EA201101613A1 - Способ получения севеламера - Google Patents

Способ получения севеламера

Info

Publication number
EA201101613A1
EA201101613A1 EA201101613A EA201101613A EA201101613A1 EA 201101613 A1 EA201101613 A1 EA 201101613A1 EA 201101613 A EA201101613 A EA 201101613A EA 201101613 A EA201101613 A EA 201101613A EA 201101613 A1 EA201101613 A1 EA 201101613A1
Authority
EA
Eurasian Patent Office
Prior art keywords
sevelamer
sevelamera
obtaining
resort
bicarbonate
Prior art date
Application number
EA201101613A
Other languages
English (en)
Other versions
EA021074B1 (ru
Inventor
Флавио Виллани
Бруно Де Анджелис
Антонио Нарди
Мария Патерностер
Original Assignee
Лабораторио Кимико Интернационале С.П.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Лабораторио Кимико Интернационале С.П.А. filed Critical Лабораторио Кимико Интернационале С.П.А.
Publication of EA201101613A1 publication Critical patent/EA201101613A1/ru
Publication of EA021074B1 publication Critical patent/EA021074B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F26/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F26/02—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/18—Introducing halogen atoms or halogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/44—Preparation of metal salts or ammonium salts
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2339/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Derivatives of such polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Настоящее изобретение относится к способу получения севеламера, в частности гидрохлорида севеламера и карбоната/бикарбоната севеламера, при использовании процесса, который делает возможным получение севеламера с хорошими выходами и при использовании обычных реакторов в отсутствие потребности прибегать к использованию специфического и дорогостоящего оборудования.
EA201101613A 2009-05-12 2010-05-10 Способ получения севеламера гидрохлорида и севеламера карбоната/бикарбоната EA021074B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI2009A000816A IT1394299B1 (it) 2009-05-12 2009-05-12 Procedimento per la preparazione di sevelamer
PCT/IB2010/001071 WO2010131092A1 (en) 2009-05-12 2010-05-10 Process for the preparation of sevelamer

Publications (2)

Publication Number Publication Date
EA201101613A1 true EA201101613A1 (ru) 2012-04-30
EA021074B1 EA021074B1 (ru) 2015-03-31

Family

ID=41257151

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201101613A EA021074B1 (ru) 2009-05-12 2010-05-10 Способ получения севеламера гидрохлорида и севеламера карбоната/бикарбоната

Country Status (13)

Country Link
US (2) US20120101234A1 (ru)
EP (1) EP2430078B1 (ru)
JP (1) JP5658744B2 (ru)
CY (1) CY1114915T1 (ru)
DK (1) DK2430078T3 (ru)
EA (1) EA021074B1 (ru)
ES (1) ES2453114T3 (ru)
HR (1) HRP20140241T1 (ru)
IT (1) IT1394299B1 (ru)
PL (1) PL2430078T3 (ru)
PT (1) PT2430078E (ru)
SI (1) SI2430078T1 (ru)
WO (1) WO2010131092A1 (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101853260B1 (ko) * 2016-11-29 2018-06-14 주식회사 퍼슨 세벨라머 카보네이트의 제조방법
US10479865B2 (en) * 2017-11-01 2019-11-19 Strides Shasun Limited Process for the preparation of sevelamer carbonate
CN115260355A (zh) * 2022-05-16 2022-11-01 江苏中天药业有限公司 一种阴离子交换树脂、其制备方法、该树脂与药物的复合物和其掩味制剂

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3541511A1 (de) * 1985-11-19 1987-05-21 Grace W R Ab Promoter fuer die papierleimung, verfahren zu dessen herstellung und dessen verwendung
US6423754B1 (en) * 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
ES2288852T3 (es) * 1999-04-16 2008-02-01 Abbott Laboratories Proceso para producir clorhidrato de polialilamina reticulado.
US6180754B1 (en) * 1999-09-03 2001-01-30 The Dow Chemical Company Process for producing cross-linked polyallylamine polymer
US6362266B1 (en) * 1999-09-03 2002-03-26 The Dow Chemical Company Process for reducing cohesiveness of polyallylamine polymer gels during drying
US6600011B2 (en) * 2001-10-09 2003-07-29 Genzyme Corporation Process for purification and drying of polymer hydrogels
WO2004037274A1 (en) * 2002-10-22 2004-05-06 Genzyme Corporation Amine polymers for promoting bone formation
US7459502B2 (en) * 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
JP2005138540A (ja) * 2003-11-10 2005-06-02 Konica Minolta Photo Imaging Inc インクジェット記録材料
JP2009542653A (ja) * 2006-07-05 2009-12-03 ジェンザイム コーポレーション リン酸塩過剰血症のための鉄（ｉｉ）含有治療剤
KR20090051240A (ko) * 2006-09-01 2009-05-21 유에스브이 리미티드 세벨라머 염산염의 제조방법 및 그의 제형

Also Published As

Publication number Publication date
DK2430078T3 (en) 2014-03-24
ES2453114T3 (es) 2014-04-04
JP5658744B2 (ja) 2015-01-28
EP2430078B1 (en) 2014-01-01
PL2430078T3 (pl) 2014-06-30
US20140213736A1 (en) 2014-07-31
JP2012526887A (ja) 2012-11-01
WO2010131092A1 (en) 2010-11-18
SI2430078T1 (sl) 2014-04-30
PT2430078E (pt) 2014-02-11
US9303105B2 (en) 2016-04-05
EP2430078A1 (en) 2012-03-21
ITMI20090816A1 (it) 2010-11-13
US20120101234A1 (en) 2012-04-26
IT1394299B1 (it) 2012-06-06
EA021074B1 (ru) 2015-03-31
HRP20140241T1 (hr) 2014-04-11
CY1114915T1 (el) 2016-12-14

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU