ES2287517T3 - Metodo y aparato para la administracion epidermica de una sustancia. - Google Patents
Metodo y aparato para la administracion epidermica de una sustancia. Download PDFInfo
- Publication number
- ES2287517T3 ES2287517T3 ES03755805T ES03755805T ES2287517T3 ES 2287517 T3 ES2287517 T3 ES 2287517T3 ES 03755805 T ES03755805 T ES 03755805T ES 03755805 T ES03755805 T ES 03755805T ES 2287517 T3 ES2287517 T3 ES 2287517T3
- Authority
- ES
- Spain
- Prior art keywords
- needle
- skin
- substance
- port
- discharge
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000126 substance Substances 0.000 title claims abstract description 66
- 238000000034 method Methods 0.000 title abstract description 8
- 230000037368 penetrate the skin Effects 0.000 claims abstract description 8
- 239000003814 drug Substances 0.000 claims description 35
- 229940079593 drug Drugs 0.000 claims description 26
- 230000035515 penetration Effects 0.000 claims description 24
- 238000001802 infusion Methods 0.000 claims description 17
- 239000007788 liquid Substances 0.000 claims description 9
- 230000004308 accommodation Effects 0.000 claims description 2
- 230000002051 biphasic effect Effects 0.000 claims description 2
- 210000003491 skin Anatomy 0.000 description 69
- 210000002615 epidermis Anatomy 0.000 description 25
- 210000004207 dermis Anatomy 0.000 description 24
- 239000012530 fluid Substances 0.000 description 23
- 238000002347 injection Methods 0.000 description 17
- 239000007924 injection Substances 0.000 description 17
- 238000007920 subcutaneous administration Methods 0.000 description 13
- 229960005486 vaccine Drugs 0.000 description 11
- 238000012360 testing method Methods 0.000 description 9
- 210000001519 tissue Anatomy 0.000 description 9
- 238000002483 medication Methods 0.000 description 8
- 238000010521 absorption reaction Methods 0.000 description 7
- 206010033675 panniculitis Diseases 0.000 description 7
- 210000004304 subcutaneous tissue Anatomy 0.000 description 7
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 239000000427 antigen Substances 0.000 description 4
- 102000036639 antigens Human genes 0.000 description 4
- 108091007433 antigens Proteins 0.000 description 4
- 238000013459 approach Methods 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 238000003780 insertion Methods 0.000 description 4
- 230000037431 insertion Effects 0.000 description 4
- 238000007918 intramuscular administration Methods 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 102000004877 Insulin Human genes 0.000 description 3
- 108090001061 Insulin Proteins 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 229940125396 insulin Drugs 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 210000000434 stratum corneum Anatomy 0.000 description 3
- 238000010254 subcutaneous injection Methods 0.000 description 3
- 239000007929 subcutaneous injection Substances 0.000 description 3
- 238000002255 vaccination Methods 0.000 description 3
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 210000002808 connective tissue Anatomy 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 229920002521 macromolecule Polymers 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 239000004005 microsphere Substances 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 230000035479 physiological effects, processes and functions Effects 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 102000055006 Calcitonin Human genes 0.000 description 1
- 108060001064 Calcitonin Proteins 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 244000273618 Sphenoclea zeylanica Species 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 210000000577 adipose tissue Anatomy 0.000 description 1
- 239000003708 ampul Substances 0.000 description 1
- 230000003466 anti-cipated effect Effects 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 description 1
