ES2717843T3 - Detección y gestión de coincidencia en el análisis de partículas - Google Patents
Detección y gestión de coincidencia en el análisis de partículas Download PDFInfo
- Publication number
- ES2717843T3 ES2717843T3 ES09819687T ES09819687T ES2717843T3 ES 2717843 T3 ES2717843 T3 ES 2717843T3 ES 09819687 T ES09819687 T ES 09819687T ES 09819687 T ES09819687 T ES 09819687T ES 2717843 T3 ES2717843 T3 ES 2717843T3
- Authority
- ES
- Spain
- Prior art keywords
- particle
- signal
- events
- peak
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000002245 particle Substances 0.000 title claims description 247
- 238000004458 analytical method Methods 0.000 title claims description 25
- 238000001514 detection method Methods 0.000 title claims description 18
- 238000005259 measurement Methods 0.000 claims description 138
- 238000000034 method Methods 0.000 claims description 46
- 239000012530 fluid Substances 0.000 claims description 17
- 238000000149 argon plasma sintering Methods 0.000 claims description 10
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- 238000004590 computer program Methods 0.000 claims 1
- 239000000523 sample Substances 0.000 description 51
- 230000000875 corresponding effect Effects 0.000 description 39
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- 238000010586 diagram Methods 0.000 description 21
- 210000000601 blood cell Anatomy 0.000 description 15
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- 238000007619 statistical method Methods 0.000 description 2
- 238000002604 ultrasonography Methods 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
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- 210000003651 basophil Anatomy 0.000 description 1
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- 238000012937 correction Methods 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1429—Signal processing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1019—Associating Coulter-counter and optical flow cytometer [OFC]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N2015/1461—Coincidence detecting; Circuits therefor
Landscapes
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Signal Processing (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
- Optical Measuring Cells (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/249,473 US8154273B2 (en) | 2008-10-10 | 2008-10-10 | Detecting and handling coincidence in particle analysis |
| PCT/US2009/059363 WO2010042401A1 (en) | 2008-10-10 | 2009-10-02 | Detecting and handling coincidence in particle analysis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2717843T3 true ES2717843T3 (es) | 2019-06-25 |
Family
ID=42098277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09819687T Active ES2717843T3 (es) | 2008-10-10 | 2009-10-02 | Detección y gestión de coincidencia en el análisis de partículas |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8154273B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2350611B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5557842B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN102177427B (cg-RX-API-DMAC7.html) |
| ES (1) | ES2717843T3 (cg-RX-API-DMAC7.html) |
| TR (1) | TR201904506T4 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010042401A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010124202A1 (en) * | 2009-04-24 | 2010-10-28 | Beckman Coulter, Inc. | Method of characterizing particles |
| PT2440941T (pt) * | 2009-06-10 | 2017-07-31 | Cynvenio Biosystems Inc | Métodos e dispositivos de fluxo de bainha |
| BR112012011262A2 (pt) | 2009-11-13 | 2019-09-24 | Beckman Coulter Inc | sistemas e métodos para detectar a presença de um estado biológico usando aglomeração |
