ES2628049T3 - Variantes de receptor Fc gamma IIB - Google Patents

Variantes de receptor Fc gamma IIB Download PDF

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Publication number
ES2628049T3
ES2628049T3 ES13798258.3T ES13798258T ES2628049T3 ES 2628049 T3 ES2628049 T3 ES 2628049T3 ES 13798258 T ES13798258 T ES 13798258T ES 2628049 T3 ES2628049 T3 ES 2628049T3
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ES
Spain
Prior art keywords
seq
protein
nucleic acid
expression
vector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES13798258.3T
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English (en)
Spanish (es)
Inventor
Peter Sondermann
Dominik TER MEER
Thomas Pohl
Reno WINTER
Uwe Jacob
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suppremol GmbH
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Suppremol GmbH
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Publication of ES2628049T3 publication Critical patent/ES2628049T3/es
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70535Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
ES13798258.3T 2012-10-30 2013-10-30 Variantes de receptor Fc gamma IIB Active ES2628049T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201213663527 2012-10-30
US13/663,527 US10028998B2 (en) 2012-10-30 2012-10-30 Method for treating an inflammatory disease and/or an autoimmune disease with a soluble FcγRIIb
PCT/EP2013/072741 WO2014068012A1 (en) 2012-10-30 2013-10-30 Fc gamma receptor iib variants

Publications (1)

Publication Number Publication Date
ES2628049T3 true ES2628049T3 (es) 2017-08-01

Family

ID=49679480

Family Applications (1)

Application Number Title Priority Date Filing Date
ES13798258.3T Active ES2628049T3 (es) 2012-10-30 2013-10-30 Variantes de receptor Fc gamma IIB

Country Status (27)

Country Link
US (1) US10028998B2 (OSRAM)
EP (1) EP2914624B1 (OSRAM)
JP (2) JP6423351B2 (OSRAM)
KR (1) KR102170674B1 (OSRAM)
CN (1) CN104918955B (OSRAM)
AU (1) AU2013340831B2 (OSRAM)
BR (1) BR112015008815A2 (OSRAM)
CA (1) CA2887164C (OSRAM)
CL (1) CL2015001127A1 (OSRAM)
DK (1) DK2914624T3 (OSRAM)
EA (1) EA033437B9 (OSRAM)
ES (1) ES2628049T3 (OSRAM)
HR (1) HRP20170894T1 (OSRAM)
HU (1) HUE032786T2 (OSRAM)
IL (1) IL238528A (OSRAM)
IN (1) IN2015DN03206A (OSRAM)
LT (1) LT2914624T (OSRAM)
MX (1) MX359802B (OSRAM)
MY (1) MY173686A (OSRAM)
NZ (1) NZ706884A (OSRAM)
PH (1) PH12015500771B1 (OSRAM)
PL (1) PL2914624T3 (OSRAM)
PT (1) PT2914624T (OSRAM)
RS (1) RS56075B1 (OSRAM)
SG (1) SG11201502749VA (OSRAM)
SI (1) SI2914624T1 (OSRAM)
WO (1) WO2014068012A1 (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10028998B2 (en) 2012-10-30 2018-07-24 Suppremol Gmbh Method for treating an inflammatory disease and/or an autoimmune disease with a soluble FcγRIIb
US10669324B2 (en) 2012-10-30 2020-06-02 Suppremol Gmbh Vector encoding an Fc gamma receptor IIB protein and composition of the encoded protein
EP2796144A1 (en) * 2013-04-26 2014-10-29 SuppreMol GmbH Highly concentrated Formulations of soluble Fc receptors
EP2837637A1 (en) 2013-08-16 2015-02-18 SuppreMol GmbH Novel anti-FcyRIIB IgG-type antibody
BR112016008288A2 (pt) 2013-10-16 2017-09-26 Suppremol Gmbh receptor fc gama solúvel para tratamento de doenças autoimunes bolhosas
JP6710451B2 (ja) * 2016-03-31 2020-06-17 東ソー株式会社 改変型組換えFcγRIIb
CN112423900A (zh) * 2018-06-25 2021-02-26 巴斯夫涂料有限公司 生产优化涂层的方法和使用所述方法可获得的涂层
CN111454914A (zh) * 2019-01-18 2020-07-28 嘉兴安宇生物科技有限公司 一种腺病毒快速纯化方法
CN120769862A (zh) 2022-10-25 2025-10-10 赛斯米克治疗公司 变体IgG FC多肽及其用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE301201T1 (de) 1993-06-07 2005-08-15 Vical Inc Für die gentherapie verwendbare plasmide
AU723325B2 (en) 1995-06-23 2000-08-24 President And Fellows Of Harvard College Transcriptional regulation of genes encoding vascular endothelial growth factor receptors
US6849719B2 (en) 1997-09-17 2005-02-01 Human Genome Sciences, Inc. Antibody to an IL-17 receptor like protein
EP1006183A1 (en) 1998-12-03 2000-06-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Recombinant soluble Fc receptors
DE10157290A1 (de) 2001-11-22 2003-06-05 Max Planck Gesellschaft Pharmazeutische Zusammensetzung enthaltend sFcRgamma IIb oder sFcRgamma III
US20040132101A1 (en) * 2002-09-27 2004-07-08 Xencor Optimized Fc variants and methods for their generation
AU2004293184B2 (en) 2003-11-26 2010-12-16 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Substance binding human IgG Fc receptor IIb
DE602006020333D1 (de) 2005-12-13 2011-04-07 Suppremol Gmbh Multimere fc-rezeptor-polypeptide
EP1870442A1 (en) * 2006-06-19 2007-12-26 DSMIP Assets B.V. Air drying resin and composition
EP1870422A1 (en) 2006-06-20 2007-12-26 SuppreMol GmbH Means for the treatment of diseases characterized by an excessive immune reaction
EP2313105B1 (en) 2008-06-27 2013-07-24 ZymoGenetics, Inc. SOLUBLE HYBRID Fc gamma RECEPTORS AND RELATED METHODS
US10028998B2 (en) 2012-10-30 2018-07-24 Suppremol Gmbh Method for treating an inflammatory disease and/or an autoimmune disease with a soluble FcγRIIb
US10669324B2 (en) 2012-10-30 2020-06-02 Suppremol Gmbh Vector encoding an Fc gamma receptor IIB protein and composition of the encoded protein

