ES2603379T3 - Compuestos antagonistas de ARN para la modulación de PCSK9 - Google Patents

Compuestos antagonistas de ARN para la modulación de PCSK9 Download PDF

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Publication number
ES2603379T3
ES2603379T3 ES11181596.5T ES11181596T ES2603379T3 ES 2603379 T3 ES2603379 T3 ES 2603379T3 ES 11181596 T ES11181596 T ES 11181596T ES 2603379 T3 ES2603379 T3 ES 2603379T3
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lna
nucleotide
compound
sequence
seq
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Spanish (es)
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Ellen Marie Straarup
Niels Fisker Nielsen
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Roche Innovation Center Copenhagen AS
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Roche Innovation Center Copenhagen AS
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21112—Site-1 protease (3.4.21.112), i.e. subtilisin kexin isozyme-1
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]

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ES11181596.5T 2006-10-09 2007-10-09 Compuestos antagonistas de ARN para la modulación de PCSK9 Active ES2603379T3 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US82873506P 2006-10-09 2006-10-09
US828735P 2006-10-09
US97293207P 2007-09-17 2007-09-17
US972932P 2007-09-17
US97740907P 2007-10-04 2007-10-04
US977409P 2007-10-04

Publications (1)

Publication Number Publication Date
ES2603379T3 true ES2603379T3 (es) 2017-02-27

Family

ID=39125211

Family Applications (1)

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ES11181596.5T Active ES2603379T3 (es) 2006-10-09 2007-10-09 Compuestos antagonistas de ARN para la modulación de PCSK9

Country Status (9)

Country Link
US (1) US20100216864A1 (https=)
EP (2) EP2076597A2 (https=)
JP (1) JP2010505432A (https=)
AU (1) AU2007306361A1 (https=)
CA (1) CA2666191C (https=)
ES (1) ES2603379T3 (https=)
IL (1) IL197668A0 (https=)
MX (1) MX2009003729A (https=)
WO (1) WO2008043753A2 (https=)

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