ES2531326T3 - Sistemas de red polimérica para dispositivos médicos y métodos de uso - Google Patents
Sistemas de red polimérica para dispositivos médicos y métodos de uso Download PDFInfo
- Publication number
- ES2531326T3 ES2531326T3 ES04715966T ES04715966T ES2531326T3 ES 2531326 T3 ES2531326 T3 ES 2531326T3 ES 04715966 T ES04715966 T ES 04715966T ES 04715966 T ES04715966 T ES 04715966T ES 2531326 T3 ES2531326 T3 ES 2531326T3
- Authority
- ES
- Spain
- Prior art keywords
- butyl
- methacrylate
- poly
- acrylate
- hydroxyethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- SOGAXMICEFXMKE-UHFFFAOYSA-N Butylmethacrylate Chemical compound CCCCOC(=O)C(C)=C SOGAXMICEFXMKE-UHFFFAOYSA-N 0.000 abstract 3
- GAWIXWVDTYZWAW-UHFFFAOYSA-N C[CH]O Chemical group C[CH]O GAWIXWVDTYZWAW-UHFFFAOYSA-N 0.000 abstract 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 2
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 2
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 229920001577 copolymer Polymers 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 229920001223 polyethylene glycol Polymers 0.000 abstract 2
- 229940124597 therapeutic agent Drugs 0.000 abstract 2
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 abstract 1
- ZHCJKIOPYDCQOC-UHFFFAOYSA-N butyl 2-methylprop-2-enoate;hydrochloride Chemical compound Cl.CCCCOC(=O)C(C)=C ZHCJKIOPYDCQOC-UHFFFAOYSA-N 0.000 abstract 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Substances OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 1
- 229960002897 heparin Drugs 0.000 abstract 1
- 229920000669 heparin Polymers 0.000 abstract 1
- DIDDVZFHORVZMG-UHFFFAOYSA-N methyl 2-methylprop-2-eneperoxoate Chemical compound COOC(=O)C(C)=C DIDDVZFHORVZMG-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/12—Esters of monohydric alcohols or phenols
- C08F220/16—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
- C08F220/18—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
- C08F220/1804—C4-(meth)acrylate, e.g. butyl (meth)acrylate, isobutyl (meth)acrylate or tert-butyl (meth)acrylate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/30—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D133/00—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Coating compositions based on derivatives of such polymers
- C09D133/04—Homopolymers or copolymers of esters
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D133/00—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Coating compositions based on derivatives of such polymers
- C09D133/04—Homopolymers or copolymers of esters
- C09D133/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
- A61L2300/608—Coatings having two or more layers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/02—Methods for coating medical devices
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/12—Esters of monohydric alcohols or phenols
- C08F220/16—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
- C08F220/18—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
- C08F220/1812—C12-(meth)acrylate, e.g. lauryl (meth)acrylate
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
- Y10T428/24942—Structurally defined web or sheet [e.g., overall dimension, etc.] including components having same physical characteristic in differing degree
- Y10T428/2495—Thickness [relative or absolute]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31855—Of addition polymer from unsaturated monomers
- Y10T428/31909—Next to second addition polymer from unsaturated monomers
- Y10T428/31928—Ester, halide or nitrile of addition polymer
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Materials Engineering (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Paints Or Removers (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45133303P | 2003-02-28 | 2003-02-28 | |
