ES2363795T3 - Compuestos de pirazolo[3,4-b]piridina, y su uso como inhibidores de pde4. - Google Patents
Compuestos de pirazolo[3,4-b]piridina, y su uso como inhibidores de pde4. Download PDFInfo
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- ES2363795T3 ES2363795T3 ES06779578T ES06779578T ES2363795T3 ES 2363795 T3 ES2363795 T3 ES 2363795T3 ES 06779578 T ES06779578 T ES 06779578T ES 06779578 T ES06779578 T ES 06779578T ES 2363795 T3 ES2363795 T3 ES 2363795T3
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- methyl
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| US72159705P | 2005-09-29 | 2005-09-29 | |
| US721597P | 2005-09-29 |
Publications (1)
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| ES2363795T3 true ES2363795T3 (es) | 2011-08-16 |
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| WO (2) | WO2007036734A1 (OSRAM) |
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| DE602006021044D1 (de) * | 2005-09-29 | 2011-05-12 | Glaxo Group Ltd | Pyrazoloä3,4-büpyridinverbindungen und ihre verwendung als pde4-inhibitoren |
| GB0614570D0 (en) * | 2006-07-21 | 2006-08-30 | Glaxo Group Ltd | Compounds |
| JP2009545579A (ja) | 2006-08-01 | 2009-12-24 | グラクソ グループ リミテッド | ピラゾロ［３，４−ｂ］ピリジン化合物、及びｐｄｅ４阻害薬としてのその使用 |
| JP5671236B2 (ja) * | 2007-03-14 | 2015-02-18 | ランバクシー ラボラトリーズ リミテッド | ホスホジエステラーゼ阻害剤としてのピラゾロ（３，４−ｂ）ピリジン誘導体 |
| JP5289308B2 (ja) | 2007-04-26 | 2013-09-11 | 武田薬品工業株式会社 | 二環性化合物およびその医薬用途 |
| EP2249830A4 (en) * | 2008-02-06 | 2012-07-18 | Glaxo Group Ltd | DUAL PHARMACOPHORES, ANTAGONISTS OF MUSCARINIC RECEPTORS AND INHIBITORS OF PDE4 ACTIVITY |
| EP2249646A4 (en) * | 2008-02-06 | 2013-09-25 | Glaxo Group Ltd | PDE4 muscarinic Antagonist-DOPPELPHARMACOPHOREN |
| CA2735956A1 (en) * | 2008-09-19 | 2010-04-29 | Ranbaxy Laboratories Limited | Phosphodiestarase inhibitors |
| WO2010097248A1 (en) | 2009-01-13 | 2010-09-02 | Glaxo Group Limited | Pyrimidinecarboxamide derivatives as inhibitors of syk kinase |
| CN102803227B (zh) * | 2010-03-16 | 2016-01-20 | 默克专利有限公司 | 吗啉基喹唑啉 |
| US8487102B2 (en) * | 2010-04-20 | 2013-07-16 | Hoffmann-La Roche Inc. | Pyrrazolopyridine compounds as dual NK1/NK3 receptor antagonists |
| US20140113898A1 (en) * | 2010-11-08 | 2014-04-24 | Zalicus Pharmaceuticals Ltd. | Bisarylsulfone and dialkylarylsulfone compounds as calcium channel blockers |
| EP2574607A1 (en) * | 2011-09-06 | 2013-04-03 | F. Hoffmann-La Roche AG | PDE10 modulators |
| US9243001B2 (en) | 2013-03-15 | 2016-01-26 | Epizyme, Inc. | Substituted benzene compounds |
| WO2014172044A1 (en) * | 2013-03-15 | 2014-10-23 | Epizyme, Inc. | Substituted benzene compounds |
| US9011934B2 (en) | 2013-06-14 | 2015-04-21 | SatisPharma, LLC | Multi-purpose anti-itch treatment |
| KR102408261B1 (ko) | 2014-02-03 | 2022-06-10 | 비타이 파마슈티컬즈, 엘엘씨 | Ror-감마의 디하이드로피롤로피리딘 저해제 |
| DE102014009164A1 (de) * | 2014-06-03 | 2015-12-03 | Herbalist & Doc Gesundheitsgesellschaft Mbh | Silikonölhaltige nasal anzuwendende Formulierungen |