Also Published As

Publication number Publication date
IL238528A0 (en) 2015-06-30
MX2015005266A (es) 2015-10-26
NZ706884A (en) 2019-05-31
EA201590845A1 (ru) 2015-08-31
KR102170674B1 (ko) 2020-10-28
PL2914624T3 (pl) 2017-09-29
SG11201502749VA (en) 2015-05-28
CA2887164A1 (en) 2014-05-08
JP6423351B2 (ja) 2018-11-14
MX359802B (es) 2018-10-10
US10028998B2 (en) 2018-07-24
CN104918955B (zh) 2018-10-09
US20140120080A1 (en) 2014-05-01
AU2013340831A1 (en) 2015-04-30
KR20150122621A (ko) 2015-11-02
EP2914624A1 (en) 2015-09-09
DK2914624T3 (en) 2017-06-26
AU2013340831B2 (en) 2017-11-23
JP2018186833A (ja) 2018-11-29
PH12015500771A1 (en) 2015-06-08
BR112015008815A2 (pt) 2017-11-21
SI2914624T1 (sl) 2017-07-31
IL238528A (en) 2017-07-31
RS56075B1 (sr) 2017-10-31
PT2914624T (pt) 2017-06-07
CN104918955A (zh) 2015-09-16
PH12015500771B1 (en) 2018-12-14
EA033437B9 (ru) 2020-03-19
WO2014068012A1 (en) 2014-05-08
HRP20170894T1 (hr) 2017-09-08
EA033437B1 (ru) 2019-10-31
HK1209765A1 (en) 2016-04-08
IN2015DN03206A (OSRAM) 2015-10-02
EP2914624B1 (en) 2017-03-15
MY173686A (en) 2020-02-15
CA2887164C (en) 2020-12-29
LT2914624T (lt) 2017-06-26
HUE032786T2 (en) 2017-10-30
JP2016503289A (ja) 2016-02-04
CL2015001127A1 (es) 2015-12-18

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