- 229960004015 calcitonin Drugs 0.000 description 1
- 229960000484 ceftazidime Drugs 0.000 description 1
- NMVPEQXCMGEDNH-TZVUEUGBSA-N ceftazidime pentahydrate Chemical compound O.O.O.O.O.S([C@@H]1[C@@H](C(N1C=1C([O-])=O)=O)NC(=O)\C(=N/OC(C)(C)C(O)=O)C=2N=C(N)SC=2)CC=1C[N+]1=CC=CC=C1 NMVPEQXCMGEDNH-TZVUEUGBSA-N 0.000 description 1
- 229960002940 ceftazidime sodium Drugs 0.000 description 1
- JEEWDSDYUSEQML-ROMZVAKDSA-M ceftazidime sodium Chemical compound [Na+].S([C@@H]1[C@@H](C(N1C=1C([O-])=O)=O)NC(=O)\C(=N/OC(C)(C)C([O-])=O)C=2N=C(N)SC=2)CC=1C[N+]1=CC=CC=C1 JEEWDSDYUSEQML-ROMZVAKDSA-M 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 238000005056 compaction Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000013583 drug formulation Substances 0.000 description 1
- 238000004520 electroporation Methods 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000003978 infusion fluid Substances 0.000 description 1
- 239000007927 intramuscular injection Substances 0.000 description 1
- 238000010255 intramuscular injection Methods 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 150000002605 large molecules Chemical class 0.000 description 1
- 230000001926 lymphatic effect Effects 0.000 description 1
- 210000001365 lymphatic vessel Anatomy 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000036470 plasma concentration Effects 0.000 description 1
- -1 proteins Chemical class 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000008591 skin barrier function Effects 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000007910 systemic administration Methods 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229960001005 tuberculin Drugs 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
- A61M5/3291—Shafts with additional lateral openings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/148—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M2005/14208—Pressure infusion, e.g. using pumps with a programmable infusion control system, characterised by the infusion program
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
- A61M2005/1581—Right-angle needle-type devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Surgical Instruments (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40919302P | 2002-09-10 | 2002-09-10 | |
| US409193P | 2002-09-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2287517T3 true ES2287517T3 (es) | 2007-12-16 |
Family
ID=31993949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES03755805T Expired - Lifetime ES2287517T3 (es) | 2002-09-10 | 2003-09-10 | Metodo y aparato para la administracion epidermica de una sustancia. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20040092893A1 (https=) |
| EP (1) | EP1539281B1 (https=) |
| JP (1) | JP2005537893A (https=) |
| AT (1) | ATE363310T1 (https=) |
| AU (1) | AU2003273306B2 (https=) |
| CA (1) | CA2498027C (https=) |
| DE (1) | DE60314157T2 (https=) |
| DK (1) | DK1539281T3 (https=) |
| ES (1) | ES2287517T3 (https=) |
| WO (1) | WO2004024219A1 (https=) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002005866A2 (en) * | 2000-07-13 | 2002-01-24 | Bioheart, Inc. | Deployment system for myocardial cellular material |
| US8574195B2 (en) * | 2002-06-10 | 2013-11-05 | Advanced Cardiovascular Systems, Inc. | Systems and methods for detecting tissue contact and needle penetration depth using static fluid pressure measurements |
| US7364567B2 (en) * | 2002-06-10 | 2008-04-29 | Abbott Cardiovascular Systems Inc. | Systems and methods for detecting tissue contact and needle penetration depth |
| EP1617888B1 (en) | 2003-04-23 | 2019-06-12 | Valeritas, Inc. | Hydraulically actuated pump for long duration medicament administration |
| US8308708B2 (en) * | 2003-07-15 | 2012-11-13 | Abbott Cardiovascular Systems Inc. | Deployment system for myocardial cellular material |
| US7787923B2 (en) * | 2003-11-26 | 2010-08-31 | Becton, Dickinson And Company | Fiber optic device for sensing analytes and method of making same |
