ES253914A1 - Un metodo para hacer una 2,4-diaminoquinazolina - Google Patents
Un metodo para hacer una 2,4-diaminoquinazolinaInfo
- Publication number
- ES253914A1 ES253914A1 ES0253914A ES253914A ES253914A1 ES 253914 A1 ES253914 A1 ES 253914A1 ES 0253914 A ES0253914 A ES 0253914A ES 253914 A ES253914 A ES 253914A ES 253914 A1 ES253914 A1 ES 253914A1
- Authority
- ES
- Spain
- Prior art keywords
- amino
- quinazolines
- diamino
- methyl
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- XELRMPRLCPFTBH-UHFFFAOYSA-N quinazoline-2,4-diamine Chemical class C1=CC=CC2=NC(N)=NC(N)=C21 XELRMPRLCPFTBH-UHFFFAOYSA-N 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 230000000844 anti-bacterial effect Effects 0.000 abstract 2
- 229940088710 antibiotic agent Drugs 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- JGKIPAMYVUTGMZ-UHFFFAOYSA-N 2-amino-5,6,7,8-tetrahydronaphthalene-1-carbonitrile Chemical compound C1CCCC2=C(C#N)C(N)=CC=C21 JGKIPAMYVUTGMZ-UHFFFAOYSA-N 0.000 abstract 1
- UYTCHVNBUZZWCW-UHFFFAOYSA-N 2-amino-5-butylbenzonitrile Chemical compound CCCCC1=CC=C(N)C(C#N)=C1 UYTCHVNBUZZWCW-UHFFFAOYSA-N 0.000 abstract 1
- DWKGQNHIHZRBJF-UHFFFAOYSA-N 2-amino-5-propylbenzonitrile Chemical compound CCCC1=CC=C(N)C(C#N)=C1 DWKGQNHIHZRBJF-UHFFFAOYSA-N 0.000 abstract 1
- YORYMELVDSCEHF-UHFFFAOYSA-N 2-amino-6-ethylbenzonitrile Chemical compound CCC1=CC=CC(N)=C1C#N YORYMELVDSCEHF-UHFFFAOYSA-N 0.000 abstract 1
- PKOMYWHVCYHAHW-UHFFFAOYSA-N 2-amino-6-methylbenzonitrile Chemical compound CC1=CC=CC(N)=C1C#N PKOMYWHVCYHAHW-UHFFFAOYSA-N 0.000 abstract 1
- HLCPWBZNUKCSBN-UHFFFAOYSA-N 2-aminobenzonitrile Chemical compound NC1=CC=CC=C1C#N HLCPWBZNUKCSBN-UHFFFAOYSA-N 0.000 abstract 1
- VGHBSNNZWPPOKJ-UHFFFAOYSA-N 5-amino-2,3-dihydro-1H-indene-4-carbonitrile Chemical compound C(#N)C1=C2CCCC2=CC=C1N VGHBSNNZWPPOKJ-UHFFFAOYSA-N 0.000 abstract 1
- XDGNFZUIJHZHHP-UHFFFAOYSA-N 5-ethyl-1h-indole-2,3-dione Chemical group CCC1=CC=C2NC(=O)C(=O)C2=C1 XDGNFZUIJHZHHP-UHFFFAOYSA-N 0.000 abstract 1
- KXCXIHCIQLDTKD-UHFFFAOYSA-N N-(4-bromo-2,3-dihydro-1H-inden-5-yl)acetamide Chemical compound BrC1=C2CCCC2=CC=C1NC(C)=O KXCXIHCIQLDTKD-UHFFFAOYSA-N 0.000 abstract 1
- QBORMGBZXFQTDZ-UHFFFAOYSA-N N-(4-cyano-2,3-dihydro-1H-inden-5-yl)acetamide Chemical compound C(C)(=O)NC=1C(=C2CCCC2=CC1)C#N QBORMGBZXFQTDZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000007900 aqueous suspension Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- DOBRDRYODQBAMW-UHFFFAOYSA-N copper(i) cyanide Chemical compound [Cu+].N#[C-] DOBRDRYODQBAMW-UHFFFAOYSA-N 0.000 abstract 1
- 239000006071 cream Substances 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- QGBSISYHAICWAH-UHFFFAOYSA-N dicyandiamide Chemical compound NC(N)=NC#N QGBSISYHAICWAH-UHFFFAOYSA-N 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78022058A | 1958-12-15 | 1958-12-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES253914A1 true ES253914A1 (es) | 1960-05-01 |
Family
ID=25118979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0253914A Expired ES253914A1 (es) | 1958-12-15 | 1959-12-03 | Un metodo para hacer una 2,4-diaminoquinazolina |
Country Status (5)
| Country | Link |
|---|---|
| CH (1) | CH389628A (en, 2012) |
| DE (1) | DE1125939B (en, 2012) |
| ES (1) | ES253914A1 (en, 2012) |
| FR (1) | FR605M (en, 2012) |
| GB (1) | GB935381A (en, 2012) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1045180A (en) * | 1963-09-20 | 1966-10-12 | Parke Davis & Co | Quinazoline derivatives |
| ES2320772T3 (es) | 2003-07-25 | 2009-05-28 | Ciba Holding Inc. | Uso de 2,4-bis (alquilamino)pirimidinas sustituidas o quinazolinas como agentes antimicrobianos. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE737931C (de) * | 1940-07-10 | 1943-07-29 | Ig Farbenindustrie Ag | Verfahren zur Herstellung von 2, 4-Diaminochinazolin |
-
1959
- 1959-11-20 GB GB39469/59A patent/GB935381A/en not_active Expired
- 1959-11-27 CH CH8118059A patent/CH389628A/de unknown
- 1959-12-03 ES ES0253914A patent/ES253914A1/es not_active Expired
- 1959-12-12 DE DEW26879A patent/DE1125939B/de active Pending
-
1960
- 1960-08-31 FR FR837354A patent/FR605M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| GB935381A (en) | 1963-08-28 |
| DE1125939B (de) | 1962-03-22 |
| CH389628A (de) | 1965-03-31 |
| FR605M (en, 2012) | 1961-06-19 |
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