ES2638868T3 - Emulsión lacrimomimética - Google Patents
Emulsión lacrimomimética Download PDFInfo
- Publication number
- ES2638868T3 ES2638868T3 ES11715556.4T ES11715556T ES2638868T3 ES 2638868 T3 ES2638868 T3 ES 2638868T3 ES 11715556 T ES11715556 T ES 11715556T ES 2638868 T3 ES2638868 T3 ES 2638868T3
- Authority
- ES
- Spain
- Prior art keywords
- emulsion
- phospholipid
- weight
- use according
- lipid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229920000642 polymer Polymers 0.000 claims abstract description 48
- 150000002632 lipids Chemical class 0.000 claims abstract description 33
- 150000003904 phospholipids Chemical class 0.000 claims abstract description 31
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 29
- 235000010445 lecithin Nutrition 0.000 claims abstract description 23
- 239000000787 lecithin Substances 0.000 claims abstract description 23
- 239000003755 preservative agent Substances 0.000 claims abstract description 23
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- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000007979 citrate buffer Substances 0.000 claims abstract description 7
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- 208000003556 Dry Eye Syndromes Diseases 0.000 claims description 18
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- LNAZSHAWQACDHT-XIYTZBAFSA-N (2r,3r,4s,5r,6s)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2s,3r,4s,5r,6r)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6r)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical group CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 claims description 2
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1053030 | 2010-04-21 | ||
| FR1053030A FR2962044B1 (fr) | 2010-04-21 | 2010-04-21 | Emulsion lacrymimetique |
| PCT/EP2011/056447 WO2011131765A2 (fr) | 2010-04-21 | 2011-04-21 | Emulsion lacrymimetique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2638868T3 true ES2638868T3 (es) | 2017-10-24 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES11715556.4T Active ES2638868T3 (es) | 2010-04-21 | 2011-04-21 | Emulsión lacrimomimética |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9801899B2 (enExample) |
| EP (1) | EP2560616B1 (enExample) |
| JP (1) | JP5917490B2 (enExample) |
| DK (1) | DK2560616T3 (enExample) |
| ES (1) | ES2638868T3 (enExample) |
| FR (1) | FR2962044B1 (enExample) |
| HU (1) | HUE034442T2 (enExample) |
| PL (1) | PL2560616T3 (enExample) |
| PT (1) | PT2560616T (enExample) |
| WO (1) | WO2011131765A2 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9278132B2 (en) * | 2012-02-13 | 2016-03-08 | Bausch & Lomb Incorporated | Ophthalmic pharmaceutical compositions and methods of making and using same |
| DE102014203152A1 (de) * | 2014-02-21 | 2015-08-27 | Ursapharm Arzneimittel Gmbh | Mikro- oder Nanoemulsion zur ophthalmologischen Anwendung |
| CN107864623A (zh) | 2015-05-21 | 2018-03-30 | 摩纳哥奥夫塔尔米斯公司 | 作为渗透压保护剂的硫辛酸和牛磺酸的组合 |
