ES2598653T3 - Moduladores del receptor X del hígado - Google Patents

Moduladores del receptor X del hígado Download PDF

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Publication number
ES2598653T3
ES2598653T3 ES13712102.6T ES13712102T ES2598653T3 ES 2598653 T3 ES2598653 T3 ES 2598653T3 ES 13712102 T ES13712102 T ES 13712102T ES 2598653 T3 ES2598653 T3 ES 2598653T3
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alkyl
nrc
compound
haloalkyl
halogen
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English (en)
Spanish (es)
Inventor
Chengguo DONG
Yi Fan
Katerina Leftheris
Stephen LOTESTA
Suresh B. Singh
Colin Tice
Wei Zhao
Yajun Zheng
Linghang Zhuang
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Vitae Pharmaceuticals LLC
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Vitae Pharmaceuticals LLC
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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  • Chemical Kinetics & Catalysis (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Psychology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
ES13712102.6T 2012-03-16 2013-03-14 Moduladores del receptor X del hígado Active ES2598653T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261612051P 2012-03-16 2012-03-16
US201261612051P 2012-03-16
PCT/US2013/031242 WO2013138565A1 (en) 2012-03-16 2013-03-14 Liver x receptor modulators

Publications (1)

Publication Number Publication Date
ES2598653T3 true ES2598653T3 (es) 2017-01-30

Family

ID=47997957

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Application Number Title Priority Date Filing Date
ES13712102.6T Active ES2598653T3 (es) 2012-03-16 2013-03-14 Moduladores del receptor X del hígado

Country Status (27)

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US (4) US9006244B2 (enExample)
EP (1) EP2825541B1 (enExample)
JP (3) JP6114814B2 (enExample)
KR (1) KR102069912B1 (enExample)
CN (1) CN104203951B (enExample)
AU (1) AU2013232066B2 (enExample)
CA (1) CA2866218C (enExample)
CY (1) CY1118318T1 (enExample)
DK (1) DK2825541T3 (enExample)
EA (1) EA026907B1 (enExample)
ES (1) ES2598653T3 (enExample)
HR (1) HRP20161196T1 (enExample)
HU (1) HUE029402T2 (enExample)
IL (1) IL234265B (enExample)
IN (1) IN2014DN07636A (enExample)
LT (1) LT2825541T (enExample)
ME (1) ME02534B (enExample)
MX (1) MX354818B (enExample)
NZ (1) NZ629122A (enExample)
PL (1) PL2825541T3 (enExample)
PT (1) PT2825541T (enExample)
RS (1) RS55166B1 (enExample)
SG (1) SG11201405328SA (enExample)
SI (1) SI2825541T1 (enExample)
SM (1) SMT201600374B (enExample)
WO (1) WO2013138565A1 (enExample)
ZA (1) ZA201406326B (enExample)

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BR112017002260A2 (pt) * 2014-08-07 2017-11-21 Vitae Pharmaceuticals Inc derivados de piperazina como moduladores do receptor x do fígado
WO2016100619A2 (en) * 2014-12-17 2016-06-23 Rgenix, Inc. Treatment and diagnosis of cancer
CN105017262B (zh) * 2015-07-07 2017-05-03 广东也乐新材料制造有限公司 一种醛基取代多环杂芳烃化合物的合成方法
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EP3713575A4 (en) 2017-11-21 2021-08-25 Rgenix, Inc. POLYMORPHS AND THEIR USES
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