| PCT/IB2004/000534 WO2004075943A1 (en) | 2003-02-28 | 2004-03-01 | Polymeric network system for medical devices and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2531326T3 true ES2531326T3 (es) | 2015-03-13 |
Family
ID=32927706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES04715966T Expired - Lifetime ES2531326T3 (es) | 2003-02-28 | 2004-03-01 | Sistemas de red polimérica para dispositivos médicos y métodos de uso |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7655038B2 (enExample) |
| EP (2) | EP1603603B1 (enExample) |
| JP (1) | JP4791349B2 (enExample) |
| AU (1) | AU2004216404C1 (enExample) |
| CA (1) | CA2519503C (enExample) |
| DK (1) | DK1603603T3 (enExample) |
| ES (1) | ES2531326T3 (enExample) |
| HK (1) | HK1215199A1 (enExample) |
| PL (1) | PL1603603T3 (enExample) |
| PT (1) | PT1603603E (enExample) |
| WO (1) | WO2004075943A1 (enExample) |
Families Citing this family (93)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69942348D1 (de) | 1998-04-27 | 2010-06-17 | Surmodics Inc | Bioaktive Wirkstoffe freisetzende Beschichtungen |
| US20020188037A1 (en) * | 1999-04-15 | 2002-12-12 | Chudzik Stephen J. | Method and system for providing bioactive agent release coating |
| US7097850B2 (en) | 2002-06-18 | 2006-08-29 | Surmodics, Inc. | Bioactive agent release coating and controlled humidity method |
| US20040111144A1 (en) * | 2002-12-06 | 2004-06-10 | Lawin Laurie R. | Barriers for polymeric coatings |
| US7758880B2 (en) | 2002-12-11 | 2010-07-20 | Advanced Cardiovascular Systems, Inc. | Biocompatible polyacrylate compositions for medical applications |
| US7776926B1 (en) | 2002-12-11 | 2010-08-17 | Advanced Cardiovascular Systems, Inc. | Biocompatible coating for implantable medical devices |
| AU2004216404C1 (en) | 2003-02-28 | 2011-04-28 | Biointeractions Ltd. | Polymeric network system for medical devices and methods of use |
| WO2005029095A1 (ja) * | 2003-09-19 | 2005-03-31 | Sumitomo Bakelite Co., Ltd. | バイオチップ |
| AU2004281178A1 (en) * | 2003-10-15 | 2005-04-28 | Tyco Healthcare Group, Lp | Method of joining materials |
| US7550444B2 (en) | 2004-03-26 | 2009-06-23 | Surmodics, Inc. | Composition and method for preparing biocompatible surfaces |
| EP1735024A1 (en) | 2004-03-26 | 2006-12-27 | SurModics, Inc. | Process and systems for biocompatible surfaces |
| DE602005015564D1 (de) | 2004-04-06 | 2009-09-03 | Surmodics Inc | Beschichtungszusammensetzungen für bioaktive mittel |
| WO2005115490A2 (en) * | 2004-05-25 | 2005-12-08 | Surmodics, Inc. | Natural biodegradable polysaccharide coatings for meical articles |
| US20060088571A1 (en) * | 2004-10-21 | 2006-04-27 | Medtronic Vascular, Inc. | Biocompatible and hemocompatible polymer compositions |
| US7919110B2 (en) * | 2005-01-25 | 2011-04-05 | Boston Scientific Scimed, Inc. | Medical device drug release regions containing non-covalently bound polymers |
| US8075906B2 (en) * | 2005-02-01 | 2011-12-13 | Boston Scientific Scimed, Inc. | Medical devices having polymeric regions with copolymers containing hydrocarbon and heteroatom-containing monomeric species |
| US20060171980A1 (en) * | 2005-02-01 | 2006-08-03 | Helmus Michael N | Implantable or insertable medical devices having optimal surface energy |
| US7517914B2 (en) * | 2005-04-04 | 2009-04-14 | Boston Scientificscimed, Inc. | Controlled degradation materials for therapeutic agent delivery |
| US7591841B2 (en) * | 2005-12-16 | 2009-09-22 | Advanced Cardiovascular Systems, Inc. | Implantable devices for accelerated healing |
| US20070155907A1 (en) * | 2005-12-30 | 2007-07-05 | Zhao Jonathon Z | Biologically active block copolymers |
| US11039942B2 (en) * | 2006-06-13 | 2021-06-22 | Sino Medical Sciences Technology Inc. | Drug eluting stent and method of use of the same for enabling restoration of functional endothelial cell layers |