| PL3297626T3 (pl) | 2015-05-21 | 2021-12-13 | Ophtalmis | Kompozycja oftalmiczna zawierająca kwas liponowy i kwas hialuronowy |
| ITUB20152542A1 (it) | 2015-07-28 | 2017-01-28 | Altergon Sa | Formulati oftalmici a base di complessi cooperativi di acido ialuronico a basso e alto peso molecolare |
| ES2621877B1 (es) * | 2016-01-04 | 2018-05-04 | Agencia Pública Empresarial Sanitaria Hospital De Poniente | Solución para resección endoscópica |
| US11766421B2 (en) | 2017-09-25 | 2023-09-26 | Surface Ophthalmics, Inc. | Ophthalmic pharmaceutical compositions and methods for treating ocular surface disease |
| JP2022516099A (ja) | 2018-12-27 | 2022-02-24 | サーフィス オフサルミクス，インコーポレイテッド | 眼科用医薬組成物及び癌表面疾患の処置方法 |
| MX388336B (es) * | 2019-09-06 | 2025-03-19 | Sophia Holdings S A De C V | Composicion farmacéutica oftálmica, procesos de preparación y usos de las mismas |
| JPWO2021220712A1 (enExample) * | 2020-04-30 | 2021-11-04 | ||
| EP3919047A1 (en) * | 2020-06-03 | 2021-12-08 | AZAD Pharma AG | Microemulsion for the treatment of dry eye syndrome |
| CN117979951A (zh) | 2021-05-10 | 2024-05-03 | 瑟菲斯眼科股份有限公司 | 一种用于缓解眼部疼痛的硫酸软骨素的用途 |
| US12440510B2 (en) | 2021-05-10 | 2025-10-14 | Surface Ophthalmics, Inc. | Use of chondroitin sulfate for relieving ocular pain |
| JP2023065336A (ja) * | 2021-10-27 | 2023-05-12 | 興和株式会社 | 水中油型乳化組成物 |
| WO2023073925A1 (ja) * | 2021-10-29 | 2023-05-04 | ロート製薬株式会社 | 眼科組成物 |
| JP2023067803A (ja) * | 2021-10-29 | 2023-05-16 | ロート製薬株式会社 | 眼科組成物 |
| FR3151481A1 (fr) | 2023-07-28 | 2025-01-31 | Horus Pharma | Emulsion de type huile dans eau comprenant de l’acide hyaluronique et du dexpanthenol |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2013755C (en) * | 1989-04-05 | 1993-11-30 | Simon Benita | Medicinal emulsions |
| DE4027320C2 (de) | 1990-08-29 | 1993-09-30 | Ursapharm Arzneimittel Gmbh | Fluid-Abgabeeinrichtung für keimfreies Fluid |
| JPH0623256A (ja) * | 1992-06-29 | 1994-02-01 | Nikko Kemikaruzu Kk | レシチンを利用した乳化剤及びｏ／ｗ型エマルション |
| US5744155A (en) * | 1993-08-13 | 1998-04-28 | Friedman; Doron | Bioadhesive emulsion preparations for enhanced drug delivery |
| DE19527132A1 (de) * | 1995-07-25 | 1997-01-30 | Laevosan Gmbh & Co Kg | Ophthalmologische Ozonschutzzusammensetzung |
| JP3687277B2 (ja) * | 1997-06-10 | 2005-08-24 | サンスター株式会社 | 美白化粧料 |
| WO1999016471A1 (en) * | 1997-10-01 | 1999-04-08 | Wakamoto Pharmaceutical Co., Ltd. | O/w emulsion compositions |
| FR2816600B1 (fr) | 2000-11-13 | 2003-03-21 | Michel Faurie | Dispositif distributeur de liquides goutte a goutte |
| DE10161149B4 (de) * | 2001-12-12 | 2007-03-08 | Ursapharm Arzneimittel Gmbh & Co. Kg | Verwendung von Heparin-haltigem Ophthalmikum |
| DE10161110A1 (de) * | 2001-12-12 | 2003-06-26 | Ursapharm Arzneimittel Gmbh | Pharmazeutische Zusammensetzung zur ophthalmologischen und rhinologischen Anwendung |
| CA2498233C (en) * | 2002-09-09 | 2012-08-14 | Santen Pharmaceutical Co., Ltd. | Clear ophthalmic solution comprising latanoprost as active ingredient |
