ES2316808T3 - Empleo de dihidroimidazolonas para el tratamiento de la epilepsia en perros. - Google Patents

Empleo de dihidroimidazolonas para el tratamiento de la epilepsia en perros. Download PDF

Info

Publication number
ES2316808T3
ES2316808T3 ES03757945T ES03757945T ES2316808T3 ES 2316808 T3 ES2316808 T3 ES 2316808T3 ES 03757945 T ES03757945 T ES 03757945T ES 03757945 T ES03757945 T ES 03757945T ES 2316808 T3 ES2316808 T3 ES 2316808T3
Authority
ES
Spain
Prior art keywords
dogs
attacks
treatment
awd
epilepsy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES03757945T
Other languages
English (en)
Spanish (es)
Inventor
Chris Rundfeldt
Rita Dost
Wolfgang Loscher
Andrea Tipold
Klaus Unverferth
Hans-Joachim Lankau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Vetmedica GmbH
Boehringer Ingelheim Animal Health USA Inc
Original Assignee
Boehringer Ingelheim Vetmedica GmbH
Boehringer Ingelheim Vetmedica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32094042&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2316808(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Vetmedica GmbH, Boehringer Ingelheim Vetmedica Inc filed Critical Boehringer Ingelheim Vetmedica GmbH
Application granted granted Critical
Publication of ES2316808T3 publication Critical patent/ES2316808T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES03757945T 2002-10-10 2003-10-09 Empleo de dihidroimidazolonas para el tratamiento de la epilepsia en perros. Expired - Lifetime ES2316808T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41759002P 2002-10-10 2002-10-10
US417590P 2002-10-10

Publications (1)

Publication Number Publication Date
ES2316808T3 true ES2316808T3 (es) 2009-04-16

Family

ID=32094042

Family Applications (2)

Application Number Title Priority Date Filing Date
ES03757945T Expired - Lifetime ES2316808T3 (es) 2002-10-10 2003-10-09 Empleo de dihidroimidazolonas para el tratamiento de la epilepsia en perros.
ES14191084T Expired - Lifetime ES2908453T3 (es) 2002-10-10 2003-10-09 Uso de dihidroimidazolonas para el tratamiento de perros

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES14191084T Expired - Lifetime ES2908453T3 (es) 2002-10-10 2003-10-09 Uso de dihidroimidazolonas para el tratamiento de perros

Country Status (27)

Country Link
US (5) US20050070537A1 (enExample)
EP (3) EP2036563A1 (enExample)
JP (4) JP4694202B2 (enExample)
KR (2) KR101110587B1 (enExample)
CN (2) CN101890019A (enExample)
AR (1) AR041573A1 (enExample)
AT (1) ATE418337T1 (enExample)
AU (2) AU2003273978B2 (enExample)
BE (1) BE2013C046I2 (enExample)
BR (1) BR0315225A (enExample)
CA (2) CA2501772C (enExample)
CY (3) CY1109961T1 (enExample)
DE (1) DE60325496D1 (enExample)
DK (2) DK2845594T3 (enExample)
ES (2) ES2316808T3 (enExample)
FR (2) FR13C0044I2 (enExample)
HR (3) HRP20200207A2 (enExample)
HU (2) HUS1300035I1 (enExample)
LU (1) LU92238I2 (enExample)
MX (1) MXPA05003663A (enExample)
NZ (1) NZ539864A (enExample)
PL (2) PL238776B1 (enExample)
PT (2) PT2845594T (enExample)
SI (2) SI2845594T1 (enExample)
TW (2) TWI324067B (enExample)
WO (1) WO2004032938A1 (enExample)
ZA (1) ZA200502245B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050070537A1 (en) * 2002-10-10 2005-03-31 Chris Rundfeldt Use of dihydroimidazolones for the treatment of dogs
RU2354377C2 (ru) * 2003-07-11 2009-05-10 Берингер Ингельхайм Ветмедика Гмбх Способ лечения или предупреждения заболеваний центральной нервной системы с использованием соединений, обладающих селективностью в отношении альфа-3-субъединицы бензодиазепинового рецептора
KR20140057604A (ko) 2011-08-12 2014-05-13 베링거잉겔하임베트메디카게엠베하 고양잇과 동물의 심부전을 치료 및 예방하는 방법에 사용하기 위한 퍼니 전류 억제제
JP6193613B2 (ja) * 2013-05-10 2017-09-06 学校法人麻布獣医学園 てんかん発作のモニタリングシステム及びモニタリング方法
US9820988B2 (en) 2014-03-24 2017-11-21 Boehringer Ingelheim Vetmedica Gmbh Treatment of epileptic disorders in feline animals
US9856250B2 (en) 2014-05-28 2018-01-02 Toa Eiyo Ltd. Substituted tropane derivatives
US10117891B2 (en) 2014-09-16 2018-11-06 India Globalization Capital, Inc. Cannabinoid composition for treating pain
US10751300B2 (en) 2015-01-25 2020-08-25 India Globalization Capital, Inc. Composition and method for treating seizure disorders
US10596159B2 (en) 2015-08-12 2020-03-24 India Globalization Capital, Inc. Method and composition for treating cachexia and eating disorders
EP3471746A4 (en) 2016-06-15 2020-02-26 India Globalization Capital, Inc. METHOD AND COMPOSITION FOR TREATING CRAMPING SEASONS

