TR201904506T4 - Partikül analizinde çakışmanın saptanması ve kullanılması. - Google Patents

Partikül analizinde çakışmanın saptanması ve kullanılması.

Info

Publication number
TR201904506T4
TR201904506T4 TR2019/04506T TR201904506T TR201904506T4 TR 201904506 T4 TR201904506 T4 TR 201904506T4 TR 2019/04506 T TR2019/04506 T TR 2019/04506T TR 201904506 T TR201904506 T TR 201904506T TR 201904506 T4 TR201904506 T4 TR 201904506T4
Authority
TR
Turkey
Prior art keywords
situations
data
coincidence
peak
points
Prior art date
Application number
TR2019/04506T
Other languages
English (en)
Inventor
w britton Ted
Lu Jiuliu
L Rose Jeffrey
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Publication of TR201904506T4 publication Critical patent/TR201904506T4/tr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1019—Associating Coulter-counter and optical flow cytometer [OFC]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N2015/1461—Coincidence detecting; Circuits therefor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Signal Processing (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Optical Measuring Cells (AREA)

Abstract

Yöntemler ve sistemler, partikül analiz cihazı verilerinden çakışma durumlarını temsil eden verileri büyük ölçüde ortadan kaldırır. Analize yönelik partiküller içeren bir sıvı numunesi hazırlanır. Bir elektrikli veya optik ölçüm cihazı kullanılarak sinyaller algılanır. Her bir sinyal, partikül analiz cihazındaki bir ölçüm bölgesinden akan sıvı numunesinin bir alt numunesinde saptanan durumlara karşılık gelir. Durumlarda çakışma ortaya çıktığı, sinyallerin her birinin bir piki ve birinci ve ikinci noktalarının ölçülmesine bağlı olarak belirlenir. Birinci ve ikinci noktalar, pikin önceden belirlenen bir parçasına karşılık gelen bir sinyal değerine sahiptir. Çakışma durumları ve çakışma olmayan durumlara dayanan sonuç verileri üretilir. Sonuç verileri, daha sonra analiz edilir. Çeşitli örneklerde, yöntem, çeşitli partikül tiplerine uygulanabilir ve hematoloji analiz cihazı ve akış sitometrelerini içeren partikül analiz cihazlarının farklı tiplerinde uygulanabilir.
TR2019/04506T 2008-10-10 2009-10-02 Partikül analizinde çakışmanın saptanması ve kullanılması. TR201904506T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/249,473 US8154273B2 (en) 2008-10-10 2008-10-10 Detecting and handling coincidence in particle analysis

Publications (1)

Publication Number Publication Date
TR201904506T4 true TR201904506T4 (tr) 2019-05-21

Family

ID=42098277

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2019/04506T TR201904506T4 (tr) 2008-10-10 2009-10-02 Partikül analizinde çakışmanın saptanması ve kullanılması.

Country Status (7)

