ES2571956T3 - Uso médico de la alfa 1-microglobulina antioxidante y eliminadora de radicales - Google Patents

Uso médico de la alfa 1-microglobulina antioxidante y eliminadora de radicales

Info

Publication number
ES2571956T3
ES2571956T3 ES09777272T ES09777272T ES2571956T3 ES 2571956 T3 ES2571956 T3 ES 2571956T3 ES 09777272 T ES09777272 T ES 09777272T ES 09777272 T ES09777272 T ES 09777272T ES 2571956 T3 ES2571956 T3 ES 2571956T3
Authority
ES
Spain
Prior art keywords
microglobulin
antioxidant
medical use
radical scavenger
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES09777272T
Other languages
English (en)
Spanish (es)
Inventor
Bo Akerström
Stefan Hansson
Martin Lennarth Olsson
Magnus Gram
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guard Therapeutics International AB
Original Assignee
A1M Pharma AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A1M Pharma AB filed Critical A1M Pharma AB
Application granted granted Critical
Publication of ES2571956T3 publication Critical patent/ES2571956T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
ES09777272T 2008-07-18 2009-07-17 Uso médico de la alfa 1-microglobulina antioxidante y eliminadora de radicales Active ES2571956T3 (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US13533808P 2008-07-18 2008-07-18
DKPA200801024 2008-07-18
US18938108P 2008-08-18 2008-08-18
DKPA200801116 2008-08-18
US19750608P 2008-10-27 2008-10-27
DKPA200801478 2008-10-27
PCT/EP2009/005217 WO2010006809A2 (en) 2008-07-18 2009-07-17 Medical use of the radical scavenger and antioxidant alpha-1-microglobulin

Publications (1)

Publication Number Publication Date
ES2571956T3 true ES2571956T3 (es) 2016-05-27

Family

ID=41550762

Family Applications (2)

Application Number Title Priority Date Filing Date
ES09777272T Active ES2571956T3 (es) 2008-07-18 2009-07-17 Uso médico de la alfa 1-microglobulina antioxidante y eliminadora de radicales
ES13172049.2T Active ES2614490T3 (es) 2008-07-18 2009-07-17 Uso médico de la alfa 1-microglobulina antioxidante y eliminadora de radicales

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES13172049.2T Active ES2614490T3 (es) 2008-07-18 2009-07-17 Uso médico de la alfa 1-microglobulina antioxidante y eliminadora de radicales

Country Status (12)