| CN103998915B (zh) * | 2011-12-20 | 2016-10-26 | 贝克顿·迪金森公司 | 用于改进分选颗粒的产量的系统和方法 |
| WO2014122873A1 (ja) * | 2013-02-08 | 2014-08-14 | ソニー株式会社 | 微小粒子分析装置及び微小粒子分析システム |
| ES2880609T3 (es) * | 2013-03-14 | 2021-11-25 | Abbott Lab | Métodos para detectar eventos de muestras coincidentes |
| CN106255873B (zh) | 2014-04-10 | 2019-06-04 | 深圳迈瑞生物医疗电子股份有限公司 | 一种进行自动补偿的方法、装置及相应的流式细胞分析仪 |
| WO2016022276A1 (en) * | 2014-08-06 | 2016-02-11 | Beckman Coulter, Inc. | Evaluation of multi-peak events using a flow cytometer |
| JP2016080563A (ja) * | 2014-10-20 | 2016-05-16 | 日本光電工業株式会社 | 分析システム、分析装置 |
| US11029241B2 (en) * | 2015-02-13 | 2021-06-08 | Artium Technologies, Inc. | Enhanced detection through parsing records into signal components |
| FR3034520B1 (fr) | 2015-04-02 | 2020-02-14 | Horiba Abx Sas | Dispositif de comptage de particules |
| CN107367453A (zh) * | 2016-05-13 | 2017-11-21 | 上海纳衍生物科技有限公司 | 一种基于直流电阻抗测量的细胞粒子检测方法 |
| US10725061B2 (en) * | 2017-02-03 | 2020-07-28 | Pentagon Technologies Group, Inc. | Modulated air surface particle detector |
| US10648909B2 (en) | 2017-05-25 | 2020-05-12 | Abbott Laboratories | Methods and systems for assessing flow cell cleanliness |
| JP7124438B2 (ja) * | 2017-06-14 | 2022-08-24 | 株式会社リコー | 細胞保持基材の生成方法、及び装置評価方法 |
| EP3415608B1 (en) | 2017-06-14 | 2022-05-11 | Ricoh Company, Ltd. | Method for producing cell containing base |
| CN108037060B (zh) * | 2018-01-26 | 2019-11-08 | 中国人民解放军总医院 | 粒子计数方法、实现所述方法的粒子计数装置和粒子分析仪 |
| CN112154317B (zh) * | 2018-04-26 | 2024-11-08 | 贝克顿·迪金森公司 | 颗粒分析仪的表征和分选 |
| KR102094373B1 (ko) * | 2018-09-05 | 2020-03-27 | 주식회사 마하테크 | 미세플라스틱 검출장치 |
| JP7437393B2 (ja) | 2018-10-17 | 2024-02-22 | ベクトン・ディキンソン・アンド・カンパニー | 粒子分析器のための適応ソーティング |
| CN109323975B (zh) * | 2018-11-07 | 2021-05-25 | 中国科学院合肥物质科学研究院 | 一种基于回波阈值比较的opc计数校正方法 |
| LT3942278T (lt) * | 2019-03-22 | 2023-09-11 | Precision Planting Llc | Dalelių skaičiavimo aparatas, sistemos ir būdai |
| WO2021133686A1 (en) | 2019-12-27 | 2021-07-01 | Beckman Coulter, Inc. | Sample preparation instrument |
| CN111751864B (zh) * | 2020-06-30 | 2022-07-05 | 北京卫星环境工程研究所 | 粒子探测器指令处理方法和系统 |
| CN112730408B (zh) * | 2020-12-24 | 2024-07-09 | 贝克曼库尔特生物科技（苏州）有限公司 | 液流检测系统和液流检测方法以及分选装置 |
| JP2025508860A (ja) * | 2022-02-24 | 2025-04-10 | ベクトン・ディキンソン・アンド・カンパニー | フローサイトメータデータを同時発生事象の有無について評価するための方法及びシステム |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3949198A (en) | 1972-03-27 | 1976-04-06 | Coulter Electronics, Inc. | Methods and apparatuses for correcting coincidence count inaccuracies in a coulter type of particle analyzer |
| US4021117A (en) * | 1975-08-07 | 1977-05-03 | Hildegard Gohde | Process for automatic counting and measurement of particles |
| HU173092B (hu) | 1976-02-24 | 1979-02-28 | Medicor Muevek | Ehlektroskhema dlja opredelenija chisla eritrocito, srednego ob"joma tel'ca, velichini gematokrita i drugikh parametrov krovi |
| US4263508A (en) * | 1979-04-20 | 1981-04-21 | Research Corporation | Pulse edge measurement for determining particle dimensional characteristics |
| US4981580A (en) * | 1989-05-01 | 1991-01-01 | Coulter Corporation | Coincidence arbitration in a flow cytomery sorting system |
| US5199576A (en) * | 1991-04-05 | 1993-04-06 | University Of Rochester | System for flexibly sorting particles |
| US5286452A (en) * | 1991-05-20 | 1994-02-15 | Sienna Biotech, Inc. | Simultaneous multiple assays |
| EP0698211B1 (en) * | 1993-05-14 | 2003-04-02 | Coulter International Corporation | Reticulocyte analyzing method and apparatus utilizing light scatter techniques |
| US5633945A (en) * | 1994-10-05 | 1997-05-27 | Compucyte Corporation | Accuracy in cell mitosis analysis |
