ES2434215T3 - Biomarcadores relacionados con la diabetes y métodos de uso de los mismos - Google Patents
Biomarcadores relacionados con la diabetes y métodos de uso de los mismos Download PDFInfo
- Publication number
- ES2434215T3 ES2434215T3 ES08746276T ES08746276T ES2434215T3 ES 2434215 T3 ES2434215 T3 ES 2434215T3 ES 08746276 T ES08746276 T ES 08746276T ES 08746276 T ES08746276 T ES 08746276T ES 2434215 T3 ES2434215 T3 ES 2434215T3
- Authority
- ES
- Spain
- Prior art keywords
- measurement data
- diabetes
- methods
- biomarker
- glucose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000000090 biomarker Substances 0.000 title abstract 6
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000005259 measurement Methods 0.000 abstract 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 3
- 102100031786 Adiponectin Human genes 0.000 abstract 2
- 108010074051 C-Reactive Protein Proteins 0.000 abstract 2
- 102100032752 C-reactive protein Human genes 0.000 abstract 2
- 239000008103 glucose Substances 0.000 abstract 2
- 108010076365 Adiponectin Proteins 0.000 abstract 1
- 101000775469 Homo sapiens Adiponectin Proteins 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 238000012502 risk assessment Methods 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/62—Insulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/65—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/788,260 US20070259377A1 (en) | 2005-10-11 | 2007-04-18 | Diabetes-associated markers and methods of use thereof |
| US788260 | 2007-04-18 | ||
| US260907P | 2007-11-08 | 2007-11-08 | |
| US2609 | 2007-11-08 | ||
| PCT/US2008/060830 WO2008131224A2 (en) | 2007-04-18 | 2008-04-18 | Diabetes-related biomarkers and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2434215T3 true ES2434215T3 (es) | 2013-12-16 |
Family
ID=39529374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES08746276T Active ES2434215T3 (es) | 2007-04-18 | 2008-04-18 | Biomarcadores relacionados con la diabetes y métodos de uso de los mismos |
Country Status (10)
| Country | Link |
|---|---|
| EP (3) | EP2891885A3 (enExample) |
| JP (2) | JP5271350B2 (enExample) |
| CN (1) | CN102317786A (enExample) |
| AU (1) | AU2008242764B2 (enExample) |
| BR (1) | BRPI0810409A2 (enExample) |
| CA (1) | CA2684308A1 (enExample) |
| DK (1) | DK2147315T3 (enExample) |
| ES (1) | ES2434215T3 (enExample) |
| TW (1) | TW200849035A (enExample) |
| WO (1) | WO2008131224A2 (enExample) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8119358B2 (en) | 2005-10-11 | 2012-02-21 | Tethys Bioscience, Inc. | Diabetes-related biomarkers and methods of use thereof |
| US9817001B2 (en) | 2008-05-27 | 2017-11-14 | Boston Heart Diagnostics Corporation | Methods for determining LDL cholesterol treatment |
| JP2011528117A (ja) * | 2008-07-15 | 2011-11-10 | メタノミクス ヘルス ゲーエムベーハー | 胃バイパス及びそれに関連する状態を診断する手段及び方法 |
| US8762306B2 (en) | 2008-08-14 | 2014-06-24 | The University Of Toledo | Neural network for glucose therapy recommendation |
| US8470541B1 (en) | 2008-09-27 | 2013-06-25 | Boston Heart Diagnostics Corporation | Methods for separation and immuno-detection of biomolecules, and apparatus related thereto |
| WO2010146182A1 (en) * | 2009-06-19 | 2010-12-23 | Roche Diagnostics Gmbh | Method for monitoring the effect of ace inhibitor therapy on peripheral insulin resistance |
