ES2287028T3 - Composiciones y metodos para la prevencion o el tratamiento de cancer y de la perdida osea asociada con el cancer. - Google Patents
Composiciones y metodos para la prevencion o el tratamiento de cancer y de la perdida osea asociada con el cancer. Download PDFInfo
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- ES2287028T3 ES2287028T3 ES00955737T ES00955737T ES2287028T3 ES 2287028 T3 ES2287028 T3 ES 2287028T3 ES 00955737 T ES00955737 T ES 00955737T ES 00955737 T ES00955737 T ES 00955737T ES 2287028 T3 ES2287028 T3 ES 2287028T3
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
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- C07K—PEPTIDES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
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- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| US38954599A | 1999-09-03 | 1999-09-03 | |
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| ES2287028T3 true ES2287028T3 (es) | 2007-12-16 |
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| JP (2) | JP2003508491A (cg-RX-API-DMAC7.html) |
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| IL117175A (en) | 1995-02-20 | 2005-11-20 | Sankyo Co | Osteoclastogenesis inhibitory factor protein |
| WO1999058674A2 (en) | 1998-05-14 | 1999-11-18 | Immunex Corporation | Method of inhibiting osteoclast activity |
| ATE497001T1 (de) | 1996-12-23 | 2011-02-15 | Immunex Corp | Rezeptor aktivator von nf-kappa b, rezeptor is mitglied der tnf rezeptor superfamilie |
| JP3523650B2 (ja) | 1997-04-15 | 2004-04-26 | 三共株式会社 | 新規蛋白質及びその製造方法 |
| EA003636B1 (ru) | 1997-04-16 | 2003-08-28 | Амген Инк. | Остеопротегеринсвязующие белки и рецепторы |
| US6316408B1 (en) | 1997-04-16 | 2001-11-13 | Amgen Inc. | Methods of use for osetoprotegerin binding protein receptors |
| WO2000024416A1 (en) * | 1998-10-28 | 2000-05-04 | Snow Brand Milk Products Co., Ltd. | Remedies for bone metabolic errors |
| US20020090646A1 (en) * | 2000-05-03 | 2002-07-11 | Amgen Inc. | Calcitonin-related molecules |
| AU9303001A (en) | 2000-09-22 | 2002-04-02 | Immunex Corp | Screening assays for agonists or antagonists of receptor activat or of nf-kb |
| MXPA03011270A (es) * | 2001-06-06 | 2004-03-18 | Immunex Corp | Uso de antagonistas rank para tratar cancer. |
| EP1270015A3 (en) * | 2001-06-29 | 2004-02-25 | Sankyo Company Limited | A complex comprising OCIF and Polysaccharide |
| AU2003243139B2 (en) | 2002-04-05 | 2007-06-21 | Amgen Inc. | Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors |
| AU2003240754B2 (en) * | 2002-04-10 | 2009-02-26 | Merck Serono Sa | Use of osteoprotegerin for the prevention and/or treatment of fibrosis/sclerosis |
| US7585840B2 (en) | 2002-04-10 | 2009-09-08 | Merck Serono S.A. | Use of osteoprotegerin for the treatment and/or prevention of fibrotic disease |
| US20050287603A1 (en) * | 2002-06-07 | 2005-12-29 | Gorczynski Reginald M | Modulation of bone development |
| CA2587209A1 (en) | 2004-12-13 | 2006-06-22 | Evogenix Ltd | Osteoprotegerin variant proteins |
| TW200714289A (en) * | 2005-02-28 | 2007-04-16 | Genentech Inc | Treatment of bone disorders |
| PT2952191T (pt) * | 2009-06-12 | 2018-11-30 | Sunovion Pharmaceuticals Inc | Apomorfina sublingual |
| CN102242209B (zh) * | 2011-07-05 | 2013-12-11 | 北京大学人民医院 | 基于多个基因辅助诊断多发性骨髓瘤患者的定量检测试剂盒 |
| WO2013147899A1 (en) * | 2012-03-31 | 2013-10-03 | R-PHARM, CJSC (Closed Joint Stock Company) | Osteoprotegerin derived composition and use thereof |
| KR20160127824A (ko) * | 2014-03-06 | 2016-11-04 | 알-팜 오버씨즈, 인코포레이티드 | 오스테오프로테게린 유래의 rankl 억제제 |
| KR101576904B1 (ko) * | 2014-07-31 | 2015-12-14 | (주)케어젠 | 파골세포 분화 및 활성 억제능을 갖는 펩타이드 및 이의 용도 |
| WO2018082758A1 (en) * | 2016-11-04 | 2018-05-11 | Aarhus Universitet | Identification and treatment of tumors characterized by an overexpression of the neonatal fc receptor |
| CN110483647B (zh) * | 2019-08-19 | 2021-02-09 | 重庆大学附属肿瘤医院 | 一种抗肿瘤多肽及其应用 |