Country Link
US (1) US10350268B2 (enExample)
EP (2) EP2313106B1 (enExample)
JP (3) JP5694928B2 (enExample)
AU (1) AU2009270435B2 (enExample)
CA (1) CA2730531A1 (enExample)
DK (2) DK2638915T3 (enExample)
ES (2) ES2571956T3 (enExample)
HR (2) HRP20160760T1 (enExample)
HU (2) HUE027953T2 (enExample)
PL (2) PL2313106T3 (enExample)
PT (1) PT2638915T (enExample)
WO (1) WO2010006809A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004289252C1 (en) 2003-11-08 2013-06-20 Prothera Biologics, Inc. Preparation and composition of Inter-alpha inhibitor proteins from human plasma for therapeutic use
WO2008098734A1 (en) 2007-02-12 2008-08-21 Stefan Hansson Diagnosis and treatment of preeclampsia
AU2009260822B2 (en) 2008-05-28 2016-09-22 Prothera Biologics, Inc. Preparation and composition of Inter-alpha inhibitor proteins from blood
ES2599034T3 (es) * 2012-09-05 2017-01-31 A1M Pharma Ab Alfa-1-microglobulina para su uso en el tratamiento de enfermedades relacionadas con mitocondrias
WO2014039987A2 (en) 2012-09-09 2014-03-13 Prothera Biologics, Inc. Treatment of disease using inter-alpha inhibitor proteins
WO2015095553A1 (en) 2013-12-20 2015-06-25 Nephrogenesis, Llc Methods and apparatus for kidney dialysis
BR112018068522A2 (pt) * 2016-03-18 2019-01-22 A1M Pharma Ab novas proteínas derivadas de alfa-1-microglobulina e seu uso
EP3512539A4 (en) 2016-09-13 2020-07-29 Prothera Biologics, Inc. METHODS FOR TREATING LUNG DISEASE USING INTER-ALPHA INHIBITOR PROTEINS
WO2018094023A2 (en) * 2016-11-16 2018-05-24 Anand Prasad Cyclic dipeptides and wound healing
BR112019022358A2 (pt) 2017-04-25 2020-05-19 Prothera Biologics Inc métodos para quantificar proteínas inibidoras inter-alfa
CN111511386A (zh) * 2017-11-03 2020-08-07 卫士医疗国际公司 α-1-微球蛋白用于保护骨髓细胞的用途
JP6906807B2 (ja) * 2018-08-31 2021-07-21 一般社団法人クラインシュタイン医工学パースペクティブ 透析装置
WO2024165674A1 (en) 2023-02-08 2024-08-15 Guard Therapeutics International AB Alpha-1-microglobulin derived peptide fragments and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166133A (en) * 1991-04-17 1992-11-24 Cetus Corporation Method for inhibing adhesion of white blood cells to endothelial cells
US6103691A (en) * 1994-03-23 2000-08-15 Tschesche; Harald Utilisation of angiogenin and/or α1 -microglobulin and/or complement factor D in order to inhibit the secretion of proteins
US5910482A (en) 1996-03-19 1999-06-08 Board Of Regents, The University Of Texas System Treatment or prevention of preeclampsia, eclampsia with calcitonin gene related peptide, CGRP analog, progestational agent, nitric oxide source, and cyclooxygenase inhibitor
JP2001348342A (ja) 2001-04-12 2001-12-18 Nippon Zoki Pharmaceut Co Ltd 免疫調整・抗炎症剤
DE10125883A1 (de) 2001-05-28 2002-12-12 Serumwerk Bernburg Ag Arzneimittel enthaltend einen Effektor des Glutathionmetabolismus zusammen mit alpha-Liponsäure im Rahmen der Nierenersatztherapie
DE10237423A1 (de) 2002-08-16 2004-02-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verwendung von LCK-Inhibitoren für die Behandlung von immunologischen Erkrankungen
US20070060512A1 (en) * 2003-03-04 2007-03-15 Homayoun Sadeghi Dipeptidyl-peptidase protected protein
AR045074A1 (es) 2003-07-23 2005-10-12 Applied Research Systems Uso de cd164 soluble en desordenes inflamatorios y autoinmunes
ITMI20032528A1 (it) 2003-12-19 2005-06-20 Francesco Santangelo Uso di cistina o di cisteina per la prevenzione e il
US20060105419A1 (en) 2004-08-16 2006-05-18 Biosite, Inc. Use of a glutathione peroxidase 1 as a marker in cardiovascular conditions
JP2007001922A (ja) 2005-06-23 2007-01-11 Asahi Kasei Pharma Kk 透析患者における腎疾患改善剤、又は機能性食品
US20070292421A1 (en) 2005-07-28 2007-12-20 Feinberg Bruce B Method for treating preeclampsia
US20080133141A1 (en) 2005-12-22 2008-06-05 Frost Stephen J Weighted Scoring Methods and Use Thereof in Screening
WO2008098734A1 (en) * 2007-02-12 2008-08-21 Stefan Hansson Diagnosis and treatment of preeclampsia

Also Published As

Publication number Publication date
EP2638915A1 (en) 2013-09-18
DK2638915T3 (en) 2017-01-30
AU2009270435B2 (en) 2014-10-16
ES2614490T3 (es) 2017-05-31
CA2730531A1 (en) 2010-01-21
HRP20160760T1 (hr) 2016-08-12
PL2638915T3 (pl) 2017-04-28
WO2010006809A2 (en) 2010-01-21
PL2313106T3 (pl) 2016-08-31
JP6406987B2 (ja) 2018-10-17
PT2638915T (pt) 2017-01-10
JP6175478B2 (ja) 2017-08-02
EP2638915B1 (en) 2016-10-19
HUE027953T2 (en) 2017-01-30
JP2012505154A (ja) 2012-03-01
US10350268B2 (en) 2019-07-16
DK2313106T3 (en) 2016-07-25
JP2016102125A (ja) 2016-06-02
AU2009270435A1 (en) 2010-01-21
US20110190208A1 (en) 2011-08-04
EP2313106A2 (en) 2011-04-27
EP2313106B1 (en) 2016-03-30
JP5694928B2 (ja) 2015-04-01
JP2015071620A (ja) 2015-04-16
HUE030274T2 (en) 2017-05-29
HRP20161808T1 (hr) 2017-02-24
WO2010006809A3 (en) 2010-05-27