| FR2873358B1 (fr) | 2004-07-20 | 2006-11-10 | Sivel Soc Civ Ile | Dispositif de conditionnement et distribution d'un produit avec flacon filtre sterile muni d'un embout |
| JP5748385B2 (ja) * | 2006-01-13 | 2015-07-15 | 大正製薬株式会社 | Ｏ／ｗ型エマルション水性点眼剤 |
| ITMI20060122A1 (it) * | 2006-01-25 | 2007-07-26 | Polichem Sa | Composizioni per uso vaginale |
| EP1834705B1 (de) | 2006-03-13 | 2011-09-14 | Ing. Erich Pfeiffer GmbH | Austragvorrichtung für ein fliessfähiges Medium |
| ITMO20060252A1 (it) | 2006-08-04 | 2008-02-05 | Mrp Medical Res & Promotion Es | Flacone per il contenimento di fluidi, particolarmente per prodotti farmaceutici o simili |
| JP4385170B2 (ja) * | 2007-07-20 | 2009-12-16 | ロート製薬株式会社 | 乳化組成物 |
| US9034843B2 (en) * | 2007-09-14 | 2015-05-19 | Rohto Pharmaceutical Co., Ltd. | Ophthalmic composition |
| FR2921253B1 (fr) * | 2007-09-26 | 2012-11-16 | Lvmh Rech | Composition cosmetique sous la forme d'une emulsion comprenant une phase aqueuse continue et une phase grasse dispersee et son procede de preparation |
| JP5340954B2 (ja) * | 2007-11-16 | 2013-11-13 | テクノガード株式会社 | 薬物含有脂肪乳剤およびその製造方法 |
| FR2927064B1 (fr) | 2008-02-04 | 2010-03-26 | Rexam Pharma | Embout de distribution de liquide, et ensemble de conditionnement et des distribution de liquide comprenant un tel embout. |
| DE102008027146B4 (de) | 2008-06-02 | 2012-01-19 | Ing. Erich Pfeiffer Gmbh | Austragvorrichtung |
| US20100303915A1 (en) * | 2009-06-02 | 2010-12-02 | Abbott Medical Optics Inc. | Therapeutic opthalmic emulsions |
| WO2011115700A2 (en) * | 2010-03-18 | 2011-09-22 | Precision Dermatology, Inc. | Emollient foams for treatment of seborrheic dermatitis |
| EP2377508B1 (de) * | 2010-04-14 | 2012-10-17 | PM-International AG | Kosmetische O/W-Emulsion zur Hautpflege |
-
2010
- 2010-04-21 FR FR1053030A patent/FR2962044B1/fr active Active
-
2011
- 2011-04-21 JP JP2013505489A patent/JP5917490B2/ja active Active
- 2011-04-21 US US13/642,580 patent/US9801899B2/en active Active
- 2011-04-21 EP EP11715556.4A patent/EP2560616B1/fr active Active
- 2011-04-21 WO PCT/EP2011/056447 patent/WO2011131765A2/fr not_active Ceased
- 2011-04-21 ES ES11715556.4T patent/ES2638868T3/es active Active
- 2011-04-21 DK DK11715556.4T patent/DK2560616T3/en active
- 2011-04-21 PL PL11715556T patent/PL2560616T3/pl unknown
- 2011-04-21 PT PT117155564T patent/PT2560616T/pt unknown
- 2011-04-21 HU HUE11715556A patent/HUE034442T2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP5917490B2 (ja) | 2016-05-18 |
| EP2560616B1 (fr) | 2017-07-19 |
| EP2560616A2 (fr) | 2013-02-27 |
| US20130156867A1 (en) | 2013-06-20 |
| FR2962044B1 (fr) | 2013-02-22 |
| WO2011131765A2 (fr) | 2011-10-27 |
| HUE034442T2 (en) | 2018-02-28 |
| PT2560616T (pt) | 2017-08-30 |
| PL2560616T3 (pl) | 2017-12-29 |
| US9801899B2 (en) | 2017-10-31 |
| DK2560616T3 (en) | 2017-10-16 |
| WO2011131765A3 (fr) | 2012-02-23 |
| JP2013525335A (ja) | 2013-06-20 |
| FR2962044A1 (fr) | 2012-01-06 |
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