ES2624450T3 - Método rápido y sensible para la detección de dianas biológicas - Google Patents

Método rápido y sensible para la detección de dianas biológicas Download PDF

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Publication number
ES2624450T3
ES2624450T3 ES08801362.8T ES08801362T ES2624450T3 ES 2624450 T3 ES2624450 T3 ES 2624450T3 ES 08801362 T ES08801362 T ES 08801362T ES 2624450 T3 ES2624450 T3 ES 2624450T3
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ES
Spain
Prior art keywords
indicator
peroxidase
molecule
detectable
marker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08801362.8T
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English (en)
Spanish (es)
Inventor
Jesper Lohse
Kenneth Heesche Petersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dako Denmark ApS
Original Assignee
Dako Denmark ApS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dako Denmark ApS filed Critical Dako Denmark ApS
Application granted granted Critical
Publication of ES2624450T3 publication Critical patent/ES2624450T3/es
Active legal-status Critical Current
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/908—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ES08801362.8T 2007-09-18 2008-09-16 Método rápido y sensible para la detección de dianas biológicas Active ES2624450T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99420607P 2007-09-18 2007-09-18
US994206P 2007-09-18
PCT/DK2008/000327 WO2009036760A2 (en) 2007-09-18 2008-09-16 A rapid and sensitive method for detection of biological targets

Publications (1)

Publication Number Publication Date
ES2624450T3 true ES2624450T3 (es) 2017-07-14

Family

ID=40121988

Family Applications (1)

Application Number Title Priority Date Filing Date
ES08801362.8T Active ES2624450T3 (es) 2007-09-18 2008-09-16 Método rápido y sensible para la detección de dianas biológicas

Country Status (7)