Country Link
US (1) US8154273B2 (tr)
EP (1) EP2350611B1 (tr)
JP (1) JP5557842B2 (tr)
CN (1) CN102177427B (tr)
ES (1) ES2717843T3 (tr)
TR (1) TR201904506T4 (tr)
WO (1) WO2010042401A1 (tr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012524908A (ja) * 2009-04-24 2012-10-18 ベックマン コールター， インコーポレイテッド 粒子を特徴づける方法
PL2440941T3 (pl) * 2009-06-10 2017-10-31 Cynvenio Biosystems Inc Sposoby i urządzenia z przepływem laminarnym
EP2499591A2 (en) 2009-11-13 2012-09-19 Beckman Coulter, Inc. Systems and methods for detecting the presence of a biological status using clustering
US9347933B2 (en) 2011-12-20 2016-05-24 Becton, Dickinson And Company System and method to improve yield of sorted particles
CN104969063B (zh) * 2013-02-08 2018-05-22 索尼公司 微粒分析设备和微粒分析系统
CN105190553B (zh) * 2013-03-14 2019-06-14 雅培实验室 用于检测重合样本事件的方法
CN106255873B (zh) * 2014-04-10 2019-06-04 深圳迈瑞生物医疗电子股份有限公司 一种进行自动补偿的方法、装置及相应的流式细胞分析仪
WO2016022276A1 (en) * 2014-08-06 2016-02-11 Beckman Coulter, Inc. Evaluation of multi-peak events using a flow cytometer
JP2016080563A (ja) * 2014-10-20 2016-05-16 日本光電工業株式会社 分析システム、分析装置
US11029241B2 (en) * 2015-02-13 2021-06-08 Artium Technologies, Inc. Enhanced detection through parsing records into signal components
FR3034520B1 (fr) 2015-04-02 2020-02-14 Horiba Abx Sas Dispositif de comptage de particules
CN107367453A (zh) * 2016-05-13 2017-11-21 上海纳衍生物科技有限公司 一种基于直流电阻抗测量的细胞粒子检测方法
US10725061B2 (en) * 2017-02-03 2020-07-28 Pentagon Technologies Group, Inc. Modulated air surface particle detector
US10648909B2 (en) * 2017-05-25 2020-05-12 Abbott Laboratories Methods and systems for assessing flow cell cleanliness
EP3415608B1 (en) 2017-06-14 2022-05-11 Ricoh Company, Ltd. Method for producing cell containing base
JP7124438B2 (ja) * 2017-06-14 2022-08-24 株式会社リコー 細胞保持基材の生成方法、及び装置評価方法
CN108037060B (zh) * 2018-01-26 2019-11-08 中国人民解放军总医院 粒子计数方法、实现所述方法的粒子计数装置和粒子分析仪
JP7394786B2 (ja) * 2018-04-26 2023-12-08 ベクトン・ディキンソン・アンド・カンパニー 粒子分析器のための特性評価および選別
KR102094373B1 (ko) * 2018-09-05 2020-03-27 주식회사 마하테크 미세플라스틱 검출장치
CN113316713A (zh) * 2018-10-17 2021-08-27 贝克顿·迪金森公司 颗粒分析仪的自适应分选
CN109323975B (zh) * 2018-11-07 2021-05-25 中国科学院合肥物质科学研究院 一种基于回波阈值比较的opc计数校正方法
AU2020245261A1 (en) * 2019-03-22 2021-07-22 Precision Planting Llc Particle counting apparatus, systems and methods
CN111751864B (zh) * 2020-06-30 2022-07-05 北京卫星环境工程研究所 粒子探测器指令处理方法和系统
CN112730408B (zh) * 2020-12-24 2024-07-09 贝克曼库尔特生物科技（苏州）有限公司 液流检测系统和液流检测方法以及分选装置
WO2023163813A1 (en) * 2022-02-24 2023-08-31 Becton, Dickinson And Company Methods and systems for evaluating flow cytometer data for the presence of a coincident event

