ES2682279T3 - Mutantes de algas que tienen un fenotipo aclimatado a la luz intensa en compartimentos - Google Patents
Mutantes de algas que tienen un fenotipo aclimatado a la luz intensa en compartimentos Download PDFInfo
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- ES2682279T3 ES2682279T3 ES13860017.6T ES13860017T ES2682279T3 ES 2682279 T3 ES2682279 T3 ES 2682279T3 ES 13860017 T ES13860017 T ES 13860017T ES 2682279 T3 ES2682279 T3 ES 2682279T3
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/825—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving pigment biosynthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/405—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from algae
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/12—Unicellular algae; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/36—Adaptation or attenuation of cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8262—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield involving plant development
- C12N15/8269—Photosynthesis
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
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- Health & Medical Sciences (AREA)
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- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Botany (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Un mutante de algas desrregulado en aclimatación a poca luz, en donde el mutante de algas exhibe al menos una reducción del 20% en clorofila en condiciones de poca luz con respecto a un alga de tipo salvaje de la misma cepa y además en el que el mutante de algas: exhibe un mayor inactivación fotoquímica (qP) a todas las irradiancias fisiológicamente relevantes por encima de 400 μE·m-2·s-1 con respecto a un alga de tipo silvestre de la misma cepa; exhibe un inicio de inactivación no fotoquímica (NPQ) a una intensidad de luz más alta que la intensidad de luz a la cual aparece NPQ en un alga de tipo salvaje de la misma cepa y exhibe un NPQ más bajo en todas las irradiancias fisiológicas por encima de 400 μE·m-2·s-1 que es exhibida por un alga de tipo salvaje de la misma cepa; adicionalmente en el que el mutante está mutado en un gen que codifica un polipéptido que comprende un dominio de dedo de cinc pfam PF02135 TAZ, en el que el polipéptido comprende la proteína LAR1 (SEQ ID Nº: 4), la proteína No-LAR1 (SEQ ID Nº: 8) o un homólogo de la proteína LAR1 (SEQ ID NO: 4) o proteína No-LAR1 (SEQ ID NO: 8) que tiene al menos un 80% de identidad con SEQ ID NO: 4 o SEQ ID NO: 8, con la condición de que el alga no se obtenga exclusivamente por medio de un proceso esencialmente biológico.
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261733956P | 2012-12-06 | 2012-12-06 | |
US201261733956P | 2012-12-06 | ||
US201361810216P | 2013-04-09 | 2013-04-09 | |
US201361810216P | 2013-04-09 | ||
US201361869590P | 2013-08-23 | 2013-08-23 | |
US201361869590P | 2013-08-23 | ||
US201361881342P | 2013-09-23 | 2013-09-23 | |
US201361881342P | 2013-09-23 | ||
PCT/US2013/073741 WO2014089533A2 (en) | 2012-12-06 | 2013-12-06 | Algal mutants having a locked-in high light acclimated phenotype |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2682279T3 true ES2682279T3 (es) | 2018-09-19 |
Family
ID=50884148
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES13860017.6T Active ES2682279T3 (es) | 2012-12-06 | 2013-12-06 | Mutantes de algas que tienen un fenotipo aclimatado a la luz intensa en compartimentos |
ES18178313T Active ES2740648T3 (es) | 2012-12-06 | 2013-12-06 | Mutantes de algas que tienen un fenotipo aclimatado a alta luz bloqueado |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES18178313T Active ES2740648T3 (es) | 2012-12-06 | 2013-12-06 | Mutantes de algas que tienen un fenotipo aclimatado a alta luz bloqueado |
Country Status (11)
Country | Link |
---|---|
US (1) | US9982272B2 (es) |
EP (2) | EP3401388B1 (es) |