| BR112022020809A2 (pt) * | 2020-04-15 | 2023-02-23 | Theradaptive Inc | Composições e métodos para entrega terapêutica direcionada ao osso |
| CA3197104A1 (en) * | 2020-11-11 | 2022-05-19 | Hq Han | Bifunctional antagonists of activin/tgf-beta and rankl and uses thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4710473A (en) * | 1983-08-10 | 1987-12-01 | Amgen, Inc. | DNA plasmids |
| US4925673A (en) * | 1986-08-18 | 1990-05-15 | Clinical Technologies Associates, Inc. | Delivery systems for pharmacological agents encapsulated with proteinoids |
| FR2640537B1 (fr) * | 1988-12-21 | 1992-02-21 | Levy Guy | Installation et procede utilisant l'effet laser, pour la coupe ou la vaporisation de materiaux et tissus divers |
| US5013556A (en) * | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| JP3507486B2 (ja) * | 1991-03-15 | 2004-03-15 | アムジエン・インコーポレーテツド | 顆粒球コロニー刺激因子の肺内投与 |
| US5447851B1 (en) * | 1992-04-02 | 1999-07-06 | Univ Texas System Board Of | Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells |
| ATE311895T1 (de) * | 1992-05-26 | 2005-12-15 | Immunex Corp | Neue zytokine die cd30 binden |
| US5457035A (en) * | 1993-07-23 | 1995-10-10 | Immunex Corporation | Cytokine which is a ligand for OX40 |
| US5843901A (en) * | 1995-06-07 | 1998-12-01 | Advanced Research & Technology Institute | LHRH antagonist peptides |
| US6613544B1 (en) * | 1995-12-22 | 2003-09-02 | Amgen Inc. | Osteoprotegerin |
| US20050147611A1 (en) * | 1995-12-22 | 2005-07-07 | Amgen Inc. | Combination therapy for conditions leading to bone loss |
| US7005413B1 (en) * | 1995-12-22 | 2006-02-28 | Amgen Inc. | Combination therapy for conditions leading to bone loss |
| US6369027B1 (en) * | 1995-12-22 | 2002-04-09 | Amgen Inc. | Osteoprotegerin |
| US20030207827A1 (en) * | 1995-12-22 | 2003-11-06 | William J. Boyle | Osteoprotegerin |
-
2000
- 2000-08-18 KR KR1020017005606A patent/KR20010085996A/ko not_active Ceased
- 2000-08-18 HU HU0104688A patent/HUP0104688A3/hu unknown
- 2000-08-18 ES ES00955737T patent/ES2287028T3/es not_active Expired - Lifetime
- 2000-08-18 CN CN00802472A patent/CN1345246A/zh active Pending
- 2000-08-18 JP JP2001521333A patent/JP2003508491A/ja not_active Withdrawn
- 2000-08-18 DE DE60034871T patent/DE60034871T2/de not_active Expired - Lifetime
- 2000-08-18 EP EP00955737A patent/EP1140136B1/en not_active Expired - Lifetime
- 2000-08-18 WO PCT/US2000/022806 patent/WO2001017543A2/en not_active Ceased
- 2000-08-18 EP EP06022155A patent/EP1800691A3/en not_active Withdrawn
- 2000-08-18 AU AU67889/00A patent/AU6788900A/en not_active Abandoned
- 2000-08-18 AT AT00955737T patent/ATE362374T1/de not_active IP Right Cessation
- 2000-08-18 IL IL14290000A patent/IL142900A0/xx unknown
- 2000-08-18 CA CA2349406A patent/CA2349406C/en not_active Expired - Fee Related
-
2001
- 2001-05-03 ZA ZA200103565A patent/ZA200103565B/en unknown
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2004
- 2004-09-22 US US10/948,053 patent/US20060019887A1/en not_active Abandoned
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2011
- 2011-06-01 JP JP2011123144A patent/JP2011225581A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001017543A2 (en) | 2001-03-15 |
| AU6788900A (en) | 2001-04-10 |
| EP1800691A2 (en) | 2007-06-27 |
| WO2001017543A3 (en) | 2001-07-26 |
| IL142900A0 (en) | 2002-04-21 |
| ZA200103565B (en) | 2002-05-03 |
| EP1800691A3 (en) | 2007-10-31 |
| JP2011225581A (ja) | 2011-11-10 |
| EP1140136B1 (en) | 2007-05-16 |
| DE60034871T2 (de) | 2008-01-17 |
| US20060019887A1 (en) | 2006-01-26 |
| DE60034871D1 (de) | 2007-06-28 |
| CA2349406C (en) | 2011-01-11 |
| EP1140136A2 (en) | 2001-10-10 |
| HUP0104688A3 (en) | 2004-07-28 |
| HUP0104688A2 (hu) | 2002-03-28 |
| CN1345246A (zh) | 2002-04-17 |
| CA2349406A1 (en) | 2001-03-15 |
| JP2003508491A (ja) | 2003-03-04 |
| KR20010085996A (ko) | 2001-09-07 |
| ATE362374T1 (de) | 2007-06-15 |
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