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4044021A (en) 1971-10-21 1977-08-23 American Cyanamid Company Tetrasubstituted imidazolidine diuretics useful in the treatment of hyperaldosteronism
US3932452A (en) 1975-02-07 1976-01-13 Morton-Norwich Products, Inc. 1-Arylmethyl-2-imidazolidinones
US5869481A (en) * 1995-09-05 1999-02-09 Arzneitmittelwerk Dresden G.M.B.H. Anticonvulsive 1-ar(alk)ylimidazolin-2-ones and process for making
DE19532668A1 (de) 1995-09-05 1997-03-06 Dresden Arzneimittel Neue, antikonvulsiv wirkende 1-Ar(alk)yl-imidazolin-2-one, die in 4-Stellung einen disubstituierten Amin-Rest enthalten, und Verfahren zu deren Herstellung
DE19721580A1 (de) * 1997-05-23 1998-11-26 Dresden Arzneimittel Verwendung von 1-Ar(alk)yl-imidazolin-2-one zur Behandlung von Angst- und Spannungszuständen
CA2297723A1 (en) * 1997-06-26 1999-01-07 The Board Of Regents Of The University Of Texas Synthesis of dihydrohonokiol compositions
JP4669095B2 (ja) 1999-07-19 2011-04-13 太陽化学株式会社 ペットの問題行動抑制組成物
EP1485094B2 (de) 2002-03-07 2020-03-25 Boehringer Ingelheim International GmbH Oral zu applizierende darreichungsform für 3- [(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1h-benzimidazol-5-carbonyl)-pyridin-2-yl-amino] -propionsäure-ethylester oder dessen salze
US20050070537A1 (en) * 2002-10-10 2005-03-31 Chris Rundfeldt Use of dihydroimidazolones for the treatment of dogs
DE10339862A1 (de) * 2003-08-29 2005-03-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)- phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester-Methansulfonat und dessen Verwendung als Arzneimittel
KR20140057604A (ko) 2011-08-12 2014-05-13 베링거잉겔하임베트메디카게엠베하 고양잇과 동물의 심부전을 치료 및 예방하는 방법에 사용하기 위한 퍼니 전류 억제제
US9820988B2 (en) 2014-03-24 2017-11-21 Boehringer Ingelheim Vetmedica Gmbh Treatment of epileptic disorders in feline animals

