ES2647526T3 - Combinación de canagliflozina y probenecid para el tratamiento de la hiperuricemia - Google Patents
Combinación de canagliflozina y probenecid para el tratamiento de la hiperuricemia Download PDFInfo
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- ES2647526T3 ES2647526T3 ES14717246.4T ES14717246T ES2647526T3 ES 2647526 T3 ES2647526 T3 ES 2647526T3 ES 14717246 T ES14717246 T ES 14717246T ES 2647526 T3 ES2647526 T3 ES 2647526T3
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- Prior art keywords
- probenecid
- canagliflozin
- hyperuricemia
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361786738P | 2013-03-15 | 2013-03-15 | |
| US201361786738P | 2013-03-15 | ||
| PCT/US2014/020958 WO2014149789A1 (en) | 2013-03-15 | 2014-03-06 | Combination of canagliflozin and probenecid for the treament of hyperuricemia |
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| ES2647526T3 true ES2647526T3 (es) | 2017-12-22 |
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| ES14717246.4T Active ES2647526T3 (es) | 2013-03-15 | 2014-03-06 | Combinación de canagliflozina y probenecid para el tratamiento de la hiperuricemia |
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| ES (1) | ES2647526T3 (enExample) |
| WO (1) | WO2014149789A1 (enExample) |
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| CN105548378B (zh) * | 2015-12-03 | 2017-12-26 | 上海应用技术学院 | 一种卡格列净α、β异构体的分离方法 |
| WO2019087239A1 (ja) * | 2017-10-30 | 2019-05-09 | 合同会社カルナヘルスサポート | 腎症治療剤 |
| US11547685B2 (en) * | 2017-12-11 | 2023-01-10 | Mayo Foundation For Medical Education And Research | Using probenecid to treat polycystic kidney disease |
| US11554112B2 (en) | 2018-06-07 | 2023-01-17 | Herum Therapeutics International Limited | Combinations of β-lactam compounds and probenecid and uses thereof |
| AU2019392750B2 (en) | 2018-12-06 | 2025-07-10 | Arthrosi Therapeutics, Inc. | Methods for treating or preventing gout or hyperuricemia |
| BR112021010708A2 (pt) | 2018-12-06 | 2021-08-24 | Arthrosi Therapeutics, Inc. | Formas cristalinas de um composto para tratar ou prevenir gota ou hiperuricemia |
| US20200253878A1 (en) | 2019-02-13 | 2020-08-13 | Iterum Therapeutics International Limited | Combinations of beta-lactam compounds and probenecid and uses thereof |
| CN111057049B (zh) * | 2019-11-18 | 2021-06-01 | 杭州华东医药集团新药研究院有限公司 | 一种卡格列净半水化合物的制备方法 |
| EP4164624A4 (en) * | 2020-06-10 | 2024-10-16 | Arthrosi Therapeutics, Inc. | METHODS OF TREATMENT OR PREVENTION OF CHRONIC KIDNEY DISEASE |
| CN112957318A (zh) * | 2021-02-02 | 2021-06-15 | 河北科星药业有限公司 | 丙磺舒溶液及其制备方法 |
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| LT2896397T (lt) | 2003-08-01 | 2017-11-27 | Mitsubishi Tanabe Pharma Corporation | Nauji junginiai, turintys inhibitorinį aktyvumą prieš nuo natrio priklausomą gliukozės transporterį |
| UY30730A1 (es) | 2006-12-04 | 2008-07-03 | Mitsubishi Tanabe Pharma Corp | Forma cristalina del hemihidrato de 1-(b (beta)-d-glucopiranosil) -4-metil-3-[5-(4-fluorofenil) -2-tienilmetil]benceno |
| BRPI0913129A2 (pt) * | 2008-05-22 | 2016-01-05 | Bristol Myers Squibb Co | método para tratamento de hiperuricemia empregando um inibidor de sglt2 e composição contendo o mesmo |
| JP2013523681A (ja) * | 2010-03-30 | 2013-06-17 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｓｇｌｔ２インヒビター及びｐｐａｒ−ガンマアゴニストを含む医薬組成物並びにその使用 |
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2014
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2017
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2019
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Also Published As
| Publication number | Publication date |
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| JP2019089825A (ja) | 2019-06-13 |
| JP2016512817A (ja) | 2016-05-09 |
| EP2968235A1 (en) | 2016-01-20 |
| US20160022632A1 (en) | 2016-01-28 |
| CA2907079C (en) | 2021-06-22 |
| WO2014149789A1 (en) | 2014-09-25 |
| EP2968235B1 (en) | 2017-09-13 |
| US20170368025A1 (en) | 2017-12-28 |
| CA2907079A1 (en) | 2014-09-25 |
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