CA2865308C - Methods and systems for detection of microorganisms - Google Patents
Methods and systems for detection of microorganisms Download PDFInfo
- Publication number
- CA2865308C CA2865308C CA2865308A CA2865308A CA2865308C CA 2865308 C CA2865308 C CA 2865308C CA 2865308 A CA2865308 A CA 2865308A CA 2865308 A CA2865308 A CA 2865308A CA 2865308 C CA2865308 C CA 2865308C
- Authority
- CA
- Canada
- Prior art keywords
- phage
- bacteriophage
- detection
- protein
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/90241—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/10—Detection of antigens from microorganism in sample from host
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261601231P | 2012-02-21 | 2012-02-21 | |
| US61/601,231 | 2012-02-21 | ||
| PCT/US2013/027155 WO2013126584A1 (en) | 2012-02-21 | 2013-02-21 | Methods and systems for detection of microorganisms |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2865308A1 CA2865308A1 (en) | 2013-08-29 |
| CA2865308C true CA2865308C (en) | 2022-11-22 |
Family
ID=48982538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2865308A Active CA2865308C (en) | 2012-02-21 | 2013-02-21 | Methods and systems for detection of microorganisms |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US9482668B2 (https=) |
| EP (2) | EP3536808A1 (https=) |
| JP (3) | JP2015510598A (https=) |
| CN (2) | CN107422115A (https=) |
| AU (1) | AU2013222411B2 (https=) |
| BR (1) | BR112014020512B1 (https=) |
| CA (1) | CA2865308C (https=) |
| DK (1) | DK2817422T3 (https=) |
| ES (1) | ES2718203T3 (https=) |
| HK (1) | HK1245890A1 (https=) |
| MX (2) | MX382157B (https=) |
| WO (1) | WO2013126584A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112014020512B1 (pt) | 2012-02-21 | 2022-07-12 | Laboratory Corporation Of America Holdings | Métodos e sistemas para a detecção de microorganismos |
| US10519483B2 (en) | 2012-02-21 | 2019-12-31 | Laboratory Corporation Of America Holdings | Methods and systems for rapid detection of microorganisms using infectious agents |
| US10913934B2 (en) | 2013-02-21 | 2021-02-09 | Laboratory Corporation Of America Holdings | Methods and systems for rapid detection of microorganisms using infectious agents |
| CN106164259A (zh) * | 2014-02-18 | 2016-11-23 | 美国控股实验室公司 | 使用重组噬菌体快速检测微生物的方法和系统 |
| DK3108249T3 (en) * | 2014-02-18 | 2019-03-18 | Laboratory Corp America Holdings | METHOD AND SYSTEMS FOR QUICK DETECTION OF MICROORGANISMS USING FREE ANTIBODIES |
| MX2018008778A (es) * | 2016-01-18 | 2018-09-12 | Laboratory Corp America Holdings | Metodos y sistemas de deteccion rapida de microorganismos utilizando agentes infecciosos. |
| CN107219361B (zh) * | 2016-03-22 | 2018-12-04 | 中国石油化工股份有限公司 | 测量液体样品中细菌含量的装置 |
| US10610104B2 (en) * | 2016-12-07 | 2020-04-07 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| EP3562953A1 (en) * | 2016-12-30 | 2019-11-06 | Quidel Corporation | Phage-mediated immunoassay and methods for determining susceptibility of bacteria to antibiotic or probiotic agents |
| CN106995804A (zh) * | 2017-03-20 | 2017-08-01 | 海南大学 | 一种乙酰胆碱酯酶标记的工程化噬菌体快速检测微生物 |
| CN106995805A (zh) * | 2017-03-26 | 2017-08-01 | 海南大学 | 一种溶菌酶标记的工程化噬菌体快速检测微生物 |
