ES2531955T3 - Soluciones estériles de ácido hialurónico - Google Patents

Soluciones estériles de ácido hialurónico Download PDF

Info

Publication number
ES2531955T3
ES2531955T3 ES11702563.5T ES11702563T ES2531955T3 ES 2531955 T3 ES2531955 T3 ES 2531955T3 ES 11702563 T ES11702563 T ES 11702563T ES 2531955 T3 ES2531955 T3 ES 2531955T3
Authority
ES
Spain
Prior art keywords
hyaluronic acid
solution
weight
saline
filtration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11702563.5T
Other languages
English (en)
Spanish (es)
Inventor
Xiaojun Michael Liu
David Joseph Heiler
Thomas Menzel
Abbie BRONGO
Susan E. Burke
Karl Cummins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bausch and Lomb Inc
Original Assignee
Bausch and Lomb Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch and Lomb Inc filed Critical Bausch and Lomb Inc
Application granted granted Critical
Publication of ES2531955T3 publication Critical patent/ES2531955T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/022—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
ES11702563.5T 2010-02-09 2011-01-27 Soluciones estériles de ácido hialurónico Active ES2531955T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US702540 2010-02-09
US12/702,540 US8283463B2 (en) 2010-02-09 2010-02-09 Sterile hyaluronic acid solutions
PCT/US2011/022656 WO2011100114A1 (en) 2010-02-09 2011-01-27 Sterile hyaluronic acid solutions

Publications (1)

Publication Number Publication Date
ES2531955T3 true ES2531955T3 (es) 2015-03-23

Family

ID=43754892

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11702563.5T Active ES2531955T3 (es) 2010-02-09 2011-01-27 Soluciones estériles de ácido hialurónico

Country Status (8)

Country Link
US (2) US8283463B2 (cg-RX-API-DMAC7.html)
EP (2) EP2400993B1 (cg-RX-API-DMAC7.html)
JP (1) JP5789271B2 (cg-RX-API-DMAC7.html)
BR (1) BR112012019008B8 (cg-RX-API-DMAC7.html)
ES (1) ES2531955T3 (cg-RX-API-DMAC7.html)
PL (1) PL2400993T3 (cg-RX-API-DMAC7.html)
TW (1) TWI405595B (cg-RX-API-DMAC7.html)
WO (1) WO2011100114A1 (cg-RX-API-DMAC7.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10189773B2 (en) 2010-05-07 2019-01-29 Medicus Biosciences, Llc In-vivo gelling pharmaceutical pre-formulation
US11083821B2 (en) * 2011-08-10 2021-08-10 C.P. Medical Corporation Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules
US10111985B2 (en) * 2011-08-10 2018-10-30 Medicus Biosciences, Llc Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules
ES2686114T3 (es) * 2011-12-20 2018-10-16 Angioclinic Ag El ácido hialurónico y su uso para el tratamiento de la insuficiencia venosa y las venas varicosas
CA2873105C (en) 2012-05-11 2018-01-16 Medicus Biosciences, Llc Biocompatible hydrogel treatments for retinal detachment
FR3019465B1 (fr) 2014-04-02 2017-06-23 Horus Pharma Composition hyperosmolaire d'acide hyaluronique et son utilisation pour le traitement de l'oedeme corneen
EP3131521B1 (en) 2014-04-17 2020-11-11 Merz Pharma GmbH & Co. KGaA Composition for improving the appearance of ageing skin
US10245324B2 (en) 2014-10-31 2019-04-02 Johnson & Johnson Consumer Inc. Ophthalmic composition
US20170014339A1 (en) * 2015-07-17 2017-01-19 i.com medical GmbH Tear Substitute, Fluid for Being Used as a Tear Substitute, and Method for Producing a Tear Substitute
DE102015226456A1 (de) 2015-12-22 2017-06-22 Heraeus Medical Gmbh Verfahren zur Sterilisation von wässrigen Polysaccharidlösungen und sterile wässrige Polysaccharidlösungen
AR108280A1 (es) 2016-05-05 2018-08-08 Acraf Composición oftálmica que comprende una combinación sinérgica de glucógeno y ácido hialurónico o sal del mismo
HUE058672T2 (hu) * 2016-10-14 2022-09-28 I Com Medical Gmbh Eljárás a szemfelület homeosztázisának megállapítására, helyreállítására és megõrzésére
US12303601B2 (en) * 2017-10-12 2025-05-20 Solyplus Gmbh Methods of fabrication of concentrated and homogeneously wetted massive polymers and applications thereof
CN111196917B (zh) * 2018-11-20 2022-10-14 臧唯 内窥镜用视野清晰剂
KR20220049525A (ko) * 2019-08-21 2022-04-21 가부시키가이샤 시세이도 화장료
IT201900019724A1 (it) 2019-10-24 2021-04-24 Bmg Pharma S P A “procedimento in solvente organico per la purificazione dell’acido ialuronico sale sodico”
IT202000008299A1 (it) * 2020-04-17 2021-10-17 Glycores 2000 Srl Composizione liquida oftalmica comprendente acido ialuronico lineare a basso peso molecolare
KR102549875B1 (ko) * 2020-09-22 2023-07-03 주식회사 필코리아 필러 정제용 장치
CN112255345A (zh) * 2020-10-20 2021-01-22 山东华熙海御生物医药有限公司 一种测定高分子量透明质酸分子量的方法
KR102762718B1 (ko) * 2022-02-23 2025-02-06 주식회사 스카이테라퓨틱스 고분자 히알루론산의 구조체, 이의 제조방법 및 이를 포함하는 화장료 조성물