| BR112012004834A2 (pt) * | 2009-09-02 | 2018-03-13 | Univ Virginia Patent Foundation | acompanhar a probabilidade de hipoglicemia iminente em diabetes de dados de automonitiração de glicose no sangue (smbg) |
| US8163704B2 (en) | 2009-10-20 | 2012-04-24 | Novartis Ag | Glycoside derivatives and uses thereof |
| JP2013509588A (ja) * | 2009-10-29 | 2013-03-14 | テシス バイオサイエンス, インコーポレイテッド | 2型糖尿病の予防に対して一貫した改善をもたらすタンパク質バイオマーカーおよび脂質代謝物バイオマーカー |
| US8775095B2 (en) | 2010-06-18 | 2014-07-08 | Roche Diagnostics Operations, Inc. | Methods and apparatus for decentralized diabetes monitoring |
| AU2012322018B2 (en) | 2011-10-13 | 2017-09-21 | Boston Heart Diagnostics | Compositions and methods for treating and preventing coronary heart disease |
| CN103376325A (zh) * | 2012-04-25 | 2013-10-30 | 中国科学院上海生命科学研究院 | 血管紧张素原蛋白前体作为肥胖型糖尿病标志物的应用 |
| WO2014055718A1 (en) * | 2012-10-04 | 2014-04-10 | Aptima, Inc. | Clinical support systems and methods |
| RU2015136673A (ru) * | 2013-01-31 | 2017-03-10 | Каприон Протеомикс Инк. | Биомаркеры сахарного диабета 2 типа и их применение |
| CN103198211B (zh) * | 2013-03-08 | 2017-02-22 | 北京理工大学 | 2型糖尿病发病危险因素对血糖影响的定量分析方法 |
| US9828624B2 (en) | 2013-07-24 | 2017-11-28 | Boston Heart Diagnostics Corporation | Driving patient compliance with therapy |
| CN104714022B (zh) * | 2013-12-12 | 2016-08-17 | 张曼 | 尿液纤维蛋白原α链在2型糖尿病合并冠心病中的应用 |
| AU2014364539B2 (en) * | 2013-12-20 | 2019-08-01 | Metabolon, Inc. | Biomarkers of de novo lipogenesis and methods using the same" (i.e. change Biomakers to Biomarkers) |
| CA2968221A1 (en) | 2014-11-17 | 2016-05-26 | Boston Heart Diagnostic Corporation | Cardiovascular disease risk assessment |
| EP3308291A4 (en) * | 2015-06-15 | 2019-03-20 | Kirontech Holding SAL | METHOD AND DEVICE FOR PROVIDING A PREDICTION |
| US11464456B2 (en) | 2015-08-07 | 2022-10-11 | Aptima, Inc. | Systems and methods to support medical therapy decisions |
| CN108289642B (zh) * | 2015-10-09 | 2021-02-23 | 迪诺威特公司 | 确定胰岛素疗法相关的参数、预测葡萄糖值和提供胰岛素给药建议的医学布置和方法 |
| CN105758984B (zh) * | 2015-12-15 | 2017-07-14 | 中国药科大学 | 衍生化hplc‑dad法测定药物中小分子卤代羧酸的方法 |
| CN106979982B (zh) * | 2016-01-19 | 2021-01-05 | 上海市第六人民医院 | 一种用于糖尿病风险预测、治疗评价的方法及试剂盒 |
| CN105567852A (zh) * | 2016-02-29 | 2016-05-11 | 北京泱深生物信息技术有限公司 | Iqce基因及其表达产物在i型糖尿病诊断中的用途 |
| CN105567851A (zh) * | 2016-02-29 | 2016-05-11 | 北京泱深生物信息技术有限公司 | 一种与糖尿病相关的分子标志物 |
| US10783801B1 (en) | 2016-12-21 | 2020-09-22 | Aptima, Inc. | Simulation based training system for measurement of team cognitive load to automatically customize simulation content |
| US20200124612A1 (en) * | 2017-04-11 | 2020-04-23 | University Of Iowa Research Foundation | Detection of predictors of preeclampsia |
| TWI682330B (zh) * | 2018-05-15 | 2020-01-11 | 美爾敦股份有限公司 | 自學式資料分類系統及方法 |
| CN108760706B (zh) * | 2018-06-08 | 2021-08-06 | 农业部环境保护科研监测所 | 一种快速筛选镉低积累水稻品种的方法 |
| CN109065174B (zh) * | 2018-07-27 | 2022-02-18 | 合肥工业大学 | 考虑相似约束的病历主题获取方法及装置 |
| EP3837286A4 (en) | 2018-08-16 | 2022-08-10 | The Johns Hopkins University | ANTIBODIES TO HUMAN ZNT8 |
| CN109559013A (zh) * | 2018-10-18 | 2019-04-02 | 深圳壹账通智能科技有限公司 | 基于小游戏的风险测试方法及装置、电子设备及可读存储介质 |
| CA3118297A1 (en) * | 2018-10-31 | 2020-05-07 | Better Therapeutics, Inc. | Systems, methods, and apparatuses for managing data for artificial intelligence software and mobile applications in digital health therapeutics |
| CN111378734A (zh) * | 2018-12-28 | 2020-07-07 | 康多富国际有限公司 | 新陈代谢疾病保健食品组合确定方法及其可读存储介质 |