| WO2006014425A1 (en) | 2004-07-02 | 2006-02-09 | Biovalve Technologies, Inc. | Methods and devices for delivering glp-1 and uses thereof |
| EP1762259B2 (en) | 2005-09-12 | 2025-01-01 | Unomedical A/S | Inserter for an infusion set with a first and second spring units |
| CA2642415A1 (en) | 2006-02-28 | 2007-09-07 | Unomedical A/S | Inserter for infusion part and infusion part provided with needle protector |
| CN103239773B (zh) | 2006-03-30 | 2015-08-26 | 瓦莱里塔斯公司 | 多筒式流体递送器械 |
| WO2007140785A1 (en) | 2006-06-09 | 2007-12-13 | Unomedical A/S | Mounting pad |
| CA2658577A1 (en) | 2006-08-02 | 2008-02-07 | Unomedical A/S | Cannula and delivery device |
| JP2010502267A (ja) * | 2006-08-28 | 2010-01-28 | エージェンシー・フォー・サイエンス・テクノロジー・アンド・リサーチ | マイクロニードルおよびマイクロニードルの製造方法 |
| JP2010503454A (ja) * | 2006-09-18 | 2010-02-04 | エージェンシー フォー サイエンス、テクノロジー アンド リサーチ | 針構造および針構造を製作するための方法 |
| PL2252349T3 (pl) | 2008-02-13 | 2012-01-31 | Unomedical As | Uszczelnienie między częścią kaniulową a drogą przepływu płynu |
| CA2715667A1 (en) | 2008-02-20 | 2009-08-27 | Unomedical A/S | Insertion device with horizontally moving part |
| CN102256657A (zh) | 2008-12-22 | 2011-11-23 | 犹诺医药有限公司 | 包括粘合垫的医疗器械 |
| CA3149758C (en) * | 2009-01-12 | 2026-01-13 | Becton, Dickinson And Company | Infusion set and/or patch pump having at least one of an in-dwelling rigid catheter with flexible features and/or a flexible catheter attachment |
| US20120265166A1 (en) * | 2009-03-30 | 2012-10-18 | Ofer Yodfat | Devices and methods for enhancing drug absorption rate |
| AU2010277755A1 (en) | 2009-07-30 | 2012-02-02 | Unomedical A/S | Inserter device with horizontal moving part |
| MX2012000778A (es) | 2009-08-07 | 2012-07-30 | Unomedical As | Dispositivo de suministro con sensor y una o mas canulas. |
| US9199034B2 (en) * | 2009-11-09 | 2015-12-01 | Becton, Dickinson And Company | Drug delivery devices, systems, and methods |
| US8449504B2 (en) * | 2009-11-11 | 2013-05-28 | Calibra Medical, Inc. | Wearable infusion device and system |
| MX2012011085A (es) | 2010-03-30 | 2012-10-10 | Unomedical As | Dispositivo medico. |
| EP2433663A1 (en) | 2010-09-27 | 2012-03-28 | Unomedical A/S | Insertion system |
| EP2436412A1 (en) * | 2010-10-04 | 2012-04-04 | Unomedical A/S | A sprinkler cannula |
| US20120209245A1 (en) * | 2011-02-16 | 2012-08-16 | Greg Yukio Uramoto | Process for using a needle having multiple apertures for injections into subcutaneous tissue |
| WO2013050277A1 (en) | 2011-10-05 | 2013-04-11 | Unomedical A/S | Inserter for simultaneous insertion of multiple transcutaneous parts |
| EP2583715A1 (en) | 2011-10-19 | 2013-04-24 | Unomedical A/S | Infusion tube system and method for manufacture |
| US9440051B2 (en) | 2011-10-27 | 2016-09-13 | Unomedical A/S | Inserter for a multiplicity of subcutaneous parts |
| JP5767568B2 (ja) * | 2011-11-16 | 2015-08-19 | ニプロ株式会社 | ワクチン接種針 |
| CA3012939C (en) | 2011-12-07 | 2020-07-21 | Becton, Dickinson And Company | Needle shielding assemblies and infusion devices for use therewith |
| CA3043590C (en) | 2011-12-07 | 2021-10-19 | Becton, Dickinson And Company | Infusion device with releasable fluid connector |
| CA3077820C (en) * | 2012-01-05 | 2023-03-07 | Becton, Dickinson And Company | Split and side-ported catheter devices |
| US10201655B2 (en) * | 2012-08-13 | 2019-02-12 | The Brigham And Women's Hospital, Inc. | Methods and devices for inserting a needle |
| EP3656426B1 (en) * | 2012-11-21 | 2023-05-17 | Amgen Inc. | Drug delivery device |
| CA2915118C (en) | 2013-06-10 | 2021-08-31 | Facet Technologies, Llc | Lancet needle with alignment and retention notch |
| JPWO2015107774A1 (ja) * | 2014-01-16 | 2017-03-23 | テルモ株式会社 | 皮膚上層部への薬液注入用注射器 |
| WO2016178914A1 (en) * | 2015-05-01 | 2016-11-10 | Cesca Therapeutics, Inc. | Intramuscular adaminstration of autologous bone marrw for treatment |
