1 BR112014020512 B1 BR 112014020512B1
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BR
Brazil
Prior art keywords
detection
phage
bacteriophage
sample
antibody
Prior art date
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BR112014020512-4A
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English (en)
Portuguese (pt)
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BR112014020512A2 (https=
BR112014020512A8 (pt
Inventor
Dwight Lyman Anderson
Andrew J. Conrad
Stephen Eric Erickson
Jose S. Gil
Ben Barrett Hopkins
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Laboratory Corporation Of America Holdings
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Publication date
Application filed by Laboratory Corporation Of America Holdings filed Critical Laboratory Corporation Of America Holdings
Publication of BR112014020512A2 publication Critical patent/BR112014020512A2/pt
Publication of BR112014020512A8 publication Critical patent/BR112014020512A8/pt
Publication of BR112014020512B1 publication Critical patent/BR112014020512B1/pt

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/902Oxidoreductases (1.)
    • G01N2333/90241Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/10Detection of antigens from microorganism in sample from host

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
BR112014020512-4A 2012-02-21 2013-02-21 Métodos e sistemas para a detecção de microorganismos BR112014020512B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261601231P 2012-02-21 2012-02-21
US61/601,231 2012-02-21
PCT/US2013/027155 WO2013126584A1 (en) 2012-02-21 2013-02-21 Methods and systems for detection of microorganisms

Publications (3)

Publication Number Publication Date
BR112014020512A2 BR112014020512A2 (https=) 2017-06-20
BR112014020512A8 BR112014020512A8 (pt) 2021-11-23
BR112014020512B1 true BR112014020512B1 (pt) 2022-07-12

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Family Applications (1)

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BR112014020512-4A BR112014020512B1 (pt) 2012-02-21 2013-02-21 Métodos e sistemas para a detecção de microorganismos

Country Status (12)

Country Link
US (3) US9482668B2 (https=)
EP (2) EP3536808A1 (https=)
JP (3) JP2015510598A (https=)
CN (2) CN107422115A (https=)
AU (1) AU2013222411B2 (https=)
BR (1) BR112014020512B1 (https=)
CA (1) CA2865308C (https=)
DK (1) DK2817422T3 (https=)
ES (1) ES2718203T3 (https=)
HK (1) HK1245890A1 (https=)
MX (2) MX382157B (https=)
WO (1) WO2013126584A1 (https=)

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Publication number Priority date Publication date Assignee Title
BR112014020512B1 (pt) 2012-02-21 2022-07-12 Laboratory Corporation Of America Holdings Métodos e sistemas para a detecção de microorganismos
US10519483B2 (en) 2012-02-21 2019-12-31 Laboratory Corporation Of America Holdings Methods and systems for rapid detection of microorganisms using infectious agents
US10913934B2 (en) 2013-02-21 2021-02-09 Laboratory Corporation Of America Holdings Methods and systems for rapid detection of microorganisms using infectious agents
CN106164259A (zh) * 2014-02-18 2016-11-23 美国控股实验室公司 使用重组噬菌体快速检测微生物的方法和系统
DK3108249T3 (en) * 2014-02-18 2019-03-18 Laboratory Corp America Holdings METHOD AND SYSTEMS FOR QUICK DETECTION OF MICROORGANISMS USING FREE ANTIBODIES
MX2018008778A (es) * 2016-01-18 2018-09-12 Laboratory Corp America Holdings Metodos y sistemas de deteccion rapida de microorganismos utilizando agentes infecciosos.
CN107219361B (zh) * 2016-03-22 2018-12-04 中国石油化工股份有限公司 测量液体样品中细菌含量的装置
US10610104B2 (en) * 2016-12-07 2020-04-07 Progenity, Inc. Gastrointestinal tract detection methods, devices and systems
EP3562953A1 (en) * 2016-12-30 2019-11-06 Quidel Corporation Phage-mediated immunoassay and methods for determining susceptibility of bacteria to antibiotic or probiotic agents
CN106995804A (zh) * 2017-03-20 2017-08-01 海南大学 一种乙酰胆碱酯酶标记的工程化噬菌体快速检测微生物
CN106995805A (zh) * 2017-03-26 2017-08-01 海南大学 一种溶菌酶标记的工程化噬菌体快速检测微生物
WO2019113026A1 (en) 2017-12-04 2019-06-13 John Slater Crosslinked hydrogel compositions for regulating states of encapsulated cancer cells
CA3083263A1 (en) 2018-01-12 2019-07-18 Laboratory Corporation Of America Holdings Methods and systems for the rapid detection of salmonella using infectious agents
US20190324033A1 (en) * 2018-04-20 2019-10-24 Tokitae Llc Phage constructs for detecting bacteria in a fluid, microfluidic devices for use with constructs, and related methods
CA3140294A1 (en) 2019-06-21 2020-12-24 Jose S. GIL Methods for producing mutant bacteriophages for the detection of listeria
JP7781741B2 (ja) 2019-08-26 2025-12-08 ラボラトリー コーポレイション オブ アメリカ ホールディングス 組換え繁殖欠損指標バクテリオファージを使用して微生物を検出するためのデバイスおよび方法
CN115052991B (zh) 2019-09-11 2025-08-12 美国控股实验室公司 使用重组感染因子以表达指示亚基来快速检测微生物的方法和系统
CN111798712B (zh) * 2020-07-15 2021-10-29 周晓庆 噬菌体侵染细菌3d智能模拟方法
US12601740B2 (en) * 2021-03-08 2026-04-14 Cobio Diagnostics Inc. Method and kit for identifying antimicrobial agents and effective concentrations thereof

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ES2346424T3 (es) * 2002-04-12 2010-10-15 Colorado School Of Mines Procedimiento de deteccion de bajas concentraciones de una bacteria diana que utiliza fagos para infectar celulas bacterianas diana.
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BR112014020512B1 (pt) 2012-02-21 2022-07-12 Laboratory Corporation Of America Holdings Métodos e sistemas para a detecção de microorganismos

Also Published As

Publication number Publication date
JP2015510598A (ja) 2015-04-09
WO2013126584A1 (en) 2013-08-29
JP6636967B2 (ja) 2020-01-29
JP2017074074A (ja) 2017-04-20
AU2013222411A1 (en) 2014-09-18
US20130216997A1 (en) 2013-08-22
EP2817422A1 (en) 2014-12-31
US20170131275A1 (en) 2017-05-11
US20240027445A1 (en) 2024-01-25
JP7048564B2 (ja) 2022-04-05
HK1205762A1 (en) 2015-12-24
ES2718203T3 (es) 2019-06-28
US9482668B2 (en) 2016-11-01
CN104245961A (zh) 2014-12-24
MX2014010069A (es) 2015-02-10
CA2865308A1 (en) 2013-08-29
BR112014020512A2 (https=) 2017-06-20
CA2865308C (en) 2022-11-22
EP3536808A1 (en) 2019-09-11
CN107422115A (zh) 2017-12-01
CN104245961B (zh) 2017-05-10
EP2817422A4 (en) 2015-10-28
EP2817422B1 (en) 2019-01-23
JP2020060583A (ja) 2020-04-16
MX354356B (es) 2017-11-21
BR112014020512A8 (pt) 2021-11-23
MX382157B (es) 2025-03-13
AU2013222411B2 (en) 2018-11-15
HK1245890A1 (zh) 2018-08-31
DK2817422T3 (en) 2019-04-15

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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