CO6290694A2 - Paramyxovirus eficaz como antitumoral - Google Patents
Paramyxovirus eficaz como antitumoralInfo
- Publication number
- CO6290694A2 CO6290694A2 CO10100021A CO10100021A CO6290694A2 CO 6290694 A2 CO6290694 A2 CO 6290694A2 CO 10100021 A CO10100021 A CO 10100021A CO 10100021 A CO10100021 A CO 10100021A CO 6290694 A2 CO6290694 A2 CO 6290694A2
- Authority
- CO
- Colombia
- Prior art keywords
- virus
- paramyxovirus
- kill
- antitumoral
- effective
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/768—Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se describen paramyxovirus del grupo APMV3, APMV4, APMV5, APMV6, APMV7, APMV8, APMV9, virus Mapuera y virus Fer-de-Lance, los cuales pueden ser usados para la producción de un medicamento para el tratamiento de tumores. El virus tiene una selectividad para matar células tumorales humanas pero no para matar células diferenciadas normales humanas o en proliferación normal humanas con la misma dosis. Por medio de ingeniería genética, el virus se puede modificar de modo tal que se agreguen o reemplacen uno o más genes por los genes homólogos de un paramyxovirus relacionado. Por ese método, la actividad antitumoral del virus quimérico resultante se potencia en comparación con el virus parental.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08075121 | 2008-02-14 | ||
| US2965008P | 2008-02-19 | 2008-02-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6290694A2 true CO6290694A2 (es) | 2011-06-20 |
Family
ID=40955326
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO10100021A CO6290694A2 (es) | 2008-02-14 | 2010-08-13 | Paramyxovirus eficaz como antitumoral |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20090208495A1 (es) |
| EP (1) | EP2252307A2 (es) |
| JP (1) | JP2011512344A (es) |
| KR (1) | KR20100122482A (es) |
| CN (1) | CN101945660A (es) |
| AU (1) | AU2009214066A1 (es) |
| BR (1) | BRPI0908365A2 (es) |
| CA (1) | CA2715136A1 (es) |
| CO (1) | CO6290694A2 (es) |
| CR (1) | CR11631A (es) |
| DO (1) | DOP2010000251A (es) |
| EA (1) | EA201001266A1 (es) |
| EC (1) | ECSP10010401A (es) |
| IL (1) | IL206860A0 (es) |
| MX (1) | MX2010008942A (es) |
| WO (1) | WO2009101149A2 (es) |
| ZA (1) | ZA201006561B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3210622T3 (pl) * | 2009-08-21 | 2021-06-28 | Boehringer Ingelheim Animal Health USA Inc. | Szczepionka z rekombinowanym paramyksowirusem ptaków oraz sposób jej wytwarzania i zastosowania |
| GB0915515D0 (en) * | 2009-09-04 | 2009-10-07 | Ucl Business Plc | Treatment of vasculoproliferative conditions |
| US20130084264A1 (en) * | 2010-06-10 | 2013-04-04 | Carla Christina Schrier | Anti-tumor composition |
| CN108130345A (zh) | 2012-01-24 | 2018-06-08 | 乔治亚大学研究基金公司 | 基于副流感病毒5的疫苗 |
| US10519426B2 (en) | 2013-09-03 | 2019-12-31 | Medimmune Limited | Compositions featuring an attenuated Newcastle disease virus and methods of use for treating neoplasia |
| CN112739359A (zh) * | 2018-07-13 | 2021-04-30 | 西奈山伊坎医学院 | Apmv及其用于治疗癌症的用途 |
| CN115089591B (zh) * | 2022-05-21 | 2024-04-12 | 复旦大学 | 布立尼布在制备抑制肠道病毒71型嗜神经性病毒药物中的应用 |
| CN116970650B (zh) * | 2023-09-22 | 2023-12-08 | 深圳华大生命科学研究院 | 一种包膜蛋白组合、含其的靶向病毒载体及制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA01010393A (es) * | 1999-04-15 | 2004-04-02 | Pro Virus Inc | Tratamiento de neoplasmas con virus. |
| WO2001020989A1 (en) * | 1999-09-22 | 2001-03-29 | Mayo Foundation For Medical Education And Research | Therapeutic methods and compositions using viruses of the recombinant paramyxoviridae family |
| EA013615B1 (ru) * | 2004-11-12 | 2010-06-30 | Байер Шеринг Фарма Акциенгезельшафт | Рекомбинантный онколитический парамиксовирус и его применение |
-
2009
- 2009-02-10 US US12/368,330 patent/US20090208495A1/en not_active Abandoned
- 2009-02-12 WO PCT/EP2009/051659 patent/WO2009101149A2/en active Application Filing
- 2009-02-12 BR BRPI0908365-0A patent/BRPI0908365A2/pt not_active IP Right Cessation
- 2009-02-12 EP EP09709608A patent/EP2252307A2/en not_active Withdrawn
- 2009-02-12 EA EA201001266A patent/EA201001266A1/ru unknown
- 2009-02-12 CA CA2715136A patent/CA2715136A1/en not_active Abandoned
- 2009-02-12 CN CN2009801051826A patent/CN101945660A/zh active Pending
- 2009-02-12 KR KR1020107017980A patent/KR20100122482A/ko not_active Application Discontinuation
- 2009-02-12 MX MX2010008942A patent/MX2010008942A/es not_active Application Discontinuation
- 2009-02-12 AU AU2009214066A patent/AU2009214066A1/en not_active Abandoned
- 2009-02-12 JP JP2010546341A patent/JP2011512344A/ja active Pending
-
2010
- 2010-07-07 IL IL206860A patent/IL206860A0/en unknown
- 2010-08-12 EC EC2010010401A patent/ECSP10010401A/es unknown
- 2010-08-13 CO CO10100021A patent/CO6290694A2/es not_active Application Discontinuation
- 2010-08-13 CR CR11631A patent/CR11631A/es not_active Application Discontinuation
- 2010-08-13 DO DO2010000251A patent/DOP2010000251A/es unknown
- 2010-09-13 ZA ZA2010/06561A patent/ZA201006561B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2715136A1 (en) | 2009-08-20 |
| ECSP10010401A (es) | 2010-09-30 |
| CN101945660A (zh) | 2011-01-12 |
| DOP2010000251A (es) | 2010-08-31 |
| MX2010008942A (es) | 2010-09-07 |
| EP2252307A2 (en) | 2010-11-24 |
| WO2009101149A3 (en) | 2009-11-05 |
| CR11631A (es) | 2010-10-05 |
| US20090208495A1 (en) | 2009-08-20 |
| JP2011512344A (ja) | 2011-04-21 |
| BRPI0908365A2 (pt) | 2015-08-11 |
| AU2009214066A1 (en) | 2009-08-20 |
| KR20100122482A (ko) | 2010-11-22 |
| WO2009101149A2 (en) | 2009-08-20 |
| EA201001266A1 (ru) | 2011-04-29 |
| ZA201006561B (en) | 2012-02-29 |
| IL206860A0 (en) | 2010-12-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Application withdrawn |