| US10188826B2 (en) * | 2006-09-29 | 2019-01-29 | Covidien Lp | Catheters including antimicrobial sleeve and methods of making catheters |
| US9474833B2 (en) * | 2006-12-18 | 2016-10-25 | Cook Medical Technologies Llc | Stent graft with releasable therapeutic agent and soluble coating |
| JP5513370B2 (ja) * | 2007-04-20 | 2014-06-04 | ベクトン・ディキンソン・アンド・カンパニー | ヒドロゲル組成物 |
| US8133553B2 (en) | 2007-06-18 | 2012-03-13 | Zimmer, Inc. | Process for forming a ceramic layer |
| US8309521B2 (en) | 2007-06-19 | 2012-11-13 | Zimmer, Inc. | Spacer with a coating thereon for use with an implant device |
| US8608049B2 (en) | 2007-10-10 | 2013-12-17 | Zimmer, Inc. | Method for bonding a tantalum structure to a cobalt-alloy substrate |
| JP2011509157A (ja) * | 2008-01-09 | 2011-03-24 | イノベイテイブ ヘルス テクノロジーズ エルエルシー | 骨造成および保存のためのインプラントペレットおよび方法 |
| DE102008006654A1 (de) * | 2008-01-30 | 2009-08-06 | Biotronik Vi Patent Ag | Implantat mit einem Grundkörper aus einer biokorrodierbaren Legierung |
| EP2249892B1 (fr) * | 2008-02-21 | 2017-11-15 | Hexacath | Dispositif medical implantable avec une couche de protection/retention d'un agent actif ou medicament, notamment hydrosoluble |
| US8034396B2 (en) * | 2008-04-01 | 2011-10-11 | Tyco Healthcare Group Lp | Bioadhesive composition formed using click chemistry |
| DK2268332T3 (da) * | 2008-04-09 | 2019-05-06 | Aachen Scient International Pte Ltd | Fremgangsmåde til produktion af en bioaktiv overflade på en endoprostese eller på ballonen af et ballonkateter |
| US20090264478A1 (en) * | 2008-04-18 | 2009-10-22 | Warsaw Orthopedic, Inc. | Sulfasalazine formulations in a biodegradable polymer carrier |
| GB0816783D0 (en) * | 2008-09-15 | 2008-10-22 | Carmeda Ab | Immobilised biological entities |
| US8226603B2 (en) | 2008-09-25 | 2012-07-24 | Abbott Cardiovascular Systems Inc. | Expandable member having a covering formed of a fibrous matrix for intraluminal drug delivery |
| US8049061B2 (en) | 2008-09-25 | 2011-11-01 | Abbott Cardiovascular Systems, Inc. | Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery |
| US8076529B2 (en) | 2008-09-26 | 2011-12-13 | Abbott Cardiovascular Systems, Inc. | Expandable member formed of a fibrous matrix for intraluminal drug delivery |
| US8535477B2 (en) | 2009-02-21 | 2013-09-17 | Sofradim Production | Medical devices incorporating functional adhesives |
| WO2010095045A1 (en) | 2009-02-21 | 2010-08-26 | Sofradim Production | Amphiphilic compounds and self-assembling compositions made therefrom |
| EP2398583B1 (en) | 2009-02-21 | 2020-12-23 | Sofradim Production | Apparatus and method of reacting polymers passing through metal ion matrix to produce injectable medical devices |
| US8877170B2 (en) * | 2009-02-21 | 2014-11-04 | Sofradim Production | Medical device with inflammatory response-reducing coating |
| CA2753173C (en) | 2009-02-21 | 2017-05-30 | Sofradim Production | Medical devices with an activated coating |
| US8968818B2 (en) | 2009-02-21 | 2015-03-03 | Covidien Lp | Medical devices having activated surfaces |
| AU2010215196B2 (en) | 2009-02-21 | 2015-04-16 | Covidien Lp | Crosslinked fibers and method of making same by extrusion |
| EP2398523B1 (en) | 2009-02-21 | 2018-04-04 | Covidien LP | Medical devices having activated surfaces |
| US8512728B2 (en) | 2009-02-21 | 2013-08-20 | Sofradim Production | Method of forming a medical device on biological tissue |
| EP2398584A2 (en) | 2009-02-21 | 2011-12-28 | Sofradim Production | Apparatus and method of reaching polymers by exposure to uv radiation to produce injectable medical devices |
| US8663689B2 (en) * | 2009-02-21 | 2014-03-04 | Sofradim Production | Functionalized adhesive medical gel |
| CA2753165A1 (en) | 2009-02-21 | 2010-08-26 | Sofradim Production | Compounds and medical devices activated with solvophobic linkers |
