ES2264425T3 - Procedimientos y composiciones para la reconstruccion de estructuras de tejido multicapa. - Google Patents

Procedimientos y composiciones para la reconstruccion de estructuras de tejido multicapa.

Info

Publication number
ES2264425T3
ES2264425T3 ES00984327T ES00984327T ES2264425T3 ES 2264425 T3 ES2264425 T3 ES 2264425T3 ES 00984327 T ES00984327 T ES 00984327T ES 00984327 T ES00984327 T ES 00984327T ES 2264425 T3 ES2264425 T3 ES 2264425T3
Authority
ES
Spain
Prior art keywords
polylayer
cells
bladder
cell
artificial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES00984327T
Other languages
English (en)
Spanish (es)
Inventor
Anthony Atala
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Childrens Medical Center Corp
Original Assignee
Childrens Medical Center Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Medical Center Corp filed Critical Childrens Medical Center Corp
Application granted granted Critical
Publication of ES2264425T3 publication Critical patent/ES2264425T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3886Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
    • A61L27/3891Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types as distinct cell layers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0684Cells of the urinary tract or kidneys
    • C12N5/0685Bladder epithelial cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0697Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1347Smooth muscle cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/25Urinary tract cells, renal cells
    • C12N2502/253Bladder cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Prostheses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ES00984327T 1999-12-29 2000-12-14 Procedimientos y composiciones para la reconstruccion de estructuras de tejido multicapa. Expired - Lifetime ES2264425T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US474524 1999-12-29
US09/474,524 US6428802B1 (en) 1999-12-29 1999-12-29 Preparing artificial organs by forming polylayers of different cell populations on a substrate

Publications (1)

Publication Number Publication Date
ES2264425T3 true ES2264425T3 (es) 2007-01-01

Family

ID=23883889

Family Applications (1)

Application Number Title Priority Date Filing Date
ES00984327T Expired - Lifetime ES2264425T3 (es) 1999-12-29 2000-12-14 Procedimientos y composiciones para la reconstruccion de estructuras de tejido multicapa.

Country Status (9)

Country Link
US (1) US6428802B1 (fr)
EP (1) EP1261692B1 (fr)
JP (1) JP2003527170A (fr)
AT (1) ATE329010T1 (fr)
AU (1) AU778222B2 (fr)
CA (1) CA2395674C (fr)
DE (1) DE60028616T2 (fr)
ES (1) ES2264425T3 (fr)
WO (1) WO2001049827A1 (fr)