Country Link
US (2) US9377465B2 (enExample)
EP (1) EP2201058B1 (enExample)
JP (1) JP5639889B2 (enExample)
CN (1) CN101836117B (enExample)
CA (1) CA2698390C (enExample)
ES (1) ES2624450T3 (enExample)
WO (1) WO2009036760A2 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5721639B2 (ja) 2009-02-19 2015-05-20 ダコ・デンマーク・エー/エス 分子標的の検出のための方法と化合物
US9091691B2 (en) 2009-10-20 2015-07-28 Dako Denmark A/S Immunochemical detection of single target entities
EP2591106A1 (en) 2010-07-06 2013-05-15 InteRNA Technologies B.V. Mirna and its diagnostic and therapeutic uses in diseases or conditions associated with melanoma, or in diseases or conditions associated with activated braf pathway
CN103201627B (zh) * 2010-11-08 2016-10-12 丹麦达科有限公司 组织学样品中单个靶标分子的定量
JP6155194B2 (ja) 2010-11-17 2017-06-28 インターペース ダイアグノスティックス リミテッド ライアビリティ カンパニー 良性甲状腺新生物と悪性甲状腺新生物を区別するためのバイオマーカーとしてのmiRNA
CA2817161C (en) 2010-12-06 2019-04-02 Dako Denmark A/S Combined histological stain
CN102565411B (zh) * 2010-12-08 2014-05-28 中国科学院生物物理研究所 示踪磁性纳米颗粒的新方法
CN103597089B (zh) * 2011-04-19 2017-04-12 丹麦达科有限公司 用于酶介导的信号放大的方法
WO2012170206A2 (en) * 2011-06-07 2012-12-13 Diagnostic Innovations, Llc Color-producing diagnostic systems, reagents and methods
CA2853862C (en) 2011-11-08 2020-05-12 Dako Denmark A/S New method for evaluation of target in histological sample
ES2678211T3 (es) 2012-03-27 2018-08-09 Ventana Medical Systems, Inc. Conjugados de señalización y procedimientos de uso
ES2935257T3 (es) 2013-03-15 2023-03-03 Univ Chicago Métodos y composiciones relacionadas con la actividad de las células T
US9890417B2 (en) 2014-11-03 2018-02-13 Agilent Technologies, Inc. Signal amplification of fluorescence in situ hybridization
CN106338423B (zh) 2015-07-10 2020-07-14 三斯坎公司 组织学染色的空间复用
US11360098B2 (en) 2015-09-28 2022-06-14 Quest Diagnostics Investments Llc Amyloid beta detection by mass spectrometry
CN108369235B (zh) * 2015-12-18 2021-11-26 丹麦科达有限公司 生色过氧化物酶底物
CN105987840B (zh) * 2016-06-03 2018-09-28 浙江世纪康大医疗科技股份有限公司 一种柠檬酸抗原修复液
CN105987839B (zh) * 2016-06-03 2018-09-28 浙江世纪康大医疗科技股份有限公司 一种edta-柠檬酸抗原修复液
CN109085338B (zh) * 2018-09-13 2021-07-13 武汉伊莱瑞特生物科技股份有限公司 Ecl底物液及其制备方法和应用
US11237170B2 (en) 2018-12-04 2022-02-01 Aat Bioquest, Inc. Styryl phenols, derivatives and their use in methods of analyte detection
CN120820711B (zh) * 2025-09-16 2025-12-26 中翰盛泰生物技术股份有限公司 检测试剂盒及应用、标志物检测系统、标志物检测方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02500329A (ja) 1987-05-21 1990-02-08 クリエイテイブ・バイオマリキユールズ・インコーポレーテツド ターゲット化多機能蛋白質
DE68927933T2 (de) 1988-09-02 1997-08-14 Dyax Corp Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen
FI903489A7 (fi) 1988-11-11 1990-07-10 Medical Res Council Yhden osan sisältävät ligandit, näitä ligandeja sisältävät reseptorit, menetelmiä niiden valmistamiseksi sekä ligandien ja reseptorien käytt ö
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5196306A (en) 1989-03-29 1993-03-23 E. I. Du Pont De Nemours And Company Method for the detection or quantitation of an analyte using an analyte dependent enzyme activation system
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US5688966A (en) 1996-07-26 1997-11-18 E. I. Du Pont De Nemours And Company Compounds and method for synthesizing sulfoindocyanine dyes
US5863748A (en) 1997-03-14 1999-01-26 New Life Science Products, Inc. p-Hydroxycinnamoyl-containing substrates for an analyte dependent enzyme activation system
IL123451A (en) 1998-02-25 2003-07-06 Ehud Keinan Method and kit for the detection of peroxide-based explosives
US6372937B1 (en) 1998-11-09 2002-04-16 Mark Norman Bobrow Enhanced catalyzed reporter deposition
US6531319B1 (en) * 2000-05-10 2003-03-11 Keshab D. Pant Method of detecting colon cancer
US6670113B2 (en) * 2001-03-30 2003-12-30 Nanoprobes Enzymatic deposition and alteration of metals
US6617125B2 (en) * 2001-06-29 2003-09-09 Perkinelmer Life Sciences, Inc. Compositions for enhanced catalyzed reporter deposition
EP1920072A2 (en) 2005-07-01 2008-05-14 Dako Denmark A/S In situ hybridization detection method
JP5721639B2 (ja) * 2009-02-19 2015-05-20 ダコ・デンマーク・エー/エス 分子標的の検出のための方法と化合物
US9091691B2 (en) * 2009-10-20 2015-07-28 Dako Denmark A/S Immunochemical detection of single target entities

Also Published As

Publication number Publication date
WO2009036760A3 (en) 2009-07-23
JP2010539456A (ja) 2010-12-16
CN101836117B (zh) 2014-07-23
WO2009036760A2 (en) 2009-03-26
EP2201058B1 (en) 2017-04-12
CA2698390C (en) 2018-05-22
US10168335B2 (en) 2019-01-01
EP2201058A2 (en) 2010-06-30
JP5639889B2 (ja) 2014-12-10
US9377465B2 (en) 2016-06-28
US20160370375A1 (en) 2016-12-22
US20100285467A1 (en) 2010-11-11
CA2698390A1 (en) 2009-03-26
CN101836117A (zh) 2010-09-15

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