| KR102839365B1 (ko) * | 2019-01-08 | 2025-07-29 | 일루리아 엘티디. | 주의력 결핍 과잉행동 장애 모니터링의 진단 및 효율성 |
| CN110231335A (zh) * | 2019-06-18 | 2019-09-13 | 济南大学 | 一种基于铁蛋白三维结构免疫传感器的制备方法及应用 |
| US12366570B2 (en) | 2019-10-01 | 2025-07-22 | The Johns Hopkins University | Cell-based ZNT8 assay |
| US20210153787A1 (en) * | 2019-11-26 | 2021-05-27 | Dexcom, Inc. | Recommendations based on continuous glucose monitoring |
| CN112881689B (zh) * | 2019-11-29 | 2023-02-10 | 张曼 | 尿液凝血因子ix蛋白及其多肽片段在正常妊娠或妊娠糖尿病中的应用 |
| CN112924682B (zh) * | 2019-12-05 | 2023-02-10 | 张曼 | 尿液纤维蛋白原α链蛋白及其多肽片段在正常妊娠中的应用 |
| CN112924675B (zh) * | 2019-12-05 | 2023-01-13 | 张曼 | 尿液胰腺甘油三酯脂肪酶蛋白及其多肽片段在正常妊娠中的应用 |
| CN111297329B (zh) * | 2020-02-24 | 2023-05-12 | 苏州大学 | 预测糖尿病患者心血管并发症动态发病风险的方法及系统 |
| CN114487431A (zh) * | 2020-11-12 | 2022-05-13 | 首都医科大学附属北京世纪坛医院 | 尿液α-2-HS-糖蛋白及其多肽片段在妊娠糖尿病中的应用 |
| TWI775253B (zh) * | 2020-12-24 | 2022-08-21 | 宏碁股份有限公司 | 高風險用藥路徑的計算方法 |
| CN114048374A (zh) * | 2021-10-28 | 2022-02-15 | 盐城金堤科技有限公司 | 待推荐对象的确定方法以及待推荐对象的确定装置 |
| WO2023084199A1 (en) * | 2021-11-09 | 2023-05-19 | Randox Laboratories Ltd. | Biomarkers of hidden obesity for use in preventative healthcare |
| WO2023102204A1 (en) * | 2021-12-03 | 2023-06-08 | The Trustees Of Indiana University | Biomarker for type 1 diabetes |
| CN115006536A (zh) * | 2022-04-19 | 2022-09-06 | 上海交通大学医学院附属瑞金医院 | Sgk1作为靶点在制备抑制肝糖异生药物中的应用 |
| CN114609395B (zh) * | 2022-04-25 | 2024-03-29 | 李玉凤 | 一种预测或诊断糖尿病或糖尿病肾病患者中的早期动脉粥样硬化的应用 |
| CN116631578B (zh) * | 2023-07-25 | 2023-10-13 | 山东硕杰医疗科技有限公司 | 一种肺癌网络综合管理信息平台 |
| WO2025117310A1 (en) * | 2023-12-01 | 2025-06-05 | Mars, Incorporated | Diabetes prognosis in a feline |
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-
2008
- 2008-04-18 EP EP14188942.8A patent/EP2891885A3/en not_active Withdrawn
- 2008-04-18 JP JP2010504273A patent/JP5271350B2/ja not_active Expired - Fee Related
- 2008-04-18 WO PCT/US2008/060830 patent/WO2008131224A2/en not_active Ceased
- 2008-04-18 ES ES08746276T patent/ES2434215T3/es active Active
- 2008-04-18 AU AU2008242764A patent/AU2008242764B2/en not_active Ceased
- 2008-04-18 CA CA002684308A patent/CA2684308A1/en not_active Abandoned
- 2008-04-18 TW TW097114417A patent/TW200849035A/zh unknown
- 2008-04-18 EP EP08746276.8A patent/EP2147315B1/en active Active
- 2008-04-18 DK DK08746276.8T patent/DK2147315T3/da active
- 2008-04-18 BR BRPI0810409-3A2A patent/BRPI0810409A2/pt not_active IP Right Cessation
- 2008-04-18 EP EP12175286.9A patent/EP2541254B1/en not_active Revoked
- 2008-04-18 CN CN2008800207230A patent/CN102317786A/zh active Pending
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2013
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|---|---|
| AU2008242764B2 (en) | 2013-10-24 |
| AU2008242764A1 (en) | 2008-10-30 |
| EP2147315B1 (en) | 2013-06-26 |
| JP2013079981A (ja) | 2013-05-02 |
| TW200849035A (en) | 2008-12-16 |
| WO2008131224A3 (en) | 2009-01-15 |
| EP2891885A2 (en) | 2015-07-08 |
| EP2891885A3 (en) | 2015-10-14 |
| CA2684308A1 (en) | 2008-10-30 |
| JP5271350B2 (ja) | 2013-08-21 |
| EP2541254A3 (en) | 2013-03-13 |
| EP2541254A2 (en) | 2013-01-02 |
| DK2147315T3 (da) | 2013-09-23 |
| CN102317786A (zh) | 2012-01-11 |
| JP2010525332A (ja) | 2010-07-22 |
| EP2541254B1 (en) | 2014-11-12 |
| BRPI0810409A2 (pt) | 2015-02-18 |
| EP2147315A2 (en) | 2010-01-27 |
| WO2008131224A2 (en) | 2008-10-30 |
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