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141973A (en) 1975-10-17 1979-02-27 Biotrics, Inc. Ultrapure hyaluronic acid and the use thereof
DE2837115A1 (de) 1978-08-25 1980-03-06 Bayer Ag Neues verfahren zur herstellung von sterilen feststoffen
US5093487A (en) 1986-01-06 1992-03-03 Mobay Corporation Low viscosity high molecular weight filter sterilizable hyaluronic acid
RU2067841C1 (ru) * 1994-01-28 1996-10-20 Научно-производственная фирма "Нарт" Способ получения ароматизатора
IT1273011B (it) 1994-07-25 1997-07-01 Trhecnopharma S A Preparato oftalmico per l'uso come lacrima artificiale
US5621093A (en) 1995-06-06 1997-04-15 Anika Research, Inc. Steam-sterilizing solid hyaluronic acid
WO1997033593A1 (en) * 1996-03-15 1997-09-18 Takara Shuzo Co., Ltd. A product of heat treatment of uronic acid, food, drink or drug including the product
KR19980080116A (ko) 1997-03-27 1998-11-25 히라따 다다시 히알루론산 나트륨의 정제법
US6149864A (en) 1998-06-25 2000-11-21 Massachusetts Institute Of Technology Supercritical fluid sterilization method
CH692919A5 (fr) 1999-01-28 2002-12-13 Trb Chemedica S A Procédé de purification de l'acide hyaluronique à poids moléculaire élevé.
KR100354606B1 (ko) 2000-02-01 2002-09-30 주식회사 중외제약 다목적 콘택트 렌즈 관리 용액 조성물
FR2811996B1 (fr) * 2000-07-19 2003-08-08 Corneal Ind Reticulation de polysaccharide(s), preparation d'hydrogel(s) ; polysaccharide(s) et hydrogel(s) obtenus,leurs utilisations
WO2003002159A1 (en) 2001-06-29 2003-01-09 Biovitrum Ab Process for bulk autoclaving
CA2458126C (en) * 2001-11-21 2012-06-26 Novartis Ag Composition for stabilizing hyaluronic acid
DK1526859T3 (da) 2002-08-07 2013-02-04 Medidom Lab Fremgangsmåde til fremstilling af et sterilt præparat af hyaluronsyre med høj molvægt
US6930077B2 (en) 2003-09-10 2005-08-16 Advanced Medical Optics, Inc. Compositions and methods using sub-PPM combinations of polyquaternium-1 and high molecular weight PHMB
US7956180B2 (en) * 2004-05-27 2011-06-07 Novozymes A/S Dried and agglomerated hyaluronic acid product
CN101001649B (zh) 2004-07-09 2011-08-31 弗罗桑医疗设备公司 包括透明质酸的止血组合物及其制备方法
DE102005030011A1 (de) 2005-06-17 2006-12-21 Aesculap Ag & Co. Kg Verfahren zur Herstellung von sterilen Polysaccharidlösungen
US20090036554A1 (en) * 2007-08-01 2009-02-05 Burke Susan E Ophthalmic compositions comprising a terpene compound
JP2011503047A (ja) * 2007-11-13 2011-01-27 バイオ−テクノロジー ゼネラル（イスラエル）リミテッド 粘弾性生体高分子のための希釈濾過滅菌プロセス
CN102209548A (zh) * 2008-09-15 2011-10-05 博士伦公司 包含具有氨基糖单元的聚合物的组合物及其制备和使用方法

