ES2295685T3 - Derivados de pirimidina como moduladores de la actividad del receptor de quimioquinas. - Google Patents

Derivados de pirimidina como moduladores de la actividad del receptor de quimioquinas. Download PDF

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Publication number
ES2295685T3
ES2295685T3 ES03792486T ES03792486T ES2295685T3 ES 2295685 T3 ES2295685 T3 ES 2295685T3 ES 03792486 T ES03792486 T ES 03792486T ES 03792486 T ES03792486 T ES 03792486T ES 2295685 T3 ES2295685 T3 ES 2295685T3
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Prior art keywords
hydroxy
amino
thio
methylethyl
alkyl
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Expired - Lifetime
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ES03792486T
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English (en)
Spanish (es)
Inventor
Mark Richard AstraZeneca R & D Charnwood EBDEN
Premji AstraZeneca R & D Charnwood MEGHANI
Antony Ronald AstraZeneca R & D Charnwood COOK
John AstraZeneca R & D Charnwood STEELE
Lal L. S. AstraZeneca R & D Charnwood CHEEMA
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AstraZeneca AB
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AstraZeneca AB
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Priority claimed from GB0219819A external-priority patent/GB0219819D0/en
Priority claimed from GB0223287A external-priority patent/GB0223287D0/en
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Publication of ES2295685T3 publication Critical patent/ES2295685T3/es
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    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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  • Bioinformatics & Cheminformatics (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
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  • Hematology (AREA)
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  • Urology & Nephrology (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Transplantation (AREA)
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ES03792486T 2002-08-24 2003-08-20 Derivados de pirimidina como moduladores de la actividad del receptor de quimioquinas. Expired - Lifetime ES2295685T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0219819 2002-08-24
GB0219819A GB0219819D0 (en) 2002-08-24 2002-08-24 Novel compound
GB0223287A GB0223287D0 (en) 2002-10-08 2002-10-08 Novel compound
GB0223287 2002-10-08

Publications (1)

Publication Number Publication Date
ES2295685T3 true ES2295685T3 (es) 2008-04-16

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ES03792486T Expired - Lifetime ES2295685T3 (es) 2002-08-24 2003-08-20 Derivados de pirimidina como moduladores de la actividad del receptor de quimioquinas.

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US (1) US7482355B2 (enExample)
EP (1) EP1539713B1 (enExample)
JP (2) JP4694963B2 (enExample)
AT (1) ATE381546T1 (enExample)
AU (1) AU2003255819A1 (enExample)
DE (1) DE60318219T2 (enExample)
ES (1) ES2295685T3 (enExample)
WO (1) WO2004018435A1 (enExample)

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US7037916B2 (en) 1999-07-15 2006-05-02 Pharmacopeia Drug Discovery, Inc. Pyrimidine derivatives as IL-8 receptor antagonists
GB0217431D0 (en) 2002-07-27 2002-09-04 Astrazeneca Ab Novel compounds
US8529625B2 (en) 2003-08-22 2013-09-10 Smith & Nephew, Inc. Tissue repair and replacement
EP2311827A1 (en) * 2004-08-28 2011-04-20 AstraZeneca AB Thiopyrimidine derivative, useful as an intermediate for chemokine receptor modulators.
CN101084214A (zh) 2004-11-17 2007-12-05 迈卡纳治疗股份有限公司 激酶抑制剂
KR101487027B1 (ko) * 2005-09-30 2015-01-28 미카나 테라퓨틱스, 인크. 치환된 피라졸 화합물
KR20090086080A (ko) * 2006-11-23 2009-08-10 노파르티스 아게 피리미딘 및 그의 ｃｘｃｒ2 수용체 길항제로서의 용도
EP2166849A4 (en) * 2007-06-11 2010-09-15 Miikana Therapeutics Inc SUBSTITUTED PYRAZOL COMPOUNDS
US9273077B2 (en) 2008-05-21 2016-03-01 Ariad Pharmaceuticals, Inc. Phosphorus derivatives as kinase inhibitors
MX353308B (es) 2008-05-21 2018-01-08 Ariad Pharma Inc Derivados fosforosos como inhibidores de cinasa.
WO2009151910A2 (en) * 2008-05-25 2009-12-17 Wyeth Combination product of receptor tyrosine kinase inhibitor and fatty acid synthase inhibitor for treating cancer
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