Families Citing this family (120)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9711166A (pt) 1996-08-23 1999-08-17 Cook Biotech Inc PrÄtese de enxerto materiais para sua prepara-Æo e m-todos para seu uso
AU747166B2 (en) * 1997-10-31 2002-05-09 Children's Medical Center Corporation Bladder reconstruction
US20030217415A1 (en) * 1998-06-30 2003-11-27 Katrina Crouch Plasticized bone grafts and methods of making and using same
US20100030340A1 (en) * 1998-06-30 2010-02-04 Wolfinbarger Jr Lloyd Plasticized Grafts and Methods of Making and Using Same
US6293970B1 (en) 1998-06-30 2001-09-25 Lifenet Plasticized bone and soft tissue grafts and methods of making and using same
US6734018B2 (en) 1999-06-07 2004-05-11 Lifenet Process for decellularizing soft-tissue engineered medical implants, and decellularized soft-tissue medical implants produced
US7063726B2 (en) * 1998-06-30 2006-06-20 Lifenet Plasticized bone grafts and methods of making and using same
US6743574B1 (en) 2000-09-12 2004-06-01 Lifenet Process for devitalizing soft-tissue engineered medical implants, and devitalized soft-tissue medical implants produced
US8563232B2 (en) 2000-09-12 2013-10-22 Lifenet Health Process for devitalizing soft-tissue engineered medical implants, and devitalized soft-tissue medical implants produced
US20040167634A1 (en) * 1999-05-26 2004-08-26 Anthony Atala Prosthetic kidney and its use for treating kidney disease
EP1404388B1 (fr) * 2001-06-28 2013-10-23 Cook Biotech, Inc. Dispositifs prothetiques de greffe comprenant du collagene de capsules renales
CA2466487C (fr) * 2001-11-16 2011-04-05 Children's Medical Center Corporation Augmentation de la fonction d'un organe
BR0214212A (pt) * 2001-11-16 2004-10-26 Childrens Medical Center Criação de órgãos reprodutores femininos construìdos por tecido
DE10249766A1 (de) 2001-12-04 2003-07-10 Matthias 99086 Erfurt Schreiber Schichtgefässmatrix für den universellen Gewebeaufbau und Vorrichtung zur Inkubation
US20030180268A1 (en) * 2002-02-05 2003-09-25 Anthony Atala Tissue engineered construct for supplementing or replacing a damaged organ
CA2475356A1 (fr) 2002-02-12 2003-08-21 Raven Biotechnologies, Inc. Cellules epitheliales derivees d'une vessie foetale humaine
US20030187515A1 (en) * 2002-03-26 2003-10-02 Hariri Robert J. Collagen biofabric and methods of preparing and using the collagen biofabric
US6958078B2 (en) * 2002-08-19 2005-10-25 The University Of Toledo Bioartificial intervertebral disc
US8940292B2 (en) 2003-01-28 2015-01-27 Wake Forest University Health Sciences Enhancement of angiogenesis to grafts using cells engineered to produce growth factors
US7840263B2 (en) 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
DE102004037184B9 (de) * 2004-07-30 2006-01-05 Technische Universität Dresden Gewebetransplantatkonstrukt zur Rekonstruktion eines menschlichen oder tierischen Organs
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
US8060219B2 (en) 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US8874204B2 (en) * 2004-12-20 2014-10-28 Cardiac Pacemakers, Inc. Implantable medical devices comprising isolated extracellular matrix
US20100203638A1 (en) * 2005-02-15 2010-08-12 School Juridical Person Kitasato Gakuen Method of Producing High-Density Cultured Tissue and High-Density Cultured Tissue
US20060199265A1 (en) * 2005-03-02 2006-09-07 Wolf Michael F Seeding implantable medical devices with cells
US7759120B2 (en) * 2005-03-02 2010-07-20 Kps Bay Medical, Inc. Seeding implantable medical devices with cells
US20060204539A1 (en) 2005-03-11 2006-09-14 Anthony Atala Electrospun cell matrices
US20060204445A1 (en) * 2005-03-11 2006-09-14 Anthony Atala Cell scaffold matrices with image contrast agents
WO2006099332A2 (fr) * 2005-03-11 2006-09-21 Wake Forest University Health Sciences Production par genie tissulaire de doigts, d'orteils et de membres
AU2006223063B2 (en) * 2005-03-11 2011-11-17 Wake Forest University Health Sciences Tissue engineered blood vessels
AU2006223112B2 (en) 2005-03-11 2011-12-01 Wake Forest University Health Sciences Production of tissue engineered heart valves
EP2460875A1 (fr) 2005-03-31 2012-06-06 Stemnion, Inc. Compositions cellulaires dérivées d'amnios, procédés de fabrication et utilisations associées
DE102005017000B4 (de) * 2005-04-13 2007-10-04 Technische Universität Dresden Verfahren zur Herstellung eines Gewebetransplantatkonstruktes zur Rekonstruktion eines menschlichen oder tierischen Organs
EP1902127B1 (fr) * 2005-04-15 2012-08-29 Wake Forest University Health Sciences Système de bioréacteur et procédé destiné à améliorer la fonctionnalité du muscle cultivé in vitro
WO2007005807A2 (fr) * 2005-06-30 2007-01-11 Anthrogenesis Corporation Reparation de la membrane du tympan a l'aide de tissu biologique de collagene derive du placenta
JP5416415B2 (ja) * 2006-02-10 2014-02-12 テンジオン, インコーポレイテッド 臓器の再建および増強のための骨格
