ES2453114T3 - Procedimiento para la preparación de sevelámero - Google Patents

Procedimiento para la preparación de sevelámero Download PDF

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Publication number
ES2453114T3
ES2453114T3 ES10727834.3T ES10727834T ES2453114T3 ES 2453114 T3 ES2453114 T3 ES 2453114T3 ES 10727834 T ES10727834 T ES 10727834T ES 2453114 T3 ES2453114 T3 ES 2453114T3
Authority
ES
Spain
Prior art keywords
sevelamer
polyallylamine
process according
epichlorohydrin
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10727834.3T
Other languages
English (en)
Spanish (es)
Inventor
Flavio Villani
Bruno De Angelis
Antonio Nardi
Maria Paternoster
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorio Chimico Internazionale SpA
Original Assignee
Laboratorio Chimico Internazionale SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorio Chimico Internazionale SpA filed Critical Laboratorio Chimico Internazionale SpA
Application granted granted Critical
Publication of ES2453114T3 publication Critical patent/ES2453114T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F26/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F26/02—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/18—Introducing halogen atoms or halogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/44—Preparation of metal salts or ammonium salts
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2339/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Derivatives of such polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Saccharide Compounds (AREA)
ES10727834.3T 2009-05-12 2010-05-10 Procedimiento para la preparación de sevelámero Active ES2453114T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI2009A000816A IT1394299B1 (it) 2009-05-12 2009-05-12 Procedimento per la preparazione di sevelamer
ITMI20090816 2009-05-12
PCT/IB2010/001071 WO2010131092A1 (en) 2009-05-12 2010-05-10 Process for the preparation of sevelamer

Publications (1)

Publication Number Publication Date
ES2453114T3 true ES2453114T3 (es) 2014-04-04

Family

ID=41257151

Family Applications (1)

Application Number Title Priority Date Filing Date
ES10727834.3T Active ES2453114T3 (es) 2009-05-12 2010-05-10 Procedimiento para la preparación de sevelámero

Country Status (13)

Country Link
US (2) US20120101234A1 (enExample)
EP (1) EP2430078B1 (enExample)
JP (1) JP5658744B2 (enExample)
CY (1) CY1114915T1 (enExample)
DK (1) DK2430078T3 (enExample)
EA (1) EA021074B1 (enExample)
ES (1) ES2453114T3 (enExample)
HR (1) HRP20140241T1 (enExample)
IT (1) IT1394299B1 (enExample)
PL (1) PL2430078T3 (enExample)
PT (1) PT2430078E (enExample)
SI (1) SI2430078T1 (enExample)
WO (1) WO2010131092A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101853260B1 (ko) * 2016-11-29 2018-06-14 주식회사 퍼슨 세벨라머 카보네이트의 제조방법
US10479865B2 (en) * 2017-11-01 2019-11-19 Strides Shasun Limited Process for the preparation of sevelamer carbonate
CN115260355A (zh) * 2022-05-16 2022-11-01 江苏中天药业有限公司 一种阴离子交换树脂、其制备方法、该树脂与药物的复合物和其掩味制剂

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3541511A1 (de) * 1985-11-19 1987-05-21 Grace W R Ab Promoter fuer die papierleimung, verfahren zu dessen herstellung und dessen verwendung
US6423754B1 (en) * 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
CA2362410A1 (en) * 1999-04-16 2000-10-26 Abbott Laboratories Process for producing cross-linked polyallylamine hydrochloride
US6362266B1 (en) * 1999-09-03 2002-03-26 The Dow Chemical Company Process for reducing cohesiveness of polyallylamine polymer gels during drying
US6180754B1 (en) * 1999-09-03 2001-01-30 The Dow Chemical Company Process for producing cross-linked polyallylamine polymer
US6600011B2 (en) * 2001-10-09 2003-07-29 Genzyme Corporation Process for purification and drying of polymer hydrogels
US7220406B2 (en) * 2002-10-22 2007-05-22 Genzyme Corporation Method for promoting bone formation
US7459502B2 (en) * 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
JP2005138540A (ja) * 2003-11-10 2005-06-02 Konica Minolta Photo Imaging Inc インクジェット記録材料
JP2009542653A (ja) * 2006-07-05 2009-12-03 ジェンザイム コーポレーション リン酸塩過剰血症のための鉄（ｉｉ）含有治療剤
EP2441779A1 (en) * 2006-09-01 2012-04-18 USV Limited Process for the preparation of sevelamer hydrochloride and formulation thereof

Also Published As

Publication number Publication date
JP5658744B2 (ja) 2015-01-28
JP2012526887A (ja) 2012-11-01
ITMI20090816A1 (it) 2010-11-13
US20120101234A1 (en) 2012-04-26
US9303105B2 (en) 2016-04-05
PL2430078T3 (pl) 2014-06-30
EA021074B1 (ru) 2015-03-31
US20140213736A1 (en) 2014-07-31
DK2430078T3 (en) 2014-03-24
EA201101613A1 (ru) 2012-04-30
EP2430078B1 (en) 2014-01-01
EP2430078A1 (en) 2012-03-21
IT1394299B1 (it) 2012-06-06
SI2430078T1 (sl) 2014-04-30
CY1114915T1 (el) 2016-12-14
HRP20140241T1 (hr) 2014-04-11
PT2430078E (pt) 2014-02-11
WO2010131092A1 (en) 2010-11-18

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