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3949198A (en) 1972-03-27 1976-04-06 Coulter Electronics, Inc. Methods and apparatuses for correcting coincidence count inaccuracies in a coulter type of particle analyzer
US4021117A (en) * 1975-08-07 1977-05-03 Hildegard Gohde Process for automatic counting and measurement of particles
HU173092B (hu) 1976-02-24 1979-02-28 Medicor Muevek Ehlektroskhema dlja opredelenija chisla eritrocito, srednego ob"joma tel'ca, velichini gematokrita i drugikh parametrov krovi
US4263508A (en) 1979-04-20 1981-04-21 Research Corporation Pulse edge measurement for determining particle dimensional characteristics
US4981580A (en) * 1989-05-01 1991-01-01 Coulter Corporation Coincidence arbitration in a flow cytomery sorting system
US5199576A (en) * 1991-04-05 1993-04-06 University Of Rochester System for flexibly sorting particles
US5286452A (en) * 1991-05-20 1994-02-15 Sienna Biotech, Inc. Simultaneous multiple assays
DE69432410T2 (de) 1993-05-14 2004-03-04 Coulter International Corp., Miami Retikulozyt bestimmungsverfahren und geraet, das lichtstreuungstechniken verwendet
US5633945A (en) * 1994-10-05 1997-05-27 Compucyte Corporation Accuracy in cell mitosis analysis
CA2288996C (en) 1997-05-05 2009-07-21 Chemometec A/S A method and a system for determination of somatic cells in milk
US5996212A (en) * 1997-05-23 1999-12-07 U.S. Philips Corporation Method of manufacturing a body having a structure of layers
CA2331897C (en) 1998-05-14 2008-11-18 Luminex Corporation Multi-analyte diagnostic system and computer implemented process for same
AU4184099A (en) * 1998-05-14 1999-11-29 Luminex Corporation Zero dead time architecture and method for flow cytometer
US6408679B1 (en) * 2000-02-04 2002-06-25 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Bubble measuring instrument and method
US6784981B1 (en) * 2000-06-02 2004-08-31 Idexx Laboratories, Inc. Flow cytometry-based hematology system
US6518747B2 (en) * 2001-02-16 2003-02-11 Quantum Design, Inc. Method and apparatus for quantitative determination of accumulations of magnetic particles
US6744245B2 (en) * 2001-07-27 2004-06-01 Coulter International Corp. Particle count correction method and apparatus
US20060015291A1 (en) 2002-10-18 2006-01-19 Leland Stanford Junior University Methods and systems for data analysis
JP4654070B2 (ja) * 2004-06-17 2011-03-16 シチズンホールディングス株式会社 液晶表示装置及びメモリ性液晶パネルの駆動回路
US7352461B2 (en) 2004-11-30 2008-04-01 Tokyo Electron Limited Particle detecting method and storage medium storing program for implementing the method
US20080204716A1 (en) * 2005-03-07 2008-08-28 Michael Trainer Methods and apparatus for determining characteristics of particles
US7417418B1 (en) * 2005-06-14 2008-08-26 Ayliffe Harold E Thin film sensor
JP2007024844A (ja) * 2005-07-21 2007-02-01 Sysmex Corp 血液分析方法及び血液分析装置
US8023592B2 (en) * 2005-08-24 2011-09-20 Beckman Coulter, Inc. Method and apparatus for finding center amplitude of particle size-representative pulses produced by aperture based sizing system
US7457709B2 (en) * 2005-12-20 2008-11-25 Beckman Coulter, Inc. Systems and methods for particle counting
US20080015291A1 (en) * 2006-07-12 2008-01-17 General Electric Company Flame retardant and scratch resistant thermoplastic polycarbonate compositions
EP2062056B1 (en) 2006-09-29 2019-04-10 Luminex Corporation Differentiation of flow cytometry pulses and applications
US7739060B2 (en) 2006-12-22 2010-06-15 Accuri Cytometers, Inc. Detection system and user interface for a flow cytometer system
US7804594B2 (en) 2006-12-29 2010-09-28 Abbott Laboratories, Inc. Method and apparatus for rapidly counting and identifying biological particles in a flow stream
JP4994920B2 (ja) * 2007-02-01 2012-08-08 シスメックス株式会社 検体分析装置

Also Published As

Publication number Publication date
ES2717843T3 (es) 2019-06-25
US20100090677A1 (en) 2010-04-15
EP2350611A4 (en) 2015-08-12
EP2350611B1 (en) 2019-02-13
JP2012505406A (ja) 2012-03-01
CN102177427B (zh) 2014-06-18
WO2010042401A1 (en) 2010-04-15
JP5557842B2 (ja) 2014-07-23
US8154273B2 (en) 2012-04-10
EP2350611A1 (en) 2011-08-03
CN102177427A (zh) 2011-09-07

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