| EP3323453A4 (en) | 2015-07-15 | 2019-01-09 | Terumo Kabushiki Kaisha | INTRADERMAL INJECTION NEEDLE FOR IMMUNOTHERAPY |
| CN109069740B (zh) | 2016-04-22 | 2021-10-29 | 伊莱利利公司 | 用于减少胰岛素中的间甲酚浓度的具有包含聚合吸着剂的组件的输注组 |
| WO2019058361A1 (en) * | 2017-09-24 | 2019-03-28 | Perfaction Technologies Ltd. | NEEDLE DEVICE FOR SUB-CUTANEOUS SELECTIVE LIQUID INJECTION |
| US11712549B2 (en) | 2018-06-28 | 2023-08-01 | Kinneret Rand | Anti-clogging and anti-adhesive micro-capillary needle with enhanced tip visibility |
| US12296109B2 (en) * | 2018-12-07 | 2025-05-13 | Becton, Dickinson And Company | Injection molded cannula and method for making same |
| EP4643903A3 (en) | 2019-02-22 | 2026-01-14 | DEKA Products Limited Partnership | Inserter assembly for infusion sets |
| US12539361B2 (en) | 2019-02-22 | 2026-02-03 | Deka Products Limited Partnership | Infusion set and inserter assembly apparatuses, systems, and methods |
| AU2020454840A1 (en) * | 2020-06-25 | 2023-02-09 | Bard Peripheral Vascular, Inc. | Medical delivery assembly with multi-port needle |
| US20240390581A1 (en) * | 2021-07-07 | 2024-11-28 | Psoulmed, Llc | Method and apparatus for a steady state intramuscular infusion of serotonergic drugs |
| USD1013864S1 (en) | 2021-08-26 | 2024-02-06 | Deka Products Limited Partnership | Fluid administration apparatus assembly |
| CN115154876A (zh) * | 2022-05-24 | 2022-10-11 | 北京化工大学 | 一种麦穗形状的仿生多孔微针经皮给药系统 |
| USD1043976S1 (en) | 2022-08-26 | 2024-09-24 | Deka Products Limited Partnership | Fluid transfer connector |
| USD1057941S1 (en) | 2022-08-26 | 2025-01-14 | Deka Products Limited Partnership | Patient care assembly component |
| USD1090862S1 (en) | 2022-08-26 | 2025-08-26 | Deka Products Limited Partnership | Adhering assembly for medical devices and the like |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE446818C (de) * | 1923-07-19 | 1927-07-11 | Hermann Weyl Dr | Nadelfoermige Kanuele |
| US1740174A (en) * | 1928-09-10 | 1929-12-17 | Hevern Earl Ramsey | Embalmer's trocar |
| US2653607A (en) * | 1950-09-16 | 1953-09-29 | Ayerst Mckenna & Harrison | Injection apparatus |
| US2748769A (en) * | 1953-02-24 | 1956-06-05 | Huber Jennie | Hypodermic needle |
| US3076457A (en) * | 1961-02-14 | 1963-02-05 | Copen Simon Irving | Hypodermic needle |
| US4411657A (en) * | 1980-05-19 | 1983-10-25 | Anibal Galindo | Hypodermic needle |
| US4537593A (en) * | 1983-06-06 | 1985-08-27 | Becton, Dickinson And Co. | Self-venting, non-coring needle assembly |
| US4699612A (en) * | 1985-04-01 | 1987-10-13 | Hamacher Edward N | Infusion needle |
| US4838877A (en) * | 1985-08-06 | 1989-06-13 | Massau Bruce A | Polymeric hypodermic device |
| AT384737B (de) * | 1986-04-04 | 1987-12-28 | Thoma Dipl Ing Dr Techn Herwig | Vorrichtung zur stroemungskonstanten abgabe fluessiger arzneimittel |
| US4886499A (en) * | 1986-12-18 | 1989-12-12 | Hoffmann-La Roche Inc. | Portable injection appliance |
| DK166691D0 (da) * | 1991-09-30 | 1991-09-30 | Unes As | Flerkomponentsproejte |
| US5449351A (en) * | 1993-09-09 | 1995-09-12 | Zohmann; Walter A. | Atraumatic needle for lumbar puncture |
| AT400675B (de) * | 1993-10-18 | 1996-02-26 | Immuno Ag | Spritzengarnitur zur aufbewahrung und applikation eines mehrkomponentenmaterials, spritzenvorrichtung und betätigungseinrichtung hiefür sowie verfahren zum herstellen einer befüllten, sterilen spritzenvorrichtung |
| DE19512607A1 (de) * | 1995-04-04 | 1996-10-10 | Johann Dr Med Rull | Völlig tragmentationsfreie Kanülen |
| FR2749172B1 (fr) * | 1996-05-31 | 1998-11-06 | Multipropulseurs | Seringue hypodermique |
| NZ333321A (en) * | 1996-06-10 | 2000-08-25 | Elan Corp Plc | Needle for subcutaneous delivery of fluids, slots in needle near tip |
| IE80772B1 (en) * | 1996-06-10 | 1999-02-10 | Elan Corp Plc | Delivery needle |
| DE19717253A1 (de) * | 1997-04-24 | 1998-10-29 | Edwin Dr Med Klaus | Universal-Ideal-Nadel |