Similar Documents

Publication Publication Date Title
ES2571956T3 (es) Uso médico de la alfa 1-microglobulina antioxidante y eliminadora de radicales
AR106768A1 (es) Composiciones que comprenden cepas bacterianas
CL2009000533A1 (es) Uso de una variante de defensina parenteral contra la tuberculosis; que comprende una sustitucion d9s en el polipeptido maduro; metodo para eliminar o inhibir mycobacterium in vitro.
MX388380B (es) Composiciones para usarse en el incremento de los niveles de glóbulos rojos y el tratamiento de enfermedad de células falciformes.
CL2012001950A1 (es) Uso de una cepa bacteriana probiotico en la fabricacion de un medicamento o composicion nutricional en humanos o animales para alterar los patrones del sueño
CL2008001038A1 (es) Uso de una composicion que comprende un antagonosta h1, y un compuesto anti-tnf alfa para tratar conjuntivitis alegica o rinitis alergiva en un sujeto humano
CL2008003653A1 (es) Uso de un inhibidor de sglt derivado de glucopiranosilo y un inhibidor de dppiv seleccionado para tratar la diabetes; y composicion farmaceutica.
TW201129938A (en) Personal mapping system
MX338447B (es) Tratamiento para diabetes en pacientes inapropirados para terapia con metformina.
CR20120173A (es) Combinaciones de un inhibidor de pi3k y un inhibidor de mek
CL2011002548A1 (es) Compuestos derivados de resolviina; composicion farmaceutica; uso de la composicion; kit farmaceutico; combinacion farmaceutica; uso de los compuestos en el tratamiento y/o prevencion de una condicion oftalmica.
CL2011000604A1 (es) Compuestos derivados de multiheteroarilo, inhibidores de h-pgds, composicion farmaceutica que los comprende; utiles en el tratamiento de enfermedades inflamatorias y alergicas.
AR068565A1 (es) Composiciones para el tratamiento del cabello
ECSP19072372A (es) Moduladores de la expresión de pcsk9
MX2012001714A (es) Etiqueta colgante y montaje de etiqueta del producto, y metodo de uso.
CL2012000215A1 (es) Composicion farmaceutica que comprende un fucano en combinacion con por lo menos un excipiente, relleno, portador o diluyente; kit que la comprende; y uso para inhibir, prevenir o tratar una enfermedad proliferativa o inflamatoria tal como una adhesion fibrosa, peritonitis, isquemia y rosacea, entre otras.
BR112016021034A8 (pt) composição farmacêutica, uso da mesma e kit
CL2009000803A1 (es) Uso de una variante de igf-1 pegilada para tratar, prevenir un trastorno neuromuscular; metodo para el tratamiento, prevencion y/o demora de un trastorno neuromuscular; composicion que comprende la variante de igf-1 modificada
BR112014000542A2 (pt) composições de peroxidase eosinofílica e métodos de uso das mesmas
MX2022006490A (es) Uso de inhibidores de sglt-2 en el secado de mamiferos no humanos.
BR112017024172A2 (pt) correia cvt
BR112015017427A2 (pt) artigo compreendendo um substrato polimérico e uma camada de polímero de silicone
PE20151494A1 (es) Proceso novedoso para la elaboracion de compuestos para su uso en el tratamiento del cancer
AR060708A1 (es) Procedimiento de regeneracion de toneles o analogos y dispositivo para su realizacion
CL2008001985A1 (es) Uso de compuestos derivados de benzoxazol, benzimidazol y benzotiazol en la prevencion, tratamiento o inhibicion de una afeccion inflamatoria de la piel o afeccion asociada con la disminucion de colageno.