ES2565428T3 - Elemento de ADN que tiene actividad de aumento de expresión de un gen exógeno - Google Patents

Elemento de ADN que tiene actividad de aumento de expresión de un gen exógeno Download PDF

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Publication number
ES2565428T3
ES2565428T3 ES13186031.4T ES13186031T ES2565428T3 ES 2565428 T3 ES2565428 T3 ES 2565428T3 ES 13186031 T ES13186031 T ES 13186031T ES 2565428 T3 ES2565428 T3 ES 2565428T3
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Spain
Prior art keywords
sequence
seq
nucleotides
corresponds
polynucleotide sequence
Prior art date
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Active
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ES13186031.4T
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English (en)
Spanish (es)
Inventor
Daisuke Nishimyia
Tatsuya Inoue
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Daiichi Sankyo Co Ltd
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Daiichi Sankyo Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515—Complete light chain, i.e. VL + CL
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/106—Plasmid DNA for vertebrates
    • C12N2800/107—Plasmid DNA for vertebrates for mammalian
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/46—Vector systems having a special element relevant for transcription elements influencing chromatin structure, e.g. scaffold/matrix attachment region, methylation free island

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES13186031.4T 2010-07-07 2011-07-06 Elemento de ADN que tiene actividad de aumento de expresión de un gen exógeno Active ES2565428T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010154782 2010-07-07
JP2010154782 2010-07-07

Publications (1)

Publication Number Publication Date
ES2565428T3 true ES2565428T3 (es) 2016-04-04

Family

ID=44630215

Family Applications (3)

Application Number Title Priority Date Filing Date
ES13186031.4T Active ES2565428T3 (es) 2010-07-07 2011-07-06 Elemento de ADN que tiene actividad de aumento de expresión de un gen exógeno
ES15188915T Active ES2701091T3 (es) 2010-07-07 2011-07-06 Elemento de ADN que tiene actividad de aumento de expresión de un gen exógeno
ES11743651.9T Active ES2564227T3 (es) 2010-07-07 2011-07-06 Elemento de ADN que tiene actividad de aumento de expresión de un gen exógeno

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES15188915T Active ES2701091T3 (es) 2010-07-07 2011-07-06 Elemento de ADN que tiene actividad de aumento de expresión de un gen exógeno
ES11743651.9T Active ES2564227T3 (es) 2010-07-07 2011-07-06 Elemento de ADN que tiene actividad de aumento de expresión de un gen exógeno

Country Status (14)

Country Link
US (3) US9371543B2 (enExample)
EP (3) EP2591113B1 (enExample)
JP (2) JP5859988B2 (enExample)
KR (3) KR101856927B1 (enExample)
CN (3) CN103080321A (enExample)
AU (3) AU2011274864B2 (enExample)
BR (1) BR112012033780A2 (enExample)
CA (2) CA2916937A1 (enExample)
ES (3) ES2565428T3 (enExample)
IL (1) IL243763A0 (enExample)
RU (1) RU2013104989A (enExample)
SG (4) SG10201705118RA (enExample)
TW (2) TW201604280A (enExample)
WO (1) WO2012005378A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2591113B1 (en) * 2010-07-07 2016-01-20 Daiichi Sankyo Company, Limited Dna element having the activity of enhancing foreign gene expression
CN104066839B (zh) * 2011-11-28 2018-02-16 第一三共株式会社 衍生自人基因的启动子
JP7382138B2 (ja) * 2016-10-03 2023-11-16 第一三共株式会社 Hspa5遺伝子のプロモーター
CN107881174B (zh) * 2017-11-22 2022-06-03 张宝会 一种翻译水平基因表达调控的方法及应用
WO2020034097A1 (en) * 2018-08-14 2020-02-20 Wuxi Biologics (Shanghai) Co., Ltd. Transcriptional regulatory element and its use in enhancing the expression of exogenous protein
US20230192893A1 (en) * 2020-05-11 2023-06-22 Samsung Bioepis Co., Ltd. Human genome-derived polynucleotide and method for producing polypeptide of interest using same
WO2023210607A1 (ja) 2022-04-26 2023-11-02 第一三共株式会社 Eno1遺伝子のプロモーター

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU611263B2 (en) * 1988-02-12 1991-06-06 Commonwealth Scientific And Industrial Research Organisation Pox virus vectors
US20070161003A1 (en) * 2003-09-29 2007-07-12 Morris David W Novel therapeutic targets in cancer
EP2105742A1 (en) * 2008-03-26 2009-09-30 Sanofi-Aventis Use of cathepsin C
JP5344682B2 (ja) * 2008-12-26 2013-11-20 グローブライド株式会社 釣糸ガイド、及び釣糸ガイドの製造方法
EP2591113B1 (en) * 2010-07-07 2016-01-20 Daiichi Sankyo Company, Limited Dna element having the activity of enhancing foreign gene expression
CN104066839B (zh) * 2011-11-28 2018-02-16 第一三共株式会社 衍生自人基因的启动子

Also Published As

Publication number Publication date
US20160333371A1 (en) 2016-11-17
US10407694B2 (en) 2019-09-10
CN103865931B (zh) 2018-10-02
KR101920187B1 (ko) 2018-11-19
US20130171694A1 (en) 2013-07-04
US11060108B2 (en) 2021-07-13
EP3026117B1 (en) 2018-09-12
KR101856927B1 (ko) 2018-05-10
JP2013531967A (ja) 2013-08-15
TW201604280A (zh) 2016-02-01
CA2916937A1 (en) 2012-01-12
CN105950621B (zh) 2019-07-30
SG10201705118RA (en) 2017-07-28
AU2018200686A1 (en) 2018-02-22
AU2011274864B2 (en) 2016-10-06
WO2012005378A3 (en) 2012-04-12
CN103865931A (zh) 2014-06-18
CN105950621A (zh) 2016-09-21
JP2016054741A (ja) 2016-04-21
WO2012005378A2 (en) 2012-01-12
IL243763A0 (en) 2016-04-21
JP5859988B2 (ja) 2016-02-16
KR20180021246A (ko) 2018-02-28
CN103080321A (zh) 2013-05-01
US20190345515A1 (en) 2019-11-14
AU2011274864A1 (en) 2013-02-07
CA2804381A1 (en) 2012-01-12
TWI507523B (zh) 2015-11-11
SG10201505354PA (en) 2015-08-28
EP2684961A1 (en) 2014-01-15
KR20130111514A (ko) 2013-10-10
JP6039048B2 (ja) 2016-12-07
KR20180021247A (ko) 2018-02-28
EP3026117A1 (en) 2016-06-01
CA2804381C (en) 2016-03-22
AU2018200686B2 (en) 2020-02-13
KR101833570B1 (ko) 2018-03-02
BR112012033780A2 (pt) 2016-05-31
TW201207103A (en) 2012-02-16
EP2684961B1 (en) 2016-01-20
AU2016203681A1 (en) 2016-06-23
SG186788A1 (en) 2013-02-28
ES2564227T3 (es) 2016-03-21
EP2591113B1 (en) 2016-01-20
ES2701091T3 (es) 2019-02-20
SG2014009187A (en) 2014-04-28
US9371543B2 (en) 2016-06-21
AU2016203681B2 (en) 2018-04-19
EP2591113A2 (en) 2013-05-15
RU2013104989A (ru) 2014-08-20

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