ES2563958T3 - Formas cristalinas del ácido 3-[5-(2-fluorofenil)-[1,2,4]-oxadiazol-3-il]-benzoico - Google Patents

Formas cristalinas del ácido 3-[5-(2-fluorofenil)-[1,2,4]-oxadiazol-3-il]-benzoico Download PDF

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ES2563958T3
ES2563958T3 ES07838770.1T ES07838770T ES2563958T3 ES 2563958 T3 ES2563958 T3 ES 2563958T3 ES 07838770 T ES07838770 T ES 07838770T ES 2563958 T3 ES2563958 T3 ES 2563958T3
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disease
crystalline form
premature
codon
carcinoma
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Spanish (es)
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Neil G. Almstead
Peter Seongwoo Hwang
Young-Choon Moon
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PTC Therapeutics Inc
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PTC Therapeutics Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245Oxadiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/061,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
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    • A61P13/00Drugs for disorders of the urinary system
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    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • A61P25/00Drugs for disorders of the nervous system
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    • A61P3/06Antihyperlipidemics
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    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
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    • A61P35/00Antineoplastic agents
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    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A61P5/16Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
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    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Epidemiology (AREA)
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  • Physical Education & Sports Medicine (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Child & Adolescent Psychology (AREA)
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  • Pain & Pain Management (AREA)
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ES07838770.1T 2006-09-25 2007-09-24 Formas cristalinas del ácido 3-[5-(2-fluorofenil)-[1,2,4]-oxadiazol-3-il]-benzoico Active ES2563958T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US84732606P 2006-09-25 2006-09-25
US847326P 2006-09-25
PCT/US2007/020633 WO2008039431A2 (en) 2006-09-25 2007-09-24 Crystalline forms of 3-[5-(2-fhjorophenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid

Publications (1)

Publication Number Publication Date
ES2563958T3 true ES2563958T3 (es) 2016-03-16

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ES12185448.3T Active ES2655338T3 (es) 2006-09-25 2007-09-24 Procedimiento de preparación de formas cristalinas del ácido 3-[5-(2-fluorofenil)-[1,2,4]-oxadiazol-3-il]-benzoico
ES07838770.1T Active ES2563958T3 (es) 2006-09-25 2007-09-24 Formas cristalinas del ácido 3-[5-(2-fluorofenil)-[1,2,4]-oxadiazol-3-il]-benzoico

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ES12185448.3T Active ES2655338T3 (es) 2006-09-25 2007-09-24 Procedimiento de preparación de formas cristalinas del ácido 3-[5-(2-fluorofenil)-[1,2,4]-oxadiazol-3-il]-benzoico

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US (10) US7863456B2 (enExample)
EP (2) EP2076501B8 (enExample)
JP (6) JP5714228B2 (enExample)
KR (1) KR101430144B1 (enExample)
CN (3) CN102382075B (enExample)
AR (2) AR062963A1 (enExample)
AU (1) AU2007300542B2 (enExample)
BR (1) BRPI0717107A2 (enExample)
CA (1) CA2663574C (enExample)
CL (1) CL2007002743A1 (enExample)
DK (1) DK2076501T3 (enExample)
ES (2) ES2655338T3 (enExample)
HK (1) HK1207070A1 (enExample)
HU (1) HUE028503T2 (enExample)
IL (1) IL197717A (enExample)
LT (1) LTC2076501I2 (enExample)
MX (2) MX2009003160A (enExample)
MY (1) MY191209A (enExample)
NO (1) NO341858B1 (enExample)
NZ (1) NZ575795A (enExample)
PE (3) PE20120768A1 (enExample)
PL (2) PL2559689T3 (enExample)
PT (1) PT2076501E (enExample)
SG (2) SG10201609581TA (enExample)
SI (1) SI2076501T1 (enExample)
TW (2) TWI452038B (enExample)
UA (1) UA99600C2 (enExample)
WO (1) WO2008039431A2 (enExample)
ZA (1) ZA200901949B (enExample)

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KR101703137B1 (ko) 2014-05-30 2017-02-07 선문대학교 산학협력단 당 부가 아미노글리코사이드 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 약학적 조성물
CN105461650B (zh) * 2014-09-12 2018-04-13 杭州普晒医药科技有限公司 一种噁二唑化合物的溶剂化物及其制备方法
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WO2019061324A1 (en) 2017-09-29 2019-04-04 Curis Inc. CRYSTALLINE FORMS OF IMMUNOMODULATORS
JP7618445B2 (ja) 2017-10-11 2025-01-21 オーリジーン オンコロジー リミテッド 3-置換1,2,4-オキサジアゾールの結晶形態
CN111372584A (zh) 2017-11-03 2020-07-03 奥瑞基尼探索技术有限公司 Tim-3和pd-1途径的双重抑制剂
EA202090749A1 (ru) 2017-11-06 2020-08-19 Ориджен Дискавери Текнолоджис Лимитед Способы совместной терапии для иммуномодуляции
EA202192767A1 (ru) 2019-04-10 2021-12-29 ПиТиСи ТЕРАПЬЮТИКС, ИНК. Способ лечения опосредуемой нонсенс-мутацией мышечной дистрофии дюшенна у педиатрических пациентов
JP7339900B2 (ja) * 2020-02-26 2023-09-06 新 井上 視野異常診断方法、視野異常診断装置
KR102665711B1 (ko) * 2021-12-21 2024-05-14 재단법인 아산사회복지재단 Ras 활성도를 이용한 신경섬유종증 치료제에 대한 감수성 예측용 바이오마커 조성물 및 Ras 활성 억제제를 포함하는 신경섬유종증 예방 또는 치료용 약학적 조성물
WO2025110781A1 (ko) * 2023-11-24 2025-05-30 재단법인 아산사회복지재단 Ampd3를 포함하는 신경섬유종증 치료제에 대한 감수성 예측용 바이오마커 조성물 및 ampd3 저해제를 포함하는 신경섬유종증 예방 또는 치료용 약학 조성물
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JP7245868B2 (ja) 2023-03-24
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