TW201604280A - 具有增進外來基因表現之dna分子 - Google Patents

具有增進外來基因表現之dna分子 Download PDF

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Publication number
TW201604280A
TW201604280A TW104134850A TW104134850A TW201604280A TW 201604280 A TW201604280 A TW 201604280A TW 104134850 A TW104134850 A TW 104134850A TW 104134850 A TW104134850 A TW 104134850A TW 201604280 A TW201604280 A TW 201604280A
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TW
Taiwan
Prior art keywords
sequence
polynucleotide
polynucleotide sequence
seq
foreign gene
Prior art date
Application number
TW104134850A
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English (en)
Chinese (zh)
Inventor
西宮大祐
井上龍也
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第一三共股份有限公司
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Application filed by 第一三共股份有限公司 filed Critical 第一三共股份有限公司
Publication of TW201604280A publication Critical patent/TW201604280A/zh

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515—Complete light chain, i.e. VL + CL
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/106—Plasmid DNA for vertebrates
    • C12N2800/107—Plasmid DNA for vertebrates for mammalian
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/46—Vector systems having a special element relevant for transcription elements influencing chromatin structure, e.g. scaffold/matrix attachment region, methylation free island

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW104134850A 2010-07-07 2011-07-06 具有增進外來基因表現之dna分子 TW201604280A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2010154782 2010-07-07

Publications (1)

Publication Number Publication Date
TW201604280A true TW201604280A (zh) 2016-02-01

Family

ID=44630215

Family Applications (2)

Application Number Title Priority Date Filing Date
TW104134850A TW201604280A (zh) 2010-07-07 2011-07-06 具有增進外來基因表現之dna分子
TW100123779A TWI507523B (zh) 2010-07-07 2011-07-06 具有增進外來基因表現之dna分子

Family Applications After (1)

Application Number Title Priority Date Filing Date
TW100123779A TWI507523B (zh) 2010-07-07 2011-07-06 具有增進外來基因表現之dna分子

Country Status (14)

Country Link
US (3) US9371543B2 (enExample)
EP (3) EP2591113B1 (enExample)
JP (2) JP5859988B2 (enExample)
KR (3) KR101856927B1 (enExample)
CN (3) CN103080321A (enExample)
AU (3) AU2011274864B2 (enExample)
BR (1) BR112012033780A2 (enExample)
CA (2) CA2916937A1 (enExample)
ES (3) ES2565428T3 (enExample)
IL (1) IL243763A0 (enExample)
RU (1) RU2013104989A (enExample)
SG (4) SG10201705118RA (enExample)
TW (2) TW201604280A (enExample)
WO (1) WO2012005378A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2591113B1 (en) * 2010-07-07 2016-01-20 Daiichi Sankyo Company, Limited Dna element having the activity of enhancing foreign gene expression
CN104066839B (zh) * 2011-11-28 2018-02-16 第一三共株式会社 衍生自人基因的启动子
JP7382138B2 (ja) * 2016-10-03 2023-11-16 第一三共株式会社 Hspa5遺伝子のプロモーター
CN107881174B (zh) * 2017-11-22 2022-06-03 张宝会 一种翻译水平基因表达调控的方法及应用
WO2020034097A1 (en) * 2018-08-14 2020-02-20 Wuxi Biologics (Shanghai) Co., Ltd. Transcriptional regulatory element and its use in enhancing the expression of exogenous protein
US20230192893A1 (en) * 2020-05-11 2023-06-22 Samsung Bioepis Co., Ltd. Human genome-derived polynucleotide and method for producing polypeptide of interest using same
WO2023210607A1 (ja) 2022-04-26 2023-11-02 第一三共株式会社 Eno1遺伝子のプロモーター

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU611263B2 (en) * 1988-02-12 1991-06-06 Commonwealth Scientific And Industrial Research Organisation Pox virus vectors
US20070161003A1 (en) * 2003-09-29 2007-07-12 Morris David W Novel therapeutic targets in cancer
EP2105742A1 (en) * 2008-03-26 2009-09-30 Sanofi-Aventis Use of cathepsin C
JP5344682B2 (ja) * 2008-12-26 2013-11-20 グローブライド株式会社 釣糸ガイド、及び釣糸ガイドの製造方法
EP2591113B1 (en) * 2010-07-07 2016-01-20 Daiichi Sankyo Company, Limited Dna element having the activity of enhancing foreign gene expression
CN104066839B (zh) * 2011-11-28 2018-02-16 第一三共株式会社 衍生自人基因的启动子

Also Published As

Publication number Publication date
US20160333371A1 (en) 2016-11-17
US10407694B2 (en) 2019-09-10
CN103865931B (zh) 2018-10-02
KR101920187B1 (ko) 2018-11-19
US20130171694A1 (en) 2013-07-04
US11060108B2 (en) 2021-07-13
EP3026117B1 (en) 2018-09-12
KR101856927B1 (ko) 2018-05-10
JP2013531967A (ja) 2013-08-15
CA2916937A1 (en) 2012-01-12
CN105950621B (zh) 2019-07-30
SG10201705118RA (en) 2017-07-28
AU2018200686A1 (en) 2018-02-22
AU2011274864B2 (en) 2016-10-06
WO2012005378A3 (en) 2012-04-12
CN103865931A (zh) 2014-06-18
CN105950621A (zh) 2016-09-21
JP2016054741A (ja) 2016-04-21
WO2012005378A2 (en) 2012-01-12
IL243763A0 (en) 2016-04-21
JP5859988B2 (ja) 2016-02-16
KR20180021246A (ko) 2018-02-28
CN103080321A (zh) 2013-05-01
US20190345515A1 (en) 2019-11-14
AU2011274864A1 (en) 2013-02-07
ES2565428T3 (es) 2016-04-04
CA2804381A1 (en) 2012-01-12
TWI507523B (zh) 2015-11-11
SG10201505354PA (en) 2015-08-28
EP2684961A1 (en) 2014-01-15
KR20130111514A (ko) 2013-10-10
JP6039048B2 (ja) 2016-12-07
KR20180021247A (ko) 2018-02-28
EP3026117A1 (en) 2016-06-01
CA2804381C (en) 2016-03-22
AU2018200686B2 (en) 2020-02-13
KR101833570B1 (ko) 2018-03-02
BR112012033780A2 (pt) 2016-05-31
TW201207103A (en) 2012-02-16
EP2684961B1 (en) 2016-01-20
AU2016203681A1 (en) 2016-06-23
SG186788A1 (en) 2013-02-28
ES2564227T3 (es) 2016-03-21
EP2591113B1 (en) 2016-01-20
ES2701091T3 (es) 2019-02-20
SG2014009187A (en) 2014-04-28
US9371543B2 (en) 2016-06-21
AU2016203681B2 (en) 2018-04-19
EP2591113A2 (en) 2013-05-15
RU2013104989A (ru) 2014-08-20

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