ES2557477T3 - Nuevos compuestos peptídicos cíclicos - Google Patents
Nuevos compuestos peptídicos cíclicos Download PDFInfo
- Publication number
- ES2557477T3 ES2557477T3 ES06822844.4T ES06822844T ES2557477T3 ES 2557477 T3 ES2557477 T3 ES 2557477T3 ES 06822844 T ES06822844 T ES 06822844T ES 2557477 T3 ES2557477 T3 ES 2557477T3
- Authority
- ES
- Spain
- Prior art keywords
- cyclic peptide
- peptide compounds
- alkyl
- new cyclic
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 108010069514 Cyclic Peptides Proteins 0.000 title abstract 2
- 102000001189 Cyclic Peptides Human genes 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73001105P | 2005-10-26 | 2005-10-26 | |
| US730011P | 2005-10-26 | ||
| US75120405P | 2005-12-19 | 2005-12-19 | |
| US751204P | 2005-12-19 | ||
| PCT/JP2006/321924 WO2007049803A1 (en) | 2005-10-26 | 2006-10-26 | New cyclic peptide compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2557477T3 true ES2557477T3 (es) | 2016-01-26 |
Family
ID=37847219
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES06822844.4T Active ES2557477T3 (es) | 2005-10-26 | 2006-10-26 | Nuevos compuestos peptídicos cíclicos |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US7872097B2 (https=) |
| EP (1) | EP1957518B1 (https=) |
| JP (1) | JP5218051B2 (https=) |
| KR (1) | KR101273681B1 (https=) |
| CN (1) | CN101305019B (https=) |
| AU (1) | AU2006306974B2 (https=) |
| BR (1) | BRPI0617781A2 (https=) |
| CA (1) | CA2623898C (https=) |
| ES (1) | ES2557477T3 (https=) |
| IL (1) | IL190286A0 (https=) |
| NO (1) | NO20082354L (https=) |
| PL (1) | PL1957518T3 (https=) |
| PT (1) | PT1957518E (https=) |
| RU (1) | RU2423377C2 (https=) |
| TW (1) | TWI391403B (https=) |
| WO (1) | WO2007049803A1 (https=) |
| ZA (1) | ZA200803525B (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100017547A (ko) | 2007-05-02 | 2010-02-16 | 아스텔라스세이야쿠 가부시키가이샤 | 신규 시클릭 펩티드 화합물 |
| CN102164947A (zh) * | 2008-09-24 | 2011-08-24 | 安斯泰来制药有限公司 | 肽化合物及其制备方法 |
| KR20110111321A (ko) * | 2009-01-30 | 2011-10-10 | 이난타 파마슈티칼스, 인코포레이티드 | Ｃ형 간염을 예방하거나 치료하기 위한 사이클로스포린 유사체 |
| US8481483B2 (en) | 2009-02-19 | 2013-07-09 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues |
| SG176085A1 (en) * | 2009-05-15 | 2011-12-29 | Stichting Nl Kanker Inst | Lysine compounds and their use in site- and chemoselective modification of peptides and proteins |
| US8349312B2 (en) | 2009-07-09 | 2013-01-08 | Enanta Pharmaceuticals, Inc. | Proline substituted cyclosporin analogues |
| US8367053B2 (en) | 2009-07-09 | 2013-02-05 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues |
| US8685917B2 (en) | 2009-07-09 | 2014-04-01 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues |
| WO2011082289A1 (en) * | 2009-12-30 | 2011-07-07 | Scynexis Inc. | Cyclosporine analogues |
| JP2015529206A (ja) | 2012-08-25 | 2015-10-05 | ザ・ジョンズ・ホプキンス・ユニバーシティ | Ｇａｐｄｈカスケードインヒビター化合物ならびに使用の方法および精神病を含むストレス誘導障害の処置 |
| EP2900684A2 (en) | 2012-09-29 | 2015-08-05 | Novartis AG | Cyclic peptides and use as medicines |
| WO2014085623A1 (en) | 2012-11-28 | 2014-06-05 | Enanta Pharmaceuticals, Inc. | Novel [n-me-4-hydroxyleucine]-9-cyclosporin analogues |
| JP2016538317A (ja) | 2013-08-26 | 2016-12-08 | エナンタ ファーマシューティカルズ インコーポレイテッド | Ｃ型肝炎を防止または治療するための新規シクロスポリン類似体 |
| US9669095B2 (en) | 2014-11-03 | 2017-06-06 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues for preventing or treating hepatitis C infection |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05271267A (ja) * | 1991-04-23 | 1993-10-19 | Fujisawa Pharmaceut Co Ltd | Ｆｒ９０１４５９物質、その製法及び用途 |