| WO2019113026A1 (en) | 2017-12-04 | 2019-06-13 | John Slater | Crosslinked hydrogel compositions for regulating states of encapsulated cancer cells |
| CA3083263A1 (en) | 2018-01-12 | 2019-07-18 | Laboratory Corporation Of America Holdings | Methods and systems for the rapid detection of salmonella using infectious agents |
| US20190324033A1 (en) * | 2018-04-20 | 2019-10-24 | Tokitae Llc | Phage constructs for detecting bacteria in a fluid, microfluidic devices for use with constructs, and related methods |
| CA3140294A1 (en) | 2019-06-21 | 2020-12-24 | Jose S. GIL | Methods for producing mutant bacteriophages for the detection of listeria |
| JP7781741B2 (ja) | 2019-08-26 | 2025-12-08 | ラボラトリー コーポレイション オブ アメリカ ホールディングス | 組換え繁殖欠損指標バクテリオファージを使用して微生物を検出するためのデバイスおよび方法 |
| CN115052991B (zh) | 2019-09-11 | 2025-08-12 | 美国控股实验室公司 | 使用重组感染因子以表达指示亚基来快速检测微生物的方法和系统 |
| CN111798712B (zh) * | 2020-07-15 | 2021-10-29 | 周晓庆 | 噬菌体侵染细菌3d智能模拟方法 |
| US12601740B2 (en) * | 2021-03-08 | 2026-04-14 | Cobio Diagnostics Inc. | Method and kit for identifying antimicrobial agents and effective concentrations thereof |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5252496A (en) * | 1989-12-18 | 1993-10-12 | Princeton Biomeditech Corporation | Carbon black immunochemical label |
| US6300061B1 (en) * | 1992-02-07 | 2001-10-09 | Albert Einstein College Of Medicine Of Yeshiva University | Mycobacterial species-specific reporter mycobacteriophages |
| GB9417593D0 (en) | 1994-09-01 | 1994-10-19 | Secr Defence | Luciferase labelling method |
| DE19517940A1 (de) * | 1995-05-18 | 1996-11-21 | Merck Patent Gmbh | Nachweis von Listerien mittels rekombinanter Bakteriophagen |
| JP3270722B2 (ja) * | 1996-09-27 | 2002-04-02 | オルガノ株式会社 | 細菌の検出方法及び検出装置 |
| AU2983799A (en) | 1998-03-04 | 1999-09-20 | Universal Health-Watch, Inc. | Chemiluminescence detection devices |
| AU2002240877B2 (en) * | 2001-01-15 | 2007-03-29 | I.D.M. Immuno-Designed Molecules | Ancillary composition for the preparation of committed mature dendritic cells |
| ES2346424T3 (es) * | 2002-04-12 | 2010-10-15 | Colorado School Of Mines | Procedimiento de deteccion de bajas concentraciones de una bacteria diana que utiliza fagos para infectar celulas bacterianas diana. |
| US20050003346A1 (en) * | 2002-04-12 | 2005-01-06 | Colorado School Of Mines | Apparatus and method for detecting microscopic living organisms using bacteriophage |
| US20040137430A1 (en) * | 2002-10-15 | 2004-07-15 | Regents Of The University Of Minnesota | Assays to detect or quantify bacterial or viral pathogens and contaminants |
| JP4578478B2 (ja) * | 2003-04-10 | 2010-11-10 | ケント ボーヒース， | バクテリオファージを使用した微生物を検出するための装置および方法 |
| EP1885853A2 (en) * | 2005-05-27 | 2008-02-13 | Guild Associates, Inc. | Biological detection system and method |
| JP5360997B2 (ja) * | 2006-10-20 | 2013-12-04 | アリーア・スカボロー・インコーポレイテツド | 病原体を同定するためのアッセイ及び装置 |
| ES2795287T3 (es) | 2009-05-01 | 2020-11-23 | Promega Corp | Luciferasas de Oplophorus sintéticas con mayor emisión de luz |
| US20100291541A1 (en) | 2009-05-14 | 2010-11-18 | Evoy Stephane | Bacteriophage immobilization for biosensors |
