ES2398394T3 - Reactivos peptídicos específicos de prión - Google Patents

Reactivos peptídicos específicos de prión Download PDF

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Publication number
ES2398394T3
ES2398394T3 ES04781105T ES04781105T ES2398394T3 ES 2398394 T3 ES2398394 T3 ES 2398394T3 ES 04781105 T ES04781105 T ES 04781105T ES 04781105 T ES04781105 T ES 04781105T ES 2398394 T3 ES2398394 T3 ES 2398394T3
Authority
ES
Spain
Prior art keywords
peptide
prion
pathogenic
reagent
peptide reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES04781105T
Other languages
English (en)
Spanish (es)
Inventor
Melissa D. Michelitsch
Celine Hu
Roland N. Zuckermann
Michael D. Connolly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Novartis Vaccines and Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines and Diagnostics Inc filed Critical Novartis Vaccines and Diagnostics Inc
Application granted granted Critical
Publication of ES2398394T3 publication Critical patent/ES2398394T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2828—Prion diseases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
ES04781105T 2003-08-13 2004-08-13 Reactivos peptídicos específicos de prión Expired - Lifetime ES2398394T3 (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US49496203P 2003-08-13 2003-08-13
US494962P 2003-08-13
US57036804P 2004-05-12 2004-05-12
US570368P 2004-05-12
US58650904P 2004-07-09 2004-07-09
US586509P 2004-07-09
PCT/US2004/026363 WO2005016127A2 (en) 2003-08-13 2004-08-13 Prion-specific peptide reagents

Publications (1)

Publication Number Publication Date
ES2398394T3 true ES2398394T3 (es) 2013-03-15

Family

ID=34198970

Family Applications (1)

Application Number Title Priority Date Filing Date
ES04781105T Expired - Lifetime ES2398394T3 (es) 2003-08-13 2004-08-13 Reactivos peptídicos específicos de prión

Country Status (13)

Country Link
US (1) US7439041B2 (OSRAM)
EP (1) EP1653844B1 (OSRAM)
JP (3) JP4709149B2 (OSRAM)
KR (1) KR101166012B1 (OSRAM)
AU (2) AU2004264953B2 (OSRAM)
BR (1) BRPI0413495A (OSRAM)
CA (1) CA2535261C (OSRAM)
DK (1) DK1653844T3 (OSRAM)
ES (1) ES2398394T3 (OSRAM)
IL (1) IL173480A0 (OSRAM)
MX (1) MXPA06001588A (OSRAM)
NZ (2) NZ545385A (OSRAM)
WO (1) WO2005016127A2 (OSRAM)