| EP0980516B1 (en) * | 1997-05-05 | 2003-04-02 | ChemoMetec A/S | A method and a system for determination of particles in a liquid sample |
| US5996212A (en) * | 1997-05-23 | 1999-12-07 | U.S. Philips Corporation | Method of manufacturing a body having a structure of layers |
| CA2328408C (en) * | 1998-05-14 | 2005-02-15 | Luminex Corporation | Zero dead time architecture and method for flow cytometer |
| US6592822B1 (en) * | 1998-05-14 | 2003-07-15 | Luminex Corporation | Multi-analyte diagnostic system and computer implemented process for same |
| US6408679B1 (en) * | 2000-02-04 | 2002-06-25 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Bubble measuring instrument and method |
| US6784981B1 (en) * | 2000-06-02 | 2004-08-31 | Idexx Laboratories, Inc. | Flow cytometry-based hematology system |
| US6518747B2 (en) * | 2001-02-16 | 2003-02-11 | Quantum Design, Inc. | Method and apparatus for quantitative determination of accumulations of magnetic particles |
| US6744245B2 (en) * | 2001-07-27 | 2004-06-01 | Coulter International Corp. | Particle count correction method and apparatus |
| US20060015291A1 (en) | 2002-10-18 | 2006-01-19 | Leland Stanford Junior University | Methods and systems for data analysis |
| US20080208511A1 (en) * | 2005-03-07 | 2008-08-28 | Michael Trainer | Methods and apparatus for determining characteristics of particles |
| JP4654070B2 (ja) * | 2004-06-17 | 2011-03-16 | シチズンホールディングス株式会社 | 液晶表示装置及びメモリ性液晶パネルの駆動回路 |
| US7352461B2 (en) | 2004-11-30 | 2008-04-01 | Tokyo Electron Limited | Particle detecting method and storage medium storing program for implementing the method |
| US7417418B1 (en) * | 2005-06-14 | 2008-08-26 | Ayliffe Harold E | Thin film sensor |
| JP2007024844A (ja) * | 2005-07-21 | 2007-02-01 | Sysmex Corp | 血液分析方法及び血液分析装置 |
| US8023592B2 (en) * | 2005-08-24 | 2011-09-20 | Beckman Coulter, Inc. | Method and apparatus for finding center amplitude of particle size-representative pulses produced by aperture based sizing system |
| US7457709B2 (en) * | 2005-12-20 | 2008-11-25 | Beckman Coulter, Inc. | Systems and methods for particle counting |
| US20080015291A1 (en) * | 2006-07-12 | 2008-01-17 | General Electric Company | Flame retardant and scratch resistant thermoplastic polycarbonate compositions |
| EP2062056B1 (en) * | 2006-09-29 | 2019-04-10 | Luminex Corporation | Differentiation of flow cytometry pulses and applications |
| US7739060B2 (en) * | 2006-12-22 | 2010-06-15 | Accuri Cytometers, Inc. | Detection system and user interface for a flow cytometer system |
| US7804594B2 (en) * | 2006-12-29 | 2010-09-28 | Abbott Laboratories, Inc. | Method and apparatus for rapidly counting and identifying biological particles in a flow stream |
| JP4994920B2 (ja) * | 2007-02-01 | 2012-08-08 | シスメックス株式会社 | 検体分析装置 |
-
2008
- 2008-10-10 US US12/249,473 patent/US8154273B2/en active Active
-
2009
- 2009-10-02 EP EP09819687.6A patent/EP2350611B1/en active Active
- 2009-10-02 TR TR2019/04506T patent/TR201904506T4/tr unknown
- 2009-10-02 ES ES09819687T patent/ES2717843T3/es active Active
- 2009-10-02 JP JP2011531085A patent/JP5557842B2/ja active Active
- 2009-10-02 WO PCT/US2009/059363 patent/WO2010042401A1/en not_active Ceased
- 2009-10-02 CN CN200980140598.1A patent/CN102177427B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012505406A (ja) | 2012-03-01 |
| CN102177427B (zh) | 2014-06-18 |
| EP2350611B1 (en) | 2019-02-13 |
| CN102177427A (zh) | 2011-09-07 |
| EP2350611A1 (en) | 2011-08-03 |
| US20100090677A1 (en) | 2010-04-15 |
| JP5557842B2 (ja) | 2014-07-23 |
| WO2010042401A1 (en) | 2010-04-15 |
| TR201904506T4 (tr) | 2019-05-21 |
| US8154273B2 (en) | 2012-04-10 |
| EP2350611A4 (en) | 2015-08-12 |
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