| US9234227B2 (en) | 2011-09-26 | 2016-01-12 | Sample6 Technologies, Inc. | Recombinant phage and methods |
| BR112014020512B1 (pt) | 2012-02-21 | 2022-07-12 | Laboratory Corporation Of America Holdings | Métodos e sistemas para a detecção de microorganismos |
-
2013
- 2013-02-21 BR BR112014020512-4A patent/BR112014020512B1/pt active IP Right Grant
- 2013-02-21 MX MX2017014852A patent/MX382157B/es unknown
- 2013-02-21 CN CN201710263366.1A patent/CN107422115A/zh active Pending
- 2013-02-21 JP JP2014558827A patent/JP2015510598A/ja not_active Withdrawn
- 2013-02-21 EP EP19152164.0A patent/EP3536808A1/en active Pending
- 2013-02-21 CN CN201380019483.3A patent/CN104245961B/zh active Active
- 2013-02-21 US US13/773,339 patent/US9482668B2/en active Active
- 2013-02-21 MX MX2014010069A patent/MX354356B/es active IP Right Grant
- 2013-02-21 DK DK13751965.8T patent/DK2817422T3/en active
- 2013-02-21 WO PCT/US2013/027155 patent/WO2013126584A1/en not_active Ceased
- 2013-02-21 EP EP13751965.8A patent/EP2817422B1/en active Active
- 2013-02-21 CA CA2865308A patent/CA2865308C/en active Active
- 2013-02-21 ES ES13751965T patent/ES2718203T3/es active Active
- 2013-02-21 AU AU2013222411A patent/AU2013222411B2/en active Active
-
2016
- 2016-09-13 US US15/263,619 patent/US20170131275A1/en not_active Abandoned
-
2017
- 2017-02-01 JP JP2017016551A patent/JP6636967B2/ja active Active
-
2018
- 2018-04-25 HK HK18105391.4A patent/HK1245890A1/zh unknown
-
2019
- 2019-12-19 JP JP2019228941A patent/JP7048564B2/ja active Active
-
2023
- 2023-07-27 US US18/360,631 patent/US20240027445A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015510598A (ja) | 2015-04-09 |
| WO2013126584A1 (en) | 2013-08-29 |
| JP6636967B2 (ja) | 2020-01-29 |
| JP2017074074A (ja) | 2017-04-20 |
| AU2013222411A1 (en) | 2014-09-18 |
| US20130216997A1 (en) | 2013-08-22 |
| EP2817422A1 (en) | 2014-12-31 |
| US20170131275A1 (en) | 2017-05-11 |
| US20240027445A1 (en) | 2024-01-25 |
| BR112014020512B1 (pt) | 2022-07-12 |
| JP7048564B2 (ja) | 2022-04-05 |
| HK1205762A1 (en) | 2015-12-24 |
| ES2718203T3 (es) | 2019-06-28 |
| US9482668B2 (en) | 2016-11-01 |
| CN104245961A (zh) | 2014-12-24 |
| MX2014010069A (es) | 2015-02-10 |
| CA2865308A1 (en) | 2013-08-29 |
| BR112014020512A2 (https=) | 2017-06-20 |
| EP3536808A1 (en) | 2019-09-11 |
| CN107422115A (zh) | 2017-12-01 |
| CN104245961B (zh) | 2017-05-10 |
| EP2817422A4 (en) | 2015-10-28 |
| EP2817422B1 (en) | 2019-01-23 |
| JP2020060583A (ja) | 2020-04-16 |
| MX354356B (es) | 2017-11-21 |
| BR112014020512A8 (pt) | 2021-11-23 |
| MX382157B (es) | 2025-03-13 |
| AU2013222411B2 (en) | 2018-11-15 |
| HK1245890A1 (zh) | 2018-08-31 |
| DK2817422T3 (en) | 2019-04-15 |
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| US20200140919A1 (en) | Methods and Systems for Rapid Detection of Microorganisms Using Infectious Agents | |
| CN121379990A (zh) | 使用重组噬菌体快速检测微生物的方法和系统 | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20180111 |
|
| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 12TH ANNIV.) - STANDARD Year of fee payment: 12 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20250214 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT Effective date: 20250214 |