ES2542888T3 - Proaerolisina que contiene secuencias de activación de proteasa y métodos de uso para el tratamiento del cáncer de próstata - Google Patents
Proaerolisina que contiene secuencias de activación de proteasa y métodos de uso para el tratamiento del cáncer de próstata Download PDFInfo
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- ES2542888T3 ES2542888T3 ES10177191.3T ES10177191T ES2542888T3 ES 2542888 T3 ES2542888 T3 ES 2542888T3 ES 10177191 T ES10177191 T ES 10177191T ES 2542888 T3 ES2542888 T3 ES 2542888T3
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- A61K39/001195—Prostate specific membrane antigen [PSMA]
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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Landscapes
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| ES02768702T Expired - Lifetime ES2388170T3 (es) | 2001-08-24 | 2002-08-23 | Proaerolisina que contiene secuencias de activación de proteasa y métodos de uso para el tratamiento del cáncer de próstata |
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| ES02768702T Expired - Lifetime ES2388170T3 (es) | 2001-08-24 | 2002-08-23 | Proaerolisina que contiene secuencias de activación de proteasa y métodos de uso para el tratamiento del cáncer de próstata |
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| WO (1) | WO2003018611A2 (enExample) |
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| WO2004021861A2 (en) * | 2002-09-03 | 2004-03-18 | Vit Lauermann | Targeted release |
| WO2004078097A2 (en) * | 2003-03-03 | 2004-09-16 | University Of Victoria Innovation And Development Corporation | Modified aerolysin linked to a lung cancer binding agent and methods of use for treating lung cancer |
| PL1694845T3 (pl) | 2003-11-28 | 2019-01-31 | National Research Council Of Canada | Przeciwciała przeciwko rakowi i ich zastosowania |
| EP1891093B1 (en) | 2005-06-14 | 2011-03-23 | Protox Therapeutics Incorporated | Method of treating or preventing benign prostatic hyperplasia using modified pore-forming proteins |
| CN100443503C (zh) * | 2005-07-18 | 2008-12-17 | 四川大学华西医院 | 人源化ctla-4单链抗体与人穿孔素通道形成肽p34的重组免疫毒素 |
| US20090016988A1 (en) * | 2005-11-21 | 2009-01-15 | Buckley J Thomas | Modified Pore-Forming Protein Toxins and Use Thereof |
| US8993295B2 (en) | 2006-07-20 | 2015-03-31 | The General Hospital Corporation | Methods, compositions, and kits for the selective activation of protoxins through combinatorial targeting |
| CA2696627C (en) | 2007-08-17 | 2016-09-27 | Purdue Research Foundation | Psma binding ligand-linker conjugates and methods for using |
| WO2010069060A1 (en) * | 2008-12-15 | 2010-06-24 | Protox Therapeutics Inc. | Method for treating prostatitis utilizing modified pore-forming protein proaerolysin |
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- 2002-08-23 DK DK02768702.9T patent/DK1567641T3/da active
- 2002-08-23 EP EP10177191.3A patent/EP2518142B1/en not_active Expired - Lifetime
- 2002-08-23 US US10/487,115 patent/US7282476B2/en not_active Expired - Lifetime
- 2002-08-23 PT PT02768702T patent/PT1567641E/pt unknown
- 2002-08-23 CN CNB028166221A patent/CN100488981C/zh not_active Expired - Fee Related
- 2002-08-23 ES ES10177191.3T patent/ES2542888T3/es not_active Expired - Lifetime
- 2002-08-23 CA CA2457903A patent/CA2457903C/en not_active Expired - Fee Related
- 2002-08-23 ES ES02768702T patent/ES2388170T3/es not_active Expired - Lifetime
- 2002-08-23 WO PCT/US2002/027061 patent/WO2003018611A2/en not_active Ceased
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| US20080089869A1 (en) | 2008-04-17 |
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| CN1636017A (zh) | 2005-07-06 |
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| EP1567641A4 (en) | 2005-12-28 |
| JP4319908B2 (ja) | 2009-08-26 |
| JP2005520490A (ja) | 2005-07-14 |
| US20040235095A1 (en) | 2004-11-25 |
| EP1567641A2 (en) | 2005-08-31 |
| CA2457903C (en) | 2018-04-17 |
| ES2388170T3 (es) | 2012-10-09 |
| CN100488981C (zh) | 2009-05-20 |
| PT1567641E (pt) | 2012-08-21 |
| ZA200402319B (en) | 2005-08-30 |
| EP1567641B1 (en) | 2012-05-23 |
| EP2518142B1 (en) | 2015-07-15 |
| DK1567641T3 (da) | 2012-08-27 |
| AU2002331720B2 (en) | 2007-10-11 |
| EP2518142A1 (en) | 2012-10-31 |
| US20100234300A1 (en) | 2010-09-16 |
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