| US6458095B1 (en) * | 1997-10-22 | 2002-10-01 | 3M Innovative Properties Company | Dispenser for an adhesive tissue sealant having a housing with multiple cavities |
| IT1298087B1 (it) * | 1998-01-08 | 1999-12-20 | Fiderm S R L | Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni |
| US6471670B1 (en) * | 1998-10-05 | 2002-10-29 | Karl Enrenfels | Fibrin sealant applicator system |
| JP2002537031A (ja) * | 1999-02-18 | 2002-11-05 | バイオバルブ テクノロジーズ インコーポレイテッド | 電気活性な細孔 |
| US6517521B1 (en) * | 1999-04-22 | 2003-02-11 | Keith K. Ly | Painless perforated intradermal injection needle |
| US6319230B1 (en) * | 1999-05-07 | 2001-11-20 | Scimed Life Systems, Inc. | Lateral needle injection apparatus and method |
| US6241710B1 (en) * | 1999-12-20 | 2001-06-05 | Tricardia Llc | Hypodermic needle with weeping tip and method of use |
| US6558361B1 (en) * | 2000-03-09 | 2003-05-06 | Nanopass Ltd. | Systems and methods for the transport of fluids through a biological barrier and production techniques for such systems |
| GB0109297D0 (en) * | 2001-04-12 | 2001-05-30 | Glaxosmithkline Biolog Sa | Vaccine |
| US6840921B1 (en) * | 2002-01-11 | 2005-01-11 | Timothy D. Haider | Apparatus and methods for simultaneously administering two or more medications to a patient |
-
2003
- 2003-09-10 WO PCT/US2003/028273 patent/WO2004024219A1/en not_active Ceased
- 2003-09-10 CA CA2498027A patent/CA2498027C/en not_active Expired - Fee Related
- 2003-09-10 AT AT03755805T patent/ATE363310T1/de not_active IP Right Cessation
- 2003-09-10 AU AU2003273306A patent/AU2003273306B2/en not_active Ceased
- 2003-09-10 ES ES03755805T patent/ES2287517T3/es not_active Expired - Lifetime
- 2003-09-10 EP EP03755805A patent/EP1539281B1/en not_active Expired - Lifetime
- 2003-09-10 US US10/659,245 patent/US20040092893A1/en not_active Abandoned
- 2003-09-10 DK DK03755805T patent/DK1539281T3/da active
- 2003-09-10 JP JP2004536400A patent/JP2005537893A/ja active Pending
- 2003-09-10 DE DE60314157T patent/DE60314157T2/de not_active Expired - Lifetime
-
2005
- 2005-07-11 US US11/178,876 patent/US20050245895A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE363310T1 (de) | 2007-06-15 |
| JP2005537893A (ja) | 2005-12-15 |
| US20040092893A1 (en) | 2004-05-13 |
| DE60314157T2 (de) | 2008-01-31 |
| WO2004024219A1 (en) | 2004-03-25 |
| AU2003273306A1 (en) | 2004-04-30 |
| EP1539281B1 (en) | 2007-05-30 |
| AU2003273306B2 (en) | 2009-04-30 |
| US20050245895A1 (en) | 2005-11-03 |
| DE60314157D1 (de) | 2007-07-12 |
| CA2498027A1 (en) | 2004-03-25 |
| CA2498027C (en) | 2012-03-27 |
| EP1539281A1 (en) | 2005-06-15 |
| DK1539281T3 (da) | 2007-10-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2287517T3 (es) | Metodo y aparato para la administracion epidermica de una sustancia. | |
| ES2292601T3 (es) | Administracion de sustancias en la dermis. | |
| ES2329781T3 (es) | Dispositivo y metodo para suministrar o extraer una sustancia a traves de la piel. | |
| ES2273639T3 (es) | Aparato para la administracion por via transdermica de una sustancia. | |
| ES2801973T3 (es) | Dispositivo de administración intradérmica | |
| ES2762899T3 (es) | Dispositivo para administrar por vía intradérmica una substancia | |
| ES2393282T3 (es) | Dispositivo de pluma basado en microaguja para la administración de fármacos | |
| ES2240721T3 (es) | Aguja para la inyeccion de liquido y dispositivo de inyeccion de liquido. | |
| US20080015522A1 (en) | Dual Chamber Injector Integrated With Micro-Needles | |
| MXPA03011611A (es) | Administracion intradermica de vacunas y agentes terapeuticos genicos a traves de microcanula. | |
| JP2004525712A (ja) | 高分子量物質の送出のための方法および装置 | |
| AU2001275853A1 (en) | Needle for intradermal delivery of substances having penetration limiting means | |
| EP2559448A1 (en) | Microneedle adapter for dosed drug delivery devices | |
| CN206621657U (zh) | 一种含有可溶针头的弹性微针 |