DE102006009539A1 (de) * 2006-02-28 2007-09-06 Technische Universität Dresden Prävaskularisierte Gewebetransplantatkonstrukte zur Rekonstruktion eines menschlichen oder tierischen Organs
GB0606231D0 (en) 2006-03-29 2006-05-10 Univ Leeds Improvements relating to decellurisation of tissue matrices for bladder implantation
GB2440054B (en) * 2006-03-29 2008-08-06 Univ Leeds Native decellularised bladder tissue
MX2008015645A (es) * 2006-06-09 2009-02-06 Anthrogenesis Corp Nicho placentario y uso de este para cultivar celulas primordiales.
US8105634B2 (en) * 2006-08-15 2012-01-31 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
WO2008042441A1 (fr) * 2006-10-03 2008-04-10 Anthrogenesis Corporation Utilisation de biomatériau de cordon ombilical en chirurgie oculaire
WO2008060377A2 (fr) 2006-10-04 2008-05-22 Anthrogenesis Corporation Compositions de tissu du cordon ombilical ou placentaire
EP2076279B1 (fr) 2006-10-06 2014-08-27 Anthrogenesis Corporation Compositions de collagène de placenta humain et procédés de fabrication et d'utilisation de celles-ci
CZ300805B6 (cs) * 2007-01-23 2009-08-12 Ústav experimentální medicíny AV CR Biomateriál na bázi nanovlákenných vrstev a zpusob jeho prípravy
CZ301002B6 (cs) * 2007-01-23 2009-10-07 Ústav experimentální medicíny AV CR, v.v.i. Biomateriál na bázi nanovlákenné vrstvy a zpusob jeho prípravy
AU2008245900B2 (en) * 2007-04-24 2013-07-25 Advanced Technologies And Regenerative Medicine, Llc Engineered renal tissue
JP2010528658A (ja) 2007-06-08 2010-08-26 ウェイク・フォレスト・ユニヴァーシティ・ヘルス・サイエンシズ 腎不全の治療のための選択的細胞治療
US9744043B2 (en) 2007-07-16 2017-08-29 Lifenet Health Crafting of cartilage
EP2022511A1 (fr) 2007-08-06 2009-02-11 Corlife GbR Revêtement bioactif pour un dispositif implantable ou une bioprothèse
US11051733B2 (en) * 2008-01-18 2021-07-06 Wake Forest University Health Sciences Isolating and purifying cells for therapy
US10448989B2 (en) 2009-04-09 2019-10-22 Virginia Tech Intellectual Properties, Inc. High-frequency electroporation for cancer therapy
US8992517B2 (en) 2008-04-29 2015-03-31 Virginia Tech Intellectual Properties Inc. Irreversible electroporation to treat aberrant cell masses
US9198733B2 (en) 2008-04-29 2015-12-01 Virginia Tech Intellectual Properties, Inc. Treatment planning for electroporation-based therapies
AU2009243079A1 (en) * 2008-04-29 2009-11-05 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation to create tissue scaffolds
US10702326B2 (en) 2011-07-15 2020-07-07 Virginia Tech Intellectual Properties, Inc. Device and method for electroporation based treatment of stenosis of a tubular body part
US10272178B2 (en) 2008-04-29 2019-04-30 Virginia Tech Intellectual Properties Inc. Methods for blood-brain barrier disruption using electrical energy
US10238447B2 (en) 2008-04-29 2019-03-26 Virginia Tech Intellectual Properties, Inc. System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress
US10245098B2 (en) 2008-04-29 2019-04-02 Virginia Tech Intellectual Properties, Inc. Acute blood-brain barrier disruption using electrical energy based therapy
US9867652B2 (en) 2008-04-29 2018-01-16 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds
US11254926B2 (en) 2008-04-29 2022-02-22 Virginia Tech Intellectual Properties, Inc. Devices and methods for high frequency electroporation
US9283051B2 (en) 2008-04-29 2016-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating a treatment volume for administering electrical-energy based therapies
US11272979B2 (en) 2008-04-29 2022-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US7927414B2 (en) 2008-09-05 2011-04-19 Ethicon, Inc. Method of manufacturing acellular matrix glue
US8858698B2 (en) 2008-09-05 2014-10-14 Mentor Worldwide Llc Acellular matrix glue
KR20170041279A (ko) * 2008-11-04 2017-04-14 리젠메드 (케이만) 엘티디. 세포-지지체 구조물
WO2010057013A1 (fr) 2008-11-14 2010-05-20 Wake Forest University Health Sciences Therapie cellulaire selective pour le traitement d'insuffisance renale
WO2010057015A1 (fr) 2008-11-14 2010-05-20 Wake Forest University Health Sciences Structures de rein et leurs procedes de formation
JP2010172247A (ja) * 2009-01-29 2010-08-12 Kitasato Institute 積層型高密度培養人工組織の製造方法及び積層型高密度培養人工組織
US11638603B2 (en) 2009-04-09 2023-05-02 Virginia Tech Intellectual Properties, Inc. Selective modulation of intracellular effects of cells using pulsed electric fields
US11382681B2 (en) 2009-04-09 2022-07-12 Virginia Tech Intellectual Properties, Inc. Device and methods for delivery of high frequency electrical pulses for non-thermal ablation
WO2010138919A2 (fr) 2009-05-28 2010-12-02 Angiodynamics, Inc. Système et méthode de synchronisation de l'apport d'énergie et du rythme cardiaque
US9895189B2 (en) 2009-06-19 2018-02-20 Angiodynamics, Inc. Methods of sterilization and treating infection using irreversible electroporation
US20110065809A1 (en) * 2009-09-15 2011-03-17 Medtronic, Inc. Polymerization of Multifunctional Azides, and Polymers Therefrom
US10500384B2 (en) * 2010-01-08 2019-12-10 Wake Forest University Health Sciences Delivery system