Also Published As

Publication number Publication date
BR112012019008A2 (pt) 2015-09-15
EP2400993B1 (en) 2014-12-31
WO2011100114A1 (en) 2011-08-18
US20120295869A1 (en) 2012-11-22
US20110195925A1 (en) 2011-08-11
JP5789271B2 (ja) 2015-10-07
TW201200171A (en) 2012-01-01
TWI405595B (zh) 2013-08-21
PL2400993T3 (pl) 2015-06-30
JP2013518926A (ja) 2013-05-23
US8283463B2 (en) 2012-10-09
BR112012019008B1 (pt) 2018-11-13
EP2865395A1 (en) 2015-04-29
US8530641B2 (en) 2013-09-10
EP2400993A1 (en) 2012-01-04
BR112012019008B8 (pt) 2018-11-27

Similar Documents

Publication Publication Date Title
ES2531955T3 (es) Soluciones estériles de ácido hialurónico
Oprea et al. Recent advances in applications of cellulose derivatives-based composite membranes with hydroxyapatite
Valachová et al. Versatile use of chitosan and hyaluronan in medicine
US4440662A (en) Cleaning composition for contact lenses
ES2622498T3 (es) Composiciones y usos de materiales con actividad antimicrobiana elevada y toxicidad baja
KR20150013161A (ko) 중합체-계열 투석물
Silva et al. Marine-derived polymers in ionic liquids: architectures development and biomedical applications
Kropp et al. Biocompatibility of poly (ester amide)(PEA) microfibrils in ocular tissues
Mehwish et al. Mussel-inspired surface functionalization of porous albumin cryogels supporting synergistic antibacterial/antioxidant activity and bone-like apatite formation
Parcheta et al. Preparation and functionalization of polymers with antibacterial properties—Review of the recent developments
Blažic et al. Cellulose-g-poly (2-(dimethylamino) ethylmethacrylate) hydrogels: synthesis, characterization, antibacterial testing and polymer electrolyte application
Cojocaru et al. Electrospun/3D-printed bicomponent scaffold co-loaded with a prodrug and a drug with antibacterial and immunomodulatory properties
Berton et al. Ionic liquids as tools to incorporate pharmaceutical ingredients into biopolymer-based drug delivery systems
JP2019177042A (ja) 血液浄化器及びその製法
Long et al. Normal-pressure-prepared chitosan carbonate liquid dressing: Spontaneous transformation into a pure chitosan water-resistant film and enhanced wound repair
RU2581827C2 (ru) Композиция в форме жидкости для ухода за контактными линзами и медицинскими материалами
CN106310221B (zh) 一种含有卡非佐米的药物组合物及其制备方法
KR20100092843A (ko) 콘택트렌즈 보존제
KR101169473B1 (ko) 고분자 히알루론산 조성물 제조방법
CN101977938B (zh) 海藻酸盐的超纯化方法
CN115058025B (zh) 无助溶物的含氨基难溶高分子溶液、制备方法及其应用
Sakthi Velu et al. Flufenamic Acid-Loaded Electrospun Nanofibers Based on Chitosan/Poly (vinyl alcohol) Polymeric Composites for Drug Delivery in Biomedical Applications
RU2280041C1 (ru) Способ получения водорастворимых солевых комплексов гиалуроновой кислоты (варианты)
Gulyakin et al. Use of Membrane Filters in Production Technology for Sterile Drugs
Li et al. Non-soluble antibacterial polyurethane based on cation mechanism and functionalized by chitosan and heparin azide