| US8968733B2 (en) * | 2009-02-21 | 2015-03-03 | Sofradim Production | Functionalized surgical adhesives |
| EP2398943B1 (en) | 2009-02-21 | 2013-04-17 | Sofradim Production | Crosslinked fibers and method of making same using uv radiation |
| WO2011072398A1 (en) | 2009-12-18 | 2011-06-23 | Interface Biologics, Inc. | Local delivery of drugs from self assembled coatings |
| EP2338534A2 (de) * | 2009-12-21 | 2011-06-29 | Biotronik VI Patent AG | Medizinisches Implantat, Beschichtungsverfahren sowie Implantationsverfahren |
| GB201004101D0 (en) | 2010-03-12 | 2010-04-28 | Carmeda Ab | Immobilised biological entities |
| WO2011119536A1 (en) | 2010-03-22 | 2011-09-29 | Abbott Cardiovascular Systems Inc. | Stent delivery system having a fibrous matrix covering with improved stent retention |
| WO2011119865A1 (en) * | 2010-03-25 | 2011-09-29 | Tyco Healthcare Group Lp | Chemical knots for sutures |
| EP2550031B1 (en) | 2010-03-25 | 2015-08-19 | Sofradim Production | Medical devices incorporating functional adhesives |
| US9272074B2 (en) | 2010-03-25 | 2016-03-01 | Sofradim Production | Surgical fasteners and methods for sealing wounds |
| SG184244A1 (en) * | 2010-04-03 | 2012-11-29 | Praful Doshi | Medical devices including medicaments and methods of making and using same |
| US10413506B2 (en) | 2010-04-03 | 2019-09-17 | Praful Doshi | Medical devices including medicaments and methods of making and using same including enhancing comfort, enhancing drug penetration, and treatment of myopia |
| CA2804263A1 (en) | 2010-06-29 | 2012-01-12 | Tyco Healthcare Group Lp | Microwave-powered reactor and method for in situ forming implants |
| US8865857B2 (en) | 2010-07-01 | 2014-10-21 | Sofradim Production | Medical device with predefined activated cellular integration |
| AU2011284449B2 (en) | 2010-07-27 | 2015-07-23 | Sofradim Production | Polymeric fibers having tissue reactive members |
| TWI836373B (zh) | 2010-07-30 | 2024-03-21 | 瑞士商愛爾康公司 | 水合隱形鏡片 |
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- 2004-03-01 AU AU2004216404A patent/AU2004216404C1/en not_active Ceased
- 2004-03-01 PL PL04715966T patent/PL1603603T3/pl unknown
- 2004-03-01 WO PCT/IB2004/000534 patent/WO2004075943A1/en not_active Ceased
- 2004-03-01 EP EP20040715966 patent/EP1603603B1/en not_active Expired - Lifetime
- 2004-03-01 EP EP14020085.8A patent/EP2918296A1/en not_active Withdrawn
- 2004-03-01 DK DK04715966.0T patent/DK1603603T3/en active
- 2004-03-01 JP JP2006502480A patent/JP4791349B2/ja not_active Expired - Lifetime
- 2004-03-01 US US10/790,338 patent/US7655038B2/en not_active Ceased
- 2004-03-01 CA CA2519503A patent/CA2519503C/en not_active Expired - Lifetime
- 2004-03-01 ES ES04715966T patent/ES2531326T3/es not_active Expired - Lifetime
- 2004-03-01 PT PT04715966T patent/PT1603603E/pt unknown
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2012
- 2012-02-02 US US13/365,092 patent/USRE45500E1/en active Active
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2016
- 2016-03-16 HK HK16103055.8A patent/HK1215199A1/en unknown
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| CA2519503A1 (en) | 2004-09-10 |
| AU2004216404A1 (en) | 2004-09-10 |
| PT1603603E (pt) | 2015-02-24 |
| EP1603603B1 (en) | 2014-11-19 |
| CA2519503C (en) | 2015-04-28 |
| JP4791349B2 (ja) | 2011-10-12 |
| EP2918296A1 (en) | 2015-09-16 |
| US20040170752A1 (en) | 2004-09-02 |
| AU2004216404C1 (en) | 2011-04-28 |
| EP1603603A1 (en) | 2005-12-14 |
| HK1215199A1 (en) | 2016-08-19 |
| PL1603603T3 (pl) | 2015-07-31 |
| US7655038B2 (en) | 2010-02-02 |
| AU2004216404B2 (en) | 2010-11-25 |
| USRE45500E1 (en) | 2015-04-28 |
| JP2006519049A (ja) | 2006-08-24 |
| WO2004075943A1 (en) | 2004-09-10 |
| DK1603603T3 (en) | 2015-02-23 |
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