CA2791736A1 (fr) * 2010-03-09 2011-09-15 Tengion, Inc. Constructions supports de cellules
DE102010020222A1 (de) 2010-05-11 2011-11-17 Axel Haverich Verfahren zur Herstellung einer Organnachbildung, insbesondere eines Funktionsmodells
DE102010023156B4 (de) * 2010-06-02 2012-07-05 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. In vitro-Testsystem für virale Infektionen
SG10201706641TA (en) 2010-09-22 2017-09-28 Univ Nanyang Tech Method for forming a tissue construct and use thereof
US9677042B2 (en) 2010-10-08 2017-06-13 Terumo Bct, Inc. Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
WO2012051433A2 (fr) 2010-10-13 2012-04-19 Angiodynamics, Inc. Système et procédé d'ablation électrique des tissus chez un patient
US20130013083A1 (en) * 2011-01-06 2013-01-10 Humacyte Tissue-Engineered Constructs
EP2661243B1 (fr) 2011-01-06 2022-10-12 Humacyte, Inc. Constructions obtenues par génie tissulaire
CA2828705A1 (fr) 2011-03-07 2012-09-13 Wake Forest University Health Sciences Systeme d'administration
US9517083B2 (en) * 2011-09-16 2016-12-13 Boston Scientific Scimed, Inc. Apparatus for treating an organ and related methods of use
US9078665B2 (en) 2011-09-28 2015-07-14 Angiodynamics, Inc. Multiple treatment zone ablation probe
CN102488569B (zh) * 2011-11-15 2014-07-23 西安交通大学 一种立体微流道多孔支架的分层制造方法
CN102512266B (zh) * 2012-01-16 2015-04-29 杭州电子科技大学 脊髓损伤修复组织工程支架的制备方法
US11311367B2 (en) 2012-01-31 2022-04-26 Wake Forest University Health Sciences Tissue-engineered gut-sphincter complexes and methods of making the same
US9414881B2 (en) 2012-02-08 2016-08-16 Angiodynamics, Inc. System and method for increasing a target zone for electrical ablation
EP2841010B1 (fr) 2012-04-24 2023-08-23 Harvard Apparatus Regenerative Technology, Inc. Supports pour échafaudages tissulaires modifiés
US11284987B2 (en) 2013-01-09 2022-03-29 Biostage, Inc. Synthetic scaffolds
EP2970877B1 (fr) * 2013-03-15 2018-07-25 Wake Forest University Health Sciences Différenciation de cellules progénitrices neurales
US10092679B2 (en) 2013-10-18 2018-10-09 Wake Forest University Health Sciences Laminous vascular constructs combining cell sheet engineering and electrospinning technologies
WO2015073913A1 (fr) 2013-11-16 2015-05-21 Terumo Bct, Inc. Expansion de cellules dans un bioréacteur
US20160303284A1 (en) * 2013-12-03 2016-10-20 Cornell University Method of repairing an annulus and collagen gel composition
JP6783143B2 (ja) 2014-03-25 2020-11-11 テルモ ビーシーティー、インコーポレーテッド 培地の受動的補充
EP3143124A4 (fr) 2014-05-12 2018-01-17 Virginia Tech Intellectual Properties, Inc. Modulation sélective des effets intracellulaires des cellules à l'aide de champs électriques pulsés
US12114911B2 (en) 2014-08-28 2024-10-15 Angiodynamics, Inc. System and method for ablating a tissue site by electroporation with real-time pulse monitoring
WO2016049421A1 (fr) 2014-09-26 2016-03-31 Terumo Bct, Inc. Alimentation programmée
US10694972B2 (en) 2014-12-15 2020-06-30 Virginia Tech Intellectual Properties, Inc. Devices, systems, and methods for real-time monitoring of electrophysical effects during tissue treatment
US10751448B2 (en) 2015-01-12 2020-08-25 Wake Forest University Health Sciences Multi-layer skin substitute products and methods of making and using the same
US10179190B2 (en) 2015-05-29 2019-01-15 Boston Scientific Scimed, Inc. Compositions and methods for treatment of tissue
WO2017004592A1 (fr) 2015-07-02 2017-01-05 Terumo Bct, Inc. Croissance cellulaire à l'aide de stimuli mécaniques
WO2017044787A1 (fr) * 2015-09-10 2017-03-16 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Échafaudages de matrice extracellulaire bicouche et leurs utilisations
US20190015190A1 (en) 2015-12-30 2019-01-17 Wake Forest University Health Sciences Tissue-engineered gut-sphincter complexes and methods of making the same
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US10905492B2 (en) 2016-11-17 2021-02-02 Angiodynamics, Inc. Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode
KR101849737B1 (ko) 2016-12-27 2018-04-18 한국기계연구원 인공 장 및 그 제조 방법
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
JP7393945B2 (ja) 2017-03-31 2023-12-07 テルモ ビーシーティー、インコーポレーテッド 細胞増殖
US11607537B2 (en) 2017-12-05 2023-03-21 Virginia Tech Intellectual Properties, Inc. Method for treating neurological disorders, including tumors, with electroporation
US11311329B2 (en) 2018-03-13 2022-04-26 Virginia Tech Intellectual Properties, Inc. Treatment planning for immunotherapy based treatments using non-thermal ablation techniques
US11925405B2 (en) 2018-03-13 2024-03-12 Virginia Tech Intellectual Properties, Inc. Treatment planning system for immunotherapy enhancement via non-thermal ablation
US11950835B2 (en) 2019-06-28 2024-04-09 Virginia Tech Intellectual Properties, Inc. Cycled pulsing to mitigate thermal damage for multi-electrode irreversible electroporation therapy
US12043823B2 (en) 2021-03-23 2024-07-23 Terumo Bct, Inc. Cell capture and expansion