CN (2) | CN111321081A (es) |
AU (1) | AU2013355001B2 (es) |
BR (1) | BR112015013013A2 (es) |
CA (2) | CA2892821C (es) |
ES (2) | ES2682279T3 (es) |
IL (2) | IL238721B (es) |
MX (1) | MX358837B (es) |
PT (2) | PT3401388T (es) |
WO (1) | WO2014089533A2 (es) |
Families Citing this family (40)
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EP3613852A3 (en) | 2011-07-22 | 2020-04-22 | President and Fellows of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
US9163284B2 (en) | 2013-08-09 | 2015-10-20 | President And Fellows Of Harvard College | Methods for identifying a target site of a Cas9 nuclease |
US9228207B2 (en) | 2013-09-06 | 2016-01-05 | President And Fellows Of Harvard College | Switchable gRNAs comprising aptamers |
US9737604B2 (en) | 2013-09-06 | 2017-08-22 | President And Fellows Of Harvard College | Use of cationic lipids to deliver CAS9 |
US9322037B2 (en) | 2013-09-06 | 2016-04-26 | President And Fellows Of Harvard College | Cas9-FokI fusion proteins and uses thereof |
AU2014346559B2 (en) | 2013-11-07 | 2020-07-09 | Editas Medicine,Inc. | CRISPR-related methods and compositions with governing gRNAs |
US20150166982A1 (en) | 2013-12-12 | 2015-06-18 | President And Fellows Of Harvard College | Methods for correcting pi3k point mutations |
CN112961868A (zh) | 2013-12-31 | 2021-06-15 | 合成基因组股份有限公司 | 生物质生产率调节剂 |
US10077453B2 (en) | 2014-07-30 | 2018-09-18 | President And Fellows Of Harvard College | CAS9 proteins including ligand-dependent inteins |
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US10544424B2 (en) | 2015-04-15 | 2020-01-28 | Synthetic Genomics, Inc. | Algal chloroplastic SRP54 mutants |
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2013
- 2013-12-06 WO PCT/US2013/073741 patent/WO2014089533A2/en active Application Filing
- 2013-12-06 AU AU2013355001A patent/AU2013355001B2/en not_active Ceased
- 2013-12-06 EP EP18178313.5A patent/EP3401388B1/en active Active
- 2013-12-06 US US14/099,879 patent/US9982272B2/en active Active
- 2013-12-06 CA CA2892821A patent/CA2892821C/en active Active
- 2013-12-06 MX MX2015007262A patent/MX358837B/es active IP Right Grant
- 2013-12-06 CA CA3144049A patent/CA3144049A1/en active Pending
- 2013-12-06 ES ES13860017.6T patent/ES2682279T3/es active Active
- 2013-12-06 PT PT18178313T patent/PT3401388T/pt unknown
- 2013-12-06 CN CN202010198733.6A patent/CN111321081A/zh active Pending
- 2013-12-06 EP EP13860017.6A patent/EP2929029B1/en active Active
- 2013-12-06 PT PT13860017T patent/PT2929029T/pt unknown
- 2013-12-06 BR BR112015013013A patent/BR112015013013A2/pt active Search and Examination
- 2013-12-06 CN CN201380063639.8A patent/CN104837995B/zh active Active
- 2013-12-06 ES ES18178313T patent/ES2740648T3/es active Active
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2015
- 2015-05-10 IL IL238721A patent/IL238721B/en unknown
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2021
- 2021-11-02 IL IL287803A patent/IL287803A/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN104837995A (zh) | 2015-08-12 |
IL238721A0 (en) | 2015-06-30 |
AU2013355001A1 (en) | 2015-06-04 |
BR112015013013A2 (pt) | 2017-09-12 |
CN104837995B (zh) | 2020-03-20 |
CA2892821C (en) | 2022-04-26 |
IL287803A (en) | 2022-01-01 |
MX358837B (es) | 2018-09-05 |
EP3401388A1 (en) | 2018-11-14 |
EP2929029A2 (en) | 2015-10-14 |
EP2929029B1 (en) | 2018-07-25 |
EP2929029A4 (en) | 2016-11-16 |
CA2892821A1 (en) | 2014-06-12 |
PT2929029T (pt) | 2018-10-04 |
WO2014089533A3 (en) | 2014-07-31 |
WO2014089533A2 (en) | 2014-06-12 |
MX2015007262A (es) | 2016-07-18 |
US9982272B2 (en) | 2018-05-29 |
IL238721B (en) | 2021-12-01 |
EP3401388B1 (en) | 2019-07-10 |
US20140220638A1 (en) | 2014-08-07 |
ES2740648T3 (es) | 2020-02-06 |
CA3144049A1 (en) | 2014-06-12 |
AU2013355001B2 (en) | 2017-10-26 |
PT3401388T (pt) | 2019-08-29 |
CN111321081A (zh) | 2020-06-23 |
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