Also Published As

Publication number Publication date
JP4694202B2 (ja) 2011-06-08
FR13C0044I1 (enExample) 2013-08-30
CY1125103T1 (el) 2023-01-05
US8962617B2 (en) 2015-02-24
US20160367562A1 (en) 2016-12-22
US9469611B2 (en) 2016-10-18
SI1553952T1 (sl) 2009-04-30
FR22C1033I1 (fr) 2022-09-09
AR041573A1 (es) 2005-05-18
FR13C0044I2 (fr) 2014-03-07
DE60325496D1 (de) 2009-02-05
CN101890019A (zh) 2010-11-24
CA2501772A1 (en) 2004-04-22
EP2036563A1 (en) 2009-03-18
HK1085920A1 (zh) 2006-09-08
PL214702B1 (pl) 2013-09-30
NZ539864A (en) 2007-11-30
PL238776B1 (pl) 2021-10-04
EP1553952A1 (en) 2005-07-20
WO2004032938A1 (en) 2004-04-22
US20080027057A1 (en) 2008-01-31
AU2003273978A1 (en) 2004-05-04
MXPA05003663A (es) 2005-06-08
PL397320A1 (pl) 2012-02-13
HUS1300035I1 (hu) 2017-10-30
CY1109961T1 (el) 2014-09-10
JP2014080449A (ja) 2014-05-08
KR20050056237A (ko) 2005-06-14
US20050070537A1 (en) 2005-03-31
HRP20090667A2 (hr) 2010-07-31
JP6249812B2 (ja) 2017-12-20
CN1726040B (zh) 2010-05-12
JP2006503873A (ja) 2006-02-02
US8859540B2 (en) 2014-10-14
BE2013C046I2 (enExample) 2022-08-09
US20150072983A1 (en) 2015-03-12
HRP20050322B1 (hr) 2013-12-06
CN1726040A (zh) 2006-01-25
LU92238I2 (fr) 2013-09-03
ES2908453T3 (es) 2022-04-29
HRP20090667B1 (hr) 2021-06-11
KR20110063843A (ko) 2011-06-14
US20130065898A1 (en) 2013-03-14
PT2845594T (pt) 2022-03-09
TWI424849B (zh) 2014-02-01
AU2003273978B2 (en) 2009-07-23
CY2013031I2 (el) 2015-11-04
HRP20050322A2 (en) 2006-05-31
CY2013031I1 (el) 2015-11-04
KR101110587B1 (ko) 2012-02-15
TW200503726A (en) 2005-02-01
CA2727722A1 (en) 2004-04-22
ZA200502245B (en) 2005-11-30
TW201010706A (en) 2010-03-16
EP1553952B1 (en) 2008-12-24
HUS2200036I1 (hu) 2022-08-28
SI2845594T1 (sl) 2022-04-29
BR0315225A (pt) 2005-08-23
AU2009225322A1 (en) 2009-11-05
TWI324067B (en) 2010-05-01
CA2501772C (en) 2011-08-23
JP2016104817A (ja) 2016-06-09
JP2011068685A (ja) 2011-04-07
DK2845594T3 (da) 2022-03-07
CA2727722C (en) 2013-05-28
HRP20200207A2 (hr) 2020-07-24
EP2845594A1 (en) 2015-03-11
ATE418337T1 (de) 2009-01-15
PL374603A1 (en) 2005-10-31
DK1553952T3 (da) 2009-04-20
LU92238I9 (enExample) 2019-01-09
PT1553952E (pt) 2009-02-10
EP2845594B1 (en) 2022-02-23

Similar Documents

Publication Publication Date Title
Podell Seizures
US9469611B2 (en) Use of dihydroimidazolones for the treatment of dogs
ES2980828T3 (es) Pautas posológicas para el tratamiento de enfermedad de Pompe
ES3004516T3 (en) Methods of treating sjögren's syndrome using a bruton's tyrosine kinase inhibitor
ES2912306T3 (es) Tetratiomolibdato de bis-colina para el tratamiento de enfermedad de Wilson
US20180271840A1 (en) Compositions and methods for treating amyotrophic lateral sclerosis in responders
WO2014134569A1 (en) Compositions and methods for treating amyotrophic lateral sclerosis in responders
ES2244968T3 (es) Reduccion del volumen de infarto usando citocolina.
Sanders Cerebellar diseases and tremor syndromes
US20260076986A1 (en) A combination of scyllo-inositol and flavones
US11617763B2 (en) Treatment of bone marrow pathologies with polysufated polysaccharides
BR112015032534B1 (pt) Uso de compostos ou sal ou solvato farmaceuticamente aceitável dos mesmos
EP2982382A1 (en) Compounds for preventing ototoxicity
WO2020243612A1 (en) Method of preventing and treating thrombosis
Schwarz et al. Seizures in an Arabian foal due to suspected prolonged transient neonatal hypoparathyroidism
Linfield et al. Impact of Apitegromab on Motor Function in Spinal Muscular Atrophy
AU2012258470B2 (en) Use of dihydroimidazolones for the treatment of epilepsy in dogs
EP2961404B1 (en) Compositions and methods for treating amyotrophic lateral sclerosis in responders
WO2025264695A1 (en) Compositions and methods for treatment
Sørensen et al. Phase II study of gemcitabine and vindesine in patients with previously untreated non-resectable non-small-cell lung cancer
CN114828962A (zh) 用于治疗cns淋巴瘤的谷卡匹酶与甲氨蝶呤/利妥昔单抗的联合疗法
NZ554935A (en) Use of dihydroimidazolones for the treatment of behavioural abnormalities in dogs
HK40083824A (en) Methods of treating lennox-gastaut syndrome using fenfluramine
Nowicki et al. Ukrain treatment of astrocytomas in girl with tuberous sclerosis: a case report
HK40083190A (en) Methods of treating lennox-gastaut syndrome using fenfluramine