| UA118989C2 (uk) | 2014-10-14 | 2019-04-10 | Вітае Фармасьютікалс, Інк. | Дигідропіролопіридинові інгібітори ror-гамма |
| US9452178B1 (en) | 2014-10-22 | 2016-09-27 | SatisPharma, LLC | Acne formulations, treatments, and pressure sensitive patches for delivery of acne formulations |
| US9663515B2 (en) | 2014-11-05 | 2017-05-30 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
| US9845308B2 (en) | 2014-11-05 | 2017-12-19 | Vitae Pharmaceuticals, Inc. | Isoindoline inhibitors of ROR-gamma |
| EP3331876B1 (en) | 2015-08-05 | 2020-10-07 | Vitae Pharmaceuticals, LLC | Modulators of ror-gamma |
| KR20180086221A (ko) | 2015-11-20 | 2018-07-30 | 비타이 파마슈티컬즈, 인코포레이티드 | Ror-감마의 조절물질 |
| TWI757266B (zh) | 2016-01-29 | 2022-03-11 | 美商維它藥物有限責任公司 | ＲＯＲ－γ調節劑 |
| US9481674B1 (en) | 2016-06-10 | 2016-11-01 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
| WO2018114657A1 (en) | 2016-12-20 | 2018-06-28 | Syngenta Participations Ag | N-cyclobutyl-thiazol-5-carboxamides with nematicidal activity |
| US11098010B2 (en) | 2017-03-21 | 2021-08-24 | Arbutus Biopharma Corporation | Substituted dihydroindene-4-carboxamides and analogs thereof, and methods using same |
| WO2019018975A1 (en) | 2017-07-24 | 2019-01-31 | Vitae Pharmaceuticals, Inc. | INHIBITORS OF ROR GAMMA |
| IL298639A (en) | 2017-07-24 | 2023-01-01 | Vitae Pharmaceuticals Llc | Inhibitors of gamma ror |
| TW201920188A (zh) * | 2017-08-10 | 2019-06-01 | 美商美國禮來大藥廠 | [1,2,4]三唑衍生物 |
| US20210031012A1 (en) | 2018-01-26 | 2021-02-04 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a pde4 inhibitor |
| WO2020106704A2 (en) | 2018-11-19 | 2020-05-28 | Progenity, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
| CN121197633A (zh) | 2019-12-13 | 2025-12-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| WO2021151014A1 (en) * | 2020-01-23 | 2021-07-29 | Myoforte Therapeutics, Inc. | Pgdh inhibitors and methods of making and using |
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| EP1539753B1 (en) * | 2002-09-16 | 2009-09-09 | Glaxo Group Limited | Pyrazolo(3,4-b)pyridine compounds, and their use as phosphodiesterase inhibitors |
| GB0230045D0 (en) * | 2002-12-23 | 2003-01-29 | Glaxo Group Ltd | Compounds |
| DE602006021044D1 (de) * | 2005-09-29 | 2011-05-12 | Glaxo Group Ltd | Pyrazoloä3,4-büpyridinverbindungen und ihre verwendung als pde4-inhibitoren |
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Also Published As
| Publication number | Publication date |
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| WO2007036733A1 (en) | 2007-04-05 |
| ATE503756T1 (de) | 2011-04-15 |
| EP1940836A1 (en) | 2008-07-09 |
| EP1940835A1 (en) | 2008-07-09 |
| JP5323484B2 (ja) | 2013-10-23 |
| WO2007036734A1 (en) | 2007-04-05 |
| JP2009510044A (ja) | 2009-03-12 |
| JP2009510043A (ja) | 2009-03-12 |
| US20090131431A1 (en) | 2009-05-21 |
| US20080255186A1 (en) | 2008-10-16 |
| DE602006021044D1 (de) | 2011-05-12 |
| EP1940835B1 (en) | 2011-03-30 |
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