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4458678A (en) 1981-10-26 1984-07-10 Massachusetts Institute Of Technology Cell-seeding procedures involving fibrous lattices
US4520821A (en) 1982-04-30 1985-06-04 The Regents Of The University Of California Growing of long-term biological tissue correction structures in vivo
US5160490A (en) 1986-04-18 1992-11-03 Marrow-Tech Incorporated Three-dimensional cell and tissue culture apparatus
US5266480A (en) 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
US5902741A (en) 1986-04-18 1999-05-11 Advanced Tissue Sciences, Inc. Three-dimensional cartilage cultures
US4963489A (en) 1987-04-14 1990-10-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5863531A (en) 1986-04-18 1999-01-26 Advanced Tissue Sciences, Inc. In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework
US5032508A (en) 1988-09-08 1991-07-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5804178A (en) 1986-11-20 1998-09-08 Massachusetts Institute Of Technology Implantation of cell-matrix structure adjacent mesentery, omentum or peritoneum tissue
CA1340581C (fr) 1986-11-20 1999-06-08 Joseph P. Vacanti Neomorphogenese chimerique d'organes par implatation cellulaire controlee, utilisant des matrices artificielles
US5567612A (en) 1986-11-20 1996-10-22 Massachusetts Institute Of Technology Genitourinary cell-matrix structure for implantation into a human and a method of making
WO1989001967A1 (fr) 1987-09-03 1989-03-09 Brown University Research Foundation Purification du sang a l'aide de cellules renales cultivees
US4996154A (en) * 1989-05-04 1991-02-26 Millipore Corporation Method for growing cellular tissue
AU2900792A (en) 1991-10-24 1993-05-21 Children's Medical Center Corporation Neomorphogenesis of urological structures in vivo from cell culture
US5800537A (en) * 1992-08-07 1998-09-01 Tissue Engineering, Inc. Method and construct for producing graft tissue from an extracellular matrix
US5916265A (en) 1994-03-30 1999-06-29 Hu; Jie Method of producing a biological extracellular matrix for use as a cell seeding scaffold and implant
US5695998A (en) 1995-02-10 1997-12-09 Purdue Research Foundation Submucosa as a growth substrate for islet cells
WO1996031232A1 (fr) 1995-04-07 1996-10-10 Purdue Research Foundation Greffe de tissus et procede de reconstitution de vessie
US5855610A (en) 1995-05-19 1999-01-05 Children's Medical Center Corporation Engineering of strong, pliable tissues
CA2263144A1 (fr) 1996-08-16 1998-02-19 Children's Medical Center Corporation Sous-muqueuse vesicale ensemencee par des cellules pour la reconstitution de son tissu
JP4023828B2 (ja) 1996-09-05 2007-12-19 チルドレンズ・メディカル・センター・コーポレーション 人工腎臓および腎臓疾患治療へのその利用
AU747166B2 (en) 1997-10-31 2002-05-09 Children's Medical Center Corporation Bladder reconstruction

