ES2557477T3 - Nuevos compuestos peptídicos cíclicos - Google Patents

Nuevos compuestos peptídicos cíclicos Download PDF

Info

Publication number
ES2557477T3
ES2557477T3 ES06822844.4T ES06822844T ES2557477T3 ES 2557477 T3 ES2557477 T3 ES 2557477T3 ES 06822844 T ES06822844 T ES 06822844T ES 2557477 T3 ES2557477 T3 ES 2557477T3
Authority
ES
Spain
Prior art keywords
cyclic peptide
peptide compounds
alkyl
new cyclic
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES06822844.4T
Other languages
English (en)
Spanish (es)
Inventor
Masahiro Neya
Seiji Yoshimura
Kazunori Kamijyo
Takuya Makino
Minoru Yasuda
Toshio Yamanaka
Eisaku Tsujii
Yukiko Yamagishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Application granted granted Critical
Publication of ES2557477T3 publication Critical patent/ES2557477T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ES06822844.4T 2005-10-26 2006-10-26 Nuevos compuestos peptídicos cíclicos Active ES2557477T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US73001105P 2005-10-26 2005-10-26
US730011P 2005-10-26
US75120405P 2005-12-19 2005-12-19
US751204P 2005-12-19
PCT/JP2006/321924 WO2007049803A1 (en) 2005-10-26 2006-10-26 New cyclic peptide compounds

Publications (1)

Publication Number Publication Date
ES2557477T3 true ES2557477T3 (es) 2016-01-26

Family

ID=37847219

Family Applications (1)

Application Number Title Priority Date Filing Date
ES06822844.4T Active ES2557477T3 (es) 2005-10-26 2006-10-26 Nuevos compuestos peptídicos cíclicos

Country Status (17)

Country Link
US (2) US7872097B2 (enExample)
EP (1) EP1957518B1 (enExample)
JP (1) JP5218051B2 (enExample)
KR (1) KR101273681B1 (enExample)
CN (1) CN101305019B (enExample)
AU (1) AU2006306974B2 (enExample)
BR (1) BRPI0617781A2 (enExample)
CA (1) CA2623898C (enExample)
ES (1) ES2557477T3 (enExample)
IL (1) IL190286A0 (enExample)
NO (1) NO20082354L (enExample)
PL (1) PL1957518T3 (enExample)
PT (1) PT1957518E (enExample)
RU (1) RU2423377C2 (enExample)
TW (1) TWI391403B (enExample)
WO (1) WO2007049803A1 (enExample)
ZA (1) ZA200803525B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2150269B1 (en) * 2007-05-02 2012-11-21 Astellas Pharma Inc. New cyclic peptide compounds
MX2011003259A (es) * 2008-09-24 2011-04-21 Astellas Pharma Inc Compuesto de peptido y metodo para producir el mismo.
RU2492181C2 (ru) * 2009-01-30 2013-09-10 Энанта Фармасьютикалс, Инк. Аналоги циклоспорина для предупреждения или лечения инфекции гепатита с
US8481483B2 (en) 2009-02-19 2013-07-09 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
CN102459160A (zh) * 2009-05-15 2012-05-16 荷兰癌症研究所基金会 赖氨酸化合物和其在肽和蛋白质的位点选择性和化学选择性修饰中的用途
US8367053B2 (en) 2009-07-09 2013-02-05 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8349312B2 (en) 2009-07-09 2013-01-08 Enanta Pharmaceuticals, Inc. Proline substituted cyclosporin analogues
US8685917B2 (en) 2009-07-09 2014-04-01 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
CA2785978A1 (en) * 2009-12-30 2011-07-07 Scynexis, Inc. Cyclosporine analogues
JP2015529206A (ja) 2012-08-25 2015-10-05 ザ・ジョンズ・ホプキンス・ユニバーシティ Ｇａｐｄｈカスケードインヒビター化合物ならびに使用の方法および精神病を含むストレス誘導障害の処置
WO2014049540A2 (en) 2012-09-29 2014-04-03 Novartis Ag Cyclic peptides and use as medicines
US8906853B2 (en) 2012-11-28 2014-12-09 Enanta Pharmaceuticals, Inc. [N-Me-4-hydroxyleucine]-9-cyclosporin analogues for treatment and prevention of hepatitis C infection
HK1223843A1 (zh) * 2013-08-26 2017-08-11 Enanta Pharmaceuticals, Inc. 用於預防或治療丙型肝炎的環孢菌素類似物
US9669095B2 (en) 2014-11-03 2017-06-06 Enanta Pharmaceuticals, Inc. Cyclosporin analogues for preventing or treating hepatitis C infection

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05271267A (ja) * 1991-04-23 1993-10-19 Fujisawa Pharmaceut Co Ltd Ｆｒ９０１４５９物質、その製法及び用途
PT1091975E (pt) 1998-07-01 2006-05-31 Debiopharm Sa Nova ciclosporina com um perfil de actividade melhorado
CA2426381A1 (en) 2000-10-19 2002-04-25 Fujisawa Pharmaceutical Co., Ltd. Cell damage inhibitor
DK1436322T3 (da) * 2001-10-19 2008-11-03 Isotechnika Inc Blandinger af cyclosporinanaloger og deres anvendelse som immunmodulerende midler
GB0320638D0 (en) * 2003-09-03 2003-10-01 Novartis Ag Organic compounds
JP2007015926A (ja) * 2003-10-06 2007-01-25 Fujisawa Pharmaceut Co Ltd Ｃ型肝炎治療剤
PT1802650E (pt) 2004-10-01 2011-12-30 Scynexis Inc Derivados da ciclosporina 3-éter e 3-tioéter substituída para o tratamento e prevenção da infecção de hepatite c
ATE490778T1 (de) 2004-10-01 2010-12-15 Debiopharm Sa Verwendung von äd-mealaü3-äetvalü4-ciclosporin zur behandlung von hepatitis-c-infektion
ES2314731T3 (es) * 2004-11-22 2009-03-16 Astellas Pharma Inc. Analogo de ciclosporina.

Also Published As

Publication number Publication date
EP1957518A1 (en) 2008-08-20
EP1957518B1 (en) 2015-12-09
JP2009513562A (ja) 2009-04-02
RU2423377C2 (ru) 2011-07-10
CA2623898A1 (en) 2007-05-03
PL1957518T3 (pl) 2016-07-29
AU2006306974B2 (en) 2011-09-22
CN101305019B (zh) 2012-12-12
PT1957518E (pt) 2016-02-26
US7872097B2 (en) 2011-01-18
CA2623898C (en) 2013-12-24
TW200732351A (en) 2007-09-01
KR101273681B1 (ko) 2013-06-25
KR20080065297A (ko) 2008-07-11
NO20082354L (no) 2008-07-01
TWI391403B (zh) 2013-04-01
ZA200803525B (en) 2009-08-26
AU2006306974A1 (en) 2007-05-03
RU2008116674A (ru) 2009-10-27
US20090170755A1 (en) 2009-07-02
JP5218051B2 (ja) 2013-06-26
US20100286033A1 (en) 2010-11-11
US8252895B2 (en) 2012-08-28
BRPI0617781A2 (pt) 2011-08-09
WO2007049803A1 (en) 2007-05-03
CN101305019A (zh) 2008-11-12
IL190286A0 (en) 2011-08-01

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