| AU759480B2 (en) | 1998-07-01 | 2003-04-17 | Debiopharm S.A. | Novel cyclosporin with improved activity profile |
| AU2001295966A1 (en) * | 2000-10-19 | 2002-04-29 | Fujisawa Pharmaceutical Co. Ltd. | Cell damage inhibitor |
| CN100344648C (zh) * | 2001-10-19 | 2007-10-24 | 伊索泰克尼卡股份有限公司 | 环孢菌素类似物混合物及其在制备免疫调节剂中的用途 |
| GB0320638D0 (en) | 2003-09-03 | 2003-10-01 | Novartis Ag | Organic compounds |
| JP2007015926A (ja) * | 2003-10-06 | 2007-01-25 | Fujisawa Pharmaceut Co Ltd | Ｃ型肝炎治療剤 |
| DK1793844T3 (da) | 2004-10-01 | 2011-03-21 | Debiopharm Sa | Anvendelse af [D-MeAla]3-[EtVal]4-cyklosporin til behandling af hepatitis C-infektion |
| SI1802650T1 (sl) | 2004-10-01 | 2012-03-30 | Scynexis Inc | Eter in tioeter substituirani ciklosporinski derivati za zdravljenje in preventivo pred infekcijami s hepatitisom c |
| ES2314731T3 (es) * | 2004-11-22 | 2009-03-16 | Astellas Pharma Inc. | Analogo de ciclosporina. |
-
2006
- 2006-10-26 PT PT68228444T patent/PT1957518E/pt unknown
- 2006-10-26 US US12/083,551 patent/US7872097B2/en active Active
- 2006-10-26 TW TW095139941A patent/TWI391403B/zh not_active IP Right Cessation
- 2006-10-26 WO PCT/JP2006/321924 patent/WO2007049803A1/en not_active Ceased
- 2006-10-26 ES ES06822844.4T patent/ES2557477T3/es active Active
- 2006-10-26 BR BRPI0617781-6A patent/BRPI0617781A2/pt not_active Application Discontinuation
- 2006-10-26 PL PL06822844T patent/PL1957518T3/pl unknown
- 2006-10-26 CA CA2623898A patent/CA2623898C/en not_active Expired - Fee Related
- 2006-10-26 KR KR1020087012431A patent/KR101273681B1/ko not_active Expired - Fee Related
- 2006-10-26 AU AU2006306974A patent/AU2006306974B2/en not_active Ceased
- 2006-10-26 JP JP2008521463A patent/JP5218051B2/ja not_active Expired - Fee Related
- 2006-10-26 RU RU2008116674/04A patent/RU2423377C2/ru not_active IP Right Cessation
- 2006-10-26 CN CN2006800390294A patent/CN101305019B/zh not_active Expired - Fee Related
- 2006-10-26 EP EP06822844.4A patent/EP1957518B1/en active Active
-
2008
- 2008-03-19 IL IL190286A patent/IL190286A0/en unknown
- 2008-04-22 ZA ZA2008/03525A patent/ZA200803525B/en unknown
- 2008-05-23 NO NO20082354A patent/NO20082354L/no not_active Application Discontinuation
-
2010
- 2010-07-21 US US12/840,488 patent/US8252895B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009513562A (ja) | 2009-04-02 |
| US8252895B2 (en) | 2012-08-28 |
| PL1957518T3 (pl) | 2016-07-29 |
| RU2008116674A (ru) | 2009-10-27 |
| CN101305019A (zh) | 2008-11-12 |
| KR101273681B1 (ko) | 2013-06-25 |
| TW200732351A (en) | 2007-09-01 |
| CN101305019B (zh) | 2012-12-12 |
| NO20082354L (no) | 2008-07-01 |
| US7872097B2 (en) | 2011-01-18 |
| IL190286A0 (en) | 2011-08-01 |
| EP1957518A1 (en) | 2008-08-20 |
| RU2423377C2 (ru) | 2011-07-10 |
| CA2623898C (en) | 2013-12-24 |
| EP1957518B1 (en) | 2015-12-09 |
| WO2007049803A1 (en) | 2007-05-03 |
| AU2006306974A1 (en) | 2007-05-03 |
| AU2006306974B2 (en) | 2011-09-22 |
| US20100286033A1 (en) | 2010-11-11 |
| US20090170755A1 (en) | 2009-07-02 |
| PT1957518E (pt) | 2016-02-26 |
| CA2623898A1 (en) | 2007-05-03 |
| JP5218051B2 (ja) | 2013-06-26 |
| KR20080065297A (ko) | 2008-07-11 |
| BRPI0617781A2 (pt) | 2011-08-09 |
| ZA200803525B (en) | 2009-08-26 |
| TWI391403B (zh) | 2013-04-01 |
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