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US20050026165A1 (en) * 2001-05-31 2005-02-03 Cindy Orser Detection of conformationally altered proteins and prions
MXPA03011000A (es) * 2001-05-31 2004-02-27 Arete Associates Metodo de sensor de proteinas deformadas.
US20060035242A1 (en) * 2004-08-13 2006-02-16 Michelitsch Melissa D Prion-specific peptide reagents
MXPA06001588A (es) * 2003-08-13 2006-08-25 Chiron Corp Reactivos de peptido especificos de prion.
US20060057671A1 (en) * 2004-09-10 2006-03-16 Orser Cindy S Immobilized probes and methods of detecting conformationally altered prion proteins
WO2006076683A2 (en) * 2005-01-13 2006-07-20 Novartis Vaccines And Diagnostics Inc. Isolation and detection of pathogenic prions
JP5162250B2 (ja) * 2005-01-13 2013-03-13 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド プリオン特異的ペプチド試薬を使用するｅｌｉｓａアッセイ
WO2006076497A2 (en) 2005-01-13 2006-07-20 Novartis Vaccines And Diagnostics Inc. Osplation of pathogenic prions
WO2006088823A2 (en) * 2005-02-15 2006-08-24 Adlyfe, Inc. Method for detecting misfolded proteins and prions
NZ563213A (en) * 2005-06-01 2009-07-31 Micromet Ag Anti-IL2 antibodies
US7834144B2 (en) 2005-09-09 2010-11-16 Novartis Ag Prion-specific peptoid reagents
GB0519198D0 (en) * 2005-09-20 2005-10-26 Univ Cambridge Tech Tse detection
CN101802609A (zh) * 2006-07-28 2010-08-11 阿德利夫股份有限公司 用于诊断和治疗的肽探针
CA2684798A1 (en) * 2007-04-04 2008-10-16 Novartis Ag Prion elisa
WO2008124098A1 (en) * 2007-04-04 2008-10-16 Novartis Ag Prion assay
WO2009041902A1 (en) * 2007-09-25 2009-04-02 Loefgren Kajsa Prion protein derived cell penetrating peptides and their uses
US8709472B1 (en) * 2007-11-13 2014-04-29 Abbott Cardiovascular Systems Inc. Bioactive agent-loaded heart-targeting nanoparticles
AU2009243060A1 (en) * 2008-04-30 2009-11-05 Novartis Ag. Assay for pathogenic conformers
EP2128618A1 (en) * 2008-05-30 2009-12-02 Prion Diagnostica S.r.l. A process for monitoring the presence of pathogenic agents in biological fluids by nanostructured materials
US20100129290A1 (en) * 2008-11-26 2010-05-27 I.S.T. Corporation Smart contrast agent and detection method for detecting transition metal ions
US10266585B2 (en) 2009-08-28 2019-04-23 The Board Of Regents Of The Univerity Of Texas System Methods of treating brain injury
CA2817973C (en) * 2010-10-15 2019-06-25 The Board Of Regents Of The University Of Texas System Antibodies that bind amyloid oligomers
CA3001065A1 (en) 2015-10-14 2017-04-20 Xiaoxi WEI Compositions and methods for reducing ice crystal formation
US11231720B2 (en) * 2016-05-10 2022-01-25 Lg Electronics Inc. Moving robot and control method thereof
WO2018005330A1 (en) * 2016-06-27 2018-01-04 Florida State University Research Foundation, Inc. Modified fragments from the octarepeat region of prion protein as hemin binders
WO2018053472A1 (en) * 2016-09-19 2018-03-22 University Of Houston System Compositions and methods of targeting cancer stem cells
JP2021004175A (ja) * 2017-09-04 2021-01-14 国立大学法人東北大学 コンフォメーション病治療用材料、及びその製造方法、並びにコンフォメーション病医薬のスクリーニング方法

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DE69632056T2 (de) * 1995-09-14 2004-12-30 The Regents Of The University Of California, Oakland Für natives prp-sc spezifische antikörper
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Also Published As

Publication number Publication date
JP2007502120A (ja) 2007-02-08
NZ545385A (en) 2010-12-24
WO2005016127A2 (en) 2005-02-24
US7439041B2 (en) 2008-10-21
EP1653844A2 (en) 2006-05-10
KR101166012B1 (ko) 2012-07-23
WO2005016127A3 (en) 2006-12-21
CA2535261A1 (en) 2005-02-24
AU2004264953A1 (en) 2005-02-24
JP2013033060A (ja) 2013-02-14
CA2535261C (en) 2015-11-24
AU2004264953B2 (en) 2009-07-23
JP2010158247A (ja) 2010-07-22
KR20060066088A (ko) 2006-06-15
MXPA06001588A (es) 2006-08-25
IL173480A0 (en) 2006-06-11
DK1653844T3 (da) 2013-03-11
AU2009225337B2 (en) 2012-12-06
EP1653844B1 (en) 2012-12-12
US20050118645A1 (en) 2005-06-02
NZ580256A (en) 2011-07-29
BRPI0413495A (pt) 2006-10-17
HK1090275A1 (en) 2006-12-22
AU2009225337A1 (en) 2009-11-05
JP4709149B2 (ja) 2011-06-22
EP1653844A4 (en) 2009-01-14

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