Also Published As

Publication number Publication date
EP1261692A1 (fr) 2002-12-04
JP2003527170A (ja) 2003-09-16
AU778222B2 (en) 2004-11-25
ATE329010T1 (de) 2006-06-15
US6428802B1 (en) 2002-08-06
DE60028616D1 (de) 2006-07-20
EP1261692B1 (fr) 2006-06-07
DE60028616T2 (de) 2007-01-11
WO2001049827A1 (fr) 2001-07-12
CA2395674A1 (fr) 2001-07-12
AU2096301A (en) 2001-07-16
CA2395674C (fr) 2007-02-06

Similar Documents

Publication Publication Date Title
ES2264425T3 (es) Procedimientos y composiciones para la reconstruccion de estructuras de tejido multicapa.
US6479064B1 (en) Culturing different cell populations on a decellularized natural biostructure for organ reconstruction
EP2292278B1 (fr) Augmentation de la fonction d'un organe
Nishida et al. Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium
ES2219432T3 (es) Cabestrillos o parches fasciales artificiales.
JP3073766B2 (ja) 重合マトリックス上の大容量の細胞の移植方法
JPWO2005087286A1 (ja) 生体組織シート及びその作製方法、並びに同シートを用いる移植方法
CN113559124B (zh) 间充质干细胞凋亡小体在制备治疗骨缺损的药物中的应用
WO2011023843A2 (fr) Élaboration de tissus artificiels par ingénierie tissulaire au moyen de biomatériaux de fibrine et d'agarose
JPWO2005047496A1 (ja) 細胞培養法、細胞の三次元培養法、三次元組織、人工臓器、及び組織移植方法
ES2362139B1 (es) Elaboración de tejidos artificiales mediante ingeniería tisular utilizando biomateriales de fibrina, agarosa y colágeno.
松尾夏来 Transplantation of hybrid adipose-derived stem cell sheet with autologous peritoneum: An in vivo feasibility study
US20210196760A1 (en) Pharmaceutical composition for treating cartilage damage, comprising nasal septum chondrocytes
AU2004202491B2 (en) Reconstructing organs from decellularized biomaterial scaffold
AU2007201136B2 (en) Augmentation of organ function
AU2011202672A1 (en) Augmentation of organ function